Filling apparatus for cryogenic vials

Abstract

This invention relates to the field of storage device technology, specifically providing a filling device for cryopreservation tubes, aiming to solve the technical problem of low filling efficiency when filling cryopreservation tubes into cryopreservation tube sleeves in the prior art. To this end, the filling device of this invention includes a fixed member, a rotating member, and a first tube-pushing member. The fixed member has a receiving cavity and a first and second dispensing port communicating with the receiving cavity. The rotating member is pivotally connected to the fixed member and can rotate within the receiving cavity. The rotating member has a first and a second receiving groove that are spaced apart along the axial direction and communicate with each other. The first and second receiving grooves can reach a first and a second station spaced apart along the rotation direction of the rotating member as the rotating member rotates. At the first station, the two receiving grooves are respectively connected to the two dispensing ports; at the second station, the second end of the first receiving groove faces the first tube-pushing member, allowing the first tube-pushing member to extend into the first receiving groove to push the tube.

Description

Technical Field

[0001] This invention relates to the field of storage device technology, and specifically provides a filling device for cryopreservation tubes. Background Technology

[0002] In recent years, due to the rapid development of the biopharmaceutical and medical fields, the demand for low-temperature storage equipment has been increasing. In order to maintain the activity of biological samples, they often need to be preserved in a low-temperature or ultra-low-temperature storage environment during production and experimentation.

[0003] In the process of storing biological samples, in order to facilitate the classification and retrieval of samples, multiple cryovials containing biological samples need to be placed into a cryovial sleeve, and then the multiple cryovial sleeves are placed into a cryovial box for storage, thus realizing the classification and orderly storage of biological samples.

[0004] However, in the existing technology, the degree of automation is low and the filling efficiency is low when filling cryopreservation tubes into cryopreservation tube sleeves.

[0005] Therefore, a new technical solution is needed in this field to solve the above problems. Summary of the Invention

[0006] The present invention aims to solve the above-mentioned technical problem, namely, how to achieve batch filling of multiple cryopreservation tubes into cryopreservation tube sleeves and improve filling efficiency.

[0007] This invention provides a filling device, comprising a fixed component, a rotating component mounted on the fixed component, and a first pusher component. The fixed component has a receiving cavity and a first dispensing port and a second dispensing port communicating with the receiving cavity. The first dispensing port and the second dispensing port are spaced apart along the axial direction of the rotating component. The rotating component is located within the receiving cavity and pivotally connected to the fixed component. The outer peripheral surface of the rotating component is in contact with the inner peripheral surface of the receiving cavity. The outer peripheral surface of the rotating component has a first receiving groove and a second receiving groove extending along the axial direction of the rotating component. The first receiving groove can simultaneously accommodate multiple cryopreservation tubes, and the second receiving groove can accommodate one cryopreservation tube sleeve. The first end of the first receiving groove is connected to the first end of the second receiving groove. The pusher is located at the first end of the rotating member and can push the cryopreservation tube in the first receiving slot into the cryopreservation tube sleeve in the second receiving slot. The first receiving slot and the second receiving slot have a first station and a second station spaced apart along the rotation direction of the rotating member. When the first receiving slot and the second receiving slot are both located at the first station, the first receiving slot and the second receiving slot are respectively connected to the first delivery port and the second delivery port, so that the cryopreservation tube in the first delivery port and the cryopreservation tube sleeve in the second delivery port are respectively moved into the first receiving slot and the second receiving slot. When the first receiving slot and the second receiving slot are both located at the second station, the pusher can load the cryopreservation tube in the first receiving slot into the cryopreservation tube sleeve in the second receiving slot.

[0008] In the preferred embodiment of the above-mentioned filling equipment, there are multiple first receiving slots and second receiving slots, which are distributed circumferentially along the rotating member. The circumferential distance between two adjacent first receiving slots and the circumferential distance between two adjacent second receiving slots are both equal to the circumferential distance between the first station and the second station.

[0009] In the preferred embodiment of the above-mentioned filling equipment, the number of the first receiving slot and the second receiving slot is at least three. The first receiving slot and the second receiving slot also have a third station. The first station, the second station and the third station are distributed sequentially at intervals along the rotation direction of the rotating member, and the circumferential distance between the third station and the second station is equal to the circumferential distance between the first station and the second station. The filling equipment also includes a second push tube member installed on the fixed member. The second push tube member is located at the first end of the rotating member and can pass through the first receiving slot and extend into the second receiving slot so that at least a portion of the cryopreservation tube sleeve in the second receiving slot extends out from the second end of the second receiving slot. When the first receiving slot and the second receiving slot are both located at the third station, the second end of the first receiving slot is directly opposite the second push tube member.

[0010] In the preferred technical solution of the above-mentioned filling equipment, the first push tube component and the second push tube component are fixedly connected or integrally formed.

[0011] In a preferred embodiment of the above-mentioned filling device, the filling device further includes a guiding mechanism, which is installed between the fixed member and the first push tube member and / or the second push tube member. The guiding mechanism can guide the first push tube member and the second push tube member during the movement of the first push tube member and the second push tube member relative to the fixed member so that the first push tube member and the second push tube member can move along the first receiving groove.

[0012] In the preferred embodiment of the above-mentioned filling equipment, the first push tube component is a first push rod, the second push tube component is a second push rod, the length of the second push rod is greater than the length of the first push rod, the filling equipment further includes a connecting frame, the first end of the first push rod and the first end of the second push rod are fixedly connected through the connecting frame, the fixing component is provided with a first through hole and a second through hole at positions corresponding to the first push rod and the second push rod, respectively, the second end of the first push rod and the second push rod are located in the first through hole and the second through hole, respectively, when the first receiving groove is located at the second station, the second end of the first receiving groove is directly opposite the first through hole, when the first receiving groove is located at the third station, the second end of the first receiving groove is directly opposite the second through hole, the guiding mechanism includes a cooperating first guiding component and a second guiding component, the first guiding component is fixedly connected to the fixing component, and the second guiding component is fixedly connected to the connecting frame.

[0013] In the preferred embodiment of the above-mentioned filling equipment, the filling equipment further includes a tube unloading component fixed on the fixed component. The tube unloading component is located at the second end of the rotating component. The tube unloading component can stop the portion of the cryopreservation tube sleeve exposed outside the second receiving groove during the rotation of the rotating component, so as to separate the cryopreservation tube sleeve from the second receiving groove. And / or, the filling equipment further includes a drive mechanism fixedly connected to the rotating component. The drive mechanism can drive the rotating component to rotate in the forward direction, and the circumferential displacement driven by the drive mechanism each time the rotating component rotates is equal to the circumferential distance between the first station and the second station, so that the first receiving groove and the second receiving groove can accurately rotate to the first station, the second station, or the third station as the rotating component rotates.

