A kind of preparation method and application of traditional Chinese medicine hydrogel

Abstract

The invention provides a preparation method and application of a traditional Chinese medicine hydrogel. The hydrogel is prepared from Phellodendron Phellodendri extract and a hydrophilic matrix. After external use, the hydrogel can inhibit scar hyperplasia, promote scar softening, and prevent postoperative scars The production of tissue, and the preparation method is simple and the side effects are small, so it can be widely used in the prevention of postoperative scars in surgical patients.

Description

technical field

[0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine hydrogel for preventing postoperative scar formation. Background technique

[0002] Scarring is an inevitable result of wound repair. Keloids or scar hyperplasia that accompany wound healing not only affect the appearance but also lead to varying degrees of tissue and organ dysfunction. Because it is difficult to control, there is no very satisfactory treatment plan in China so far. The fundamental principle of scar treatment is to remove the lesion and prevent its recurrence by inhibiting the proliferation of fibroblasts and their collagen synthesis, secretion or deposition. Currently, effective treatment options mainly include surgery, drug therapy, radiation therapy, laser, and cryotherapy. Drug therapy plays an important role in the treatment of scar.

[0003] Phellodendron amurense is the dry bark of Phellodendron amurense (Phe...

Examples

Embodiment Construction

[0022] The present invention is described in detail below in conjunction with embodiment.

[0023] Through previous clinical observations, it was found that Phellodendron Phellodendri Extract (Phelloderma Phellodendron Liquid) can effectively prevent postoperative scar formation. Based on the previous research on Phellodendron Phellodendri and hydrogel, it is considered to use hydrogel in the prevention and treatment of postoperative scar. Specifically, as follows:

[0024] (1) the present invention provides a kind of preparation method of the Chinese medicine hydrogel that is used to prevent postoperative cicatrix, comprises the following steps:

[0025] 1) Add 15g Phellodendron Phellodendron to 200mL water, heat to boil, after boiling, continue to decoct on low heat for 2.0 hours, then naturally cool to room temperature, after cooling, use sterile gauze and funnel to filter to obtain 50g of Liquid A (that is, Phellodendron Phellodendron Liquid);

[0026] 2) Weigh 80g of pol...

technical field

[0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine hydrogel for preventing postoperative scar formation. Background technique

[0002] Scarring is an inevitable result of wound repair. Keloids or scar hyperplasia that accompany wound healing not only affect the appearance but also lead to varying degrees of tissue and organ dysfunction. Because it is difficult to control, there is no very satisfactory treatment plan in China so far. The fundamental principle of scar treatment is to remove the lesion and prevent its recurrence by inhibiting the proliferation of fibroblasts and their collagen synthesis, secretion or deposition. Currently, effective treatment options mainly include surgery, drug therapy, radiation therapy, laser, and cryotherapy. Drug therapy plays an important role in the treatment of scar.

[0003] Phellodendron amurense is the dry bark of Phellodendron amurense (Phe...

Examples

Embodiment Construction

[0022] The present invention is described in detail below in conjunction with embodiment.

[0023] Through previous clinical observations, it was found that Phellodendron Phellodendri Extract (Phelloderma Phellodendron Liquid) can effectively prevent postoperative scar formation. Based on the previous research on Phellodendron Phellodendri and hydrogel, it is considered to use hydrogel in the prevention and treatment of postoperative scar. Specifically, as follows:

[0024] (1) the present invention provides a kind of preparation method of the Chinese medicine hydrogel that is used to prevent postoperative cicatrix, comprises the following steps:

[0025] 1) Add 15g Phellodendron Phellodendron to 200mL water, heat to boil, after boiling, continue to decoct on low heat for 2.0 hours, then naturally cool to room temperature, after cooling, use sterile gauze and funnel to filter to obtain 50g of Liquid A (that is, Phellodendron Phellodendron Liquid);

[0026] 2) Weigh 80g of pol...