Alcohol-free multifunctional hair care composition

Abstract

The present invention is directed to a clear hair care composition comprising a substituted 2-pyridinol-N-oxide material, a glycol, a nonionic surfactant, a monocarboxylic or polyprotic acid, and water or an aqueous carrier, wherein the composition has a pH of about 3.5 to about 6.0, and the composition is alcohol-free.

Description

[Technical Field]

[0001] The present invention relates to an alcohol-free multi-functional hair care composition. [Background technology]

[0002] For many years, anti-dandruff rinse-off products (shampoos, scalp treatments) have been widely used to treat dandruff and cleanse hair and scalp. However, for consumers with severe dandruff problems, such as flaking, itching, or an oily or dry scalp, using only an anti-dandruff shampoo is often insufficient. This is because the deposition or delivery of anti-dandruff actives to the scalp is limited by the use of only one product. Although anti-dandruff conditioners have been on the market for many years, these rinse-off anti-dandruff conditioners are very viscous and greasy-looking products. In fact, these products are often just regular hair conditioning products with anti-dandruff actives added. As a result, most consumers carefully apply these products to their hair, intentionally avoiding contact of the product with their scalp. This means that consumers do not receive the anti-dandruff benefits of the product. Leave-on anti-dandruff products come in various forms, such as spray tonics, lotions, and creams. The problem with these products is that, although they can provide anti-dandruff effects, they all use ethanol to dissolve oil-soluble anti-dandruff actives, leaving them opaque and sticky after application. The strong smell of ethanol, the opaqueness of the products, and the greasiness of the products when applied indicate that they are rich in chemicals, making them undesirable for daily use, and these products are not very popular on the market. The majority of consumers are looking for clear, ethanol-free products that can provide scalp benefits such as anti-dandruff and anti-itching, and that are not sticky after application and look natural. Therefore, there is a need for multifunctional hair care compositions, i.e., that can be applied to the scalp by consumers to provide scalp benefits such as anti-dandruff and anti-itching efficacy, while being clear, ethanol-free, and not sticky after application, which meets the expectations and desires of consumers.

[0003] Furthermore, consumers want to minimize the number of ingredients in a product and understand why each ingredient is needed. Many consumers want products that state on the label that the composition is free of unnecessary chemicals, especially those that are applied directly to the scalp, which may already be sensitive due to flaking and itchy dandruff symptoms. As a result, the present invention eliminates or minimizes the number of ingredients that do not primarily function to benefit the consumer, such as preservatives, stabilizers, or solvents. Summary of the Invention [Problem to be solved by the invention]

[0004] Therefore, there is a continuing need for leave-ons that not only provide scalp benefits such as anti-dandruff and anti-itch benefits, but are also ethanol-free, clear, non-sticky after application, and formulated with natural and multifunctional ingredients. [Means for solving the problem]

[0005] The present invention is directed to a clear hair care composition comprising a substituted 2-pyridinol-N-oxide material, a glycol, a nonionic surfactant, a monocarboxylic or polyprotic acid, and water or an aqueous carrier, wherein the composition has a pH of about 3.5 to about 6.0, and the composition is alcohol-free. DETAILED DESCRIPTION OF THE INVENTION

[0006] While the specification concludes with claims particularly pointing out and distinctly claiming the invention, it is believed the present invention will be better understood from the following description.

[0007] As used herein, "comprising" means that other steps and other ingredients that do not affect the end result may be added. This term encompasses the terms "consisting of" and "consisting essentially of." As used herein, "consisting essentially of" means that a composition or component may include additional ingredients, but only if the additional ingredients do not materially alter the basic and novel characteristics of the claimed composition or method.

[0008] All percentages, parts, and ratios are based on the total weight of the compositions of the present invention unless otherwise specified. All such weights relating to listed ingredients are based on the active level and, therefore, do not include carriers or by-products that may be included in commercially available materials. Unless otherwise specified, all measurements are understood to be made at ambient conditions, where "ambient conditions" means conditions at about 25°C, under about 1 atmosphere, and at about 50% relative humidity (RH). All numerical ranges are inclusive of smaller ranges, and the stated upper and lower range limits are combinable to create additional ranges not expressly stated.

[0009] As used herein, "mixture" is meant to include the simple combination of materials and any compounds that may result from such a combination.

[0010] The terms "molecular weight" or "M.Wt." as used herein, unless otherwise specified, refer to weight average molecular weight. "QS" means quantity sufficient to make 100%.

[0011] "Applying" or "application" as used in reference to a composition means applying or spreading a composition of the present invention onto keratinous tissue, such as hair.

[0012] "Dermatologically acceptable" means that the composition or components described are suitable for use in contact with human skin tissue without undue toxicity, incompatibility, instability, allergic response, etc.

[0013] By "safe and effective amount" is meant an amount of a compound or composition sufficient to significantly induce a beneficial effect.

