Use of bacteroides cacae in the preparation of a drug for preventing and treating heart failure
CN115887502BActive Publication Date: 2026-06-23FOURTH MILITARY MEDICAL UNIVERSITY
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- FOURTH MILITARY MEDICAL UNIVERSITY
- Filing Date
- 2022-11-29
- Publication Date
- 2026-06-23
AI Technical Summary
Technical Problem
目前，还没有一种细菌可以用于心力衰竭和病理性心脏重构的预防与治疗
Benefits of technology
[0012]1、本发明首次发现给心肌梗死后小鼠口服粪副拟杆菌(PM菌)可显著地改善心力衰竭与病理性心脏重构，其中1×108CFU PM/天的治疗效果可以与一线用药美托洛尔相当；
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Smart Images
Figure CN115887502B_ABST
Abstract
The application relates to the technical field of microbial application, and particularly discloses application of Bacteroides caccae in preparation of a medicine for preventing and treating heart failure. The Bacteroides caccae (PM bacteria) in the application can significantly improve heart failure and pathological cardiac remodeling, and the prepared medicine is used for preventing and treating heart failure of mice, and the dose is 1x10 8 The effect of 1x10 CFU PM / day can be equivalent to that of metoprolol as a first-line drug.
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