Linear array gamma ray detector for intraoperative tumor detection and method of use

Abstract

The application relates to a linear array gamma ray detector for intraoperative tumor detection and a use method thereof, which comprises an exploration shell and a handle shell, N gamma ray detection units are arranged in a column and at equal intervals along the length direction in the exploration shell, and a gamma ray detection unit at a middle position is a position detection unit W; each gamma ray detection unit is matched with a collimator, the collimating direction is parallel to the axis direction of the handle shell, and the collimating direction of the collimator corresponding to the position detection unit W is coincident with the axis of the handle shell; a displacement sensor and an angle sensor are arranged in the handle shell, a plurality of indicator lamps are arranged on the exploration shell and correspond to the N gamma ray detection units, and the indicator lamps are used for indicating whether the corresponding gamma ray detection units have signal responses; the gamma ray detection units, the displacement sensor, the angle sensor and the indicator lamps are connected with a controller. The technical scheme has the advantages of simple structure, lightness, low cost and convenient use.

Description

Technical Field

[0001] This invention belongs to the technical field of gamma-ray detection instruments, specifically relating to a linear array gamma-ray detector for intraoperative tumor detection and its usage method. Background Technology

[0002] Malignant tumors are one of the major diseases threatening human health, with a high mortality rate. Surgical treatment remains the primary treatment method for most tumors.

[0003] Positron emission tomography (PET) is a non-invasive medical imaging technique and a relatively advanced clinical examination imaging technique in the field of nuclear medicine. It uses positron-emitting nuclides as tracers to understand tumor information by observing the uptake of tracers at the lesion site.

[0004] Existing PET equipment generally takes two forms: ring-shaped PET detectors and flat-panel PET detectors. Ring-shaped PET detectors are closed imaging systems with a near-ring-shaped structure, composed of multiple detector components, as shown in the attached diagram. Figure 1 As shown in the attached diagram. A flat-panel PET detector consists of a pair of stacked flat-panel detectors, each with an array of multiple detector heads. Figure 2 As shown.

[0005] The two PET devices mentioned above are large in size, making them difficult to use for tumor tracing during surgery, and there is currently no suitable tumor localization device for use in surgery. Summary of the Invention

[0006] The technical problem to be solved by the present invention is to overcome the shortcomings of the prior art and provide a linear array gamma-ray detector for intraoperative tumor detection and a method of using it.

[0007] To solve the above-mentioned technical problems, the technical solution of the present invention is as follows:

[0008] A linear array gamma ray detector for intraoperative tumor detection includes a detection housing, the top center of which is fixedly connected to a handle housing, and the bottom of the detection housing is used to contact the human skin.

[0009] The detection shell is equipped with N gamma-ray detection units, N=2n+1, n≥1; the N gamma-ray detection units are arranged in a row with equal spacing along the length of the detection shell, and the gamma-ray detection unit located in the middle position is the position detection unit W;

[0010] Each gamma-ray detection unit is equipped with a collimator. The collimator is used to guide gamma rays that meet the collimation direction to the corresponding gamma-ray detection unit. The collimation direction of the collimator is parallel to the axial direction of the handle housing, and the collimation direction of the collimator corresponding to the position detection unit W coincides with the axis of the handle housing.

[0011] The handle housing contains a displacement sensor and an angle sensor, which are used to sense the displacement and angle of the position detection unit W, respectively.

[0012] The detection housing is equipped with multiple indicator lights, each corresponding to N gamma-ray detection units, to indicate whether the corresponding gamma-ray detection unit has a signal response;

[0013] The gamma-ray detection unit, displacement sensor, angle sensor, and indicator lights are all connected to the controller.

[0014] Furthermore, the detection housing is provided with an indicator mark, which is used to guide the indicator light corresponding to the position detection unit W.

[0015] Furthermore, the spacing between adjacent collimators is 3mm to 5mm.

[0016] Furthermore, 10 ≤ n ≤ 15.

[0017] Furthermore, the surface of the probe shell that contacts the human skin is an arc surface.

[0018] Furthermore, the housing is equipped with a zeroing key, which is connected to the controller and is used to send a signal to the controller to reset the counts of the displacement sensor and angle sensor to zero.