[0014] In the preferred embodiment of the above-mentioned filling equipment, the driving mechanism includes a first ratchet, a pressure rod assembly, a second ratchet, and a pawl. The first ratchet is fixedly connected to the rotating component. The pressure rod assembly is mounted on the fixed component and can move vertically up and down relative to the fixed component. The first ratchet has a plurality of first ratchet teeth spaced apart circumferentially, and the number of first ratchet teeth is equal to the number of first receiving slots. The bottom end of the pressure rod assembly can abut against the first ratchet teeth to drive the first ratchet to rotate. Each time the pressure rod assembly drives the first ratchet to rotate the rotating component forward, the circumferential displacement is equal to the circumferential distance between the first station and the second station. This allows the first receiving slot and the second receiving slot to accurately rotate to the first station, the second station, or the third station as the rotating component rotates. The second ratchet is fixedly connected to the rotating component, and the pawl is pivotally connected to the fixed component. The second ratchet has a plurality of second ratchet teeth spaced apart circumferentially, and the pawl can provide one-way stop to the second ratchet teeth to prevent the rotating component from rotating in the opposite direction.

[0015] In the preferred embodiment of the above-mentioned filling equipment, the pressure rod assembly includes a pressure rod and a spring. The spring is fixed to the fixed member in the vertical direction. The pressure rod passes through the spring. The top end of the pressure rod is fixedly connected to the top end of the spring. The bottom end of the pressure rod can abut against the first ratchet to drive the first ratchet to rotate. The spring can apply an upward thrust to the pressure rod when it is pressed down so that the pressure rod returns to its original position.

[0016] In the preferred embodiment of the above-mentioned filling device, the rotating component includes a first rotating component and a second rotating component. The filling device further includes a rotating shaft and a guide tube component mounted on the fixed component. The rotating shaft is rotatable relative to the fixed component. The first rotating component and the second rotating component are both fixedly connected to the rotating shaft and are spaced apart along the axial direction of the rotating shaft. The first rotating component is located below the first dispensing port, and the second rotating component is located below the second dispensing port. The first receiving groove is located on the outer circumferential surface of the first rotating component, and the second receiving groove is located on the outer circumferential surface of the second rotating component. The guide tube component is located between the first rotating component and the second rotating component. When the first receiving groove and the second receiving groove are located at the second working position, the two ends of the guide tube component are respectively connected to the first end of the first receiving groove and the first end of the second receiving groove. And / or, each of the first dispensing ports has an inclined first guide portion to guide the cryopreservation tube in the first dispensing port to the bottom of the first dispensing port; and / or, each of the second dispensing ports has an inclined second guide portion to guide the cryopreservation tube in the second dispensing port to the bottom of the second dispensing port.

[0017] In the case of adopting the above technical solution, the filling device of the present invention includes a fixed component, a rotating component and a first pusher component mounted on the fixed component. The fixed component has a receiving cavity and a first delivery port and a second delivery port communicating with the receiving cavity. The first delivery port and the second delivery port are spaced apart along the axial direction of the rotating component. The rotating component is located inside the receiving cavity and is pivotally connected to the fixed component. The outer peripheral surface of the rotating component is in contact with the inner peripheral surface of the receiving cavity. The outer peripheral surface of the rotating component has a first receiving groove and a second receiving groove extending along the axial direction of the rotating component. The first receiving groove can simultaneously accommodate multiple cryopreservation tubes, and the second receiving groove can accommodate one cryopreservation tube sleeve. The first end of the first receiving groove is connected to the first end of the second receiving groove. One end is connected, and the first pusher component is located at the first end of the rotating component. It can push the cryopreservation tube in the first receiving groove into the cryopreservation tube sleeve in the second receiving groove. The first receiving groove and the second receiving groove have a first station and a second station distributed at intervals along the rotation direction of the rotating component. When both the first receiving groove and the second receiving groove are in the first station, the first receiving groove and the second receiving groove are respectively connected to the first delivery port and the second delivery port, so that the cryopreservation tube in the first delivery port and the cryopreservation tube sleeve in the second delivery port are respectively moved into the first receiving groove and the second receiving groove. When both the first receiving groove and the second receiving groove are in the second station, the first pusher component can load the cryopreservation tube in the first receiving groove into the cryopreservation tube sleeve in the second receiving groove. Through this setting, the synchronous loading and unloading of cryopreservation tubes and cryopreservation tube sleeves are realized, simplifying the cryopreservation tube loading process, saving labor and time costs, and greatly improving the loading efficiency of cryopreservation tubes.

[0018] Furthermore, the present invention includes multiple first and second receiving slots, distributed circumferentially along the rotating member. The circumferential distance between two adjacent first receiving slots and the circumferential distance between two adjacent second receiving slots are both equal to the circumferential distance between the first and second workstations. This arrangement allows two adjacent receiving slots to be simultaneously located at the first and second workstations, enabling tube lowering and loading operations to be performed in the two slots respectively. By controlling the orderly switching of the receiving slots between the first and second workstations, a streamlined loading operation for multiple cryopreservation tube sleeves is achieved, further improving the loading efficiency of cryopreservation tubes.

[0019] Furthermore, the present invention has at least three first and two receiving tanks, and each of the first and second receiving tanks also has a third station. The first, second, and third stations are sequentially spaced along the rotation direction of the rotating member, and the circumferential distance between the third station and the second station is equal to the circumferential distance between the first and second stations. The filling device also includes a second push tube member installed on the fixed member. The second push tube member is located at the first end of the rotating member and can pass through the first receiving tank and extend into the second receiving tank so that at least a portion of the cryopreservation tube sleeve in the second receiving tank extends out from the second end of the second receiving tank. When both the first and second receiving tanks are located at the third station, the second end of the first receiving tank is directly opposite the second push tube member. With this setup, on the one hand, the filled cryopreservation tube sleeves can be pushed out from the second end of the second receiving tank, facilitating the further extraction and collection of the filled cryopreservation tube sleeves; on the other hand, by simultaneously lowering, transferring, loading, and pushing cryopreservation tubes and cryopreservation tube sleeves, a streamlined filling operation for multiple cryopreservation tube sleeves is achieved, improving the automation level of the entire filling process and further enhancing the filling efficiency of cryopreservation tubes.

