Novel use of a peptide to improve the extracellular matrix of the skin's dermis and / or mucous membranes
A peptide enhances ECM fiber organization and density in skin and mucous membranes by increasing fibrillin-1, EMILIN-1, and collagen synthesis, addressing the limitations of existing treatments and improving skin and mucous membrane flexibility and hair anchoring.
Patent Information
- Application Number
- FR2022011001
- Authority / Receiving Office
- FR · FR
- Patent Type
- Patents
- Current Assignee / Owner
- Filing Date
- 2022-10-24
- Publication Date
- 2026-04-10
- Estimated Expiration
- 2042-10-24
AI Technical Summary
Existing cosmetic and dermatological approaches fail to effectively restore and maintain the structural integrity and functional properties of the extracellular matrix (ECM) in the skin and mucous membranes, particularly under environmental stress, by merely inhibiting proteases or increasing collagen and elastin synthesis, which does not translate into organized functional ECM fibers.
A peptide with SEQ ID No. 1 sequence, its homologs, derivatives, and salts, obtained through chemical synthesis, biotechnological production, or enzymatic hydrolysis, enhances the organization and density of ECM fibers by increasing the amount of fibrillin-1, EMILIN-1, collagen, and elastin synthesis, thereby improving skin and mucous membrane flexibility and density.
The peptide significantly increases the number of functional ECM fibers, enhancing skin and mucous membrane flexibility and density, and improves hair anchoring, without causing irritation, and is suitable for sensitive and sensitized skin types.