A composition for improving skin color and a method for preparing the same and use thereof

Abstract

This invention belongs to the field of daily chemical products technology, and relates to a composition for improving skin tone, its preparation method, and its application. By weight, the composition comprises: barley (HORDEUM VULGARE) extract, carnosine, apple (MALUS DOMESTICA) fruit cell culture extract, and niacinamide. The skin-improving composition provided by this invention organically combines multiple components to work synergistically, not only brightening and whitening the skin, but also improving skin yellowing and redness, thus improving skin tone. It also has oil-controlling, acne-reducing, and fine-line-reducing effects, meeting diverse consumer needs. It is safe and non-irritating, and can be widely used in the cosmetics industry.

Description

Technical Field

[0001] This invention belongs to the field of daily chemical products technology, and in particular relates to a composition for improving skin tone, its preparation method and application. Background Technology

[0002] The skin is the largest immune organ in the human body, constantly facing challenges from both internal and external environments. It uses pigment regulation mechanisms to reduce skin damage caused by external stimuli. At the same time, the skin also plays a role in aesthetics and reflects an individual's health status.

[0003] Skin color varies from person to person, age, region, season, and location, and also changes with health status and emotions. The visible skin color is the color of the skin's surface; it is a combined reflection of brown melanin, red oxidized hemoglobin, blue deoxidized hemoglobin, and yellow carotene. This includes both genetically determined healthy skin color unaffected by sunlight exposure and other factors—the inherent skin color—and variable skin color, which is influenced by regulatory factors such as sunlight exposure and endocrine stimulation.

[0004] As we age and are affected by environmental factors, our skin may darken, yellow, or redden. Darkening is mainly due to melanin and pigmentation caused by factors such as ultraviolet radiation; yellowing is caused by skin glycation leading to a yellowish and dull complexion, as well as photoaging and yellowing due to skin oxidation caused by various pollutants; redness is caused by impaired barrier function and fragile, sensitive skin.

[0005] There is currently a lot of research on improving skin tone, but existing technologies for improving skin tone have the following shortcomings:

[0006] 1. The focus is mainly on "skin whitening," with extensive research on melanin targets, such as inhibiting tyrosinase activity, inhibiting melanin transfer, and promoting melanin metabolism. However, the apparent skin color is a comprehensive reflection of L*, a*, and b* values, namely, whiteness, redness, and yellowness. Therefore, comprehensively improving skin whiteness, yellowness, and redness can achieve significantly better results.

[0007] 2. According to research, most consumers with skin tone concerns are mature skin, accompanied by skin problems such as wrinkles, oiliness, and acne scars. However, the formulas of existing technologies are not comprehensive enough to meet consumers' needs for multiple synergistic effects.

[0008] 3. Traditional whitening ingredients have problems such as strong irritation requiring tolerance to be built, needing to be avoided in sunlight and not being usable during the day, and the risk of ingredients being harmful to the human body, which cannot meet consumers' needs for product safety.

[0009] Therefore, there is an urgent need to develop a product that comprehensively improves skin tone, is effective, safe, and meets consumer expectations for skin tone improvement. Summary of the Invention

[0010] In order to overcome the problems existing in the prior art, the present invention provides a composition for improving skin color, a method for preparing the composition, and its application.

[0011] The compositions provided by this invention are complementary in their mechanisms of action. When used together, they can improve skin brightness, yellowness, and redness, as well as wrinkles, acne scars, and excessive oil production, thereby improving skin tone and texture.

[0012] Meanwhile, the composition preparation process provided by this invention is simple and highly operable. The stability of the active ingredients can be maintained during the preparation process. The composition that improves skin tone can be used in the preparation of cosmetics or skin care products. When using cosmetics or skin care products, there is no need to avoid light. The skin feels refreshing and is easily absorbed, and it will not irritate the skin.

[0013] The objective of this invention can be achieved through the following technical solutions:

[0014] The present invention first provides a composition for improving skin tone, the composition comprising barley extract, niacinamide, carnosine and apple fruit cell culture extract.

[0015] In one embodiment of the present invention, the skin-improving composition comprises the following components in parts by weight: 0.5-40 parts of barley extract, 0.5-40 parts of niacinamide, 0.01-10 parts of carnosine, and 0.5-40 parts of apple fruit cell culture extract.