[0020] Furthermore, the first pusher component and the second pusher component of the present invention are fixedly connected or integrally formed. This arrangement allows the first pusher component and the second pusher component to move synchronously, enabling simultaneous loading and pushing operations in two adjacent receiving slots. This facilitates faster turnover of cryopreservation tubes and cryopreservation tube sleeves and shortens the filling time.

[0021] Furthermore, the filling device of the present invention also includes a guiding mechanism, which is installed between the fixed member and the first and / or second pusher members. The guiding mechanism guides the first and second pusher members during their movement relative to the fixed member, enabling them to move along the first receiving groove. This arrangement ensures stable movement of the first and second pusher members within the receiving groove, guaranteeing stability during the filling and pushing process.

[0022] Furthermore, the first push tube component of the present invention is a first push rod, and the second push tube component is a second push rod. The length of the second push rod is greater than the length of the first push rod. The filling device also includes a connecting frame. The first end of the first push rod and the first end of the second push rod are fixedly connected through the connecting frame. The fixing component is provided with a first through hole and a second through hole at positions corresponding to the first push rod and the second push rod, respectively. The second end of the first push rod and the second end of the second push rod are located in the first through hole and the second through hole, respectively. When the first receiving groove is located at the second station, the second end of the first receiving groove is directly opposite the first through hole. When the first receiving groove is located at the third station, the second end of the first receiving groove is directly opposite the second through hole. The guiding mechanism includes a first guiding component and a second guiding component that cooperate with each other. The first guiding component is fixedly connected to the fixing component, and the second guiding component is fixedly connected to the connecting frame. With this configuration, the connecting frame can connect and fix the first push rod and the second push rod, thereby strengthening the structure after connection and improving their overall integrity. The first and second through holes facilitate the entry of the first and second push rods into the receiving slot. At the same time, when the first and second push rods move synchronously, the second push rod can extend a greater distance than the first push rod, so as to push the cryopreservation tube sleeve forward and push at least a portion of the cryopreservation tube sleeve out of the second receiving slot, thus facilitating the extraction and collection of the cryopreservation tube sleeve.

[0023] Furthermore, the filling device of the present invention also includes a tube unloading component fixed to the fixed component. The tube unloading component is located at the second end of the rotating component. The tube unloading component can stop the portion of the cryopreservation tube sleeve exposed outside the second receiving tank during the rotation of the rotating component, so as to separate the cryopreservation tube sleeve from the second receiving tank. Alternatively, the filling device also includes a drive mechanism fixedly connected to the rotating component. The drive mechanism can drive the rotating component to rotate forward, and the circumferential displacement of the rotating component driven by the drive mechanism each time is equal to the circumferential distance between the first and second stations, so that the first and second receiving tanks can accurately rotate to the first, second, or third station as the rotating component rotates. With this configuration, on the one hand, it facilitates the extraction and collection of the filled cryopreservation tube sleeves and empties the second receiving tank, allowing it to enter the next filling process for tube placement, thus improving the automation level of the filling device. On the other hand, precise control of the rotation angle of the rotating component each time is achieved, thereby achieving precise positioning of the receiving tank, ensuring that each rotation of the receiving tank stops precisely at any station, eliminating the docking process between the receiving tank and each station, and reducing the operational difficulty of the equipment.

[0024] Furthermore, the driving mechanism of the present invention includes a first ratchet, a pressure rod assembly, a second ratchet, and a pawl. The first ratchet is fixedly connected to the rotating member. The pressure rod assembly is mounted on the fixed member and can move up and down relative to the fixed member in the vertical direction. The first ratchet has a plurality of first ratchet teeth distributed circumferentially, and the number of first ratchet teeth is equal to the number of first receiving slots. The bottom end of the pressure rod assembly can abut against the first ratchet teeth to drive the first ratchet to rotate. Each time the pressure rod assembly drives the first ratchet to rotate the rotating member in the forward direction, the circumferential displacement is equal to the circumferential distance between the first station and the second station, so that the first receiving slot and the second receiving slot can accurately rotate to the first station, the second station, or the third station as the rotating member rotates. The second ratchet is fixedly connected to the rotating member, and the pawl is pivotally connected to the fixed member. The second ratchet has a plurality of second ratchet teeth distributed circumferentially, and the pawl can provide one-way stop to the second ratchet teeth to prevent the rotating member from rotating in the reverse direction. This design enables precise positioning and limiting of the rotating components, allowing them to move any receiving slot to any workstation and ensure that the receiving slot stops at any workstation. This facilitates pipe dropping, pipe loading, or pipe pushing, further reducing operational difficulty.

[0025] Furthermore, the pressure bar assembly of the present invention includes a pressure bar and a spring. The spring is fixed vertically to a fixing member, the pressure bar passes through the spring, the top end of the pressure bar is fixedly connected to the top end of the spring, and the bottom end of the pressure bar can abut against a first ratchet to drive a first ratchet to rotate. The spring can apply an upward thrust to the pressed pressure bar to reset it. This design allows the pressure bar to automatically reset after each press, eliminating the need for manual lifting and resetting, further improving the automation level of the filling equipment.

[0026] Furthermore, the rotating component of the present invention includes a first rotating component and a second rotating component, and the filling device further includes a rotating shaft and a conduit component mounted on a fixed component. The rotating shaft is rotatable relative to the fixed component. The first rotating component and the second rotating component are both fixedly connected to the rotating shaft and are spaced apart along the axial direction of the rotating shaft. The first rotating component is located below the first dispensing port, and the second rotating component is located below the second dispensing port. The first receiving groove is located on the outer peripheral surface of the first rotating component, and the second receiving groove is located on the outer peripheral surface of the second rotating component. The conduit component is located between the first rotating component and the second rotating component. When the first receiving groove and the second receiving groove are located at the second working position, the two ends of the conduit component are respectively connected to the first end of the first receiving groove and the first end of the second receiving groove. And / or, each of the first dispensing ports has an inclined first guide portion to guide the cryopreservation tube in the first dispensing port to the bottom of the first dispensing port; and / or, each of the second dispensing ports has an inclined second guide portion to guide the cryopreservation tube in the second dispensing port to the bottom of the second dispensing port. This design reduces the processing difficulty of the rotating components, facilitates individual repair and replacement of different components, improves equipment maintainability, and effectively controls the production and usage costs of the equipment. On the other hand, it facilitates the batch delivery of cryopreservation tubes and cryopreservation tube sleeves, and guides them to the rotating components below in an orderly manner, avoiding blockage of the delivery port and ensuring smooth tube delivery. Attached Figure Description