[0014] "Rinse-off" with respect to a composition means a composition that is intended to be applied to the keratinous substrate and subsequently removed by washing, rinsing, or wiping within minutes of application. These "rinse-off" compositions should be distinguished from "leave-on" compositions that are applied and intended to be left on the keratinous tissue for a longer period of time.

[0015] "Leave-on" in reference to a composition refers to a composition intended to be applied and left on the keratinous tissue. These leave-on compositions should be distinguished from compositions that are applied to hair and subsequently removed (within minutes) by either washing, rinsing, or wiping. Leave-on compositions exclude rinse-off applications such as shampoos, rinse-off conditioners, facial cleansers, hand detergents, body washes, or personal cleansers. Leave-on compositions may be substantially free of cleansing or detersive surfactants. For example, a "leave-on composition" may be left on the keratinous tissue for at least 5 minutes. For example, a leave-on composition may contain less than 1% detersive surfactant, less than 0.5% detersive surfactant, or 0% detersive surfactant. However, the composition may contain emulsifiers, dispersants, or other processing surfactants that are not intended to provide any significant cleansing benefit when topically applied to hair.

[0016] By "soluble" is meant that at least about 0.1 g of solute will dissolve in 100 mL of solvent at 25° C. and 1 atm pressure.

[0017] As used herein, "hair" means mammalian hair, particularly hair on the human head and scalp, including scalp hair, facial hair, and body hair.

[0018] "Cosmetically acceptable," as used herein, means that the composition, formulation, or components described are suitable for use in contact with human keratinous tissue without undue toxicity, incompatibility, instability, allergic reaction, etc. All compositions described herein intended for direct application to keratinous tissue are limited to being cosmetically acceptable.

[0019] As used herein, "derivatives" include, but are not limited to, amide, ether, ester, amino, carboxyl, acetyl, acid, salt, and / or alcohol derivatives of a given compound.

[0020] As used herein, "polymer" refers to a chemical substance formed from the polymerization of two or more monomers. As used herein, the term "polymer" is intended to include all materials made by the polymerization of monomers, as well as natural polymers. A polymer made from only one type of monomer is called a homopolymer. A polymer made from two or more types of different monomers is called a copolymer. The distribution of different monomers can be calculated statistically or block by block, and both possibilities are suitable for the present invention. Unless otherwise specified, the term "polymer" as used herein includes all types of polymers, including homopolymers and copolymers.

[0021] Hair care composition The hair care compositions of the present invention provide a combination of multifunctional ingredients that can provide multiple benefits, including anti-dandruff, anti-itch, soothing, fragrance, preservatives, a non-greasy feel, and dry conditioning, while containing nine or fewer ingredients. The product's appearance is clear and in spray form, but it can be somewhere between a cream and a lotion and may even be slightly translucent in appearance. Having presented a solution to the problem of providing a hair care composition that provides the numerous benefits described without requiring a large number of ingredients, it is further understood that a single ingredient can perform multiple functions. The present invention is directed to formulating compositions containing natural ingredients preferred by consumers. For example, the nonionic surfactant polyethoxylated sorbitan is naturally derived from vegetable oils and fats, and formulators have free rein to select it as an emulsifier in a non-alcohol-containing vehicle.

[0022] Anti-dandruff actives Piroctone and piroctone salts, such as piroctone olamine, are known to provide anti-dandruff benefits. However, piroctone olamine is often supplied as a crystalline powder and is also known to have very limited solubility in water. This means that it is a challenge to ensure the solubilization of anti-dandruff actives in as simple a material combination as possible.

[0023] The present inventors have found that certain solid organic compounds, such as piroctone and / or its salts, tend to crystallize under the following conditions: - when the amount of solid organic compounds in the composition is increased, in particular when it is greater than 0.2%, and / or when the composition has a pH of about 3.5 to about 6.

[0024] Piroctone olamine in leave-on formulas is typically solubilized with an emollient oil, such as alcohol (e.g., ethanol) or triethylhexanoin, or a high concentration (>30%) of octyldodecyl myristate. The oil is typically emulsified by suspending a polymer (e.g., acrylate), resulting in an opaque product that is very viscous and feels sticky after application. In contrast, the present invention does not use emollient oils, ethanol, or adhesive polymers; instead, it uses a mixture of glycols and nonionic surfactants in a specific ratio relative to piroctone olamine to achieve the desired pH range for better function and adhesion to the scalp. This provides anti-dandruff efficacy and a non-greasy hair feel without using too much glycol.

[0025] In the present invention, the anti-dandruff active can be a substituted 2-pyridinol-N-oxide material, such as piroctone olamine or ciclopirox olamine. Piroctone olamine and ciclopirox olamine are salts of piroctone and ciclopirox with monoethanolamine, respectively. In compositions having an acidic pH, they are protonated to form piroctone and ciclopirox, respectively. In the present invention, the composition can have an acidic pH, a pH of about 2 to about 6, a pH of about 3.5 to about 6, or a pH of about 3.5 to about 5.

