Negative pressure protected aerosol simulation chamber

By designing a negative pressure protection zone and multiple disinfection devices in the test chamber, the problem of aerosol escape was solved, achieving rapid and thorough disinfection and ensuring environmental safety.

CN116085913BActive Publication Date: 2026-06-16BIOSAFETY RES CENT YANGTZE RIVER DELTA IN ZHANGJIAGANG

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
BIOSAFETY RES CENT YANGTZE RIVER DELTA IN ZHANGJIAGANG
Filing Date
2023-02-28
Publication Date
2026-06-16

AI Technical Summary

Technical Problem

The existing test chambers cause aerosol release due to pressure changes when the chamber doors are opened and closed, posing a risk of environmental pollution. Furthermore, the purification capacity is insufficient and cannot effectively prevent aerosol diffusion.

Method used

A negative pressure protected aerosol simulation chamber is designed, comprising a core chamber, a negative pressure protection zone, and a power maintenance room. It employs multiple disinfection devices and an air filtration system, combined with a disinfectant spray device and ultraviolet germicidal lamps, to achieve thorough aerosol elimination.

🎯Benefits of technology

It effectively reduces the probability of aerosol dispersion, achieves rapid and thorough disinfection, ensures environmental safety, and avoids aerosol pollution.

✦ Generated by Eureka AI based on patent content.

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Abstract

This invention belongs to the field of aerosol simulation chamber technology, specifically relating to a negative pressure protected aerosol simulation chamber, comprising a core chamber, a power maintenance room, and a negative pressure protection zone. The core chamber is located adjacent to the negative pressure protection zone, which is also adjacent to the core chamber. The power maintenance room is located adjacent to both the core chamber and the negative pressure protection zone. The core chamber is composed of a stainless steel frame and tempered glass walls, with the joints between the stainless steel frame and the tempered glass sealed. The core chamber has an airtight door located on the wall adjacent to the negative pressure protection zone. A transfer window and an operating window are also located on the wall with the airtight door. The externally connected negative pressure protection zone prevents aerosols from escaping into the external environment due to pressure changes caused by door opening and closing. Both the core chamber and the negative pressure protection zone's gas paths include multiple disinfection devices, fundamentally solving the environmental pollution problems that may arise from aerosol generation experiments.
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Description

Technical Field

[0001] This invention belongs to the field of aerosol simulation chamber technology, specifically relating to a negative pressure protected aerosol simulation chamber. Background Technology

[0002] Aerosols are gaseous dispersion systems composed of solid or liquid particles suspended in a gaseous medium. The density of these solid or liquid particles can differ slightly from the density of the gaseous medium, or it can differ significantly. Aerosols are highly unstable colloidal dispersion systems, but due to Brownian motion, they also possess a certain degree of relative stability. Although existing test chambers have good airtightness in terms of manufacturing processes, the instantaneous pressure change when the chamber door is opened or closed causes contaminated aerosols to leak out. To prevent aerosols from diffusing into a positive pressure environment, the manufacturing process creates a negative pressure environment to fix the airflow path.

[0003] Aerosols contain suspended viruses, bacteria, fungi, and their byproducts. Most existing test chambers use disposable filtration and disinfection methods, which are too simplistic and lack sufficient purification power. This results in aerosol residues inside the test chamber. When the airtight door of the test chamber is opened, the difference in air pressure between the inside and outside causes some aerosols to escape into the environment outside the test chamber, which poses a certain danger. Summary of the Invention

[0004] The purpose of this invention is to provide a negative pressure protected aerosol simulation chamber. The negative pressure protection zone connected to the outside of the aerosol simulation chamber prevents the aerosol inside the chamber from escaping into the external environment due to pressure changes caused by opening and closing the chamber door. The air paths of both the core chamber and the negative pressure protection zone contain multiple disinfection devices, which fundamentally solves the environmental pollution problem that may be caused by aerosol generation experiments.