[0027] The preferred embodiments of the present invention are described below with reference to the accompanying drawings, in which:

[0028] Figure 1 This is a schematic diagram of the structure of the cryopreservation tube filling device of the present invention. Figure 1 ;

[0029] Figure 2 This is a schematic diagram of the structure of the cryopreservation tube filling device of the present invention. Figure 2 ;

[0030] Figure 3 This is a schematic diagram of the structure of the cryopreservation tube filling device of the present invention. Figure 3 ;

[0031] Figure 4 This is a schematic diagram of the structure of the cryopreservation tube filling device of the present invention. Figure 4 ;

[0032] Figure 5 This is a schematic diagram of the structure of the cryopreservation tube filling device of the present invention. Figure 5 ;

[0033] Figure 6 This is a schematic diagram of the drive mechanism of the present invention. Figure 1 ;

[0034] Figure 7 yes Figure 6 A magnified view of a portion of the image;

[0035] Figure 8 This is a schematic diagram of the drive mechanism of the present invention. Figure 2 ;

[0036] Figure 9 yes Figure 8 A magnified view of a portion of the image.

[0037] List of reference numerals in the attached diagram:

[0038] 1. Fixing component; 11. First delivery port; 12. Second delivery port; 13. Receiving cavity; 2. Rotating component; 21. First receiving groove; 22. Second receiving groove; 23. First rotating component; 24. Second rotating component; 31. First push tube component; 32. Second push tube component; 33. Connecting frame; 4. Guiding mechanism; 5. Unloading component; 6. Driving mechanism; 61. First ratchet; 611. First ratchet tooth; 62. Second ratchet; 621. Second ratchet tooth; 631. Pressure rod; 632. Spring; 64. Pawl; 7. Rotating shaft; 8. Conduit component; 91. Cryopreservation tube; 92. Cryopreservation tube sleeve. Detailed Implementation

[0039] Preferred embodiments of the present invention will now be described with reference to the accompanying drawings. Those skilled in the art should understand that these embodiments are merely illustrative of the technical principles of the present invention and are not intended to limit the scope of protection of the present invention.

[0040] It should be noted that in the description of this invention, terms such as "inner," "outer," "upper," "lower," "top," and "bottom," which indicate direction or positional relationships, are based on the direction or positional relationships shown in the accompanying drawings. These are used merely for ease of description and do not indicate or imply that the device or element must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0041] Furthermore, it should be noted that, in the description of this invention, unless otherwise explicitly specified and limited, the terms "set," "connect," and "install" should be interpreted broadly, for example, referring to a fixed connection, a detachable connection, or an integral connection. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0042] In the prior art, as indicated in the background section, when filling cryopreservation tubes into cryopreservation tube sleeves, multiple cryopreservation tubes need to be manually placed into the sleeves sequentially, resulting in low filling efficiency and wasting time and effort. This invention provides a cryopreservation tube filling device. It aims to achieve this by arranging a rotating component, a first tube-pushing component, a receiving cavity, and a first and second dispensing ports communicating with the receiving cavity on a fixed component. The rotating component is pivotally connected to the fixed component and rotates within the receiving cavity. The rotating component has first and second receiving grooves spaced apart axially and communicating with each other. The first and second receiving grooves can reach first and second stations spaced apart along the rotation direction of the rotating component as the rotating component rotates. At the first station, the two receiving grooves are respectively connected to the two dispensing ports. At the second station, the second end of the first receiving groove faces the first tube-pushing component, allowing the first tube-pushing component to extend into the first receiving groove to push the tube. This arrangement enables batch filling of cryopreservation tubes, effectively improving the filling efficiency.

[0043] Specifically, such as Figures 1 to 4 As shown, the filling device of the present invention includes a fixed component 1, a rotating component 2 and a first pusher component 31 mounted on the fixed component 1. The fixed component 1 has a receiving cavity 13 and a first delivery port 11 and a second delivery port 12 communicating with the receiving cavity 13. The first delivery port 11 and the second delivery port 12 are spaced apart along the axial direction of the rotating component 2. The rotating component 2 is located inside the receiving cavity 13 and is pivotally connected to the fixed component 1. The outer peripheral surface of the rotating component 2 is in contact with the inner peripheral surface of the receiving cavity 13. The outer peripheral surface of the rotating component 2 has a first receiving groove 21 and a second receiving groove 22 extending along the axial direction of the rotating component 2. The first receiving groove 21 can simultaneously accommodate multiple cryopreservation tubes 91, and the second receiving groove 22 can accommodate one cryopreservation tube sleeve 92. The first end of the first receiving groove 21 is connected to the first end of the second receiving groove 22. The first pusher component 31... The tube component 31 is located at the first end of the rotating component 2 and can push the cryopreservation tube 91 in the first receiving groove 21 into the cryopreservation tube sleeve 92 in the second receiving groove 22. The first receiving groove 21 and the second receiving groove 22 have a first working position and a second working position distributed at intervals along the rotation direction of the rotating component 2. When the first receiving groove 21 and the second receiving groove 22 are both located at the first working position, the first receiving groove 21 and the second receiving groove 22 are respectively connected to the first delivery port 11 and the second delivery port 12, so that the cryopreservation tube 91 in the first delivery port 11 and the cryopreservation tube sleeve 92 in the second delivery port 12 are respectively moved into the first receiving groove 21 and the second receiving groove 22. When the first receiving groove 21 and the second receiving groove 22 are both located at the second working position, the first tube pushing component 31 can load the cryopreservation tube in the first receiving groove 21 into the cryopreservation tube sleeve in the second receiving groove 22.

[0044] For example, the fixing component 1 is configured as a box structure, a fixing seat, or a mounting bracket, which can install various components on the loading equipment and support and protect each component. The fixing component 1 can be configured as a single piece or as an assembly of several components. At the same time, according to the installation needs of the internal components, the fixing component 1 is also divided into multiple installation spaces. The first delivery port 11 and the second delivery port 12 are located on the top of the fixing component 1, and the receiving cavity 13 is located below the first delivery port 11 and the second delivery port 12. The advantage of this is that when the first receiving groove 21 and the second receiving groove 22 are located at the first working position, the cryopreservation tube 91 and the cryopreservation tube sleeve 92 can move from the first delivery port 11 and the second delivery port 12 to the first receiving groove 21 and the second receiving groove 22 respectively without the need for external force.