[0026] The present invention may also include one or more soluble scalp health actives, which may be one or a mixture of materials selected from the group consisting of azoles such as climbazole, ketoconazole, itraconazole, econazole, and elubiol; hydroxypyridones such as piroctone olamine, ciclopirox, rilopirox, and MEA-hydroxyoctyloxypyridinone; strobilurins such as azoxystrobin; and metal chelators such as 1,10-phenanthroline.

[0027] The azole-soluble scalp health active may be an imidazole selected from the group consisting of benzimidazole, benzothiazole, bifonazole, butaconazole nitrate, climbazole, clotrimazole, cloconazole, eberconazole, econazole, elubiol, fenticonazole, fluconazole, flutimazole, isoconazole, ketoconazole, lanoconazole, metronidazole, miconazole, neticonazole, omoconazole, oxiconazole nitrate, sertaconazole, sulconazole nitrate, tioconazole, thiazole, and mixtures thereof, or the azole antibacterial is a triazole selected from the group consisting of terconazole, itraconazole, and mixtures thereof. The azole-soluble scalp health active may be ketoconazole. The only soluble scalp health active may be ketoconazole.

[0028] These anti-dandruff and scalp health active compounds are not soluble in typical solvents, such as water or aqueous mixtures, including water containing high concentrations of glycerin. They typically require either high concentrations (greater than 5% or even 10%) of emollient oils, such as triethylhexanoin or octyldodecyl myristate, or high concentrations (greater than 50%) of alcohols, such as ethanol. The former (oils) are known to cause a negative oily feel on the scalp and hair, while the latter (alcohols) are known to scare many consumers away from applying them to scalps already sensitive to dandruff. The present invention solubilizes these anti-dandruff actives through a combination of a surfactant (primarily required for hair conditioning) and a specific acid (primarily required for pH adjustment). Nothing other than these two ingredients is needed to formulate these anti-dandruff and scalp health actives into a soluble form in a liquid.

[0029] Any anti-dandruff or other scalp active may be present in the composition in an amount of from about 0.01% to about 3% by weight of the composition. In the present invention, the anti-dandruff or other scalp active may be from about 0.1 to 2%, or from about 0.5 to 1% of the anti-dandruff or other scalp active.

