Methods, apparatus, and storage media for determining tissue operation parameters based on detection devices.

Abstract

This invention discloses a method, apparatus, and storage medium for determining tissue operation parameters based on a detection device. The detection device includes an elastic detection probe and a pressure detection device connected to the elastic detection probe. The pressure detection device includes a pressure measuring device and a pressure sensing device. The pressure sensing device includes a liquid chamber for containing liquid, and the pressure measuring device is connected to the liquid chamber. The method includes: when the elastic detection probe presses against the skin surface of the target tissue area through the pressure sensing device, the pressure measuring device detects the hydraulic pressure in the liquid chamber; when the hydraulic pressure meets a preset pressure range, the elastic detection probe collects ultrasound imaging data and shear wave elastography data of the target tissue and other surrounding tissues; based on the ultrasound imaging data and shear wave elastography data, the operation parameters for operating on the target tissue are determined. The determined operation parameters have high accuracy, thereby improving operational precision.

Description

Technical Field

[0001] This invention relates to the field of biomedicine, and more specifically to a method, apparatus, and storage medium for determining tissue operating parameters based on a detection device. Background Technology

[0002] Depending on the nature of the tumor tissue, different treatment methods can be adopted. For example, malignant tumors can be treated with surgical resection, while benign tumors can be treated conservatively with medication. However, regardless of the method used to treat the tumor tissue, it is necessary to ensure the precision of the procedure. For example, when removing tumor tissue, it is necessary to ensure that the tissue is completely removed.

[0003] Currently, ultrasound equipment is typically used to guide manipulation of tumor tissues. However, the imaging data of tumor tissues may be inaccurate, which means that the precision of tumor tissue manipulation needs to be improved. Summary of the Invention

[0004] In view of this, embodiments of the present invention provide a method, a parameter determination device, an electronic device, and a computationally readable storage medium for determining tissue operation parameters based on a detection device. The determined operation parameters have high accuracy, thereby improving operation accuracy.

[0005] This invention provides a method for determining tissue operation parameters based on a detection device, the detection device comprising an elastic detection probe and a pressure detection device connected to the elastic detection probe, the pressure detection device comprising a pressure measuring device and a pressure sensing device, the pressure sensing device comprising a liquid chamber for containing liquid, the pressure measuring device being connected to the liquid chamber, and the method comprising:

[0006] When the elastic detection probe presses the skin surface of the target tissue area through the pressure sensing device, the hydraulic pressure of the liquid chamber is detected by the pressure measuring device;

[0007] When the hydraulic pressure meets the preset pressure range, the elastic detection probe is used to collect ultrasound imaging data and shear wave elastic imaging data of the target tissue and other tissues around the target tissue.

[0008] Based on the ultrasound imaging data and the shear wave elastography data, the operating parameters for operating on the target tissue are determined.

[0009] In some embodiments, the method further includes: during the process of the elasticity detection probe pressing the skin surface through the pressure sensing device, acquiring quasi-static elastography data of the target tissue and other surrounding tissues through the elasticity detection probe;

[0010] Specifically, determining the operating parameters for operating on the target tissue based on the ultrasound imaging data and the shear wave elastography data includes: determining the operating parameters for operating on the target tissue based on the ultrasound imaging data, the shear wave elastography data, and the quasi-static elastography data.

[0011] In some embodiments, the operation on the target tissue includes marking the target tissue, and the operation parameters include the marking location;

[0012] Based on the ultrasound imaging data, the shear wave elastography data, and the quasi-static elastography data, the operating parameters for manipulating the target tissue are determined, including:

[0013] Based on at least one of the ultrasound imaging data, the shear wave elastography data, and the quasi-static elastography data, the edge contour features of the target tissue are obtained, and based on the edge contour features, a first alternative marking position is obtained when marking the target tissue.

[0014] Based on the ultrasound imaging data, the shear wave elastography data, and the quasi-static elastography data, the soft and hard characteristic distribution information of the target tissue is obtained, and based on the soft and hard characteristic distribution information, the locations where the softness and hardness exceed a preset threshold are used as second candidate marker locations, wherein the soft and hard characteristic distribution information represents the softness and hardness of the target tissue at different locations;

[0015] Based on the first candidate marker position and the second candidate marker position, a marker position for marking the target tissue is determined.

[0016] In some embodiments, the distribution information of the soft and hard properties of the target tissue is obtained based on the ultrasound imaging data, the shear wave elastography data, and the quasi-static elastography data, including:

[0017] By fusing the shear wave elastography data and the quasi-static elastography data, the elastic distribution information of the target tissue is obtained;

[0018] The density distribution and composition distribution information of the target tissue are obtained through the ultrasound imaging data.

[0019] The soft and hard property distribution information is determined by the density distribution information, the composition distribution information, and the elasticity distribution information.

[0020] In some embodiments, a pressure-sensitive device is disposed between the liquid chamber and the pressure measuring device;

[0021] The detection of hydraulic pressure in the liquid chamber includes:

[0022] The pressure-sensitive characteristic parameter value of the pressure-sensitive device is detected, and the hydraulic pressure in the liquid chamber is determined based on the detected result.