[0045] The receiving cavity 13 is configured as a cylindrical cavity, and correspondingly, the rotating component 2 is also configured as a cylinder. The first delivery port 11 and the second delivery port 12, the first receiving groove 21 and the second receiving groove 22 all extend along the axial direction of the receiving cavity 13. The connected first receiving groove 21 and the second receiving groove 22 pass through both ends of the rotating component 2. The first receiving groove 21 and the second receiving groove 22 have a first groove and a second groove on the outer peripheral surface of the rotating component 2. The cryopreservation tube 91 and the cryopreservation tube sleeve 92 can not only enter and exit the first receiving groove 21 and the second receiving groove 22 from the first groove and the second groove respectively, but also enter and exit the first receiving groove 21 and the second receiving groove 22 from both ends of the rotating component 2.

[0046] The first receiving trough 21 is located below the first delivery port 11, and the second receiving trough 22 is located below the second delivery port 12. This allows the first receiving trough 21 and the second receiving trough 22 to simultaneously receive cryopreservation tubes 91 and cryopreservation tube sleeves 92 delivered from the first delivery port 11 and the second delivery port 12, respectively. It should be noted that the size of the first receiving trough 21 is preferably set to be equal to the capacity of the cryopreservation tube sleeve 92, and the second receiving trough 22 can accommodate a single cryopreservation tube sleeve 92, so that the number of cryopreservation tubes 91 transferred by the first receiving trough 21 each time can exactly fill a cryopreservation tube sleeve 92.

[0047] In addition, the first delivery port 11 and the second delivery port 12 are preferably located directly above the rotating member 2 to facilitate the downward movement of the cryopreservation tube 91 and the cryopreservation tube sleeve 92 and accelerate the speed of tube dropping.

[0048] When the first delivery port 11 and the second delivery port 12 are located at the first work station and the first tube pusher 31 is located at the second work station, the first receiving tank 21 and the second receiving tank 22 can be driven to reach the first work station or the second work station at the same time by driving the rotating component 2 to perform tube lowering and tube loading operations.

[0049] This enables the simultaneous lowering and loading of cryopreservation tubes 91 and cryopreservation tube sleeves 92, simplifies the filling process of cryopreservation tubes 91, saves labor and time costs, and greatly improves the filling efficiency of cryopreservation tubes 91.

[0050] Preferably, such as Figures 1 to 4 As shown, the number of first receiving grooves 21 and second receiving grooves 22 in this invention are both multiple and are distributed at intervals along the circumference of the rotating member 2. The circumferential distance between two adjacent first receiving grooves 21 and the circumferential distance between two adjacent second receiving grooves 22 are both equal to the circumferential distance between the first station and the second station.

[0051] For example, the number of first receiving slots 21 and second receiving slots 22 are set to multiple, and they are arranged at equal intervals on the outer circumferential surface of the rotating member 2. At the same time, since the circumferential distance between adjacent receiving slots is equal to the circumferential distance between two workstations, it is realized that when any first receiving slot 21 and any second receiving slot 22 are simultaneously located at the first workstation, the adjacent first receiving slot 21 and second receiving slot 22 are simultaneously located at the second workstation, so that pipe laying and pipe loading operations can be performed in the two adjacent sets of receiving slots respectively, and the receiving slots can be switched in an orderly manner between the first workstation and the second workstation by controlling the rotation of the rotating member 2.

[0052] This not only enables the batch transfer and filling of cryopreservation tubes 91 into cryopreservation tube sleeves 92, but also enables the streamlined filling operation of multiple cryopreservation tube sleeves 92, further improving the transfer and filling efficiency of cryopreservation tubes 91.

[0053] Preferably, such as Figures 1 to 4 As shown, the number of the first receiving groove 21 and the second receiving groove 22 of the present invention is at least three. The first receiving groove 21 and the second receiving groove 22 also have a third station. The first station, the second station and the third station are distributed sequentially at intervals along the rotation direction of the rotating member 2, and the circumferential distance between the third station and the second station is equal to the circumferential distance between the first station and the second station. The filling device of the present invention also includes a second push tube member 32 installed on the fixed member 1. The second push tube member 32 is located at the first end of the rotating member 2 and can pass through the first receiving groove 21 and extend into the second receiving groove 22 so that at least a part of the cryopreservation tube sleeve 92 in the second receiving groove 22 extends out from the second end of the second receiving groove 22. When the first receiving groove 21 and the second receiving groove 22 are both located at the third station, the second end of the first receiving groove 21 is directly opposite the second push tube member 32.

[0054] Preferably, such as Figures 1 to 4As shown, the number of the first receiving groove 21 and the second receiving groove 22 are each set to six, and they are equally spaced on the outer circumferential surface of the rotating member 2. The circumferential distance between the first station and the second station, and the circumferential distance between the second station and the third station are equal to the circumferential distance between any two adjacent sets of receiving grooves. The second push tube member 32 is located at the third station.

[0055] This allows the three adjacent first receiving slots 21 to be located simultaneously at the first, second, and third workstations, and correspondingly, the three adjacent second receiving slots 22 are also located simultaneously at the first, second, and third workstations.

[0056] On the one hand, the filled cryopreservation tube sleeve 92 can be pushed out from the second end of the second receiving tank 22, which facilitates the further extraction and collection of the filled cryopreservation tube sleeve 92; on the other hand, by simultaneously lowering, transferring, loading and pushing cryopreservation tubes 91 and cryopreservation tube sleeves 92, the automated filling of multiple cryopreservation tube sleeves 92 is realized, and the automation level of the entire filling process is improved, further improving the filling efficiency of cryopreservation tubes 91.

[0057] Preferably, such as Figure 1 , Figure 3 and Figure 4 As shown, the first push tube component 31 and the second push tube component 32 of the present invention are fixedly connected or integrally formed.

[0058] This configuration allows the first push tube component 31 and the second push tube component 32 to move synchronously, enabling the tube loading action in the previous receiving tank to be synchronized with the tube pushing action in the next receiving tank. It also allows for rapid connection between the lowering and loading of tubes in the same receiving tank, which helps to accelerate the circulation speed of the cryopreservation tube 91 and the cryopreservation tube sleeve 92 and shorten the filling time.

[0059] Preferably, such as Figure 1 and Figure 4 As shown, the filling device of the present invention further includes a guiding mechanism 4, which is installed between the fixed member 1 and the first push tube member 31 and / or the second push tube member 32. The guiding mechanism 4 can guide the first push tube member 31 and the second push tube member 32 during the movement of the first push tube member 31 and the second push tube member 32 relative to the fixed member 1 so that the first push tube member 31 and the second push tube member 32 can move along the first receiving groove 21.