[0030] Nonionic surfactants The hair care compositions of the present invention may contain a nonionic surfactant. Nonionic surfactants are typically compounds formed by condensation of an alkylene oxide group (which is hydrophilic in nature) with an organic hydrophobic compound, which may be aliphatic or alkylaromatic in nature, but may include other surfactants without charged groups. In the present invention, the nonionic surfactant may have an HLB value of 10 to 15. Examples of classes of nonionic surfactants are as follows: Alkylphenol ethoxylates. Polyethylene oxide condensates of alkylphenols, such as the condensation products of alkylphenols having alkyl groups containing about 6 to 12 carbon atoms, in either a linear or branched configuration, with ethylene oxide, the ethylene oxide being present in an amount equivalent to 10 to 60 moles of ethylene oxide per mole of alkylphenol. The alkyl substituents in such compounds can be derived, for example, from polymerized propylene, diisobutylene, octane, or nonane. b. Polyethylene glycol / polypropylene glycol block copolymers, derived from the condensation of ethylene oxide with the product obtained from the reaction of propylene oxide with an ethylenediamine product, can vary in composition depending on the desired balance between hydrophobic and hydrophilic components. For example, compounds containing about 40% to about 80% by weight of polyoxyethylene and having a molecular weight of about 5,000 to about 11,000, obtained from the reaction of ethylene oxide groups with a hydrophobic base consisting of the reaction product of ethylenediamine with excess propylene oxide, the base having a molecular weight of about 2,500 to 3,000, are satisfactory. c. Fatty alcohol and fatty acid ethoxylates. Condensation products of aliphatic alcohols having 8 to 18 carbon atoms in either a linear or branched chain arrangement with ethylene oxide, such as coconut alcohol-ethylene oxide condensates having 10 to 30 moles of ethylene oxide per mole of coconut alcohol, where the coconut alcohol fraction has 10 to 14 carbon atoms. Other ethylene oxide condensation products are ethoxylated fatty acid esters of polyhydric alcohols (e.g., Tween 20 - polyoxyethylene (20) sorbitan monolaurate). d. Long-chain tertiary amine oxides, which correspond to the general formula: R1 R2 R3 N→O wherein R1 contains an alkyl, alkenyl, or monohydroxyalkyl radical of about 8 to about 18 carbon atoms, 0 to about 10 ethylene oxide moieties, and 0 to 1 glyceryl moiety; and R2 and R3 contain 1 to about 3 carbon atoms and 0 to about 1 hydroxy group, such as, for example, methyl, ethyl, propyl, hydroxyethyl, or hydroxypropyl radicals. The arrow in the formula is a conventional representation of a semipolar bond. Examples of amine oxides suitable for use in the present invention include dimethyldodecylamine oxide, oleyldi(2-hydroxyethyl)amine oxide, dimethyloctylamine oxide, dimethyldecylamine oxide, dimethyltetradecylamine oxide, 3,6,9-trioxaheptadecyldiethylamine oxide, di(2-hydroxyethyl)tetradecylamine oxide, 2-dodecoxyethyldimethylamine oxide, 3-dodecoxy-2-hydroxypropyldi(3-hydroxypropyl)amine oxide, and dimethylhexadecylamine oxide. e. Long-chain tertiary phosphine oxides, which correspond to the general formula: RR'R''P→O where R is an alkyl, alkenyl, or monohydroxyalkyl radical with a chain length ranging from 8 to 18 carbon atoms, containing 0 to about 10 ethylene oxide moieties, and 0 to 1 glyceryl moiety, and R' and R" are each alkyl or monohydroxyalkyl groups containing 1 to 3 carbon atoms. The arrow in the formula is a conventional representation of a semipolar bond. Examples of suitable phosphine oxides are dodecyldimethylphosphine oxide, tetradecylmethylethylphosphine oxide, 3,6,9-trioxaoctadecyldimethylphosphine oxide, cetyldimethylphosphine oxide, 3-dodecoxy-2-hydroxypropyldi(2-hydroxyethyl)phosphine oxide, stearyldimethylphosphine oxide, cetylethylpropylphosphine oxide, oleyldiethylphosphine oxide, dodecyldiethylphosphine oxide, tetradecyldiethylphosphine oxide, dodecyldipropylphosphine oxide, dodecyldi(hydroxymethyl)phosphine oxide, dodecyldi(2-hydroxyethyl)phosphine oxide, tetradecylmethyl-2-hydroxypropylphosphine oxide, oleyldimethylphosphine oxide, 2-hydroxydodecyldimethylphosphine oxide. f. Long-Chain Dialkyl Sulfoxides. Long-chain dialkyl sulfoxides containing one short-chain alkyl or hydroxyalkyl radical (usually methyl) of 1 to about 3 carbon atoms and one hydrophobic long chain comprising an alkyl, alkenyl, hydroxyalkyl, or ketoalkyl radical containing about 8 to about 20 carbon atoms, 0 to about 10 ethylene oxide moieties, and 0 to 1 glyceryl moiety. Examples include octadecyl methyl sulfoxide, 2-ketotridecyl methyl sulfoxide, 3,6,9-trioxaoctadecyl 2-hydroxyethyl sulfoxide, dodecyl methyl sulfoxide, oleyl 3-hydroxypropyl sulfoxide, tetradecyl methyl sulfoxide, 3-methoxytridecyl methyl sulfoxide, 3-hydroxytridecyl methyl sulfoxide, and 3-hydroxy-4-dodecoxybutyl methyl sulfoxide. g. Alkyl polysaccharide (APS) surfactants, such as alkyl polyglycosides. Such surfactants are APS surfactants having a hydrophobic group having about 6 to about 30 carbon atoms and a polysaccharide (e.g., polyglycoside) as the hydrophilic group. Optionally, a polyalkylene oxide group can be present connecting the hydrophobic and hydrophilic portions. The alkyl group (i.e., the hydrophobic portion) can be saturated or unsaturated, branched or unbranched, and unsubstituted or substituted (e.g., with hydroxy or cyclic rings). h. Polyethylene glycol (PEG) glyceryl fatty esters such as R(O)OCH2CH(OH)CH2(OCH2CH2)nOH, where n is from about 5 to about 200, and can be from about 20 to about 100, and R is an aliphatic hydrocarbyl having from about 8 to about 20 carbon atoms.

[0031] The compositions of the present invention may include Tween 80-polyoxyethylene (20) sorbitan monolaurate, may include about 1% to about 15% of a nonionic surfactant, may include 3-10% of a nonionic surfactant, or may include 5-10% of a nonionic surfactant.

[0032] Monocarboxylic and polyprotic acids The monocarboxylic acid may be an alpha-hydroxy acid (AHA), a beta-hydroxy acid (BHA), or a polyhydroxy acid (PHA). The BHA may be salicylic acid, reducing or eliminating the need for added preservatives. In the present invention, the acid may be lactic acid or glycolic acid (both alpha-hydroxy acids) instead of salicylic acid. The polyhydroxy acid used may be lactobionic acid or gluconolactone. Other acids that may be used are those that have a net charge of -1 as their predominant species at the final pH of the composition, such as glutamic acid or aspartic acid, but are likely to require a preservative in the composition. Polyprotic acids, such as maleic acid, oxalic acid, citric acid, EDTA, malic acid, and tartaric acid, may be included in the compositions of the present invention to adjust the pH of the leave-on composition. Combinations or mixtures of acids may be used in the present invention. The present invention may contain about 0.02% to about 0.2% of a polyprotonic acid, ie, citric acid, or about 0.05% to about 0.1% of an acid.

[0033] Aqueous Carrier The hair care compositions of the present invention comprise an aqueous carrier, the level and type of which is selected according to compatibility with the other components and other desired properties of the product.