[0023] In some embodiments, the pressure-sensing device further includes a first contact layer located on one side of the liquid chamber and a second contact layer located on the other side of the liquid chamber, wherein the first contact layer is used to contact the elastic detection probe and the second contact layer is used to contact the skin surface of the area where the target tissue is located;

[0024] Before acquiring the ultrasonic imaging data and the shear wave elastography data using the elasticity detection probe, the method further includes:

[0025] The first acoustic impedance of the first contact layer and the second acoustic impedance of the second contact layer are respectively adapted to the liquid in the liquid cavity.

[0026] In some embodiments, the operation on the target tissue includes marking the target tissue, and the operation parameters include the marking location;

[0027] Based on the ultrasound imaging data and the shear wave elastography data, determine the operating parameters for manipulating the target tissue, including:

[0028] Based on the ultrasound imaging data and / or the shear wave elastography data, the edge contour features of the target tissue are obtained, and based on the edge contour features, a first alternative marking position is obtained when marking the target tissue.

[0029] Based on the ultrasound imaging data and the shear wave elastography data, the soft and hard characteristic distribution information of the target tissue is obtained, and based on the soft and hard characteristic distribution information, the locations where the softness and hardness exceed a preset threshold are used as second candidate marker locations, wherein the soft and hard characteristic distribution information represents the softness and hardness of the target tissue at different locations;

[0030] Based on the first candidate marker position and the second candidate marker position, a marker position for marking the target tissue is determined.

[0031] In some embodiments, the distribution information of the soft and hard properties of the target tissue is obtained based on the ultrasound imaging data and the shear wave elastography data, including:

[0032] The absolute elastic distribution information of the target tissue is obtained through the shear wave elastography data.

[0033] The density distribution and composition distribution information of the target tissue are obtained through the ultrasound imaging data.

[0034] The soft and hard property distribution information is obtained by combining the absolute elasticity distribution information, the density distribution information, and the composition distribution information.

[0035] Another aspect of the present invention provides a parameter determination device for determining tissue operation parameters based on a detection device, the detection device comprising an elastic detection probe and a pressure detection device connected to the elastic detection probe, the pressure detection device comprising a pressure measuring device and a pressure sensing device, the pressure sensing device comprising a liquid chamber for containing liquid, the pressure measuring device being connected to the liquid chamber, the device comprising:

[0036] A hydraulic detection module is used to detect the hydraulic pressure of the liquid chamber by means of the pressure measuring device when the elastic detection probe presses the skin surface of the target tissue area through the pressure sensing device.

[0037] The data acquisition module is used to acquire ultrasound imaging data and shear wave elastography data of the target tissue and other tissues surrounding the target tissue using the elastic detection probe when the hydraulic pressure meets the preset pressure range.

[0038] The determination module is used to determine the operating parameters when operating on the target tissue based on the ultrasound imaging data and the shear wave elastography data.

[0039] In another aspect, the present invention provides a computer-readable storage medium for storing a computer program that, when executed by a processor, implements the method described above.

[0040] In another aspect, the present invention provides an electronic device comprising a processor and a memory, the memory being used to store a computer program which, when executed by the processor, implements the method described above.

[0041] In some embodiments of this application, the hydraulic pressure in the liquid chamber is detected by a pressure measuring device. When the hydraulic pressure matches a preset pressure range, ultrasonic imaging data and shear wave elastography data of the target tissue and other tissues surrounding the target tissue are collected. Then, the ultrasonic imaging data and shear wave elastography data are used to obtain the operating parameters for operating on the target tissue. In this way, on the one hand, by collecting ultrasonic imaging data and shear wave elastography data when the actual hydraulic pressure meets the preset pressure range, the operator can collect data under the same standard, ensuring the consistency of the collected data and thus guaranteeing the accuracy and stability of the obtained operating parameters. On the other hand, compared with some technologies that rely solely on ultrasonic equipment to guide tissue operation, this application determines the operating parameters for tissue operation based on both ultrasonic imaging data and shear wave elastography data. Therefore, the determined operating parameters have high accuracy, which greatly improves the precision of the operation. Attached Figure Description

[0042] The features and advantages of the invention will be more clearly understood by referring to the accompanying drawings, which are schematic and should not be construed as limiting the invention in any way. In the drawings:

[0043] Figure 1 A schematic diagram of the structure of a detection device provided in one embodiment of this application is shown;

[0044] Figure 2 This illustration shows a detection schematic diagram provided in one embodiment of the present application;

[0045] Figure 3 A schematic diagram of a pressure transmission device according to an embodiment of this application is shown;

[0046] Figure 4 A schematic diagram of a pressure transmission device according to another embodiment of this application is shown;

[0047] Figure 5 A flowchart illustrating a method for determining tissue operating parameters based on a detection device according to an embodiment of this application is shown.

[0048] Figure 6 A flowchart illustrating a marker position determination method according to an embodiment of this application is shown;

[0049] Figure 7 This invention provides a schematic diagram of the functional modules of a parameter determination device based on a detection device for determining tissue operation parameters, according to an embodiment of this application.

