Probe type ultrasonic instrument

By introducing a liquid level sensor and automatic adjustment system into the probe-type ultrasonicer, the problem of inefficient probe height adjustment is solved, and a more efficient and accurate DNA interruption process is achieved.

CN222631447UActive Publication Date: 2025-03-18TAIZHOU VOCATIONAL COLLEGE OF SCI & TECH
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Patent Information

Application Number
CN202420451284.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-03-08
Publication Date
2025-03-18
Estimated Expiration
2034-03-08

AI Technical Summary

Technical Problem

When using a probe-type ultrasound machine for DNA interruption, the probe height needs to be adjusted manually, resulting in inefficiency, especially when the sample size is small, the liquid level height is inconsistent, and a lot of time is required to be used for manual adjustment.

Method used

A probe-type ultrasonicator is designed, equipped with a liquid level sensor and an automatic adjustment system. The liquid level sensor detects the distance the probe enters the liquid. The processor controls the driving source to automatically adjust the probe height to ensure that the probe is always in the correct position.

Benefits of technology

Through the combination of the liquid level sensor and the automatic adjustment system, the efficiency of DNA interruption is significantly improved, the time of artificial adjustment is reduced, the probe is accurate in position in all samples, and the quality of interruption is improved.

✦ Generated by Eureka AI based on patent content.

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  • Figure CN222631447U_ABST
    Figure CN222631447U_ABST
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Abstract

The utility model provides a probe type ultrasonic instrument which comprises a rack, an ultrasonic host and a processor are arranged at the upper end of the rack, a sample fixing piece is arranged at the lower end of the rack, a test tube body used for bearing solution is arranged in the sample fixing piece, a probe is fixedly arranged below the ultrasonic host, and a liquid level sensor is arranged at the side end of the probe. The liquid level sensor is electrically connected with the processor and generates electric signals to the processor when making contact with the liquid level, a first driving source is further arranged at the bottom of the sample fixing piece, the sample fixing piece is fixedly arranged at the output end of the first driving source, and the processor controls starting and stopping of the first driving source and drives the sample fixing piece to stop at the designated position. The distance of the probe entering the liquid is detected through the liquid level sensor, so that the probe is quickly and accurately moved to a required position when DNA is broken, the situation that a large amount of time is spent on manual adjustment of equipment is avoided, and the efficiency is improved.
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Description

Technical Field

[0001] The utility model relates to an ultrasonic instrument, in particular to a probe type ultrasonic instrument. Background Art

[0002] In the process of studying DNA, scientists often need to break DNA for further research and analysis. Common methods of breaking DNA are through ultrasound or enzymatic hydrolysis. Ultrasonic breaking is to shear the DNA fragments in the solution through the shear force generated by ultrasound.

[0003] At present, a Chinese patent with announcement number CN220294878U discloses an ultrasonic interrupter that is convenient for adjusting the actual angle, including an interrupter body, a clamp and a bracket. A rotating motor is arranged in the clamp, and the rotating motor is connected to a first gear. A second gear is meshed at the side end of the first gear. The rotating motor drives the first gear and the second gear to rotate through a rotating shaft to achieve the function of adjusting the interrupter.

[0004] The above patent still has shortcomings. When using a probe-type ultrasonic instrument for DNA shearing, the probe needs to be inserted into the liquid surface about 10 mm, and the probe cannot touch the tube wall during the ultrasonic process. When the number of research samples is small, it is impossible to ensure that the liquid level height of all samples remains consistent. Therefore, a lot of time is required to manually adjust the equipment, and the shearing efficiency is low. Utility Model Content

[0005] In view of this, an object of the present invention is to provide a probe-type ultrasound instrument having a function of automatically adjusting the height of the probe.

[0006] In order to solve the above technical problems, the technical solution of the utility model is: a probe-type ultrasonic instrument, comprising a frame, an ultrasonic host and a processor are arranged at the upper end of the frame, a sample fixture is arranged at the lower end of the frame, a test tube body for carrying a solution is arranged in the sample fixture, a probe is fixedly arranged below the ultrasonic host, a liquid level sensor is arranged at the side end of the probe, the liquid level sensor is electrically connected to the processor and generates an electrical signal to the processor when it contacts the liquid surface, a driving source 1 is also arranged at the bottom of the sample fixture, the sample fixture is fixedly arranged at the output end of the driving source 1, the processor controls the start and stop of the driving source 1, and drives the sample fixture to stop at a specified position.

[0007] Preferably, the sample fixing member comprises a fixing block, a test tube hole is formed on the top of the fixing block, the test tube body is detachably arranged in the test tube hole, and a tube pressing member is further arranged on the outside of the test tube, and the tube pressing member is used to fix the test tube body.

[0008] Preferably, the pipe pressing member comprises a pipe sleeve, an inclined hole is formed on the inner side of the pipe sleeve, a rubber layer is provided on the side of the inclined hole, a thread is further provided on the outer side of the pipe sleeve, the pipe sleeve is threadedly connected to the test tube hole, and the outer side surface of the test tube body is an inclined surface.