[0019] A method for using a linear array gamma-ray detector for intraoperative tumor detection, as described above, includes the following steps:

[0020] Step 1: Hold the gamma-ray detector vertically and place the bottom arc surface of the probe housing against the human skin; then, move the gamma-ray detector horizontally along the width of the probe housing.

[0021] Step 2: When a gamma-ray detection unit receives ray γ1, the gamma-ray detection unit detects a tumor, and the controller controls the corresponding indicator light to emit an indicator light;

[0022] Step 3: Manually mark the location P1 on the human skin corresponding to the tumor, and then translate the gamma ray detector along the length of the detection shell to move the position detection unit W to position P1. When the indicator light corresponding to the position detection unit W emits an indicator light, the position detection unit W is located at position P1; stop moving the gamma ray detector, and at the same time operate the controller to reset the counts of the displacement sensor and angle sensor to zero.

[0023] Step 4: Tilt the handle housing at an angle θ, and then translate the γ-ray detector along the width of the detection housing. The indicator light of the corresponding indicator light of the position detection unit W will disappear.

[0024] Step 5: When the position detection unit W receives ray γ2, the corresponding indicator light of the position detection unit W emits an indicator light again. At this time, the γ-ray detector is located at position P2 on the split skin. The controller calculates the depth h of the tumor 200 relative to position P1 on the human skin 100 based on the data sent by the displacement sensor and angle sensor, where h = z + x / tanθ.

[0025] Where z is the vertical displacement transmitted by displacement sensor 7, x is the horizontal displacement transmitted by displacement sensor 7, and θ is the measured tilt angle transmitted by angle sensor 8.

[0026] The beneficial effects that this invention can achieve are: compared with the existing ring PET detector and flat panel PET detector, this technical solution has a simple structure, is lightweight, has low cost, and is easy to use. Attached Figure Description

[0027] Figure 1 This is a schematic diagram of a ring-shaped PET detector in the existing technology.

[0028] Figure 2 This is a schematic diagram of a flat-panel PET detector in existing technology.

[0029] Figure 3 This is a perspective view (a) of an embodiment of the present invention.

[0030] Figure 4 This is a perspective view (II) of an embodiment of the present invention.

[0031] Figure 5 This is the front view of an embodiment of the present invention.

[0032] Figure 6 This is a rear view of an embodiment of the present invention.

[0033] Figure 7 This is a schematic diagram of the internal structure of an embodiment of the present invention.

[0034] Figure 8 This is an application principle diagram of an embodiment of the present invention.

[0035] In the image: 100 - gamma ray detector, 200 - tumor, 300 - human epidermis;

[0036] 1-Probe housing, 2-Handle housing, 3-Merge line, 4-Indicator light, 5-Collimator, 6-Gamma ray detection unit, 7-Displacement sensor, 8-Angle sensor, 9-Indicator mark, 10-Zeroing key. Detailed Implementation

[0037] The present invention will now be described in further detail with reference to the accompanying drawings and specific embodiments.

[0038] like Figures 3-7 As shown, a linear array gamma ray detector 100 for intraoperative tumor detection includes a detection housing 1, the top center of the detection housing 1 is fixedly connected to the handle housing 2, the bottom of the detection housing 1 is used to contact the human skin 300, and the surface of the detection housing 1 that contacts the human skin 300 is an arc surface.

[0039] The detection housing 1 contains N gamma-ray detection units 6, where N = 2n + 1, n ≥ 1, and in this embodiment n = 14, therefore N = 29. The 29 gamma-ray detection units 6 are arranged in a row with equal spacing along the length of the detection housing 1, with the gamma-ray detection unit 6 located in the middle being the position detection unit W. Each gamma-ray detection unit 6 includes a scintillation crystal array and a photodetector. The scintillation crystal array receives gamma rays and generates scintillation light, which is transmitted to the photodetector, which converts the optical signal into an electrical signal. The structure of the gamma-ray detection unit 6 is existing technology and will not be described in detail here.