[0050] Figure 8 A schematic diagram of the structure of an electronic device provided in one embodiment of this application is shown. Detailed Implementation

[0051] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0052] The target tissue can be tumor tissue, benign lesion tissue, etc. Treatment of the target tissue typically involves procedures such as excision and labeling. Taking tumor tissue as an example, the tumor tissue and surrounding tissues can include the organ containing the tumor and the surrounding muscle tissue, depending on the location and size of the tumor. Taking breast tumors as an example, the target tissue and surrounding tissues can include the breast and the surrounding muscle tissue.

[0053] This application provides a method for determining tissue operation parameters based on a detection device, which can improve operational accuracy. Before introducing the method of this application, the detection device will be described first.

[0054] Please see Figure 1 This is a schematic diagram of the structure of a detection device 100 provided in one embodiment of this application. Figure 1 In this embodiment, the detection device 100 includes an elastic detection probe 14 and a pressure detection device 11, which are connected together. In some embodiments, the elastic detection probe 14 can be detachably connected to the pressure detection device 11. Specifically, the elastic detection probe 14 can be connected to the pressure detection device 11 via an opening and closing locking device, or the pressure detection device 11 can be designed as a slot that matches the elastic detection probe 14 for connection. In other embodiments, the elastic detection probe 14 and the pressure detection device 11 can also be an integrated design.

[0055] The pressure detection device 11 includes a pressure measuring device 112 and a pressure sensing device 111. The pressure sensing device 111 includes a liquid chamber 1112 for containing liquid. The pressure measuring device 112 is connected to the liquid chamber 1112.

[0056] See also Figure 2 This is a schematic diagram of a detection method provided in one embodiment of this application. Figure 2During the detection process, the elastic detection probe 14 presses against the skin surface of the target tissue area via the pressure sensing device 111. The liquid cavity 1112 is located between the elastic detection probe 14 and the skin surface. The elastic detection probe 14 presses against the liquid cavity 1112, and the liquid cavity 1112 transmits the pressure from the elastic detection probe 14 to the skin surface. This achieves pressure on the skin surface. Simultaneously, the elastic detection probe 14 emits ultrasonic signals. These signals pass through the liquid within the liquid cavity 1112 and are transmitted through the skin surface to the target tissue and surrounding tissues. Echo signals generated by the reflection of the ultrasonic signals by the surrounding tissues also return to the elastic detection probe 14 via the liquid within the liquid cavity 1112. The elastic detection probe 14 sends the received echo signals to the receiving module 13, which then sends them to the control module 16. The control module 16 processes the echo signals to obtain ultrasound imaging data and elasticity imaging data of the target tissue and surrounding tissues. Specific details of the process are described in detail later and will not be repeated here.

[0057] When the elastic detection probe 14 presses against the liquid cavity 1112, the liquid cavity 1112 deforms, and the liquid inside is compressed, causing a corresponding change in hydraulic pressure. Hydraulic pressure represents the pressure exerted by the liquid within the liquid cavity 1112. The hydraulic pressure in the liquid cavity 1112 is positively correlated with the pressing force of the elastic detection probe 14; that is, the greater the pressing force of the elastic detection probe 14, the greater the hydraulic pressure within the liquid cavity 1112. By detecting the hydraulic pressure within the liquid cavity 1112, the pressing force applied by the elastic detection probe 14 to the skin surface through the liquid cavity 1112 can be detected.

[0058] See Figure 2 In this embodiment, the pressure-sensing device 111 further includes a first contact layer 1111 located on one side of the liquid cavity 1112 and a second contact layer 1113 located on the other side of the liquid cavity 1112. The first contact layer 1111 is used to contact the probe surface corresponding to the ultrasonic transducer in the elastic detection probe 14, and the second contact layer 1113 is used to contact the skin surface of the target tissue area. The first contact layer 1111 and the second contact layer 1113 may have deformable characteristics. When the elastic detection probe 14 presses the liquid cavity 1112, the first contact layer 1111 and the second contact layer 1113 may deform together with the liquid cavity 1112.

[0059] See also Figure 1 In some embodiments, the pressure detection device 11 further includes a liquid injection device 113 and a connecting device 114. The liquid injection device 113 includes a liquid injection port PC, which is connected to the liquid chamber 1112 via the connecting device 114. The liquid injection device 113 injects liquid into the liquid chamber 1112 through the liquid injection port PC and the connecting device 114.

[0060] The connecting device 114 may further include an isolation device 1141. When the isolation device 1141 is in the first state, the injection device 113 is connected to the liquid chamber 1112 through the injection port PC, and the injection device 113 injects liquid into the liquid chamber 1112; when the isolation device 1141 is in the second state, the injection device 113 is isolated from the liquid chamber 1112, and the injection device 113 stops injecting liquid into the liquid chamber 1112.

[0061] In this embodiment, the isolation device 1141 includes a valve.

[0062] In some embodiments, the pressure measuring device 112 includes a first port PA, and the liquid chamber 1112 includes a second port PB. The first port PA is connected to the second port PB via a connecting device 114. The pressure measuring device 112 detects the hydraulic pressure in the liquid chamber 1112 through the first port PA.