[0005] The specific technical solution adopted by this invention is as follows:

[0006] A negative pressure protected aerosol simulation chamber includes a core chamber, a power maintenance room, and a negative pressure protection zone. The core chamber is located adjacent to the negative pressure protection zone, and the power maintenance room is located adjacent to both the core chamber and the negative pressure protection zone. The core chamber is composed of a stainless steel frame and tempered glass walls, with the joints between the stainless steel frame and the tempered glass sealed. The core chamber has an airtight door located on the wall adjacent to the negative pressure protection zone. A transfer window and an operation window are also provided on the wall of the airtight door. The top of the core chamber is equipped with lighting equipment, a stirring fan, an ultraviolet germicidal lamp, an air filtration system, and a disinfectant spray device. A floor track and an operating platform are installed inside the core chamber. The operating platform is positioned above the floor track and can slide on it. The core chamber is also equipped with an intelligent system touch screen display.

[0007] The negative pressure protection zone is a high-grade airtight room made of stainless steel. A buffer room is set at the entrance of the negative pressure protection zone. Both the entrance and exit of the buffer room are equipped with airtight doors for the negative pressure zone. The top of the negative pressure protection zone is also equipped with lighting equipment, ultraviolet germicidal lamps, an air filtration system and a disinfectant spraying device. The interior of the negative pressure protection zone is also equipped with a live toxic wastewater system and a touch-screen intelligent environmental monitoring system.

[0008] The power maintenance room is equipped with a constant temperature and humidity air conditioning unit, a fresh air system and a high-efficiency filter exhaust port. The entrance of the power maintenance room is equipped with an airtight door, which is located on the side away from the main body of the core module and the negative pressure protection zone.

[0009] In a preferred embodiment, the disinfectant spraying device includes a spray fan, a spray frame, an atomizing nozzle, and a spray guide pipe. The spray frame is installed on the top of the core module, and the atomizing nozzle is installed at the bottom of the spray frame. The atomizing nozzle is connected to a disinfectant delivery pipe. The spray guide pipe is rotatably connected to the outer side of the bottom of the spray frame. The spray guide pipe is driven and controlled by a motor. The spray guide pipe has a 135° bend in the middle, and the spray fan is installed at the bottom inside the spray guide pipe.

[0010] In a preferred embodiment, the top and floor of the core compartment are made of stainless steel, and the side of the core compartment near the power maintenance room is made of a panel. The stainless steel frame of the core compartment is connected to the top, floor, and panel of the core compartment by welding and sealing.

[0011] In a preferred embodiment, air filters are provided on the top of both the core module and the negative pressure protection zone, and the air filters are connected to an air filtration system.

[0012] In a preferred embodiment, the air filtration system includes air conditioning unit ducts, air filtration equipment, an ozone generator, and a valve. There are several air conditioning unit ducts. The ozone generator is installed on the top of the core module and connected to an air filter port on the top of the core module. There are two air filtration devices; one is connected to a negative pressure protection zone via an air conditioning unit duct, and the other is connected to a constant temperature and humidity air conditioning unit in the power maintenance room via an air conditioning unit duct. Both air filtration devices are connected via air conditioning unit ducts, and the air filtration device connected to the negative pressure protection zone is also connected to the ozone generator via an air conditioning unit duct.

[0013] In a preferred embodiment, an air communication valve is provided on one side of the core module, and the air communication valve is located below the operating window.

[0014] In a preferred embodiment, a pressure gauge is provided above the item transfer window, the pressure gauge being used to monitor the air pressure of the core module and the negative pressure protection zone.

[0015] In a preferred embodiment, a top compartment is provided on top of the core module, and the air filtration system is located in the top compartment.

[0016] In a preferred embodiment, the live virus wastewater system comprises a sterilization tank, a mixing device, a pipeline pump, and a breather. The sterilization tank is connected to the other components by welding and is sealed.