[0040] Each gamma-ray detection unit 6 is equipped with a collimator 5. The collimator 5 is used to guide gamma rays that meet the collimation direction to the corresponding gamma-ray detection unit 6, while gamma rays in other directions cannot reach the gamma-ray detection unit 6. The collimation direction of the collimator 5 is parallel to the axis of the handle housing 2, and the collimation direction of the collimator 5 corresponding to the position detection unit W coincides with the axis of the handle housing 2. The distance between adjacent collimators 5 is 3 mm.

[0041] The handle housing 2 is equipped with a displacement sensor 7 and an angle sensor 8, which are used to sense the displacement and angle of the position detection unit W, respectively.

[0042] The detection housing 1 is equipped with multiple indicator lights 4, each corresponding to one of the N gamma-ray detection units 6. These lights indicate whether the corresponding gamma-ray detection unit 6 has a signal response. When the gamma-ray detection unit 6 detects a tumor 200, the corresponding indicator light 4 emits an indicator light; when the gamma-ray detection unit 6 does not detect a tumor 200, the corresponding indicator light 4 does not emit an indicator light. The indicator light can change from green to red, from no light to light, or from a steady light to a flashing light.

[0043] The gamma-ray detection unit 6, displacement sensor 7, angle sensor 8, and indicator light 4 are all connected to the controller, and the corresponding connection lines are grouped together to form a merged line 3.

[0044] The housing 1 is equipped with an indicator mark 9, which is used to guide the indicator light 4 corresponding to the position detection unit W.

[0045] The probe housing 1 is equipped with a zeroing key 10, which is connected to the controller and is used to send a signal to the controller to reset the counts of the displacement sensor 7 and the angle sensor 8 to zero.

[0046] After injecting the radionuclide tracer drug De-99m into the human body, this embodiment was used to explore the location of tumor 200 in the human body.

[0047] The usage method of this embodiment includes the following steps:

[0048] (1) Hold the gamma-ray detector 100 vertically and place the bottom arc surface of the detection housing 1 against the human skin 300; then, move the gamma-ray detector 100 along the width of the detection housing 1.

[0049] (2) When a certain gamma-ray detection unit 6 receives ray γ1, the gamma-ray detection unit 6 detects tumor 200, and the controller controls the corresponding indicator light 4 to emit an indicator light.

[0050] (3) The location P1 on the human epidermis 100 corresponding to the artificially marked tumor 200 (e.g., Figure 8 (As shown), then the gamma-ray detector 100 is translated along the length of the detection housing 1, so that the position detection unit W is moved to position P1. When the indicator light 4 corresponding to the position detection unit W emits an indicator light, the position detection unit W is located at position P1. Stop moving the gamma-ray detector 100, and at the same time operate the controller to make the displacement sensor 7 and the angle sensor 8 count to zero. The operation method can be to input the count to zero command to the controller through the human-machine interaction device, or it can be to operate the zeroing key 10 to send a signal to the controller to make the displacement sensor 7 and the angle sensor 8 count to zero.

[0051] (3) Tilt the handle housing 2 at an angle θ, and then translate the γ-ray detector 100 along the width direction of the detection housing 1. The indicator light of the indicator light 4 corresponding to the position detection unit W disappears.

[0052] (4) When the position detection unit W receives ray γ2, the indicator light 4 corresponding to the position detection unit W emits an indicator light again. At this time, the γ-ray detector 100 is located at position P2 on the split skin 100 (e.g., Figure 8As shown in the figure, the controller calculates the depth h of the tumor 200 relative to the position P1 on the human skin 100 based on the data sent by the displacement sensor 7 and the angle sensor 8, thereby obtaining the exact position of the tumor 200 in the human body.

[0053] The data sent to the controller by displacement sensor 7 is the horizontal displacement x and the vertical displacement z. The data sent to the controller by angle sensor 8 is the measured tilt angle θ. The depth h of the tumor 200 at position P1 relative to the human skin 100 is:

[0054] h=z+x / tanθ

[0055] The principle is as follows Figure 8 As shown, h = z + h1, h1 = x / tanθ.

[0056] The surgeon can roughly determine the subcutaneous location of the tumor 200 by combining the detection results of the gamma ray detector 100.