[0063] Please see Figure 3 This is a schematic diagram illustrating the principle of a pressure measuring device 112 provided in one embodiment of this application. The pressure measuring device 112 may include a pressure-sensitive resistor and a standard pressure chamber. The pressure-sensitive resistor can be connected between the input pressure chamber and the standard pressure chamber. The input pressure chamber can refer to the liquid chamber 1112 mentioned earlier. The standard pressure chamber can refer to a device that outputs a standard pressure. The standard pressure output by the standard pressure chamber can be maintained at a known fixed value. The pressure difference between the input pressure chamber and the standard pressure chamber is different, resulting in different resistance values ​​for the pressure-sensitive resistor. Thus, by detecting the resistance of the pressure-sensitive resistor, the pressure difference between the input pressure chamber and the standard pressure chamber can be indirectly detected. Furthermore, since the pressure output by the standard pressure chamber is known, the hydraulic pressure in the liquid chamber 1112 can be detected based on the pressure output by the standard pressure chamber and the pressure difference between the input pressure chamber and the standard pressure chamber.

[0064] Specifically, the pressure measuring device 112 may further include a power supply, a matching resistor, and a detection circuit (not shown). The matching resistor and the piezoresistive resistor can be connected in series between the positive and negative terminals of the power supply to form a current path. The detection circuit is connected to the piezoresistive resistor. The piezoresistive resistor and the matching resistor divide the voltage output by the power supply. When the resistance of the piezoresistive resistor changes, the voltage across the piezoresistive resistor also changes accordingly. Based on this principle, the detection circuit can detect the voltage value across the piezoresistive resistor. Based on the detected voltage value, the resistance of the piezoresistive resistor can be determined, and thus the hydraulic pressure in the liquid chamber 1112 can be determined. In this way, it is equivalent to detecting the pressure applied to the skin surface by the elastic detection probe 14 through the liquid chamber 1112.

[0065] Please continue reading Figure 4 This is a schematic diagram of the pressure measuring device 112 provided in another embodiment of this application. Figure 4and Figure 3 They are basically similar, with the main difference being that the standard pressure chamber side has a first insulating sheet 1120, while the input pressure chamber side has a second insulating sheet 1121, with a dielectric material between the first and second insulating sheets 1120 and 1121. The pressure difference between the input pressure chamber (hydraulic) and the standard pressure chamber is different, and therefore the capacitance between the first and second insulating sheets 1120 and 1121 is different. Thus, detecting the capacitance between the first and second insulating sheets 1120 is equivalent to detecting the pressure difference between the input and standard pressure chambers.

[0066] Please continue reading Figure 1 In some embodiments, the detection device 100 further includes a transmitting module 12, a receiving module 13, a control module 16, and an interaction module 17. The transmitting module 12 sends different first electrical signals to the elastic detection probe 14, which converts the first electrical signals into corresponding ultrasonic waves. After receiving the echo signal of the ultrasonic waves, the elastic detection probe 14 converts the echo signal into a second electrical signal and sends the second electrical signal to the receiving module 13. The control module 16 is specifically used to: control the transmitting module 12 to transmit corresponding signals; control the receiving module 13 to receive corresponding signals; control the elastic detection probe to transmit and receive signals; receive the hydraulic pressure detected by the pressure detection device 11 and the second electrical signal provided by the receiving module 13, and process the second electrical signal to obtain relevant imaging data; send the detected hydraulic pressure to the interaction module 17 for display; and receive information input by the operator through the interaction module 17.

[0067] Please see Figure 5 This is a flowchart illustrating a method for determining tissue operation parameters based on a detection device, provided as an embodiment of this application. Figure 5 The method shown can be applied to Figure 1 Control module 16 in the middle.

[0068] Figure 5 In this context, methods for determining tissue operating parameters may include the following steps:

[0069] Step S51: When the elastic detection probe presses the skin surface of the target tissue area through the pressure sensing device, the hydraulic pressure of the liquid chamber is detected by the pressure measuring device.

[0070] like Figure 3 and Figure 4 A pressure-sensitive device (such as a pressure-sensitive resistor) can be installed between the liquid chamber and the pressure measuring device. The pressure-sensitive device has pressure-sensitive characteristic parameters (such as resistance). The value of the pressure-sensitive characteristic parameters changes with the hydraulic pressure in the liquid chamber. When detecting the hydraulic pressure, the value of the pressure-sensitive characteristic parameters of the pressure-sensitive device can be detected, and the hydraulic pressure in the liquid chamber can be determined based on the detected result.

[0071] Step S52: When the hydraulic pressure meets the preset pressure range, use the elastic detection probe to collect ultrasound imaging data and shear wave elastic imaging data of the target tissue and other tissues around the target tissue.

[0072] In some embodiments, the preset pressure ranges for different target tissues may be the same or different. However, due to differences in skin density, fat thickness, etc., in different parts of the human body, the appropriate pressure applied by the elasticity detection probe to the corresponding skin surface at different locations is also different. Therefore, preferably, target tissues in different locations can have their own corresponding preset pressure ranges. For example, when acquiring imaging data of the thyroid gland and other tissues surrounding the thyroid gland, the preset pressure range between the elasticity detection probe and the skin surface is preferably between 0 and 3 N.