[0009] Preferably, a plurality of probes are fixedly arranged at the bottom of the ultrasonic main unit, and a number of test tube holes matching the number of the probes is opened at the top of the sample fixture.

[0010] Preferably, a liquid level sensor is provided at the side end of the probe, the fixed block includes a mounting seat and a mounting block, the test tube hole is opened on the mounting block, a plurality of slide grooves are opened in the mounting seat, the mounting block is slidably set in the slide grooves, and two driving sources whose number is the same as the mounting blocks are also provided in the mounting seat, and the two driving sources respectively control the up and down movement of the mounting seat.

[0011] Preferably, the driving source 1 includes a linear motor, the mounting seat is fixedly arranged at the output end of the linear motor, the driving source 2 includes a servo motor, a screw is fixed at the output end of the servo motor, a screw hole is opened at the bottom of the mounting block, and the screw is threadedly connected to the screw hole.

[0012] Compared with the prior art, the beneficial effects of the utility model are:

[0013] 1. The liquid level sensor detects the distance the probe enters the liquid, so that the probe can be quickly and accurately moved to the required position during DNA fragmentation, avoiding a lot of time spent on manual adjustment of the equipment and increasing efficiency;

[0014] 2. Fix the test tube body through the tube sleeve to prevent the test tube body from tilting and causing the probe to touch the test tube wall;

[0015] 3. By setting up multiple probes and test tube bodies, the breaking efficiency of the equipment is increased. By setting a second driving source at the bottom of all mounting blocks, when the liquid level height in the test tube body is different, it can be adjusted for different test tube bodies to increase the breaking quality. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a structural schematic diagram of embodiment 1;

[0017] Figure 2 It is a partial schematic diagram of the first embodiment;

[0018] Figure 3 is a schematic diagram of the structure of the casing;

[0019] Figure 4 It is a structural schematic diagram of the second embodiment;

[0020] Figure 5It is a partial schematic diagram of the second embodiment.

[0021] Figure numerals: 1, frame; 2, ultrasonic host; 3, sample fixing part; 4, test tube body; 5, probe; 6, liquid level sensor; 7, driving source one; 8, fixing block; 9, test tube hole; 10, tube sleeve; 11, inclined hole; 12, rubber layer; 13, mounting seat; 14, mounting block; 15, slide groove; 16, driving source two; 17, screw; 18, screw hole. DETAILED DESCRIPTION

[0022] The specific implementation modes of the present invention are further described below in conjunction with the accompanying drawings to make the technical solutions of the present invention easier to understand and grasp.

[0023] Embodiment 1:

[0024] A probe-type ultrasound machine, such as Figure 1-Figure 3 As shown, it includes a frame 1, an ultrasonic host 2 and a processor are arranged on the upper end of the frame 1, a sample fixture 3 is arranged on the lower end of the frame 1, a test tube body 4 for carrying a solution is arranged in the sample fixture 3, a probe 5 is fixedly arranged below the ultrasonic host 2, a liquid level sensor 6 is arranged on the side end of the probe 5, the liquid level sensor 6 is arranged on the upper side of the probe 5, the end face of the liquid level sensor 6 is 10mm different from the end face of the probe 5, the liquid level sensor 6 is electrically connected to the processor and generates an electrical signal to the processor when it contacts the liquid surface, at this time the probe 5 enters 10mm into the liquid, a driving source 7 is also arranged at the bottom of the sample fixture 3, the driving source 7 includes a linear motor, the sample fixture 3 is fixedly arranged at the output end of the driving source 7, the processor controls the start and stop of the driving source 7, when the linear motor drives the sample fixture 3 to move upward, the liquid level sensor 6 gradually approaches the test tube body 4, when the liquid contacts the liquid level sensor 6, the liquid level sensor 6 sends an electrical signal to the processor, the processor drives the linear motor to stop urgently, at this time the test tube body 4 stays at the specified position and stops, thereby avoiding spending a lot of time on manual adjustment of the equipment and increasing efficiency.

[0025] The sample fixing part 3 includes a fixing block 8, a test tube hole 9 is provided on the top of the fixing block 8, and the test tube body 4 can be detachably arranged in the test tube hole 9. After the interruption is completed, the test tube body 4 can be disassembled and replaced. A pressing tube piece is also provided on the outside of the test tube, and the pressing tube piece is used to fix the test tube body 4. The pressing tube piece includes a tube sleeve 10, an inclined hole 11 is provided on the inner side of the tube sleeve 10, and a rubber layer 12 is provided on the side of the inclined hole 11. The outer side surface of the test tube body 4 is an inclined surface, and its inclination angle is relatively consistent with the inclined hole 11. A thread is also provided on the outside of the tube sleeve 10. The test tube hole 9 is a countersunk hole, and the bottom of the test tube hole 9 cooperates with the bottom of the test tube body 4. The countersunk part of the test tube hole 9 is threadedly connected with the outer side of the sleeve. When installing the test tube body 4, the sleeve 10 is placed on the outside of the test tube body 4, and then the test tube body 4 is inserted into the test tube hole 9, and the sleeve is rotated to press the sleeve against the test tube body 4, thereby keeping the test tube body 4 stable.