[0057] Compared with existing ring PET detectors and flat panel PET detectors, this embodiment has a simple structure, is lightweight, low cost, and easy to use.

Claims

1. A linear array gamma-ray detector for intraoperative tumor detection, characterized in that: It includes a probe housing (1), the top center of the probe housing (1) is fixedly connected to the handle housing (2), and the bottom of the probe housing (1) is used to contact the human skin; The exploration shell (1) is provided with N γ-ray detection units (6), N=2n+1, n≥1; the N γ-ray detection units (6) are arranged in a row at equal intervals along the length of the exploration shell (1), and the γ-ray detection unit (6) located in the middle position is the position detection unit W; Each gamma-ray detection unit (6) is matched with a collimator (5). The collimator (5) is used to transmit gamma rays that meet the collimation direction to the corresponding gamma-ray detection unit (6). The collimation direction of the collimator (5) is parallel to the axial direction of the handle housing (2), and the collimation direction of the collimator (5) corresponding to the position detection unit W coincides with the axis of the handle housing (2). The handle housing (2) is equipped with a displacement sensor (7) and an angle sensor (8), which are used to sense the displacement and angle of the position detection unit W, respectively. The detection housing (1) is equipped with multiple indicator lights (4), which correspond to N gamma-ray detection units (6) respectively, and are used to indicate whether the corresponding gamma-ray detection unit (6) has a signal response; The gamma-ray detection unit (6), displacement sensor (7), angle sensor (8) and indicator light (4) are all connected to the controller; The probe housing (1) is provided with a zeroing key (10), which is connected to the controller and is used to send a signal to the controller so that the displacement sensor (7) and the angle sensor (8) count to zero.

2. The linear array gamma-ray detector for intraoperative tumor detection according to claim 1, characterized in that: The detection housing (1) is provided with an indicator mark (9), which is used to guide the indicator light (4) corresponding to the position detection unit W.

3. The linear array gamma-ray detector for intraoperative tumor detection according to claim 1, characterized in that: The spacing between adjacent collimators (5) is 3mm to 5mm.

4. The linear array gamma-ray detector for intraoperative tumor detection according to claim 1, characterized in that: 10≤n≤15。 5. The linear array gamma-ray detector for intraoperative tumor detection according to claim 1, characterized in that: The surface of the probe shell (1) that comes into contact with the human skin is an arc surface.

6. A method of using a linear array gamma-ray detector for intraoperative tumor detection according to any one of claims 1-5, characterized in that: Includes the following steps, Step 1: Hold the gamma-ray detector vertically and place the bottom arc surface of the detection housing (1) against the human skin (300); then, move the gamma-ray detector along the width of the detection housing (1). Step 2: When a certain gamma-ray detection unit (6) receives ray γ1, the gamma-ray detection unit (6) detects the tumor (200), and the controller controls the corresponding indicator light (4) to emit an indicator light; Step 3: Manually mark the position P1 on the human epidermis (300) corresponding to the tumor (200), and then translate the γ-ray detector along the length direction of the probe housing (1) so that the position detection unit W moves to position P1. When the indicator light (4) corresponding to the position detection unit W emits an indicator light, the position detection unit W is located at position P1; stop moving the γ-ray detector, and at the same time operate the controller to make the displacement sensor (7) and angle sensor (8) count to zero; Step 4: Tilt the handle housing (2) at an angle θ, and then translate the γ-ray detector along the width direction of the probe housing (1). The indicator light of the corresponding indicator light (4) of the position detection unit W disappears. Step 5: When the position detection unit W receives ray γ2, the corresponding indicator light (4) of the position detection unit W emits an indicator light again. At this time, the γ-ray detector is located at position P2 on the human skin (300). The controller calculates the depth h of the tumor (200) relative to position P1 on the human skin (300) based on the data sent by the displacement sensor (7) and the angle sensor (8), where h = z + x / tanθ. Where z is the vertical displacement transmitted by the displacement sensor (7), x is the horizontal displacement transmitted by the displacement sensor (7), and θ is the measured tilt angle transmitted by the angle sensor (8).

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