[0073] In some embodiments, the preset pressure range may be selected or input by the operator through the aforementioned interactive module, or it may be obtained from pre-stored data; this application does not limit this.

[0074] In some other embodiments, a correspondence between each target tissue and a preset pressure range can be pre-defined. When detecting the target tissue and other tissues around it, the corresponding preset pressure range is obtained based on the target location of the target tissue.

[0075] In some embodiments, before acquiring ultrasound imaging data and shear wave elastography data through the elasticity detection probe, the first acoustic impedance of the first contact layer located on one side of the liquid cavity and the second acoustic impedance of the second contact layer located on the other side of the liquid cavity can be adapted to the liquid in the liquid cavity, so that the ultrasound signal can enter the tissue as much as possible.

[0076] Specifically, the elasticity detection probe can acquire ultrasound imaging data and shear wave elastography data of the target tissue and surrounding tissues based on the following method: The elasticity detection probe first emits a high-intensity first ultrasound signal to the target tissue and surrounding tissues, focusing to generate acoustic radiation force, thereby forming a shear wave within the target tissue and surrounding tissues, which then propagates; then the elasticity detection probe emits a second ultrasound signal to the target tissue and surrounding tissues, and receives the corresponding ultrasound echo signal, wherein the second ultrasound signal is used to track the propagation of the shear wave. Based on the received ultrasound echo signal, ultrasound imaging data and shear wave elastography data of the target tissue and surrounding tissues can be acquired.

[0077] Step S53: Determine the operating parameters for operating on the target tissue based on the ultrasound imaging data and shear wave elastography data.

[0078] Based on the descriptions of steps S51 and S52, it can be understood that this application acquires ultrasonic imaging data and shear wave elastic imaging data when the hydraulic pressure meets a preset pressure range. This standardizes the pressing pressure applied by different operators during imaging data acquisition, ensuring that all imaging data are acquired under the same pressure standard. Therefore, the consistency of the obtained imaging data is high, which in turn leads to high accuracy and stability of the determined operating parameters.

[0079] In other embodiments, the method for determining tissue operating parameters further includes:

[0080] During the process of the elasticity detection probe pressing the skin surface through the pressure sensing device, quasi-static elasticity imaging data of the target tissue and other surrounding tissues are collected by the elasticity detection probe.

[0081] Step S53, which involves determining the operating parameters for operating on the target tissue based on ultrasound imaging data and shear wave elastography data, includes: determining the operating parameters for operating on the target tissue based on ultrasound imaging data, shear wave elastography data, and quasi-static elastography data.

[0082] Quasi-static elastography data represents the relative elasticity of the target tissue and surrounding tissues at different locations. This data is collected when the pressure applied to the skin surface is adjusted, before reaching a preset pressure range. Specifically, as the elasticity detection probe adjusts the pressure through upward or downward movements, it emits a third ultrasonic signal to the target tissue and surrounding tissues and receives the echo signal. Based on the echo signal, a quasi-static elastography image of the target tissue and surrounding tissues can be obtained. Because the quasi-static elastography image contains information about quasi-static elastography parameters, quasi-static elasticity data of the target tissue and surrounding tissues can be obtained from it.

[0083] In this embodiment, quasi-static elastography data is simultaneously acquired during the pressure adjustment phase before obtaining ultrasound imaging data and shear wave elastography data. This allows for the acquisition of multiple elastography data sets in a single detection process, resulting in highly efficient data acquisition. Furthermore, the operational parameters of the target tissue can be determined based on the acquired multiple imaging data sets, which not only broadens the methods for determining operational parameters but also further improves the accuracy of the determined operational parameters.

[0084] In some embodiments, the operation performed on the target tissue includes marking the target tissue, and the operation parameters include the marking location. See also Figure 6This is a flowchart illustrating a marker position determination method provided in one embodiment of this application.

[0085] Step S61: Based on ultrasound imaging data and / or shear wave elastography data, obtain the edge contour features of the target tissue, and based on the edge contour features, obtain the first alternative marking position when marking the target tissue.

[0086] Both ultrasound imaging data and shear wave elastography data can include edge contour information of the target tissue. Therefore, the edge contour features of the target tissue can be extracted from both data separately. To ensure the accuracy of the results, the edge contour features extracted from the two types of data can be fused according to certain weights to obtain the final edge contour features of the target tissue.

[0087] Of course, it is understandable that ultrasound imaging data and shear wave elastography data can be fused, and the final edge contour features of the target tissue can be extracted based on the fused data.

[0088] In some embodiments, the presence or absence of a protrusion on the edge contour of the target tissue can be determined based on edge contour features. If a protrusion exists on the edge contour, the location of at least a portion of the protrusion can be used as a first candidate marker location. If no protrusion exists on the edge contour, a first candidate marker location can be determined at preset intervals on the edge contour.

[0089] Step S62: Based on the ultrasound imaging data and shear wave elastography data, obtain the soft and hard characteristic distribution information of the target tissue, and based on the soft and hard characteristic distribution information, use the locations where the softness and hardness exceed a preset threshold as the second candidate marker locations, wherein the soft and hard characteristic distribution information represents the softness and hardness of the target tissue at different locations.

