Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for processing sequence data
By employing multiple adapter trimming and splicing methods, combined with unique molecular identifiers and barcode matching, the sequencing data processing workflow was optimized, solving the problem of time-consuming and labor-intensive genetic data processing and achieving rapid and accurate genetic sequence determination.
CN116888673BActive Publication Date: 2026-06-16BRUKER SPACE BIOLOGY
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- BRUKER SPACE BIOLOGY
- Filing Date
- 2021-10-08
- Publication Date
- 2026-06-16
AI Technical Summary
⚠Technical Problem
Existing technologies are time-consuming and labor-intensive when processing genetic data, making it difficult to quickly and effectively determine the genetic sequence in sequencing reads.
⚗Method used
A multi-step adapter trimming and splicing method was adopted, combined with unique molecular identifier (UMI) and barcode matching, to optimize the sequencing data processing workflow, including adapter trimming, splicing, extraction, first matching and second matching, and read processing was performed using known insert length and quality score.
🎯Benefits of technology
It significantly improves the speed and specificity of genetic data processing, and ensures the accuracy and efficiency of reads by multiple adapter trimming and splicing, while reducing processing time.
✦ Generated by Eureka AI based on patent content.
Smart Images
Figure CN116888673B_ABST
Abstract
Embodiments of the present disclosure relate to systems, devices, apparatuses, and methods for processing sequencing data in order to determine the identity of DNA fragments from a plurality of reads contained in a sequencing data file.
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