Vessel occluder advanceable over an infusion catheter

The microvalve treatment system with a microcatheter and movable occluder addresses inefficiencies in systemic treatments by enhancing drug concentration and reducing reflux, enabling precise infusion into target tissues.

AU2024414613A1Pending Publication Date: 2026-07-16TRISALUS LIFE SCIENCES INC

Patent Information

Authority / Receiving Office
AU · AU
Patent Type
Applications
Current Assignee / Owner
TRISALUS LIFE SCIENCES INC
Filing Date
2024-12-30
Publication Date
2026-07-16

AI Technical Summary

Technical Problem

Existing systemic treatments for diseases like cancer and diabetes face challenges due to insufficient drug concentration at target tissues, leading to inefficacy and systemic side effects, while standard end-hole catheters lack control over infusion and can cause reflux to non-target areas.

Method used

A microvalve treatment system comprising a microcatheter and a longitudinally movable microvalve vessel occluder that can be advanced over the catheter to control infusion and occlude blood vessels, allowing targeted delivery of therapeutic agents to specific locations within the vasculature.

Benefits of technology

Enhances drug concentration at target tissues by reducing reflux and improving delivery efficiency, minimizing systemic side effects, and enabling precise infusion into smaller vessels.

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Abstract

A treatment system includes a catheter and a separate microvalve that is longitudinally displaceable relative and over the catheter to a target location in the vasculature. The catheter and microvalve include markers to register the location of the microvalve relative to the catheter. The treatment system may be used in a method of delivering a therapeutic agent to through a vasculature of a patient to a solid tumor in an organ.
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