Waxberry polyphenol chromocor extract, and preparations and applications thereof

Abstract

The invention provides a bayberry polyphenol flavone extract, which is obtained by the methods as follows: the fragment of a bayberry plant is used as raw ingredient, ethanol water solution of 50 to 80 percent is added, wherein, the ethanol water solution is 4 to 7 times of the quality of the fragment; the mixture is extracted for 1 to 3 hours at 60 to 100 DEG C in a heat preservation way and is filtered to obtain extracting solution; the volume concentration of alcohol in the extracting solution is adjusted to reach 75 percent to 80 percent; the extracting solution is mixed well, let stand for 0.5 to 2 hours, and then filtered; the alcohol is recovered from filter liquor and is concentrated to obtain macroporous adsorption resin on a paste; the macroporous adsorption resin is eluted by using distilled water, then by using the ethanol water solution of 10 to 20 percent to remove impurities, and then by using the ethanol water solution of 60 to 90 percent at last; eluate is collected to recover the alcohol which is dried until the liquid water content is less than 12 percent, so as to obtain the bayberry polyphenol flavone extract. The invention provides the bayberry polyphenol flavone extract which has three-fold efficacy, namely assistance efficacy on blood lipid reduction, hypoglycemic efficacy, and blood-pressure reduction efficacy, and no similar products are developed andmanufactured until now. Compared with existing products at home and abroad, the bayberry polyphenol flavone extract has more overall efficacies, and better effect for regaining normal blood-fat, blood sugar and blood pressure of people in need.

Description

(1) Technical field

[0001] The invention relates to a bayberry polyphenol flavonoid extract with triple functions of lowering blood fat, blood sugar and blood pressure, and its preparation and application. (2) Background technology

[0002] A large number of people at home and abroad have physiological phenomena of high blood lipids, blood sugar, and blood pressure. They are in great need of functional food conditioning with natural plants as raw materials, especially functional foods developed from food resources. The market demand is high. At present, people with high blood lipids are often accompanied by high blood sugar or high blood pressure, and there are many people with high blood lipids, blood sugar and blood pressure. However, the existing products are all single-function products, so it is very necessary to develop a product with multiple functions. Functional foods that assist in reducing blood fat, blood sugar, and blood pressure are supplied to the market to i...

Examples

Embodiment 1

[0021] Get 10 kilograms of red bayberry fruit (produced in Cixi City, Zhejiang Province), grind and pulverize the fruit core, add 50 kilograms of 80% volume concentration of ethanol aqueous solution, extract at 80 ° C for 1 hour, filter to obtain the extract, and vacuum recover the ethanol from the extract , concentrated to a relative density of about 1.10 to obtain 573 grams of paste. Take macroporous adsorption resin (type AB-8, produced by Tianjin Nankai Hecheng Technology Co., Ltd.), soak in absolute ethanol for 24 hours, soak in distilled water for 24 hours, and wash three times, drain the water, take 240L wet macroporous adsorption resin Column packing. Immerse the resin in distilled water, put the paste on the column, rinse with 480L of distilled water, discard the eluent, rinse with 480L of 10% volume concentration ethanol aqueous solution, and discard the ethanol after recovering the ethanol by vacuum distillation. Rinse with 1080L of 70% ethanol aqueous solution, co...

Embodiment 2

[0023] Get 8 kilograms of bayberry bark (produced in Cixi City, Zhejiang Province), grind and pulverize, add 16 kilograms of 70% volume concentration of ethanol aqueous solution, extract at 60 ° C for 3 hours, filter to obtain the extract, and add 95% volume to the extract The concentration of ethanol was 1.7 liters, stirred evenly, stood still for 2 hours, filtered again, and the filtrate was vacuum recovered ethanol, concentrated to a relative density of about 1.15 to obtain 1487 grams of paste. Take macroporous adsorption resin (AB-8 type, produced by Tianjin Nankai Hecheng Technology Co., Ltd.), soak it in absolute ethanol for 24 hours, soak in distilled water for 24 hours, and wash three times, drain the water, take 480L wet macroporous adsorption resin Column packing. Immerse the resin in distilled water, put the paste on the column, rinse with 960L of distilled water, discard the eluent, rinse with 960L of 20% volume concentration ethanol aqueous solution, and discard t...