[0016] In a preferred embodiment of the present invention, the skin-improving composition comprises the following components in parts by weight: 30-40 parts barley extract, 30 parts niacinamide, 5-10 parts carnosine, and 25-30 parts apple fruit cell culture extract.

[0017] In embodiments of the present invention, in addition to barley extract, niacinamide, carnosine, and apple fruit cell culture extract, the composition for improving skin tone may also include an instant whitening and brightening component, which is selected from one or more of pearl powder, titanium dioxide, zinc oxide, bismuth oxychloride, or barium sulfate.

[0018] In embodiments of the present invention, in addition to barley extract, niacinamide, carnosine, and apple fruit cell culture extract, the composition for improving skin tone may also include solvents and excipients permitted for use in cosmetics or skin care products. The solvent may be, for example, water, alcohols, etc., and the excipients may be, for example, one or more of surfactants, thickeners, conditioning agents, moisturizers, preservatives, chelating agents, and sunscreens.

[0019] In this invention, the barley extract contains maltine, a certain amount of maltguanidine, catechins, ergosterol, amino acids, amylase, etc. The content of maltine in the barley extract is related to the specific method of obtaining the barley extract.

[0020] The barley extract is preferably barley malt extract, and even more preferably barley malt extract taken on the fourth day of germination, so as to obtain a barley extract with a barley malt alkaloid content of more than 4000 ppm.

[0021] In one embodiment of the present invention, the barley extract preparation method is as follows: take fresh, mature, and plump clean barley, soak it in water for 6-12 hours, build a bed on a flat rack, place the barley on the bed, cover it with a layer of straw, and maintain a suitable temperature (preferably 20-25℃), humidity (preferably 42-48%), ventilation conditions (preferably timely ventilation and oxygen supply in the early stage of germination, which is conducive to enzyme formation; ventilation should be appropriately reduced in the later stage of germination), and a suitable malt layer thickness. Preferably, on the fourth day of barley germination, extract the barley malt and barley together to obtain a barley extract with a malt alkaloid content of more than 4000ppm.

[0022] Furthermore, the extraction method specifically includes mechanical pulverization, enzymatic extraction, centrifugation to obtain the supernatant, and vacuum concentration to obtain a barley extract with a malt alkaloid content of 4000 ppm or higher.

[0023] In this invention, the nicotinamide can be obtained by chemical synthesis or purchased.

[0024] In one embodiment of the present invention, the nicotinamide is prepared by alkali-catalyzed hydrolysis of 3-cyanopyridine. After purification processes including ion exchange and evaporation to remove water, the separated nicotinamide is spray-dried to produce the final product with a purity of over 99%, and then packaged into containers.

[0025] Nicotinamide typically contains nicotinic acid, and a certain amount of nicotinic acid may cause skin redness. In the preparation process of nicotinamide in this invention, the minimum amount of nicotinic acid is ensured, and the concentration of nicotinic acid is controlled within 100 ppm.

[0026] In this invention, the carnosine can be obtained in-house through chemical synthesis or purchased.

[0027] In one embodiment of the present invention, the carnosine is prepared by chemical synthesis, and is in the form of a white, odorless, transparent powder with a purity >99% and is soluble in water.

[0028] In this invention, the apple fruit cell culture extract can be prepared in-house or purchased.

[0029] In one embodiment of the present invention, the method for preparing the apple fruit cell culture extract is as follows: live apple (MALUS DOMESTICA) plant cells are selected for extraction; cell differentiation is promoted using auxins, etc.; callus cells are cultured; after suspension proliferation, bioscaled, and purified to obtain a cell suspension; the suspension is then filtered and sterilized to obtain the apple fruit cell culture extract. The use of cell culture technology maximizes the preservation of plant cell viability, and the cell membrane forms natural lipid encapsulations, which facilitates the transdermal absorption of the active ingredients. The present invention further provides a method for preparing the skin-improving composition, wherein a certain amount of barley extract, niacinamide, carnosine, and apple fruit cell culture extract are thoroughly mixed and stirred evenly to obtain the skin-improving composition.

[0030] In one embodiment of the present invention, during the preparation of the skin-improving composition, the mixing temperature is 10-30°C, and the stirring speed is 100-200 r / min.