[0034] In the present invention, the aqueous carrier may be substantially water. Deionized water may be used. Water from natural sources containing mineral cations may also be used, depending on the desired properties of the product. Generally, the compositions of the present invention contain about 20% to about 99% water, and may be about 30% to about 95% water, or may be about 80% to about 95% water.

[0035] glycol The hair care composition of the present invention may contain a dermatologically acceptable solvent. In the present invention, the carrier may include water, as well as a solution or mixture of water with a lower alkyl alcohol and / or a polyhydric alcohol. Examples of lower alkyl alcohols are monohydric alcohols having 1 to 6 carbon atoms, such as ethanol, methanol, propanol, isopropanol, butanol, pentanol, and hexanol. Examples of polyhydric alcohols include glycols such as dipropylene glycol, propylene glycol, and butylene glycol, 1,4-butanediol, 3-allyloxy-1,2-propanediol, 1,2-hexanediol, 1,6-hexanediol, 1,3-butanediol, 1,3-propanediol, 2,2'-thiodiethanol, glycerin, and other diols.

[0036] Other non-limiting examples of organic solvents include polyglycols such as polypropylene glycol, polyethylene glycol, mixtures of butylene glycol, polypropylene glycol, polyethylene glycol and ethers such as dipropylene glycol n-butyl ether, sugars, and sugar derivatives.

[0037] The composition of the present invention may contain propylene glycol, and may contain from about 1% to about 10%, or from about 1% to about 5%, or from about 2% to about 3% of a solvent.

[0038] Water-soluble polymers The hair care composition of the present invention may contain a water-soluble polymer. To adjust the viscosity of the composition, a hydrophobically modified polymer may be used while the total concentration of the lamellar gel phase is low. The hydrophobically modified water-soluble polymer may have a backbone of natural origin, such as, but not limited to, xanthan gum, cellulose, starch, guar, gellan, and combinations thereof. The water-soluble polymer may have a cationic charge. In the present invention, the water-soluble polymer may be polyquaternium-10, such as UCARE Extreme Polymer supplied by Dow Inc., or cetyl hydroxyethyl cellulose, such as Polysurf 67 CS or Natrosol 330 PLUS CS, both supplied by Ashland. The polymer may be one that can help restore the hydrophobicity of the hair surface due to its own higher hydrophobicity.

[0039] The composition of the present invention may contain about 0.01% to about 0.5%, or may contain about 0.05% to about 0.25% of a water-soluble polymer.

[0040] Active substances for scalp health In the present invention, scalp health actives can be added to provide scalp benefits. This range of ingredients varies and provides a wide range of benefits, including anti-dandruff, anti-fungal, anti-bacterial, moisturizing, barrier improvement, as well as antioxidant, anti-itch, and sensual effects. Such skin health actives and scalp care actives include, but are not limited to, zinc pyrithione, climbazole, selenium sulfide, vitamins E and F, salicylic acid, glycol, glycolic acid, PCA, PEG, erythritol, glycerin, lactate, hyaluronate, allantoin and other ureas, betaine, sorbitol, glutamate, xylitol, menthol, menthyl lactate, isocyclomone, benzyl alcohol, and natural extracts / oils, including peppermint, spearmint, argan, jojoba, and aloe.

[0041] Optional Ingredients The compositions of the present invention may also contain suitable optional ingredients as desired, for example, the compositions may optionally contain other active or inactive ingredients.

[0042] The compositions may include other common hair ingredients, such as other anti-dandruff actives, minoxidil, conditioning agents, and other suitable materials. The CTFA Cosmetic Ingredient Handbook, Tenth Edition (published by the Cosmetic, Toiletry, and Fragrance Association, Inc., Washington, DC) (2004) (hereinafter "CTFA") describes a variety of non-limiting materials that may be added to the compositions herein. Examples of these ingredient classes include, but are not limited to, abrasives; absorbents; aesthetic components such as fragrances, pigments, colorants / dyes, essential oils, skin sensates, astringents (e.g., clove oil, menthol, camphor, eucalyptus oil, eugenol, menthyl lactate, witch hazel distillate); anti-acne agents; anti-caking agents; anti-foaming agents; antimicrobial agents (e.g., iodopropyl butylcarbamate); antioxidants; niacinamide; binders; biological additives; buffers; bulking agents; chelating agents; chemical additives; dyes; cosmetic astringents; cosmetic biocides; denaturing agents; medicinal astringents; topical analgesics; film-forming agents or materials, such as polymers to aid in the film-forming properties and substantivity of the composition (e.g., copolymers of eicosene and vinylpyrrolidone); opacifying agents; pH adjusters; propellants; reducing agents; sequestering agents; rheology modifiers; hair conditioning agents; and surfactants.

[0043] acid The hair care compositions of the present invention may contain an acid, which can be used to control the pH of the composition within the desired range (3.5 to 6), as the presence of piroctone olamine may otherwise cause the pH to rise above 7.

