Devices, systems, and methods for recording electrophysiological signals or for stimulating tissue

The conductive frame with insulating layers and metallic components in implantable devices effectively separates neural signals from noise, enhancing signal quality and enabling versatile cranial implantation.

WO2025230781A1 Publication Date: 2025-11-06SYNCHRON AUSTRALIA PTY LTD
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Patent Information

Application Number
PCT/US2025/025854
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-04-30
Filing Date
2025-04-22
Publication Date
2025-11-06

AI Technical Summary

Technical Problem

Existing implantable devices face challenges in effectively separating recorded extracellular neural signals from ambient noise sources while being implantable in various cranial locations, and there is a need for a solution that minimizes noise without increasing complexity.

Method used

The use of a conductive frame with insulating layers and metallic components, where the frame serves as a reference or active electrode, coupled with a signal analyzer to determine voltage signals, allowing for robust noise separation and implantation in different cranial locations.

Benefits of technology

The solution provides improved signal quality by minimizing noise interference, enabling effective neural signal recording and stimulation, and allows for versatile implantation sites within the cranial region.

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Abstract

Disclosed herein are devices, systems, and methods for recording bio-signals and / or stimulating tissue. In one aspect, an implantable medical device is disclosed comprising a conductive frame, one or more insulating layers disposed on the conductive frame, and at least one metallic component affixed to the one or more insulating layers. A first conductive element can be electrically coupled to at least part of the conductive frame and a signal analyzer and a second conductive element can be electrically coupled to the at least one metallic component and the signal analyzer. The signal analyzer can be configured to determine a voltage signal using the conductive frame as the reference electrode and the at least one metallic component as the active electrode. Alternatively, the signal analyzer can also determine a voltage signal using the conductive frame as the active electrode and the at least one metallic component as the reference electrode.
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