[0031] The present invention further provides the application of the skin tone improving composition, wherein the skin tone improving composition is used in the preparation of cosmetics or skin care products, wherein, based on the total weight of the cosmetics or skin care products, the cosmetics or skin care products contain 0.01-50% of the skin tone improving composition; and 50-99.99% of cosmetic or skin care product solvents and excipients; preferably, the cosmetics or skin care products contain 0.01-30% of the skin tone improving composition; and 70-99.99% of cosmetic or skin care product solvents and excipients.

[0032] In one embodiment of the present invention, the excipients include one or more of surfactants, thickeners, conditioning agents, humectants, preservatives, chelating agents, colorants, and sunscreens. The solvents include deionized water, alcohols, etc.

[0033] In one embodiment of the present invention, the cosmetics or skin care products are made into various cosmetics or skin care products such as skin-improving facial cleanser, skin-improving face cream, skin-improving lotion, skin-improving toner, skin-improving face mask, skin-improving BB cream, skin-improving foundation, skin-improving eye cream, skin-improving body cream, or skin-improving gel.

[0034] The present invention further provides a cosmetic or skin care product for improving skin tone, comprising, by total weight, 0.01-50% of a skin tone improving composition and 50-99.99% of a cosmetic or skin care solvent and excipients. Preferably, the cosmetic or skin care product comprises 1-30% of a skin tone improving composition and 70-99% of a cosmetic or skin care solvent and excipients.

[0035] In one embodiment of the present invention, the skin-improving skincare product is a lotion. By weight percentage, the raw material components of the skin-improving lotion include: 0.01-50% of a skin-improving composition, 0.2% xanthan gum, 3% 1,3-butanediol, 2% glycerin, 0.2% trehalose, 0.05% EDTA-2Na, 0.4% p-hydroxyacetophenone, 0.4% 1,2-hexanediol, and the balance being deionized water. Preferably, the raw material components of the skin-improving lotion include: 0.01-30% of a skin-improving composition, 0.2% xanthan gum, 3% 1,3-butanediol, 2% glycerin, 0.2% trehalose, 0.05% EDTA-2Na, 0.4% p-hydroxyacetophenone, 0.4% 1,2-hexanediol, and the balance being deionized water. More preferably, the skin-improving lotion may contain 0.01%, 1%, 5%, 10%, 15%, 20%, 25%, 30% of the skin-improving composition, etc.

[0036] Furthermore, the preparation method of the skin-improving lotion includes the following steps:

[0037] (1) Pre-disperse 1,3-butanediol and xanthan gum evenly, add them to deionized water and stir until dissolved;

[0038] (2) Add trehalose and EDTA-2Na to the product prepared in (1) and stir to disperse it evenly. Heat to 80-85℃, add p-hydroxyacetophenone and stir evenly. Stop heating after it is completely dissolved.

[0039] (3) Cool the product prepared in (2) to 38-42°C, add the skin-improving composition, add glycerin and 1,2-hexanediol after stirring evenly, and discharge the product after stirring evenly.

[0040] Furthermore, the skin-improving lotion is prepared by the following method:

[0041] Pre-disperse 1,3-butanediol and xanthan gum evenly, then add them to deionized water and stir until completely dissolved. Add trehalose and EDTA-2Na, and stir at 200-400 r / min to disperse evenly. Then heat to 80-90℃, add p-hydroxyacetophenone and stir evenly until completely dissolved, then stop heating. Cool to 38-42℃, add the skin-improving composition, and stir evenly. Add glycerin and 1,2-hexanediol evenly and add to the system. Stir evenly and then dispense to obtain the skin-improving emulsion.

[0042] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0043] 1) The skin tone improvement composition provided by the present invention contains barley extract, niacinamide, carnosine, and apple fruit cell culture extract. The combined application of these components can improve skin brightness, yellowness, redness, wrinkles, acne marks and oiliness, thereby achieving the effect of improving skin tone and skin texture.

[0044] 2) The skin-improving composition provided by the present invention has a simple preparation process and is highly operable. The stability of the active ingredients can be maintained during the preparation process, and the skin-improving composition can be used in the preparation of cosmetics or skin care products.

[0045] 3) The active ingredients in the skin-improving composition provided by this invention exhibit strong photostability. Specifically, niacinamide itself has a stable molecule that is not easily photodegraded; carnosine has strong antioxidant properties and provides full-spectrum protection; and apple fruit cell culture extract can improve photostability to a certain extent. Therefore, the composition of this invention has relatively strong photostability, and when used in cosmetics or skincare products, strict light avoidance is not required.