[0044] fragrance The composition of the present invention may contain a fragrance or a combination of fragrances. Some fragrances may contain multiple fragrance ingredients. In particular, fragrances may contain hinokitiol, phenoxyethanol, and L-menthol. The composition may contain fragrances at the concentration required to create the desired fragrance characteristics and intensity, but not at a concentration high enough that any of the ingredients acts as a preservative for the composition.

[0045] Additional ingredients The compositions of the present invention may contain other additional ingredients, which can be selected by one skilled in the art depending on the desired properties of the final product and which are suitable for making the composition more cosmetically or aesthetically acceptable or for providing additional usage benefits to the composition. Such other additional ingredients are generally used individually at a concentration of from about 0.001% to about 10% by weight of the composition, and may amount to up to about 5% by weight of the composition.

[0046] A wide variety of other additional ingredients can be incorporated into the compositions of the present invention, including other conditioning agents (such as hydrolyzed collagen under the trade name Peptein 2000 available from Hormel, vitamin E under the trade name Emix-d available from Eisai, panthenol available from Roche, pantothenyl ethyl ether available from Roche, hydrolyzed keratin, proteins, plant extracts, and nutrients), preservatives (such as benzyl alcohol, methylparaben, propylparaben, and imidazolidinyl urea), pH adjusters (such as citric acid, sodium citrate, succinic acid, phosphoric acid, sodium hydroxide, sodium carbonate), general salts (such as potassium acetate and sodium chloride), colorants (such as any of the FD&C or D&C dyes), fragrances, and sequestering agents (such as disodium ethylenediaminetetraacetate), as well as ultraviolet and infrared screening and absorbing agents (such as octyl salicylate).

[0047] In the present invention, the composition of the present invention may not contain a preservative.In the present invention, the composition may not contain a preservative compound such as phenoxyethanol, benzyl alcohol, methylparaben, ethylparaben, and / or propylparaben.Phenoxyethanol may be used as a fragrance at a concentration of up to 0.1% by weight of the composition, but may not be used as a preservative at a concentration of at least 0.25% by weight of the composition.

[0048] In the present invention, the composition may be free of liquid oily compounds having an AlogP≧5.5.

[0049] Product form The compositions of the present invention may be in the form of leave-on or rinse-off products and may be formulated in a wide variety of product forms, including, but not limited to, creams, gels, emulsions, mousses, and sprays.

[0050] The compositions of the present invention are particularly suitable for hair leave-on. Such compositions can be used in the following steps: (i) applying an effective amount of the composition to the scalp and hair roots for scalp benefits after shampooing the hair and / or after using a rinse-off conditioner; (ii) The hair is then either not rinsed or rinsed.

[0051] translucency The hair care compositions of the present invention may be transparent or translucent. The translucency of the composition may be preferred by consumers and may signal application to the scalp to provide anti-dandruff benefits.

[0052] The compositions of the present invention may have a viscosity of from about 0.01 Pa·s to about 10 Pa·s, and in some cases from about 5 Pa·s to about 10 Pa·s. Compositions with lower viscosities are more likely to be applied to the scalp by a consumer and, therefore, are more likely to provide anti-dandruff benefits.

[0053] Consumers may desire compositions of the present invention that contain minimal concentrations of ingredients. The compositions may be formulated without polymeric thickeners or suspending agents, such as carbomer, EGDS, or thixotropic acid. The compositions may be composed of 11 or fewer ingredients, 10 or fewer ingredients, 9 or fewer ingredients, 8 or fewer ingredients, 7 or fewer ingredients, or 6 or fewer ingredients. It is understood that the fragrance may be formed from one or more ingredients.

[0054] Formulations and Examples The following are non-limiting examples of the present invention, which are provided for illustrative purposes only and should not be construed as limiting the present invention, many variations of which are possible without departing from the spirit and scope of the present invention, as will be recognized by those skilled in the art.

[0055] Formulation preparation and treatment protocol: Preparation of leave-on treatment composition: The leave-on treatment composition is prepared by adding piroctone olamine and, if desired, glycol and fragrance to a nonionic surfactant / water carrier and stirring until completely dissolved. The pH of the solution is adjusted to a final pH of 4.0-6.0 using a citric acid solution. Polymer (if desired) is then added, if desired, and the solution is mixed using a high-speed mixer at 1800-2300 rpm for 2-5 minutes until a uniform composition is obtained.

[0056] Leave-on Hair Treatment Protocol: A 0.20 g amount of each composition of Examples I-IV is spread with a syringe onto a separate natural virgin brown hair switch weighing 2.0 g (a dose of 0.10 g of solution per gram of hair). The hair is allowed to air dry and then rated for sticky / coated feel by each panel.

[0057] Evaluation method The hair switches treated with the leave-on treatment compositions are evaluated using the following methodology.

[0058] Method for rating stickiness using hair switches: The treated hair switches are kept at room temperature and laboratory conditions (32-35°C, 50% RH) for 2 hours, and then 10 trained raters are asked to rate each hair switch in terms of the sticky feel of the hair based on a 5-point scale (5 being the highest score (very sticky) and 1 being the lowest score (not sticky)).