[0017] In a preferred embodiment, both the core module and the walls of the negative pressure protection zone are equipped with circulating purification fans, which work in conjunction with a stirring fan to accelerate airflow.

[0018] The technical effects achieved by this invention are as follows:

[0019] The invention utilizes a multi-level disinfection system installed inside the core cabin, along with a fresh air system that circulates air to achieve disinfection, resulting in better disinfection and faster completion of aerosol disinfection.

[0020] The negative pressure protection zone set up in this invention, when used in conjunction with the core cabin body, can effectively reduce the probability of the escape of aerosols that have not been completely purified inside the core cabin body when entering or exiting the core cabin body. In addition, the negative pressure protection zone is equipped with the same disinfection equipment as the core cabin body, which can thoroughly disinfect the trace amounts of aerosols that have escaped into the negative pressure protection zone.

[0021] The disinfectant spraying device of this invention can atomize the disinfectant liquid and spray it out. The spray guide tube rotates continuously, and the spray fan blows the atomized disinfectant spray evenly on the core cabin and the interior of the negative pressure protection zone to achieve a better disinfection effect. Attached Figure Description

[0022] Figure 1 This is a top view of the negative pressure protection zone of the negative pressure protection aerosol test chamber of the present invention;

[0023] Figure 2 This is a top view of the core chamber and power maintenance room of the negative pressure protection aerosol test chamber of the present invention;

[0024] Figure 3 This is a front view of the core chamber and power maintenance room of the negative pressure protection aerosol test chamber of the present invention;

[0025] Figure 4 This is a schematic diagram of the waste gas and wastewater purification system of the negative pressure protected aerosol test chamber of the present invention;

[0026] Figure 5 This is a schematic diagram of the negative pressure protective aerosol test chamber spray system of the present invention.

[0027] The attached diagram lists the components represented by each number as follows:

[0028] 1. Core module main body; 2. Lighting equipment; 3. Air filter port; 4. Stirring fan; 5. Ground rail; 6. Ultraviolet germicidal lamp; 7. Control panel; 8. Air filtration system; 9. Intelligent system touch screen display; 10. Air connecting valve; 11. Core module airtight door; 12. Power maintenance room; 13. Constant temperature and humidity air conditioning unit; 14. Air conditioning unit piping; 15. Disinfectant spray device; 16. Air filtration equipment; 17. Circulating purification fan; 18. Fresh air system; 19. Maintenance room airtight door; 20. Item transfer window; 21. Pressure gauge; 22. Top compartment; 23. Control window; 24. Negative pressure protection zone; 25. Buffer room; 26. Negative pressure zone airtight door; 27. Ozone device; 28. Gas valve; 29. ​​Three-way valve; 30. Live toxic wastewater system; 31. Spray fan; 32. Spray frame; 33. Atomizing nozzle; 34. Spray guide pipe. Detailed Implementation

[0029] To make the above-mentioned objects, features and advantages of the present invention more apparent and understandable, the specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

[0030] Many specific details are set forth in the following description in order to provide a full understanding of the invention. However, the invention may also be practiced in other ways different from those described herein, and those skilled in the art can make similar extensions without departing from the spirit of the invention. Therefore, the invention is not limited to the specific embodiments disclosed below.

[0031] Secondly, the term "an embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The phrase "in a preferred embodiment" appearing in different places throughout this specification does not necessarily refer to the same embodiment, nor is it a single or selective embodiment that mutually excludes other embodiments.

[0032] Secondly, the present invention is described in detail with reference to the schematic diagrams. When detailing the embodiments of the present invention, for ease of explanation, the cross-sectional views illustrating the device structure may be partially enlarged, not according to the usual scale. Furthermore, the schematic diagrams are merely examples and should not limit the scope of protection of the present invention. In addition, actual fabrication should include three-dimensional spatial dimensions of length, width, and depth.

