Systems and methods for measuring the concentration of analytes

A hybrid III-V/IV semiconductor SoC addresses scalability and complexity issues in spectroscopic analyte measurement, enabling accurate, real-time monitoring of analytes in wearable devices through scattering corrections and multivariate regression.

KR103013780B1Active Publication Date: 2026-09-02브로리스센서테크놀로지유에이비
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Patent Information

Application Number
KR1020227022133
Authority / Receiving Office
KR · KR
Patent Type
Patents
Current Assignee / Owner
Priority Date
2019-12-06
Filing Date
2020-12-03
Publication Date
2026-09-02
Estimated Expiration
2040-12-03

AI Technical Summary

Technical Problem

Existing spectroscopic non-invasive analyte measurement techniques, such as near-infrared spectroscopy, are cumbersome and impractical for consumer electronics due to their large and complex structures, while hybrid III-V/IV semiconductor photonic systems face scalability issues with high absorption and optical confinement, limiting their application in consumer electronics and wearable devices.

Method used

A hybrid III-V/IV semiconductor photonic system-on-a-chip (SoC) with integrated emission wavelength tuning and absolute wavelength correction is used for non-invasive analyte measurement, employing optical communication with biological materials to correct for complex biological signals, utilizing scattering corrections and multivariate regression to derive accurate analyte concentrations.

Benefits of technology

Enables accurate, real-time monitoring of analytes like glucose and lactate in wearable devices by correcting for tissue scattering and absorption, providing precise concentration levels despite complex biological environments.

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Abstract

Techniques for acquiring and processing data in combination with a photonic sensor SoC (system-on-a-chip) (1) to provide real-time corrected concentration levels of an analyte (e.g., a constituent molecule within a biological material) are described. The raw signal (1300) to be analyzed is collected by the sensor chip (1) via diffuse reflectance or transmittance. Determination of the analyte concentration is based, in part, on Beer-Lambert principles and is facilitated by applying scattering correction (2240) to the raw signal prior to decomposition and analysis of the raw signal (1300).
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