[0059] Phase stability: Samples are stored in glass jars at room temperature (32-35°C, 50% RH). Visible phase separation is recorded after one month. The same samples are observed under a microscope (Keyence Digital Microscope VHX-7000 series) equipped with cross-polarizing filters for the presence of piroctone olamine crystals. S = stable, U = unstable.

[0060] Clarity: The clarity of the samples is scored within one day of sample preparation. Clarity scores are 1 - Opaque, 3 - Semi-opaque and 5 - Transparent, with the formulation scored per panel. [Example]

[0061] The following are non-limiting examples of the present invention. The following examples further describe and demonstrate embodiments within the scope of the present invention. The examples are provided for illustrative purposes only and should not be construed as limiting the present invention, many variations of which are possible without departing from the spirit and scope of the present invention. Where applicable, components are identified by chemical name or CTFA name, or otherwise defined below.

[0062] [Table 1] 1 Octopirox, Clariant 2 Dow 3 Merck 4 Tween 80, Croda 5 Labbeemint, Inc. 6 Sigma Aldrich 7 Jungbunzlauer Austria 8 Supplied by Ineos Maastricht BV (Maastricht NL) 9 Cargill

[0063] Results: Formulation Examples 1-4 demonstrate clear, stable, non-sticky formulations at pH 5.5-5.8, while Example 5 is unstable due to high pH crystal formation as demonstrated one day after formulation preparation. Examples 6 and 7 are unstable due to low solvent glycol and the absence of Tween 80 to form a microemulsion, respectively. Example 8 is translucent due to the addition of xanthan gum, whereas Examples 1-4 are clear.

[0064] combination A. A clear hair care composition comprising a substituted 2-pyridinol-N-oxide material, a glycol, a nonionic surfactant, a monocarboxylic or polyprotic acid, and water or an aqueous carrier, wherein the composition has a pH of about 3.5 to about 6.0, and the composition is alcohol-free. B. The clear hair care composition of paragraph A, wherein the nonionic surfactant has an HLB value of 10 to 15. C. The clear hair care composition of paragraphs A-B, comprising from about 1% to about 10% of a glycol selected from the group consisting of dipropylene glycol, propylene glycol, butylene glycol, 1,4-butanediol, 3-allyloxy-1,2-propanediol, 1,2-hexanediol, 1,6-hexanediol, 1,3-butanediol, 1,3-propanediol, 2,2'-thiodiethanol, or glycerin. D. The clear hair care composition of paragraphs A-C, wherein the glycol is propylene glycol. E. The clear hair care composition of paragraphs A-D, comprising from about 1% to about 15% of a nonionic surfactant selected from the group consisting of alkylphenol ethoxylates, polyethylene glycol / polypropylene glycol block copolymers, fatty alcohol and fatty acid ethoxylates, long chain tertiary amine oxides, long chain tertiary phosphine oxides, long chain dialkyl sulfoxides, alkyl polysaccharides or polyethylene glycol glyceryl fatty esters, and mixtures thereof. F. The clear hair care composition of paragraphs A-E, wherein the nonionic surfactant is Tween 80-polyoxyethylene (20) sorbitan monolaurate. G. The clear hair care composition of paragraphs A-F, comprising from about 0.02% to about 0.2% of a monocarboxylic acid selected from the group consisting of alpha-hydroxy acids (AHA), beta-hydroxy acids (BHA), or polyhydroxy acids (PHA), and mixtures thereof. H. The clear hair care composition of paragraphs A-G, wherein the polyprotonic acid is selected from the group consisting of maleic acid, oxalic acid, citric acid, EDTA, malic acid, or tartaric acid, and mixtures thereof. I. The clear hair care composition of paragraphs AH, wherein the polyprotonic acid is citric acid. J. The clear hair care composition of paragraphs AI, further comprising from about 0.01% to about 0.5% of a water-soluble polymer. K. The clear hair care composition of paragraphs AJ, wherein the water-soluble polymer has a backbone of natural origin selected from the group consisting of cellulose, starch, guar, or gellan, and mixtures thereof. L. The clear hair care composition of paragraphs A-K, wherein the water-soluble polymer is selected from the group consisting of polyquaternium-10 or cetyl hydroxyethyl cellulose, and mixtures thereof. M. The clear hair care composition of paragraphs A-L, further comprising a scalp health active. N. The clear hair care composition of paragraphs A-M, wherein the composition is non-sticky and stable. O. The clear hair care composition of paragraphs A-N, wherein the composition is free of anionic surfactants. P. The clear hair care composition of paragraphs A-O, wherein the composition consists of 9 or fewer ingredients. Q. a. Water, b. Piroctone olamine, c. propylene glycol; d. Niacinamide, e. Tween-80 and f. Mosamin oil; g. Panthenol, h. citric acid, i. benzyl alcohol. R. a. Water, b. Piroctone olamine, c. propylene glycol; d. Niacinamide, e. Tween-80 and f. Mosamin oil; g. Panthenol, h. Citric acid and i. benzyl alcohol; j. The clear hair care composition of paragraphs A-Q, optionally consisting of a fragrance.