[0046] 4) When the skin tone improvement composition provided by the present invention is used in cosmetics or skin care products, the cosmetics or skin care products feel refreshing and are easily absorbed when used, without causing skin irritation, and can improve skin tone and skin texture. Therefore, it has important practical significance and broad market prospects. Attached Figure Description

[0047] Figure 1 This is a facial skin tone improvement image (collected by a C-CUBE device) of the skin tone improvement composition provided by the present invention.

[0048] Figure 2 This is a facial skin texture improvement image (captured by a Visia device) of the skin tone improvement composition provided by the present invention.

[0049] Figure 3 The image shows the improvement in facial pigmentation and acne caused by the skin tone composition provided by this invention (collected by a Visia device). Detailed Implementation

[0050] To make the objectives, technical solutions, and advantages of this invention clearer, the technical solutions of this invention will be described in detail below. Obviously, the described embodiments are merely some embodiments of this invention, and not all embodiments. Based on the embodiments of this invention, all other implementation methods obtained by those skilled in the art without creative effort are within the scope of protection of this invention.

[0051] This invention discloses a composition for improving skin tone, comprising barley extract, niacinamide, carnosine, and apple fruit cell culture extract.

[0052] The following are descriptions of the technical efficacy of the raw material components.

[0053] Barley (HORDEUM VULGARE) extract:

[0054] Fresh, mature, and clean barley is soaked in water for 6-12 hours, then placed on a flat rack, covered with a layer of straw, and kept at a temperature of 20-25℃, humidity of 42-48%, and with adequate ventilation (timely ventilation and oxygen supply in the early stage of germination is conducive to enzyme formation; ventilation should be appropriately reduced in the later stage of germination). On the fourth day of barley germination, the barley malt and barley are extracted together to obtain an extract with a malt alkaloid content of 4000ppm.

[0055] Efficacy: Rich in 4000ppm maltine, a resorcinol-like compound whose main mechanism of action is signaling pathway inhibition, such as cyclic adenosine monophosphate (cAMP) messenger, phosphorylated CREB (pCREB), microphthalmia-associated transcription factor MITF, tyrosinase, DHICA oxidase TRP-1, and dopachrome isomerase TRP-2. It possesses a strong whitening effect by reducing melanin content, earning it the nickname "Plant 377" or "Plant Resorcinol." Precisely targeting malt on the 4th day of germination yields abundant maltine. Compared to traditional resorcinol-based whitening agents, maltine exhibits excellent photothermal stability, does not discolor, has good solubility, and is easy to apply.

[0056] Niacinamide

[0057] Efficacy: Numerous clinical trials have confirmed the wide range of benefits of niacinamide. Niacinamide prevents pigmentation from appearing on the skin surface, particularly inhibiting melanosome migration by up to 68%. Simultaneously, it significantly enhances the skin's ability to repair cyclobutane pyrimidine dimer (CPD) photodamage caused by ultraviolet and blue light, promotes collagen synthesis, and improves fine lines. Furthermore, niacinamide can reduce acne, including decreasing its severity, and effectively reduce sebum formation and secretion.

[0058] Carnosine

[0059] Efficacy: Carnosine is a dipeptide composed of β-alanine and L-histidine, naturally occurring in various tissues of the body, especially abundant in muscle and brain tissue. Carnosine has a wide range of functions, including antioxidant and anti-glycation properties, as well as full-spectrum protection, resulting in radiant and even-toned skin.

[0060] Apple fruit cell culture extract

[0061] Benefits: Soothes skin, helps reduce irritation and redness, helps even out skin tone, and leaves skin radiant. It also enhances skin's resilience, effectively protecting it from external irritants and damage.