[0033] Please see the appendix Figures 1 to 4 As shown, this is the first embodiment of the present invention. This embodiment provides a negative pressure protected aerosol simulation chamber, including a core chamber body 1, a power maintenance room 12, and a negative pressure protection zone 24. The core chamber body 1 is located adjacent to the negative pressure protection zone 24, and the negative pressure protection zone 24 is located adjacent to the core chamber body 1. The power maintenance room 12 is located adjacent to both the core chamber body 1 and the negative pressure protection zone 24. The core chamber body 1 is composed of a stainless steel frame and tempered glass walls, and the connection between the stainless steel frame and the tempered glass is sealed. The core chamber body 1 is provided with a core chamber airtight door 11, which is located on the wall adjacent to the core chamber body 1 and the negative pressure protection zone 24. Items are also placed on the wall of the core chamber airtight door 11. The system includes a transfer window 20 and an operation window 23. A pressure gauge 21 is installed above the transfer window 20 to monitor the air pressure of the core cabin body 1 and the negative pressure protection zone 24. An air communication valve 10 is installed on one side of the core cabin body 1, located below the operation window 23. The top of the core cabin body 1 is equipped with a lighting device 2, a stirring fan 4, an ultraviolet germicidal lamp 6, an air filtration system 8, and a disinfectant spraying device 15. A top chamber 22 is installed on the top of the core cabin body 1, and the air filtration system 8 is installed inside the top chamber 22. A ground rail 5 and an operation table 7 are installed inside the core cabin body 1. The operation table 7 is located above the ground rail 5 and can slide on the ground rail 5. The core cabin body 1 is equipped with an intelligent system touch screen display 9.

[0034] The entire core module 1 is installed by welding, with tight and firm connections. This ensures the airtightness of the core module 1 while withstanding long-term negative pressure from the external environment. The stirring fan 4 installed inside can agitate the airflow and accelerate the uniformization of aerosol concentration within the core module 1. The ultraviolet germicidal lamp 6 and disinfectant spray device 15 installed on the top of the core module 1 can perform terminal disinfection of pollutants within the core module 1. Furthermore, the air filtration system 8 can extract the air from the core module 1, purify it, and then reintroduce it into the core module 1, thus completing the air purification process.

[0035] The negative pressure protection zone 24 is a high-grade airtight room made of stainless steel. A buffer room 25 is set at the entrance of the negative pressure protection zone 24. Negative pressure zone airtight doors 26 are installed at both the entrance and exit of the buffer room 25. The top of the negative pressure protection zone 24 is also equipped with lighting equipment 2, ultraviolet germicidal lamps 6, air filtration system 8 and disinfectant spray device 15. The interior of the negative pressure protection zone 24 is also equipped with a live toxic wastewater system 30 and a touch-screen intelligent environmental monitoring system.

[0036] The buffer room 25 set at the entrance of the negative pressure protection zone 24 can buffer personnel when they enter and exit, and prevent the air pressure in the negative pressure protection zone 24 from changing drastically when the airtight door 26 of the negative pressure zone is opened and closed directly. The ultraviolet germicidal lamp 6 and the disinfectant spray device 15 set at the top of the negative pressure protection zone 24 can thoroughly disinfect the trace amount of aerosol that escapes into the negative pressure protection zone 24, thereby effectively preventing the aerosol from escaping. The air filtration system 8 set above the negative pressure protection zone 24 can extract the original air in the negative pressure protection zone 24, purify it and then reintroduce it into the negative pressure protection zone 24.

[0037] Furthermore, the intelligent environmental monitoring system includes equipment monitoring units, personnel monitoring units, parameter revision units, and alarm units, which can monitor the regional environmental status in real time.

[0038] The power maintenance room 12 is equipped with a constant temperature and humidity air conditioning unit 13, a fresh air system 18 and a high-efficiency filter exhaust port. The entrance of the power maintenance room 12 is equipped with a maintenance room airtight door 19, which is located on the side away from the core module 1 and the negative pressure protection zone 24. The airtightness of the power maintenance room 12 is at the same level as that of the core module 1 and the negative pressure protection zone 24.

