Novel crystal form of spinosad and preparation method thereof
By preparing SN-II and SN-III crystal forms of spinosad, the problems of storage instability of amorphous spinosad and high energy consumption and high cost of existing preparation methods have been solved, realizing efficient and stable production of spinosad crystal forms, which are suitable for industrial applications.
CN122127382APending Publication Date: 2026-06-02XINJIANG TIANFU SUNSHINE BIOTECHNOLOGY CO LTD
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Patent Information
- Application Number
- CN202610319238.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-03-16
- Publication Date
- 2026-06-02
AI Technical Summary
Technical Problem
The amorphous state of existing spinosads exhibits high aggregation during storage, and existing preparation methods are energy-intensive, costly, and potentially environmentally harmful, making them unsuitable for industrial production.
Method used
Two new crystal forms of spinosad, SN-II and SN-III, were developed and prepared using a specific solvent system and temperature control method, including steps such as heating and stirring, and cooling and crystallization, to obtain stable spinosad crystal forms.
Benefits of technology
The prepared SN-II and SN-III crystal forms are simple to operate, have stable quality, high yield, high purity, and good chemical stability, making them suitable for industrial production and drug research.
✦ Generated by Eureka AI based on patent content.
Abstract
The invention discloses a novel crystal form of spinosad and a preparation method thereof, and belongs to the field of biological medicine. The novel crystal forms SN-II and SN-III provided by the invention overcome the defect of instability of amorphous spinosad sold in the market, are convenient for industrial production and have better economical efficiency.
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