Protein mutant, xanthan gum producing strain containing the protein mutant and application
The mutant strain HXC001a of Xanthomonas was screened by atmospheric pressure and room temperature plasma mutagenesis. It was found that the T1158P mutation of the XCC2846 gene increased xanthan gum production, which solved the problems of insufficient yield and genetic stability in the existing technology and realized high-yield and stable industrial application.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- TIANJIN HERUN BIOTECHNOLOGY CO LTD
- Filing Date
- 2026-06-11
- Publication Date
- 2026-07-17
AI Technical Summary
In existing technologies, there is still room for improvement in the xanthan gum yield, fermentation efficiency, and industrial adaptability of wild-type Xanthomonas. The genetic basis of high-yield strains selected by traditional mutagenesis screening is unclear, which limits the targeted modification and stable genetic utilization.
Xanthomonas mutant strain HXC001a was screened by ambient pressure room temperature plasma mutagenesis (ARTP). It was found that the mutation of the T1158P protein encoded by the XCC2846 gene significantly increased xanthan gum production. A high-yield xanthan gum production strain CGMCC No.38053 was constructed, achieving both genetic stability and yield improvement.
Xanthan gum yield increased by 36.9%, exhibited good genetic stability, and is suitable for industrial fermentation production, reducing production costs.
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Figure CN122404504A_ABST