[0090] Specifically, absolute elasticity distribution information of the target tissue can be obtained through shear wave elastography data, and density and composition distribution information can be obtained through ultrasound imaging data. Finally, the soft and hard property distribution information can be obtained through the absolute elasticity distribution, density distribution, and composition distribution information. The absolute elasticity distribution information characterizes the absolute elasticity at different locations within the target tissue, and can be represented by parameters such as elastic modulus, shear wave velocity, and elastic modulus distribution characteristics. The compositional distribution information characterizes the constituent substances at different locations within the target tissue. The density distribution information characterizes the density at different locations within the target tissue. These constituent substances can refer to substances such as fat, protein, and water, as well as their content.

[0091] Since elasticity, composition, and density can all reflect the hardness or softness of a tissue, the distribution information of the hardness or softness characteristics of a target tissue can be obtained by using its absolute elasticity distribution, composition distribution, and density distribution information. Specifically, different distribution information at the same location within the target tissue can be fused to obtain the hardness or softness at that location. Based on this method, the hardness or softness at various locations within the target tissue can be obtained, thus yielding the distribution information of the target tissue's hardness or softness characteristics.

[0092] In this embodiment, the preset threshold for softness / hardness can be set based on actual conditions. Locations in the target tissue where the softness / hardness exceeds the preset threshold may be locations that require continuous observation. Therefore, these locations need to be marked as candidate locations to be labeled, so as to facilitate the observation of these locations in the target tissue.

[0093] Step S63: Based on the first alternative marker position and the second alternative marker position, determine the marker position for marking the target tissue.

[0094] Specifically, in some embodiments, each first candidate marker position and each second candidate marker position can both serve as a marker position. Thus, based on each marker position, the location of the organization of interest can be accurately determined.

[0095] In some embodiments, a marker location can be determined within an area containing multiple closely spaced candidate marker locations. For example, if first candidate marker location A and second candidate marker location B are close to each other and can be marked using a single marker, then the midpoint between first candidate marker location A and second candidate marker location B can be used as the marker location. After marking this midpoint, the organizational structure of first candidate marker location A and second candidate marker location B can be viewed based on this marker location. This achieves the goal of reducing the number of marker locations.

[0096] In some embodiments, a tag clip may be placed at each tag location to facilitate long-term tracking of the target tissue based on the tag location. Before placing the tag clip at the tag location, at least one of the following processes may be performed on the tag clip:

[0097] Optionally, the surface of the marker clip can be smoothed or coated to allow it to reflect more ultrasound waves than the target tissue. This allows for effective differentiation between the marker clip and the target tissue during ultrasonic testing, based on the ultrasound echo data, thus determining the location of the target tissue.

[0098] Optionally, the marker clip may be treated with a biocompatible substance to make it compatible with the target tissue.

[0099] Optionally, the marker clips are sterilized to prevent infection of the target tissue at the marking location.

[0100] Optionally, the marker clip is designed with a specific shape so that its location can be determined based on the specific shape when performing ultrasound examination on the target tissue.

[0101] In other embodiments, determining the marker location may include the following steps:

[0102] Step S71: Based on at least one of ultrasound imaging data, shear wave elastography data, and quasi-static elastography data, obtain the edge contour features of the target tissue, and based on the edge contour features, obtain the first alternative marking position when marking the target tissue.

[0103] Similar to step S61, ultrasound imaging data, shear wave elastography data, and quasi-static elastography data can each include edge contour information of the target tissue. Therefore, the edge contour features of the target tissue can be extracted from the ultrasound imaging data, shear wave elastography data, and quasi-static elastography data. In this embodiment, quasi-static elastography data is also considered when determining the edge contour features of the target tissue, which makes the extracted edge contour features more accurate.

[0104] Step S72: Based on ultrasound imaging data, shear wave elastography data and quasi-static elastography data, obtain the soft and hard characteristic distribution information of the target tissue, and based on the soft and hard characteristic distribution information, use the locations where the softness and hardness exceed a preset threshold as the second candidate marker locations, wherein the soft and hard characteristic distribution information represents the softness and hardness of the target tissue at different locations.

[0105] Step S72 is basically similar to step S62, the main difference being that quasi-static elastography data of the target tissue is considered when determining the softness or hardness of the target tissue. As described above, quasi-static elastography data can represent the relative elasticity of different locations within the target tissue. Since relative elasticity is also a type of elasticity, and its magnitude is related to the degree of softness or hardness, quasi-static elastography data can also be used to assess the softness or hardness of the tissue.

[0106] Specifically, based on ultrasound imaging data, shear wave elastography data, and quasi-static elastography data, the distribution information of the soft and hard properties of the target tissue can be obtained, which may include:

[0107] 1) It can fuse shear wave elastography data and quasi-static elastography data to obtain elastic distribution information of the target tissue.

[0108] Based on the above description, it can be seen that shear wave elastography data can characterize the absolute elasticity at different locations of the target tissue, while quasi-static elastography data can represent the relative elasticity at different locations of the target tissue. Relative and absolute elasticity assess the elasticity of the target tissue from different perspectives. Therefore, shear wave elastography data and quasi-static elastography data can be fused to obtain the final elasticity distribution information of the target tissue. Specifically, the relative and absolute elasticities at the same location of the target tissue can be fused to obtain the elasticity at that location. The elasticity at different locations of the target tissue constitutes the elasticity distribution information of the target tissue, resulting in more accurate elasticity distribution information. Relative elasticity can be represented by parameters such as strain rate, strain ratio, and strain distribution characteristics.