[0060] In a preferred embodiment, the guiding mechanism 4 includes a guide rail extending along the axial direction of the rotating member 2 and a guide wheel cooperating with the guide rail. The first tube pushing member 31 and / or the second tube pushing member 32 are fixedly connected to the guide rail and move along the guiding direction of the guide rail, thereby enabling both to simultaneously enter two adjacent first receiving slots 21 for tube loading and tube pushing operations respectively.

[0061] In another preferred embodiment, the guiding mechanism 4 includes a fixed base and a first guide hole and a second guide hole disposed on the fixed base. The first guide hole and the second guide hole are located at the second work station and the third work station, respectively, so as to communicate with two adjacent sets of receiving slots. The first push tube component 31 and the second push tube component 32 are slidably connected in the first guide hole and the second guide hole, respectively, thereby realizing the stable movement of the first push tube component 31 and the second push tube component 32 in the two adjacent sets of receiving slots, ensuring the stability during the tube loading and pushing process.

[0062] Preferably, such as Figures 1 to 4 As shown, the first push tube component 31 of the present invention is a first push rod, and the second push tube component 32 is a second push rod. The length of the second push rod is greater than the length of the first push rod. The filling device of the present invention also includes a connecting frame 33. The first end of the first push rod and the first end of the second push rod are fixedly connected through the connecting frame 33. The fixing component 1 is provided with a first through hole and a second through hole at positions corresponding to the first push rod and the second push rod, respectively. The second end of the first push rod and the second end of the second push rod are located in the first through hole and the second through hole, respectively. When the first receiving groove 21 is located at the second station, the second end of the first receiving groove 21 is directly opposite the first through hole. When the first receiving groove 21 is located at the third station, the second end of the first receiving groove 21 is directly opposite the second through hole. The guiding mechanism 4 includes a first guiding component and a second guiding component that cooperate with each other. The first guiding component is fixedly connected to the fixing component 1, and the second guiding component is fixedly connected to the connecting frame 33.

[0063] For example, the first end of the first push tube component 31 is flush with the first end of the second push tube component 32, and the connecting frame 33 connects and fixes the first end of the first push tube component 31 and the first end of the second push tube component 32, so that the two are integrated into one, thereby improving their structural strength.

[0064] The first and second through holes facilitate the entry of the first and second push rods into the receiving groove, and also serve as guides and supports for the first and second push rods, further improving the stability of the first and second push rods during operation.

[0065] Since the length of the second push tube member 32 is greater than the length of the first push tube member 31, the second end of the second push tube member 32 can enter the receiving groove a greater distance than the second end of the first push tube member 31.

[0066] Therefore, when the first push rod and the second push rod are pushed to their ends simultaneously, the second end of the first push rod can only reach between the first receiving groove 21 and the second receiving groove 22, so that the cryopreservation tube 91 in the first receiving groove 21 is completely pushed into the cryopreservation tube sleeve 92 in the second receiving groove 22. The second end of the second push rod can pass through the first receiving groove 21 and extend into the second receiving groove 22, thereby pushing the cryopreservation tube sleeve 92 towards the second end of the second receiving groove 22, so that a part of the cryopreservation tube sleeve 92 filled with cryopreservation tube 91 is exposed outside the second receiving groove 22, so as to facilitate the next step of extraction and collection of the cryopreservation tube sleeve 92.

[0067] In this invention, the first guide member is preferably a slide rail, the second guide member is preferably a pulley, and one of the slide rail and the pulley is mounted on the fixed member 1, while the other of the slide rail and the pulley is mounted on the connecting frame 33.

[0068] Preferably, such as Figures 1 to 5 As shown, the filling device of the present invention also includes a tube unloading component 5 fixed on the fixing component 1. The tube unloading component 5 is located at the second end of the rotating component 2. The tube unloading component 5 can stop the part of the cryopreservation tube sleeve 92 exposed outside the second receiving groove 22 during the rotation of the rotating component 2, so as to separate the cryopreservation tube sleeve 92 from the second receiving groove 22.

[0069] Specifically, after the cryopreservation tube sleeve 92 filled with cryopreservation tubes 91 is partially pushed out by the second push rod at the third station, it continues to rotate with the rotating component 2. When the cryopreservation tube sleeve 92 rotates to the unloading component 5, the unloading component 5 is preferably located at a position away from the opening of the receiving tank. As the rotating component 2 continues to move, the unloading component 5 will apply a pushing force from the inside out towards the opening of the tank to push the cryopreservation tube sleeve 92 out of the receiving tank, thereby realizing the separation of the cryopreservation tube sleeve 92 from the rotating device.

[0070] This enables the automatic separation of the cryopreservation tube sleeve 92 from the receiving tank, facilitating the extraction and collection of the filled cryopreservation tube sleeve 92, and freeing up the second receiving tank 22 to continue receiving the cryopreservation tube sleeve 92 falling from the second delivery port 12 in the next filling process, thereby improving the automation level of the filling equipment.

[0071] Preferably, such as Figures 1 to 5 As shown, the filling device of the present invention also includes a drive mechanism 6 fixedly connected to the rotating member 2. The drive mechanism 6 can drive the rotating member 2 to rotate in the forward direction, and the circumferential displacement of the rotating member 2 driven by the drive mechanism 6 each time is equal to the circumferential distance between the first station and the second station, so that the first receiving groove 21 and the second receiving groove 22 can accurately rotate to the first station, the second station or the third station as the rotating member 2 rotates.

[0072] The drive mechanism 6 can drive the rotating component 2. Each drive can make the rotating component 2 rotate through a fixed angular displacement, thereby achieving precise control of the rotation angle of the rotating component 2 each time. This enables precise positioning of the first receiving groove 21 and the second receiving groove 22, so that the first receiving groove 21 and the second receiving groove 22 can stop exactly at any work position after each rotation. This reduces the difficulty of docking the receiving groove with each work position, and makes the operation of the equipment simpler and faster.

[0073] It should be noted that, in practical applications, those skilled in the art can set the drive mechanism 6 in various structural forms, such as a turntable or rotating arm with a positioning block, or a ratchet and pawl assembly, or a stepper motor, as long as it can drive the rotating component 2 to rotate and be positioned. Such flexible adjustments and changes do not deviate from the principles and scope of the present invention and should all be limited to the protection scope of the present invention.