[0062] In this invention, the composition for improving skin tone works synergistically through the different mechanisms of action of its components. Specifically, barley extract primarily targets the skin's primary concern—darkness—by reducing melanin production; niacinamide targets skin metabolism, promoting melanin migration and metabolism, controlling oil production, enhancing the repair ability of photodamage, promoting collagen synthesis, improving fine lines, and addressing skin tone issues; carnosine targets the skin's primary concern—yellowness—by providing antioxidant and anti-glycation benefits, alleviating yellowing and dullness caused by glycation and photoaging; and apple fruit cell culture extract targets the skin's primary concern—redness—by soothing the skin, reducing redness, and enhancing the skin barrier function. These four active ingredients complement each other in their mechanisms of action, targeting the three major skin tone concerns of Chinese women—darkness, yellowness, and redness. Their combined application reduces melanin production, combats glycation, soothes redness, promotes metabolism, and promotes collagen synthesis, thereby achieving the effects of lightening dark skin, removing yellowing and redness, evening skin tone, delaying aging, and combating the signs of aging and environmental damage. In addition, water and alcohols can be added as moisturizers to finally prepare a skin tone improving composition that can not only brighten the skin and make it whiter, but also improve the yellowness and redness of the skin and improve skin tone. At the same time, it has the effects of oil control, soothing and reducing fine lines, meeting the diverse needs of consumers. It is safe and non-irritating and can be widely used in the cosmetics industry.

[0063] In the following embodiments, the unit of weight parts can be g or kg.

[0064] Unless otherwise specified, all raw materials used in the following examples are commercially available products. Barley extract was purchased from CLARIANT.

[0065] Niacinamide purchased from DSM

[0066] Carnosine was purchased from Symrise Germany.

[0067] Apple fruit cell culture extract was purchased from Naolys, France.

[0068] Example 1

[0069] This embodiment provides a skin tone improving lotion, the raw material components of which include (by weight percentage):

[0070] Skin tone improving composition 2%, xanthan gum 0.2%, 1,3-butanediol 3%, glycerin 2%, trehalose 0.2%, EDTA-2Na 0.05%, p-hydroxyacetophenone 0.4%, 1,2-hexanediol 0.4%, deionized water balance.

[0071] The raw material components of the composition, based on the total weight of the skin-improving composition, include:

[0072] 30 parts barley extract, 30 parts nicotinamide, 10 parts carnosine, and 30 parts apple fruit cell culture extract.

[0073] The skin-improving lotion was prepared using the following method:

[0074] Pre-disperse 1,3-butanediol and xanthan gum evenly, then add them to deionized water and stir until completely dissolved; add trehalose and EDTA-2Na and stir at 300 r / min to disperse evenly, then heat to 85℃ and add p-hydroxyacetophenone and stir evenly until completely dissolved, then stop heating; cool to 40℃ and add the skin-improving composition, stir evenly, then add glycerin and 1,2-hexanediol evenly and add to the system, stir evenly, then discharge and package to obtain the skin-improving emulsion.

[0075] Example 2

[0076] This embodiment provides a skin tone improving lotion, the raw material components of which include (by weight percentage):

[0077] Skin tone improving composition 5%, xanthan gum 0.2%, 1,3-butanediol 3%, glycerin 2%, trehalose 0.2%, EDTA-2Na 0.05%, p-hydroxyacetophenone 0.4%, 1,2-hexanediol 0.4%, deionized water balance.

[0078] The raw material components of the composition, based on the total weight of the skin-improving composition, include:

[0079] 40 parts barley extract, 30 parts nicotinamide, 5 parts carnosine, and 25 parts apple fruit cell culture extract.

[0080] The skin-improving lotion was prepared using the following method:

[0081] Pre-disperse 1,3-butanediol and xanthan gum evenly, then add them to deionized water and stir until completely dissolved; add trehalose and EDTA-2Na and stir at 300 r / min to disperse evenly, then heat to 85℃ and add p-hydroxyacetophenone and stir evenly until completely dissolved, then stop heating; cool to 40℃ and add the skin-improving composition, stir evenly, then add glycerin and 1,2-hexanediol evenly and add to the system, stir evenly, then discharge and package to obtain the skin-improving emulsion.

[0082] The only difference between Comparative Examples 1-8 is the composition of the skin-improving composition in the skin-improving lotion raw materials. The amounts of other raw materials and the preparation methods are the same as in Example 1.

[0083] Table 1. Composition of the skin-improving compositions in Examples 1-2, Comparative Examples 1-8, and Blank Examples

[0084]

[0085] Blank example

[0086] This blank example provides a basic emulsion whose raw material components include:

[0087] Free of skin tone-improving compositions, xanthan gum 0.2%, 1,3-butanediol 3%, glycerin 2%, trehalose 0.2%, EDTA-2Na 0.05%, p-hydroxyacetophenone 0.4%, 1,2-hexanediol 0.4%, deionized water balance.

