Apparatus, System, and Method for Soft Tissue Ablation

JP2025519373A5Pending Publication Date: 2026-06-22ALPFA MEDICAL INC
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Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
ALPFA MEDICAL INC
Filing Date
2023-06-12
Publication Date
2026-06-22

AI Technical Summary

Technical Problem

Existing soft tissue ablation techniques, such as thermal methods, often result in significant tissue damage and necrosis, while pulse-field ablation offers a tissue-selective approach but requires more effective systems and waveforms for efficient delivery.

Method used

A system and method for delivering high voltage pulse waveforms to electrodes placed near tissues for rapid and efficient ablation, utilizing a pulse generator and signal router to manage waveform delivery and electrode activation, with specific waveform characteristics including two-phase pulses and varying inter-pulse delays.

Benefits of technology

The described system enables efficient and minimally damaging soft tissue ablation, reducing collateral tissue damage and promoting faster healing, while allowing for precise control over the ablation region.

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Abstract

The systems, devices, and methods described herein relate to the generation and delivery of pulse waveforms for treatment delivery, for example, in soft tissue ablation procedures. In some embodiments, a pulse generator is configured to generate a voltage pulse train that includes a plurality of biphasic pulses, each biphasic pulse of the plurality of biphasic pulses including a positive pulse, a negative pulse, and a phase delay separating the positive pulse and the negative pulse. In some embodiments, consecutive biphasic pulses of the plurality of biphasic pulses may be separated by an inter-pulse delay such that the plurality of biphasic pulses are separated by a plurality of inter-pulse delays, the plurality of inter-pulse delays may include an increasing sequence or a decreasing sequence of inter-pulse delays.
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