Method for manufacturing absorbable composite biomaterial, absorbable biomaterial produced and use thereof in various applications

The described method addresses the degradation and mechanical performance issues of composite biomaterials by using pressure compaction and low-temperature sintering to create a stable, biocompatible composite for bone repair and implant applications.

CN120322260APending Publication Date: 2025-07-15UNIV CLAUDE BERNARD LYON 1 +2
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Patent Information

Application Number
CN202380083897.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Priority Date
2022-12-06
Filing Date
2023-12-05
Publication Date
2025-07-15

AI Technical Summary

Technical Problem

In the manufacture of biodegradable synthetic polymer-ceramic composites, the polymer matrix has problems such as excessive hydrolysis and degradation speed, poor mechanical properties, and inconvenient solvent use during processing, resulting in the implant losing its mechanical properties before bone healing or triggering an inflammatory response.

Method used

Composite biomaterials are manufactured by compacting and sintering methods. By compacting biocompatible absorbable organic polymers and bioactive inorganic material powder at low temperatures, and then sintering at low temperatures, forming a tightly bound solid, avoiding polymer melting and solvent use at high temperatures, ensuring the stability and mechanical properties of the polymer matrix.

Benefits of technology

It improves the mechanical properties and stability of composite biological materials, reduces hydrolysis and degradation, simplifies the manufacturing process, reduces the use of solvents, and is suitable for orthopedic implants, avoids inflammatory reactions and mechanical performance losses caused by degradation.

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Abstract

The present invention relates to a method for manufacturing a composite biomaterial comprising at least one biocompatible absorbable organic polymer and at least one biologically active inorganic material, to a composite biomaterial obtained by said method, to an implantable device comprising said composite biomaterial, said composite biomaterial for medical use, in particular for medical use. Or as a bone substitute or for supporting bone regeneration, as well as a sterilization method for implementing the composite biomaterial.
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