[0039] The airtight door 19 of the maintenance room is located in a position that is not connected to the core module 1 and the negative pressure protection zone 24. It is not affected by the negative pressure protection zone 24 during the maintenance process, nor does it affect the pressure of the negative pressure protection zone 24. The constant temperature and humidity air conditioning unit 13 is combined with the air filtration system 8, which can purify the air while regulating the temperature and humidity of the air, ensuring that the core module 1 and the negative pressure protection zone 24 are in a constant temperature and humidity environment.

[0040] In a preferred embodiment, please also refer to Figure 3 and Figure 5 The disinfectant spraying device 15 includes a spray fan 31, a spray frame 32, an atomizing nozzle 33, and a spray guide pipe 34. The spray frame 32 is installed on the top of the core compartment body 1. The atomizing nozzle 33 is installed at the bottom of the spray frame 32 and is connected to the disinfectant delivery pipe. The spray guide pipe 34 is rotatably connected to the outer side of the bottom of the spray frame 32. The spray guide pipe 34 is driven and controlled by a motor to change direction. A 135° bend is provided in the middle of the spray guide pipe 34. The spray fan 31 is installed at the bottom inside the spray guide pipe 34.

[0041] In this embodiment, when disinfectant is sprayed through the disinfectant spraying device 15, it is delivered to the atomizing nozzle 33 via the disinfectant delivery pipe, atomized, and then sprayed out. At the same time, the spray fan 31 can agitate the airflow, increasing the spraying distance of the atomized disinfectant. Meanwhile, the motor can control the direction of the spray guide pipe 34, so that the atomized disinfectant can be evenly sprayed in the core cabin body 1 and the negative pressure protection zone 24, achieving a better disinfection effect.

[0042] Secondly, please refer to it again. Figure 2 The top and floor of the core module 1 are made of stainless steel. The side of the core module 1 closest to the power maintenance room 12 is made of a panel. The stainless steel frame of the core module 1 is connected to the top, floor and panel of the core module 1 by welding.

[0043] The connecting walls between the core module 1 and the power maintenance room 12 are connected by welding and sealing within the frames of the core module 1 and the power maintenance room 12, which ensures both the strength of the connection and the airtightness of the connection.

[0044] Please refer to the following: Figure 1 , Figure 2 and Figure 3 Air filters 3 are installed on the top of both the core module 1 and the negative pressure protection zone 24. The air filters 3 are connected to the air filtration system 8. Circulating purification fans 17 are installed on the walls of both the core module 1 and the negative pressure protection zone 24. The circulating purification fans 17 work in conjunction with the stirring fan 4 to agitate the airflow and accelerate the aerosol concentration in the core module 1 to reach a uniform state.

[0045] As mentioned above, the air filter port 3 is the inlet for air circulation. After being purified by the air filtration system 8, the circulating air is released downwards from the air filter port 3 into the core cabin body 1 and the negative pressure protection zone 24.

[0046] Please refer to the following: Figure 2 , Figure 3 and Figure 4 The air filtration system 8 includes air conditioning unit ducts 14, air filtration devices 16, ozone generators 27, and valves 28. There are several air conditioning unit ducts 14. The ozone generators 27 are installed on the top of the core module 1 and are connected to the air filter port 3 on the top of the core module 1. There are two air filtration devices 16. One air filtration device 16 is connected to the negative pressure protection zone 24 through the air conditioning unit ducts 14, and the other air filtration device 16 is connected to the constant temperature and humidity air conditioning unit 13 of the power maintenance room 12 through the air conditioning unit ducts 14. The two air filtration devices 16 are connected through the air conditioning unit ducts 14. The air filtration device 16 connected to the negative pressure protection zone is also connected to the ozone generator 27 through the air conditioning unit ducts 14.