[0109] 2) Obtain density and composition distribution information of the target tissue through ultrasound imaging data.

[0110] For details regarding density distribution information and composition distribution information, please refer to step S62 above; they will not be repeated here.

[0111] 3) Determine the distribution information of soft and hard properties by using density distribution information, composition distribution information, and elasticity distribution information.

[0112] This step is similar to step S62 above, and will not be repeated here.

[0113] Step S73: Based on the first alternative marker position and the second alternative marker position, determine the marker position for marking the target tissue.

[0114] This step is similar to step S63 above, and will not be repeated here.

[0115] In summary, in some embodiments of this application, the hydraulic pressure in the liquid chamber is detected by a pressure measuring device. When the hydraulic pressure matches a preset pressure range, ultrasonic imaging data and shear wave elastography data of the target tissue and other tissues surrounding the target tissue are collected. Then, based on the ultrasonic imaging data and shear wave elastography data, the operating parameters for operating on the target tissue are obtained. This approach ensures that, on the one hand, by collecting ultrasonic imaging data and shear wave elastography data under the same standard when the actual hydraulic pressure matches the preset pressure range, the operator can collect data under the same standard, guaranteeing the consistency of the collected data and thus ensuring the accuracy and stability of the obtained operating parameters. On the other hand, compared to some technologies that rely solely on ultrasonic equipment to guide tissue operation, this application determines the operating parameters for tissue operation based on both ultrasonic imaging data and shear wave elastography data. Therefore, the determined operating parameters have high accuracy, which greatly improves the precision of the operation.

[0116] Please see Figure 7This is a schematic diagram of the functional modules of a parameter determination device based on a detection device for determining tissue operation parameters, provided in one embodiment of this application. The parameter determination device includes:

[0117] The hydraulic detection module is used to detect the hydraulic pressure in the fluid chamber by a pressure measuring device when the elastic detection probe presses the skin surface of the target tissue area through the pressure sensing device.

[0118] The data acquisition module is used to acquire ultrasound imaging data and shear wave elastic imaging data of the target tissue and other tissues around the target tissue using an elastic detection probe when the hydraulic pressure meets the preset pressure range.

[0119] The determination module is used to determine the operating parameters when operating on the target tissue based on ultrasound imaging data and shear wave elastography data.

[0120] Please see Figure 8 This is a schematic diagram of the structure of an electronic device provided in one embodiment of this application. The electronic device includes a processor and a memory. The memory stores a computer program, which, when executed by the processor, implements the aforementioned operation method.

[0121] Memory, as a non-transitory computer-readable storage medium, can be used to store non-transitory software programs, non-transitory computer-executable programs, and modules, such as the program instructions / modules corresponding to the methods in the embodiments of this invention. The processor executes various functional applications and data processing by running the non-transitory software programs, instructions, and modules stored in the memory, thereby implementing the methods described in the above embodiments.

[0122] Although embodiments of the invention have been described in conjunction with the accompanying drawings, those skilled in the art can make various modifications and variations without departing from the spirit and scope of the invention, and such modifications and variations all fall within the scope defined by the appended claims.

Claims

1. A method for determining tissue operation parameters based on a detection device, characterized in that, The detection device includes an elastic detection probe and a pressure detection device connected to the elastic detection probe. The pressure detection device includes a pressure measuring device and a pressure sensing device. The pressure sensing device includes a liquid chamber for containing liquid. The pressure measuring device is connected to the liquid chamber. The method includes: When the elastic detection probe presses the skin surface of the target tissue area through the pressure sensing device, the elastic detection probe collects quasi-static elastography data of the target tissue and other surrounding tissues, and the pressure measuring device detects the hydraulic pressure of the fluid chamber. The quasi-static elastography data is obtained by emitting a third ultrasonic signal to the target tissue and other surrounding tissues and receiving the corresponding echo signal when the pressure on the skin surface has not yet met the preset pressure range, and when the pressure is adjusted by the lifting or pressing action of the elastic detection probe. When the hydraulic pressure meets the preset pressure range, the elastic detection probe is used to collect ultrasound imaging data and shear wave elastic imaging data of the target tissue and other tissues around the target tissue. Based on the ultrasound imaging data, the shear wave elastography data, and the quasi-static elastography data, determine the operating parameters when operating on the target tissue; The operation on the target tissue includes marking the target tissue, and the operation parameters include the marking location; determining the operation parameters for operating on the target tissue based on the ultrasound imaging data, the shear wave elastography data, and the quasi-static elastography data, including: Based on at least one of the ultrasound imaging data, the shear wave elastography data, and the quasi-static elastography data, the edge contour features of the target tissue are obtained, and based on the edge contour features, a first alternative marking position is obtained when marking the target tissue; specifically, this includes: determining whether there is a protrusion on the edge contour of the target tissue based on the edge contour features; if there is a protrusion on the edge contour, taking at least part of the protrusion location as the first alternative marking position; if there is no protrusion on the edge contour, determining a first alternative marking position at a preset distance on the edge contour; Based on the ultrasound imaging data, the shear wave elastography data, and the quasi-static elastography data, the soft and hard characteristic distribution information of the target tissue is obtained, and based on the soft and hard characteristic distribution information, the locations where the softness and hardness exceed a preset threshold are used as second candidate marker locations, wherein the soft and hard characteristic distribution information represents the softness and hardness of the target tissue at different locations; Based on the first candidate marker position and the second candidate marker position, a marker position for marking the target tissue is determined; Furthermore, based on the ultrasound imaging data, the shear wave elastography data, and the quasi-static elastography data, the distribution information of the soft and hard properties of the target tissue is obtained, including: By fusing the shear wave elastography data and the quasi-static elastography data, the elastic distribution information of the target tissue is obtained; The density distribution and composition distribution information of the target tissue are obtained through the ultrasound imaging data. The soft and hard property distribution information is determined by the density distribution information, the composition distribution information, and the elasticity distribution information.