[0088] The base emulsion was prepared using the following method:

[0089] Pre-disperse 1,3-butanediol and xanthan gum evenly, then add them to deionized water and stir until completely dissolved; add trehalose and EDTA-2Na and stir at 300 r / min to disperse evenly, then heat to 85℃ and add p-hydroxyacetophenone and stir evenly until completely dissolved, then stop heating; stir glycerin and 1,2-hexanediol evenly, add them to the system, stir evenly, and then discharge and package to obtain the skin-improving emulsion.

[0090] Effect verification test case

[0091] Human testing

[0092] 1) Testing Method

[0093] Test participants: 231 healthy women (aged 23–55, mean age 37.1 years) were randomly divided into 11 groups of 21 participants each (one participant in each of the comparative and control groups withdrew from the test due to non-compliance, leaving 20 participants in each group; the remaining groups had 21 participants each). Gender was not limited, but participants with darker skin tones were preferred. Each group used the same product formula. The values ​​in Tables 3–6 represent the average values ​​for each group of 21 or 20 participants.

[0094] Test areas: Visia full face test; C-CUBE test area is the intersection of the outer corner of the eye and the area below the wing of the nose (left side); patch safety test area is the flexor side of the forearm.

[0095] How to use: Apply to the entire face, once in the morning and once in the evening after washing your face. Continue to use for 4 weeks, avoiding exposure to outdoor sun.

[0096] Test conditions: Subjects rested quietly for 30 minutes in an environment with a temperature of 21±1℃ and a relative humidity of 50±5%RH before being tested.

[0097] Testing instruments: Visia7 facial imaging system (Canfield, USA), C-Cube (PIXIENCE).

[0098] Performance indicators:

[0099] Visia7 is used for facial image acquisition and analysis of multiple skin indicators (spots, wrinkles, red areas, and purplish-redness).

[0100] Cube is a lightweight, portable integrated system that performs 3D measurements using photometric stereometry. By acquiring 2D and 3D images of the skin, it analyzes indicators such as L*, a*, b*, erythema, ITA, and melanin to characterize improvements in skin smoothness, luster, and brightness.

[0101] 8. Testing period: Before use (D0), after 28 days of use (D28)

[0102] 9. Data processing: All results are the average of the results of 20 or 21 subjects who actually participated in the test.

[0103] 2) Test Results

[0104] 2.1 Security Testing

[0105] Place the emulsion from the test subject into the small chamber of the spot tester, with a volume of approximately 0.020 mL to 0.025 mL. Do not place any substance in the control well.

[0106] The test patch containing the test substance was applied to the flexor side of the subject's forearm using hypoallergenic adhesive tape (manufacturer: Shanghai Medical Instruments (Group) Co., Ltd. Sanitary Materials Factory). The tape was gently pressed with the palm of the hand to ensure even application to the skin for 24 hours. After removing the test patch, the skin reaction was observed at 30 minutes, 24 hours, and 48 hours according to the standards shown in Table 1, and the observation results were recorded. The grading standards are shown in Table 2, and the test results are shown in Table 3.

[0107] Table 2. Grading Criteria for Skin Reaction in Skin Occlusive Patch Tests

[0108]

[0109] Table 3. Results of human skin patch tests for Examples 1-2, Comparative Examples 1-8, and Blank Examples of the present invention.

[0110]

[0111] As can be seen from the examples and comparative examples in Table 3, when the skin-improving composition provided by the present invention contains four of the following: barley extract, niacinamide, carnosine, and apple fruit cell culture extract, the combined application of these components does not irritate the skin.

[0112] 2.2 Skin tone improvement results

[0113] Skin color testing was performed on the emulsions obtained from the examples, comparative examples, and blank examples using a C-Cube (PIXIENCE) device. The test area was the intersection of the outer corner of the eye and the area below the nasal wing (randomly selected side).

[0114] ITA, or Individual Typology Angle, is an indicator used to characterize the overall visual effect of skin color.

[0115] Table 4 shows the skin tone improvement results of test subjects in Examples 1-2, Comparative Examples 1-8, and Blank Examples after 28 days of use.

[0116] On one subject, the improvement in facial skin tone before and after using the lotion obtained in Example 1 was as follows: Figure 1 The above, Figure 1 The left and right images represent magnified improvements in facial skin tone before and after 28 days of use, respectively. As you can see, after 28 days of use, skin brightness increased, redness decreased, yellowness decreased, and overall skin texture improved significantly.

