Antibody potency assay

By utilizing a cell-based approach to activate reporter receptors using immobilized target antigens and Fcγ receptors of phagocytes, the accuracy and efficiency issues of existing antibody potency assays have been resolved, enabling rapid and accurate peptide potency assays.

CN113711037BActive Publication Date: 2026-07-03GENENTECH INC
View PDF 33 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
GENENTECH INC
Filing Date
2020-04-17
Publication Date
2026-07-03

Smart Images

  • Figure BDA0003306455680000271
    Figure BDA0003306455680000271
  • Figure BDA0003306455680000272
    Figure BDA0003306455680000272
  • Figure BDA0003306455680000273
    Figure BDA0003306455680000273
Patent Text Reader

Abstract

The invention provides a cell-based assay for measuring the potency of an antibody. An antigen bound to a surface is contacted with the antibody, which in turn is contacted with a reporter cell. Compositions and kits are also contemplated.
Need to check novelty before this filing date? Find Prior Art