2. The method as described in claim 1, characterized in that, A pressure-sensitive device is provided between the liquid chamber and the pressure measuring device; The detection of hydraulic pressure in the liquid chamber includes: The pressure-sensitive characteristic parameter value of the pressure-sensitive device is detected, and the hydraulic pressure in the liquid chamber is determined based on the detected result.

3. The method as described in claim 1, characterized in that, The pressure-sensing device further includes a first contact layer located on one side of the liquid chamber and a second contact layer located on the other side of the liquid chamber. The first contact layer is used to contact the elastic detection probe, and the second contact layer is used to contact the skin surface of the target tissue area. Before acquiring the ultrasonic imaging data and the shear wave elastography data using the elasticity detection probe, the method further includes: The first acoustic impedance of the first contact layer and the second acoustic impedance of the second contact layer are respectively adapted to the liquid in the liquid cavity.

4. A parameter determination device for determining tissue operation parameters based on a detection device, characterized in that, The detection device includes an elastic detection probe and a pressure detection device connected to the elastic detection probe. The pressure detection device includes a pressure measuring device and a pressure sensing device. The pressure sensing device includes a liquid chamber for containing liquid. The pressure measuring device is connected to the liquid chamber. The device includes: A hydraulic detection module is used to detect the hydraulic pressure of the liquid chamber by means of the pressure measuring device when the elastic detection probe presses the skin surface of the target tissue area through the pressure sensing device. The data acquisition module is used to acquire ultrasound imaging data and shear wave elastography data of the target tissue and other tissues surrounding the target tissue using the elastic detection probe when the hydraulic pressure meets the preset pressure range. The data acquisition module is also used to acquire quasi-static elastography data of the target tissue and other surrounding tissues through the elastic detection probe when the elastic detection probe presses the skin surface of the target tissue area through the pressure sensing device. The quasi-static elastography data is obtained by emitting a third ultrasonic signal to the target tissue and other surrounding tissues and receiving the corresponding echo signal when the pressure on the skin surface has not yet met the preset pressure range, and when the pressure is adjusted by the lifting or pressing action of the elastic detection probe. The operation on the target tissue includes marking the target tissue, and the operation parameters include the marking position; The determining module is also used to determine the operating parameters when operating on the target tissue based on the ultrasound imaging data, the shear wave elastography data, and the quasi-static elastography data; The determining module is further configured to obtain the edge contour features of the target tissue based on at least one of the ultrasound imaging data, the shear wave elastography data, and the quasi-static elastography data, and to obtain a first candidate marking position for marking the target tissue based on the edge contour features; specifically, it includes: determining whether there is a protrusion on the edge contour of the target tissue based on the edge contour features; if there is a protrusion on the edge contour, taking at least part of the protrusion location as the first candidate marking position; if there is no protrusion on the edge contour, determining a first candidate marking position at a preset distance on the edge contour; Based on the ultrasound imaging data, the shear wave elastography data, and the quasi-static elastography data, the soft-hardness distribution information of the target tissue is obtained. Based on this soft-hardness distribution information, locations where the softness or hardness exceeds a preset threshold are designated as second candidate marker locations. The soft-hardness distribution information represents the softness or hardness of the target tissue at different locations. Based on the first and second candidate marker locations, a marker location for marking the target tissue is determined. Furthermore, when obtaining the soft-hardness distribution information of the target tissue based on the ultrasound imaging data, the shear wave elastography data, and the quasi-static elastography data, the shear wave elastography data and the quasi-static elastography data are fused to obtain the elasticity distribution information of the target tissue. The density distribution information and composition distribution information of the target tissue are obtained through the ultrasound imaging data. The soft-hardness distribution information is determined through the density distribution information, the composition distribution information, and the elasticity distribution information.

5. A computer-readable storage medium, characterized in that, The computer-readable storage medium is used to store a computer program that, when executed by a processor, implements the method as described in any one of claims 1 to 3.

6. An electronic device, characterized in that, The electronic device includes a processor and a memory, the memory being used to store a computer program that, when executed by the processor, implements the method as described in any one of claims 1 to 3.

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