[0117] L was measured by C-Cube before and 28 days after the subjects used the products in the examples and comparative examples. * a * , b * The values ​​of heme, melanin, and ITA° were measured, and the improvement rate was calculated, as shown in Table 4.

[0118] Taking Example 1 as an example, the L of the first 21 subjects was tested. * a * , b * The average values ​​for heme, melanin, and ITA° were 57.019, 10.522, 15.233, 29.285, 53.648, and 24.652, respectively.

[0119] After 28 days of use of the emulsion in Example 1, the average values ​​of L*, a*, b*, heme, melanin, and ITA° in the subjects were 58.473, 9.226, 14.269, 25.680, 50.955, and 39.529, respectively.

[0120] The improvement rates for L*, a*, b*, heme, melanin, and ITA° were +2.55%, -12.31%, -6.33%, -12.31%, -5.02%, and +60.35%, respectively.

[0121] Table 4. Skin tone improvement effect after 28 days of use.

[0122]

[0123] Referring to Table 4, the human body test results show that after 28 days of use of the lotions from Examples 1-2 and Comparative Examples 1-8 of this invention, the subjects' skin brightness (L*) increased, redness (a*) decreased, yellowness (b*) decreased, hemoglobin decreased, melanin decreased, and luminance (ITA°) increased. This indicates that the cosmetics from Examples 1-2 and Comparative Examples 1-8 of this invention all have the effect of brightening skin tone. However, the skin tone improvement effect of Examples 1-2 (i.e., simultaneously containing barley extract, niacinamide, carnosine, and apple fruit cell culture extract) is better than that of Comparative Examples 7 and 8 containing three of these ingredients, and better than that of Comparative Examples 4, 5, and 6 containing two of these ingredients. The skin tone improvement effect of Comparative Examples 1, 2, and 3 containing only one of these ingredients is poor. It can be seen that the skin tone improvement composition provided by this invention simultaneously contains barley extract, niacinamide, carnosine, and apple fruit cell culture extract, and the combined application of these components has a synergistic effect. It can also be seen that improving L*, a*, and b* individually in Comparative Examples 1-3 does not significantly improve the overall skin tone ITA°, while improving L*, a*, and b* values ​​simultaneously in Examples 1 and 2 can significantly improve the overall skin tone ITA° by more than 60.35%, indicating that improving skin whiteness, yellowness, and redness can achieve good results to a large extent.

[0124] 2.3 Results of improvement in spots, wrinkles, redness, and oiliness

[0125] The emulsions obtained in Examples 1-2, Comparative Examples 1-8, and the blank sample were tested for indicators such as spots, wrinkles, redness, and oiliness using the Visia7 facial imaging system (Canfield, USA). The Visia7 test area was the entire face. Table 5 shows the improvement results of spots, wrinkles, redness, and oiliness parameters after 28 days of use by the test subjects in Examples 1-2, Comparative Examples 1-8, and the blank sample.

[0126] In two subjects, the improvement in facial skin texture before and after using the lotion obtained in Example 1 was as follows: Figure 2 and 3 The above, Figure 2 The left and right images refer to the improvement in skin tone on the right cheek before and after 28 days of use, respectively. Figure 2 After 28 days of use, skin redness showed significant improvement, skin tone was noticeably brighter, and acne scars and pits improved, resulting in smoother and more even skin texture. From Figure 3 After 28 days of use, skin pigmentation decreased, and forehead acne improved significantly, leaving almost no acne scars.

[0127] The scores for spots, wrinkles, redness, and oiliness of the subjects were measured by instruments before and after 28 days of using the products in the examples and comparative examples, and the improvement rate was calculated, as shown in Table 5.

[0128] Taking Example 1 as an example, the average scores of spot, wrinkle, redness and oiliness of the first 21 subjects were 26.779, 25.233, 11.785 and 10.648, respectively.

[0129] After 28 days of use of the lotion in Example 1, the average scores for spots, wrinkles, redness, and oiliness were 25.883, 22.644, 10.326, and 9.945, respectively.

[0130] The improvement rates for spot score, wrinkle score, redness score, and oil score were -3.35%, -10.26%, -12.38%, and -6.60%, respectively.