[0065] It will be understood that other modifications of the present disclosure within the skill of those skilled in the art of hair care formulations can be made without departing from the spirit and scope of the present invention. All parts, percentages, and ratios herein are by weight unless otherwise specified. Some components may be provided by the supplier as a dilute solution. The concentrations listed represent the weight percent of actives unless otherwise specified. Also, fragrance and / or preservative concentrations may be included in the following examples.

[0066] The dimensions and values ​​disclosed herein should not be understood as being strictly limited to the exact numerical values ​​recited. Instead, unless otherwise specified, each such dimension is intended to mean both the recited value and a functionally equivalent range surrounding that value. For example, a dimension disclosed as "40 mm" is intended to mean "about 40 mm."

[0067] All documents cited herein, including cross-referenced or related patents or applications, are incorporated herein by reference in their entirety, unless expressly excluded or otherwise limited. The citation of any document shall not be deemed to be prior art to any invention disclosed or claimed herein, or that it alone, or in combination with any other reference or references, teaches, suggests, or discloses such invention. Furthermore, to the extent that any meaning or definition of a term in this document conflicts with any meaning or definition of the same term in a document incorporated by reference, the meaning or definition assigned to that term in this document shall control.

[0068] While particular embodiments of the present invention have been illustrated and described, it would be obvious to those skilled in the art that various other changes and modifications can be made without departing from the spirit and scope of the invention. It is therefore intended to cover in the appended claims all such changes and modifications that are within the scope of this invention.

Claims

1. a) a substituted 2-pyridinol-N-oxide material; b) glycol; c) a nonionic surfactant; and d) a monocarboxylic or polyprotic acid; and e) water or an aqueous carrier, A clear hair care composition, wherein the composition has a pH of 3.5 to 6.0, and the composition is alcohol-free.

2. 10. The clear hair care composition of claim 1, wherein the nonionic surfactant has an HLB value of 10-15.

3. 3. The clear hair care composition of any one of claims 1 to 2, comprising 1% to 10% of a glycol selected from the group consisting of dipropylene glycol, propylene glycol, butylene glycol, 1,4-butanediol, 3-allyloxy-1,2-propanediol, 1,2-hexanediol, 1,6-hexanediol, 1,3-butanediol, 1,3-propanediol, 2,2'-thiodiethanol or glycerin, preferably said glycol is propylene glycol.

4. 4. The clear hair care composition of any one of claims 1 to 3, comprising 1% to 15% of a nonionic surfactant selected from the group consisting of alkylphenol ethoxylates, polyethylene glycol / polypropylene glycol block copolymers, fatty alcohol and fatty acid ethoxylates, long chain tertiary amine oxides, long chain tertiary phosphine oxides, long chain dialkyl sulfoxides, alkyl polysaccharides or polyethylene glycol glyceryl fatty esters and mixtures thereof, preferably wherein the nonionic surfactant is Tween 80-polyoxyethylene (20) sorbitan monolaurate.

5. 5. The clear hair care composition of any one of claims 1 to 4, comprising 0.02% to 0.2% of a monocarboxylic acid selected from the group consisting of alpha hydroxy acids (AHA), beta hydroxy acids (BHA), or polyhydroxy acids (PHA), and mixtures thereof.

6. 6. The transparent hair care composition of any one of claims 1 to 5, wherein the polyprotonic acid is selected from the group consisting of maleic acid, oxalic acid, citric acid, EDTA, malic acid or tartaric acid and mixtures thereof, preferably the polyprotonic acid is citric acid.

7. The clear hair care composition of any one of claims 1 to 6, further comprising from 0.01% to 0.5% of a water-soluble polymer.

8. 8. The transparent hair care composition of claim 1, wherein the water-soluble polymer has a backbone of natural origin selected from the group consisting of cellulose, starch, guar, or gellan, and mixtures thereof.

9. The transparent hair care composition of any one of claims 1 to 8, wherein the water-soluble polymer is selected from the group consisting of polyquaternium-10 or cetyl hydroxyethyl cellulose and mixtures thereof.

10. 10. The clear hair care composition of any one of claims 1 to 9, further comprising a scalp health active.

11. The transparent hair care composition of any one of claims 1 to 10, wherein the composition is non-sticky and stable.

12. The clear hair care composition of any one of claims 1 to 11, wherein the composition is free of anionic surfactants.

13. The clear hair care composition of any one of claims 1 to 12, wherein the composition consists of no more than 9 ingredients.

14. a. Water; b. Piroctone olamine, c. propylene glycol; d. niacinamide, and e. Tween-80; f. Mosamin oil; g. panthenol, h. citric acid, i. benzyl alcohol.

15. a. Water; b. Piroctone olamine, c. propylene glycol; d. niacinamide, and e. Tween-80; f. Mosamin oil; g. panthenol, h. Citric acid and i. benzyl alcohol, j. The clear hair care composition of any one of claims 1 to 14, optionally consisting of a fragrance.

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