Embodiment 3

[0025] Get 15 kilograms of red bayberry leaves (produced in Xianju County, Zhejiang Province), grind and pulverize, add 60 kilograms of 50% volume concentration of ethanol aqueous solution, extract at 100 ° C for 2 hours, filter to obtain the extract, and add 95% volume of the extract Concentration of 20 liters of ethanol, stir evenly, stand still for 0.5 hour, filter again, the filtrate is vacuum recovered ethanol, concentrated to a relative density of about 1.10, to obtain 2657 grams of paste. Take macroporous adsorption resin (AB-8 type, produced by Tianjin Nankai Hecheng Technology Co., Ltd.), soak it in absolute ethanol for 24 hours, soak in distilled water for 24 hours, and wash three times, drain the water, take 600L wet macroporous adsorption resin Column packing. Immerse the resin in distilled water, put the paste on the column, rinse with 1200L of distilled water, discard the eluent, rinse with 1200L of 15% ethanol aqueous solution, and discard the ethanol after reco...

(1) Technical field

[0001] The invention relates to a bayberry polyphenol flavonoid extract with triple functions of lowering blood fat, blood sugar and blood pressure, and its preparation and application. (2) Background technology

[0002] A large number of people at home and abroad have physiological phenomena of high blood lipids, blood sugar, and blood pressure. They are in great need of functional food conditioning with natural plants as raw materials, especially functional foods developed from food resources. The market demand is high. At present, people with high blood lipids are often accompanied by high blood sugar or high blood pressure, and there are many people with high blood lipids, blood sugar and blood pressure. However, the existing products are all single-function products, so it is very necessary to develop a product with multiple functions. Functional foods that assist in reducing blood fat, blood sugar, and blood pressure are supplied to the market to i...

Examples

Embodiment 1

[0021] Get 10 kilograms of red bayberry fruit (produced in Cixi City, Zhejiang Province), grind and pulverize the fruit core, add 50 kilograms of 80% volume concentration of ethanol aqueous solution, extract at 80 ° C for 1 hour, filter to obtain the extract, and vacuum recover the ethanol from the extract , concentrated to a relative density of about 1.10 to obtain 573 grams of paste. Take macroporous adsorption resin (type AB-8, produced by Tianjin Nankai Hecheng Technology Co., Ltd.), soak in absolute ethanol for 24 hours, soak in distilled water for 24 hours, and wash three times, drain the water, take 240L wet macroporous adsorption resin Column packing. Immerse the resin in distilled water, put the paste on the column, rinse with 480L of distilled water, discard the eluent, rinse with 480L of 10% volume concentration ethanol aqueous solution, and discard the ethanol after recovering the ethanol by vacuum distillation. Rinse with 1080L of 70% ethanol aqueous solution, co...

Embodiment 2

[0023] Get 8 kilograms of bayberry bark (produced in Cixi City, Zhejiang Province), grind and pulverize, add 16 kilograms of 70% volume concentration of ethanol aqueous solution, extract at 60 ° C for 3 hours, filter to obtain the extract, and add 95% volume to the extract The concentration of ethanol was 1.7 liters, stirred evenly, stood still for 2 hours, filtered again, and the filtrate was vacuum recovered ethanol, concentrated to a relative density of about 1.15 to obtain 1487 grams of paste. Take macroporous adsorption resin (AB-8 type, produced by Tianjin Nankai Hecheng Technology Co., Ltd.), soak it in absolute ethanol for 24 hours, soak in distilled water for 24 hours, and wash three times, drain the water, take 480L wet macroporous adsorption resin Column packing. Immerse the resin in distilled water, put the paste on the column, rinse with 960L of distilled water, discard the eluent, rinse with 960L of 20% volume concentration ethanol aqueous solution, and discard t...

Embodiment 3

[0025] Get 15 kilograms of red bayberry leaves (produced in Xianju County, Zhejiang Province), grind and pulverize, add 60 kilograms of 50% volume concentration of ethanol aqueous solution, extract at 100 ° C for 2 hours, filter to obtain the extract, and add 95% volume of the extract Concentration of 20 liters of ethanol, stir evenly, stand still for 0.5 hour, filter again, the filtrate is vacuum recovered ethanol, concentrated to a relative density of about 1.10, to obtain 2657 grams of paste. Take macroporous adsorption resin (AB-8 type, produced by Tianjin Nankai Hecheng Technology Co., Ltd.), soak it in absolute ethanol for 24 hours, soak in distilled water for 24 hours, and wash three times, drain the water, take 600L wet macroporous adsorption resin Column packing. Immerse the resin in distilled water, put the paste on the column, rinse with 1200L of distilled water, discard the eluent, rinse with 1200L of 15% ethanol aqueous solution, and discard the ethanol after reco...

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