[0131] Table 5. Skin pore and texture effects after 28 days of use.

[0132]

[0133] As shown in Table 5, after 28 days of using the lotions from Examples 1-2 and Comparative Examples 1-8, spots, wrinkles, red areas, and purplish-redness (oil) were all improved. This indicates that the composition of the present invention, in addition to improving skin tone, also improves spots, wrinkles, red areas, and purplish-redness (oil) in cosmetic applications, and also improves acne scars and marks. Furthermore, comparing Examples 1-2, Comparative Examples 1-8, and the blank example, it can be seen that Examples 1-2 of the present invention (i.e., containing barley extract, niacinamide, carnosine, and apple fruit cell culture extract) are more effective in improving spots, wrinkles, red areas, and purplish-redness (oil) than the examples containing only 1-3 of the four ingredients. It can be seen that the skin-improving composition provided by the present invention simultaneously contains barley extract, niacinamide, carnosine, and apple fruit cell culture extract, and the combined application of these components has a synergistic effect.

[0134] Based on the safety and efficacy tests conducted, the skin tone improvement composition provided by this invention is specifically designed for dull skin. It improves skin brightness, yellowness, and redness, fades blemishes, reduces wrinkles, and reduces oiliness, thus improving skin tone and texture. Furthermore, the combination of these ingredients is safe and non-irritating.

[0135] The above description of the embodiments is provided to enable those skilled in the art to understand and use the invention. It will be apparent to those skilled in the art that various modifications can be made to these embodiments, and the general principles described herein can be applied to other embodiments without inventive effort. Therefore, the present invention is not limited to the above embodiments, and any improvements and modifications made by those skilled in the art based on the disclosure of the present invention without departing from the scope of the invention should be within the protection scope of the present invention.

Claims

1. A composition for improving skin color, characterized by comprising: It consists of the following components in parts by weight: 30-40 parts barley extract, 30 parts nicotinamide, 5-10 parts carnosine, and 25-30 parts apple fruit cell culture extract.

2. The composition for improving skin tone according to claim 1, characterized in that, The barley extract refers to an extract with a malt alkaloid content of more than 4000 ppm obtained by extracting barley malt and barley together after barley germination. The nicotinamide has a purity of over 99% and contains less than 100 ppm of nicotinic acid; The carnosine has a purity of over 99%.

3. The method of preparing the skin color-improving composition according to claim 1, characterized by, A certain amount of barley extract, niacinamide, carnosine, and apple fruit cell culture extract are thoroughly mixed in proportion and stirred evenly to obtain the skin-improving composition. The mixing temperature is 10-30℃, and the stirring speed is 100-200 r / min.

4. Use of the skin color improving composition according to claim 1, characterized in that, When the skin-improving composition is used in the preparation of a cosmetic, the cosmetic contains 0.01-50% of the skin-improving composition and 50-99.99% of cosmetic solvents and excipients, based on the total weight of the cosmetic.

5. Use according to claim 4, characterized in that, The excipients include one or more of surfactants, thickeners, conditioning agents, humectants, preservatives, chelating agents, colorants, and sunscreens. The solvent includes one or more of deionized water and alcohols.

6. Use according to claim 4, characterized in that, The cosmetics are formulated as skin-enhancing facial cleansers, skin-enhancing face creams, skin-enhancing lotions, skin-enhancing toners, skin-enhancing face masks, skin-enhancing BB creams, skin-enhancing foundations, skin-enhancing eye creams, skin-enhancing body creams, or skin-enhancing gels.

7. Use according to claim 6, characterized in that, By weight percentage, the raw material components of the skin-improving lotion include: a skin-improving composition, xanthan gum, 1,3-butanediol, glycerin, trehalose, EDTA-2Na, p-hydroxyacetophenone, 1,2-hexanediol, and deionized water as the balance.

8. Use according to claim 7, characterized in that, The preparation method of the skin-improving lotion includes the following steps: (1) Pre-disperse 1,3-butanediol and xanthan gum evenly, add them to deionized water and stir until dissolved; (2) Add trehalose and EDTA-2Na to the product prepared in (1) and stir to disperse it evenly. Heat it, add p-hydroxyacetophenone and stir evenly. Stop heating after it is completely dissolved. (3) Cool the product prepared in (2), add the skin-improving composition, glycerin, and 1,2-hexanediol, stir evenly and then discharge.

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