[0074] Preferably, such as Figures 6 to 9 As shown, the driving mechanism 6 of the present invention includes a first ratchet 61, a pressure bar assembly, a second ratchet 62, and a pawl 64. The first ratchet 61 is fixedly connected to the rotating member 2. The pressure bar assembly is mounted on the fixed member 1 and can move up and down relative to the fixed member 1 in the vertical direction. The first ratchet 61 has a plurality of first ratchet teeth 611 distributed circumferentially, and the number of first ratchet teeth 611 is equal to the number of first receiving grooves 21. The bottom end of the pressure bar assembly can abut against the first ratchet teeth 611 to drive the first ratchet 61 to rotate. The pressure bar assembly drives the first ratchet 62 each time. The circumferential displacement of the rotating component 2 driven by the ratchet 61 in the forward rotation is equal to the circumferential distance between the first and second work positions, so that the first receiving groove 21 and the second receiving groove 22 can accurately rotate to the first work position, the second work position or the third work position as the rotating component 2 rotates. The second ratchet 62 is fixedly connected to the rotating component 2, and the pawl 64 is pivotally connected to the fixed component 1. The second ratchet 62 has a plurality of second ratchet teeth 621 distributed circumferentially. The pawl 64 can unidirectionally stop the second ratchet teeth 621 to prevent the rotating component 2 from rotating in the reverse direction.

[0075] For example, the first ratchet 61 and the second ratchet 62 are fixedly connected or integrally formed, and both are fixedly connected to the rotating shaft 7. In the axial direction of the rotating shaft 7, the first ratchet 61 is located on the outer side, and the second ratchet 62 is located on the inner side. At the same time, in order to prevent mutual interference, the first ratchet tooth 611 is circumferentially arranged on the end face of the first ratchet 61. The pressure bar assembly is located on the outer side of the end face and cooperates with the first ratchet tooth 611. The second ratchet tooth 621 is circumferentially arranged on the outer circumferential surface of the second ratchet 62. One end of the pawl 64 is pivotally connected to the fixing member 1, and the other end of the pawl 64 cooperates with the second ratchet tooth 621 to stop, which can realize the one-way stop of the second ratchet 62.

[0076] Specifically, the number of first ratchet teeth 611, first receiving grooves 21, and second receiving grooves 22 are the same. The bottom end of the pressure bar assembly drives the first ratchet wheel 61 to rotate forward by engaging with the first ratchet teeth 611. The pressure bar assembly has an upper dead center and a lower dead center. During the driving process, the pressure bar assembly can move from the upper dead center to the lower dead center under the action of external force, thereby completing the driving of one first ratchet tooth 611, causing the first ratchet wheel 61 to rotate through a certain angular displacement. Then, the pressure bar assembly is lifted up from the lower dead center and reset to the upper dead center. During this process, the bottom end of the pressure bar assembly moves from the previous first ratchet 611 to the adjacent first ratchet 611 to drive the first ratchet 61 again. This means that each press of the pressure bar assembly completes one drive of the first ratchet 61, thereby driving the first ratchet 61 to rotate through a certain angle. By repeatedly pressing the pressure bar assembly, the first ratchet 61 will rotate step by step at a certain angle, and the angular displacement of the first ratchet 61's rotation step is equal to the angular displacement between any two sets of receiving grooves.

[0077] During the process of resetting the pressure bar assembly upwards, the pressure bar assembly will generate a reverse thrust on the first ratchet 611, causing the first ratchet 61 to tend to rotate in the opposite direction, which will affect the positioning accuracy of the rotating component 2. The pawl 64 is designed to allow the second ratchet 62 to rotate in the forward direction while preventing the second ratchet 62 from rotating in the reverse direction. Therefore, the reverse stop action of the pawl 64 on the second ratchet 621 can limit the rotating component 2, so that the receiving groove can stop precisely at any position to ensure the positioning accuracy of the rotating component 2, thereby ensuring the docking accuracy between the receiving groove and any position.

[0078] This setup enables precise positioning and limiting of the rotating component 2, allowing it to rotate any receiving slot to any workstation and ensure that the receiving slot stops at any workstation. This facilitates the pipe dropping, loading, and pushing of the filling equipment, further reducing operational difficulty.

[0079] Preferably, such as Figure 2 , Figures 5 to 9 As shown, the pressure bar assembly of the present invention includes a pressure bar 631 and a spring 632. The spring 632 is fixed to the fixing member 1 in the vertical direction. The pressure bar 631 passes through the spring 632. The top end of the pressure bar 631 is fixedly connected to the top end of the spring 632. The bottom end of the pressure bar 631 can abut against the first ratchet 611 to drive the first ratchet 61 to rotate. The spring 632 can apply an upward thrust to the pressure bar 631 to reset the pressure bar 631.

[0080] During the downward pressing of the lever 631, since the lower part of the spring 632 is fixedly connected to the fixed component 1, the top of the lever 631 will drive the top of the spring 632 to move downward, so that the spring 632 is gradually compressed until the lever 631 is pressed to the lower stop point. At this time, the lever 631 is released to make the external force disappear, and the lever 631 will rebound upward to the upper stop point under the action of the spring 632. This allows the lever 631 to rebound from the lower stop point to the upper stop point after each pressing, without the need for manual lifting and reset, which further improves the operation frequency and automation of the filling equipment.

[0081] Preferably, such as Figures 1 to 3 As shown, the rotating component 2 of the present invention includes a first rotating component 23 and a second rotating component 24. The filling device of the present invention also includes a rotating shaft 7 and a conduit component 8 mounted on the fixed component 1. The rotating shaft 7 is rotatable relative to the fixed component 1. The first rotating component 23 and the second rotating component 24 are both fixedly connected to the rotating shaft 7 and are distributed at intervals along the axial direction of the rotating shaft 7. The first rotating component 23 is located below the first injection port 11, and the second rotating component 24 is located below the second injection port 12. The first receiving groove 21 is located on the outer peripheral surface of the first rotating component 23, and the second receiving groove 22 is located on the outer peripheral surface of the second rotating component 24. The conduit component 8 is located between the first rotating component 23 and the second rotating component 24. When the first receiving groove 21 and the second receiving groove 22 are located at the second working position, the two ends of the conduit component 8 are respectively connected to the first end of the first receiving groove 21 and the first end of the second receiving groove 22. And / or, the first delivery port 11 has an inclined first guide portion to guide the cryopreservation tube 91 in the first delivery port 11 to the bottom of the first delivery port 11; and / or, the second delivery port 12 has an inclined second guide portion to guide the cryopreservation tube sleeve 92 in the second delivery port 12 to the bottom of the second delivery port 12.