[0026] Embodiment 2:

[0027] The difference between the second embodiment and the first embodiment is that Figure 4-Figure 5 As shown, four probes 5 are fixedly arranged at the bottom of the ultrasonic host 2, and the top of the sample fixing part 3 is provided with test tube holes 9 with the same number as the probes 5, and the test tube bodies 4 can be placed in the test tube holes 9. The side ends of the probes 5 are provided with liquid level sensors 6, so as to increase the interruption efficiency of the equipment. The fixing block 8 includes a mounting seat 13 and a mounting block 14, and the test tube holes 9 are provided on the mounting block 14. A plurality of slide grooves 15 are provided in the mounting seat 13, and the mounting block 14 is slidably arranged in the slide grooves 15. The mounting seat 13 is fixedly arranged on a driving source 7, and the driving source 7 drives the four test tube bodies 4 to move up and down at the same time.

[0028] The mounting seat 13 is also provided with driving source two 16 of the same number as the mounting block 14, and the driving source two 16 includes a servo motor, and a screw 17 is fixed to the output end of the servo motor. A screw hole 18 is provided at the bottom of the mounting block 14, and the screw 17 is threadedly connected to the screw hole 18. The four driving sources two 16 respectively control the four mounting seats 13 to move up and down. When the liquid level height in the test tube body 4 is different, the driving source two 16 can adjust the height of the test tube body 4 according to the liquid level conditions in different test tube bodies 4, so that the probe 5 can be inserted into the liquid surface 10 mm, thereby increasing the interruption quality.

[0029] Of course, the above are only typical examples of the present invention. In addition, the present invention may have many other specific implementations. Any technical solutions formed by equivalent replacement or equivalent transformation fall within the scope of protection required by the present invention.

Claims

1. A probe-type ultrasound instrument, comprising a frame (1), characterized in that: An ultrasonic main unit (2) and a processor are arranged at the upper end of the frame (1), a sample fixing part (3) is arranged at the lower end of the frame (1), a test tube body (4) for carrying a solution is arranged in the sample fixing part (3), a probe (5) is fixedly arranged below the ultrasonic main unit (2), a liquid level sensor (6) is arranged at the side end of the probe (5), the liquid level sensor (6) is electrically connected to the processor and generates an electrical signal to the processor when it contacts the liquid surface, a driving source (7) is also arranged at the bottom of the sample fixing part (3), the sample fixing part (3) is fixedly arranged at the output end of the driving source (7), the processor controls the start and stop of the driving source (7), and drives the sample fixing part (3) to stop at a specified position.

2. A probe-type ultrasonic instrument according to claim 1, characterized in that: The sample fixing member (3) comprises a fixing block (8), a test tube hole (9) is provided on the top of the fixing block (8), the test tube body (4) is detachably arranged in the test tube hole (9), and a tube pressing member is also arranged on the outside of the test tube, and the tube pressing member is used to fix the test tube body (4).

3. A probe-type ultrasonic instrument according to claim 2, characterized in that: The pipe pressing member comprises a pipe sleeve (10), an inclined hole (11) is provided on the inner side of the pipe sleeve (10), a rubber layer (12) is provided on the side of the inclined hole (11), a thread is further provided on the outer side of the pipe sleeve (10), the pipe sleeve (10) is threadedly connected to the test tube hole (9), and the outer side surface of the test tube body (4) is an inclined surface.

4. A probe-type ultrasonic instrument according to claim 3, characterized in that: A plurality of probes (5) are fixedly arranged at the bottom of the ultrasonic main unit (2), and a number of test tube holes (9) equal to the number of the probes (5) are opened at the top of the sample fixing member (3).

5. A probe-type ultrasonic instrument according to claim 4, characterized in that: The side ends of the probes (5) are each provided with a liquid level sensor (6); the fixed block (8) comprises a mounting seat (13) and a mounting block (14); the test tube hole (9) is provided on the mounting block (14); a plurality of slide grooves (15) are provided in the mounting seat (13); the mounting block (14) is slidably arranged in the slide grooves (15); and two drive sources (16) whose number is the same as the number of the mounting blocks (14) are also provided in the mounting seat (13); the two drive sources (16) respectively control the mounting seat (13) to move up and down.

6. A probe-type ultrasonic instrument according to claim 5, characterized in that: The driving source 1 (7) comprises a linear motor, the mounting seat (13) is fixedly arranged at the output end of the linear motor, the driving source 2 (16) comprises a servo motor, a screw rod (17) is fixed at the output end of the servo motor, a screw hole (18) is formed at the bottom of the mounting block (14), and the screw rod (17) is threadedly connected to the screw hole (18).

Citation Information

Patent Citations

  • Ultrasonic interrupting instrument capable of conveniently adjusting real angle

    CN220294878U