[0047] In the above process, after the air is purified by the ultraviolet germicidal lamp 6 and the disinfectant spray device 15, it is first regulated by the constant temperature and humidity air conditioning unit 13 in the power maintenance room to adjust the air humidity and temperature. The air valve 28 is connected to the fresh air system 18 to control the air flow. After passing through the fresh air system 18, the air is filtered by the air filtration system 8 and released downwards from the air filter port 3 into the core cabin body 1 and the negative pressure protection zone 24. In addition, when the ozone device 27 is turned on, the ozone sterilization function is also carried out simultaneously when the air is filtered by the air filtration system 8 before entering the core cabin body 1. Specifically, for the air filtration system, the air in the core cabin body 1 is first filtered by an air filtration device 16. After the first filtration, the air is transported through the air conditioning unit duct 14 and merged with the air in the negative pressure protection zone 24 to another air filtration device 16 for a second filtration. After the second filtration, the air is introduced into the core cabin body 1 and the negative pressure protection zone 24 from the air filter port 3.

[0048] The negative pressure protection zone 24 can be adjusted to a negative pressure state by adjusting the air supply and exhaust volume.

[0049] Furthermore, it consists of a housing, a HEPA filter, a sealed door, a biological airtight isolation valve, a support frame, and various interfaces and valves. Disinfection is mainly achieved through disinfection interfaces set up upstream and downstream of the filter in the housing, in conjunction with a gas disinfectant generator and a gas circulation disinfection device, to achieve in-situ disinfection of the air filtration equipment 16.

[0050] Furthermore, a three-way valve 29 is installed at the air conditioning unit duct 14 connected to the fresh air system 18, which can control the direction of airflow.

[0051] Secondly, please refer to it again. Figure 4 The live toxic wastewater system 30 consists of a sterilization tank, a mixing device, a pipeline pump, and a breather. The sterilization tank is connected to the other components by welding and is sealed.

[0052] The aforementioned live toxic wastewater system 30 is capable of harmlessly treating the high-risk waste liquid and wastewater discharged during experimental operation.

[0053] The above description is merely a preferred embodiment of the present invention. It should be noted that those skilled in the art can make various improvements and modifications without departing from the principles of the present invention, and these improvements and modifications should also be considered within the scope of protection of the present invention. Structures, devices, and operating methods not specifically described or explained in this invention are implemented according to conventional methods in the art unless otherwise specified or limited.

Claims

1. A negative pressure protected aerosol simulation chamber, characterized in that: The system includes a core module (1), a power maintenance room (12), and a negative pressure protection zone (24). The core module (1) is located adjacent to the negative pressure protection zone (24), and the negative pressure protection zone (24) is located adjacent to the core module (1). The power maintenance room (12) is located adjacent to both the core module (1) and the negative pressure protection zone (24). The core module (1) is composed of a stainless steel frame and tempered glass walls, and the connection between the stainless steel frame and the tempered glass is sealed. The core module (1) is equipped with a core module airtight door (11), which is located in the core. At the wall adjacent to the main body (1) and the negative pressure protection zone (24), the wall of the airtight door (11) of the core cabin is also provided with a transfer window (20) and an operation window (23). The top of the main body (1) of the core cabin is provided with a lighting device (2), a stirring fan (4), an ultraviolet germicidal lamp (6), an air filtration system (8) and a disinfectant spraying device (15). The main body (1) of the core cabin is provided with a ground rail (5) and an operating table (7). The operating table (7) is located above the ground rail (5) and can slide on the ground rail (5). The main body (1) of the core cabin is equipped with an intelligent system touch screen (9). The negative pressure protection zone (24) is a high-grade airtight room made of stainless steel plate. A buffer room (25) is set at the entrance of the negative pressure protection zone (24). Negative pressure zone airtight doors (26) are installed at the entrance and exit of the buffer room (25). Lighting equipment (2), ultraviolet germicidal lamps (6), air filtration system (8) and disinfectant spray device (15) are also installed on the top of the negative pressure protection zone (24). The interior of the negative pressure protection zone (24) is also equipped with a live virus wastewater system (30) and a touch-screen intelligent environmental monitoring system. The power maintenance room (12) is equipped with a constant temperature and humidity air conditioning unit (13), a fresh air system (18) and a high-efficiency filter exhaust port. The entrance of the power maintenance room (12) is provided with a maintenance room airtight door (19), which is located on the side away from the core module (1) and the negative pressure protection zone (24). The disinfectant spraying device (15) includes a spray fan (31), a spray frame (32), an atomizing nozzle (33), and a spray guide pipe (34). The spray frame (32) is installed on the top of the core module (1). An atomizing nozzle (33) is installed at the bottom of the spray frame (32). The atomizing nozzle (33) is connected to the disinfectant delivery pipe. The spray guide pipe (34) is rotatably connected to the outer side of the bottom of the spray frame (32). The spray guide pipe (34) is driven and controlled by a motor. A 135° bend is provided in the middle of the spray guide pipe (34). A spray fan (31) is installed at the bottom inside the spray guide pipe (34).

