PREVENTION OR TREATMENT OF GOUT OR URIC ACID DISEASE

MA41431AActive Publication Date: 2017-12-06SHANTON PHARMA PTE LTD
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Patent Information

Application Number
MA41431
Authority / Receiving Office
MA · MA
Patent Type
Applications
Current Assignee / Owner
Priority Date
2015-04-30
Filing Date
2016-01-28
Publication Date
2017-12-06
Estimated Expiration
2036-01-28

AI Technical Summary

Technical Problem

Current treatments for gout and hyperuricemia are limited in efficacy and are associated with adverse side effects, and there is a need for new agents that can effectively reduce uric acid levels and alleviate inflammation.

Method used

A class of xanthine compounds, specifically compounds of formula (I) and their pharmaceutically acceptable salts or solvates, are used to reduce uric acid levels and inhibit inflammation, thereby treating or preventing hyperuricemia, gout, gouty inflammations, pain, and uric acid nephropathy.

Benefits of technology

The xanthine compounds significantly reduce uric acid levels and alleviate inflammatory responses, effectively treating or preventing gout, gouty inflammations, pain, and uric acid nephropathy, while also reducing the risk of associated conditions like hypertension, diabetes, and kidney injury.

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Abstract

The present invention relates to the use of a compound of formula (i), a pharmaceutically acceptable salt thereof, a solvate thereof, or a pharmaceutical composition containing it to reduce uric acid levels, prevent or reduce inflammation, and prevent or treat gout. In particular, the present invention relates to the use of a compound of formula (i), a pharmaceutically acceptable salt thereof, a solvate thereof, or a pharmaceutical composition containing it in the manufacture of a drug for the treatment or prevention of hyperuricemia, gout, gouty inflammation, uric acid pain, and nephropathy. r1 represents a hydrogen, a ci-4 alkyl or similar. R2 represents a ci-10 alkyl or similar. R3 represents a halogen or similar.
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