2. The aerosol simulation chamber with negative pressure protection according to claim 1, characterized in that: The top and bottom surfaces of the core module (1) are made of stainless steel. The side of the core module (1) near the power maintenance room (12) is made of a panel. The stainless steel frame of the core module (1) is connected to the top, bottom and panel of the core module (1) by welding.

3. The aerosol simulation chamber with negative pressure protection according to claim 1, characterized in that: The top of the core module (1) and the negative pressure protection zone (24) are both provided with air filter ports (3), and the air filter ports (3) are connected to the air filtration system (8) above them.

4. The aerosol simulation chamber with negative pressure protection according to claim 1, characterized in that: The air filtration system (8) includes an air conditioning unit duct (14), an air filtration device (16), an ozone device (27), and a valve (28). There are several air conditioning unit ducts (14). The ozone device (27) is installed on the top of the core module (1). The ozone device (27) is connected to the air filter port (3) on the top of the core module (1). There are two air filtration devices (16). One of the air filtration devices (16) is connected to the negative pressure protection zone (24) through the air conditioning unit duct (14). The other air filtration device (16) is connected to the constant temperature and humidity air conditioning unit (13) of the power maintenance room (12) through the air conditioning unit duct (14). The two air filtration devices (16) are connected through the air conditioning unit duct (14). The air filtration device (16) connected to the negative pressure protection zone is also connected to the ozone device (27) through the air conditioning unit duct (14).

5. The aerosol simulation chamber with negative pressure protection according to claim 1, characterized in that: An air communication valve (10) is provided on the side of the core module (1) adjacent to the negative pressure protection zone. The air communication valve (10) is located below the operation window (23).

6. The aerosol simulation chamber with negative pressure protection according to claim 1, characterized in that: A pressure gauge (21) is installed above the item transfer window (20), which is used to monitor the air pressure of the core module (1) and the negative pressure protection zone (24).

7. The aerosol simulation chamber with negative pressure protection according to claim 1, characterized in that: The top of the core module (1) is provided with a top compartment (22), and the air filtration system (8) is provided in the top compartment (22).

8. The aerosol simulation chamber with negative pressure protection according to claim 1, characterized in that: The live toxic wastewater system (30) consists of a sterilization tank, a mixing device, a pipeline pump and a breather. The sterilization tank is connected to the other components by welding and is sealed.

9. The aerosol simulation chamber with negative pressure protection according to claim 1, characterized in that: The walls of the core chamber (1) and the negative pressure protection zone (24) are equipped with circulating purification fans (17). The circulating purification fans (17) serve as a supplement to the stirring fan (4) to accelerate the aerosol concentration in the core chamber (1) to reach a uniform state.