[0082] For example, the first rotating component 23 and the second rotating component 24 are set as independent components, and the two are fixedly connected by the rotating shaft 7. This helps to reduce the processing difficulty of the rotating component 2, facilitates the individual maintenance and replacement of different components in the later stage, improves the maintainability of the equipment, and effectively controls the production and use costs of the equipment.

[0083] Meanwhile, the first rotating component 23 and the second rotating component 24 are spaced a certain distance apart in the axial direction, so that the first receiving groove 21 and the second receiving groove 22 are not directly connected and there is a certain gap between them. When the first receiving groove 21 and the second receiving groove 22 are in the second working position, the cryopreservation tube 91 moves from the first receiving groove 21 to the second receiving groove 22 under the push of the first push tube component 31. When the cryopreservation tube 91 moves to the gap between the first receiving groove 21 and the second receiving groove 22, the multiple cryopreservation tubes 91 lose the external force constraint along the radial inward direction, causing the ends of the cryopreservation tubes 91 to spread out in all directions, making it impossible to smoothly enter the second receiving groove 22.

[0084] To solve this problem, the conduit component 8 has a circular through hole. The first end of the circular through hole is connected to the first end of the first receiving groove 21, and the second end of the circular through hole is connected to the first end of the second receiving groove 22. The inner diameter of the first end of the circular through hole is not less than the inner diameter of the first receiving groove 21, and the inner diameter of the second end of the circular through hole is not greater than the inner diameter of the second receiving groove 22, so that the cryopreservation tube 91 can be smoothly introduced from the first receiving groove 21 into the second receiving groove 22.

[0085] Furthermore, both the first and second guide sections are two opposing inclined surfaces. The two inclined surfaces of the first guide section slope inward from top to bottom and extend to the first delivery port 11, so that the spacing at the first delivery port 11 only allows one cryopreservation tube 91 to pass through, while the top of the two inclined surfaces forms a large opening. Similarly, the two inclined surfaces of the second guide section slope inward from top to bottom and extend to the second delivery port 12, so that the spacing at the second delivery port 12 only allows one cryopreservation tube sleeve 92 to pass through, while the top of the two inclined surfaces forms a large opening. This arrangement is conducive to the batch delivery of cryopreservation tubes 91 and cryopreservation tube sleeves 92, so as to guide the cryopreservation tubes 91 and cryopreservation tube sleeves 92 to the rotating component 2 below in an orderly manner, and can also avoid blockage of the delivery port, ensuring smooth tube delivery.

[0086] The technical solution of the present invention has been described above with reference to the preferred embodiments shown in the accompanying drawings. However, it will be readily understood by those skilled in the art that the scope of protection of the present invention is obviously not limited to these specific embodiments. Without departing from the principles of the present invention, those skilled in the art can make equivalent changes or substitutions to the relevant technical features, and the technical solutions after such changes or substitutions will all fall within the scope of protection of the present invention.

Claims

1. A filling device for cryopreservation tubes, characterized in that, The loading device includes a fixed component, a rotating component mounted on the fixed component, and a first pusher component. The fixed member has a receiving cavity and a first delivery port and a second delivery port communicating with the receiving cavity. The first delivery port and the second delivery port are distributed at intervals along the axial direction of the rotating member. The rotating member is located in the receiving cavity and is pivotally connected to the fixed member. The outer peripheral surface of the rotating member is in contact with the inner peripheral surface of the receiving cavity. The rotating component includes a first rotating component and a second rotating component. The outer peripheral surface of the rotating component has a first receiving groove and a second receiving groove extending along the axial direction of the rotating component. The first receiving groove is located on the outer peripheral surface of the first rotating component, and the second receiving groove is located on the outer peripheral surface of the second rotating component. The first receiving groove can simultaneously accommodate multiple cryopreservation tubes, and the second receiving groove can accommodate one cryopreservation tube sleeve. The first end of the first receiving groove is connected to the first end of the second receiving groove. The first push tube component is located at the first end of the rotating component and is capable of pushing the cryopreservation tube in the first receiving groove into the cryopreservation tube sleeve in the second receiving groove; The first receiving tank and the second receiving tank have a first station and a second station spaced apart along the rotation direction of the rotating member. When the first receiving tank and the second receiving tank are both located at the first station, the first receiving tank and the second receiving tank are respectively connected to the first delivery port and the second delivery port, so that the cryopreservation tube in the first delivery port and the cryopreservation tube sleeve in the second delivery port are respectively moved into the first receiving tank and the second receiving tank. When the first receiving tank and the second receiving tank are both located at the second station, the first pushing tube member can insert the cryopreservation tube in the first receiving tank into the cryopreservation tube sleeve in the second receiving tank. The filling device further includes a second push tube component mounted on the fixed component. The second push tube component is located at the first end of the rotating component and can pass through the first receiving groove and extend into the second receiving groove so that at least a portion of the cryopreservation tube sleeve in the second receiving groove extends out from the second end of the second receiving groove. When both the first receiving tank and the second receiving tank are located at the third working position, the second end of the first receiving tank is directly facing the second push tube component.

2. The filling device according to claim 1, characterized in that, The number of the first receiving slot and the number of the second receiving slot are both multiple and they are distributed at intervals along the circumference of the rotating member. The circumferential distance between two adjacent first receiving slots and the circumferential distance between two adjacent second receiving slots are both equal to the circumferential distance between the first station and the second station.

3. The filling device according to claim 2, characterized in that, The number of the first receiving slot and the second receiving slot is at least three. The first receiving slot and the second receiving slot also have a third station. The first station, the second station and the third station are distributed sequentially at intervals along the rotation direction of the rotating component, and the circumferential distance between the third station and the second station is equal to the circumferential distance between the first station and the second station.

4. The filling device according to claim 3, characterized in that, The first push tube component is fixedly connected to the second push tube component or is integrally formed.

5. The filling device according to claim 4, characterized in that, The filling device further includes a guiding mechanism installed between the fixed member and the first push tube member and / or the second push tube member. The guiding mechanism can guide the first push tube member and the second push tube member during their movement relative to the fixed member so that the first push tube member and the second push tube member can move along the first receiving groove.

6. The filling device according to claim 5, characterized in that, The first push tube component is a first push rod, the second push tube component is a second push rod, the length of the second push rod is greater than the length of the first push rod, the filling device further includes a connecting frame, and the first end of the first push rod and the first end of the second push rod are fixedly connected through the connecting frame; The fixing member is provided with a first through hole and a second through hole at positions corresponding to the first push rod and the second push rod, respectively. The second end of the first push rod and the second end of the second push rod are located in the first through hole and the second through hole, respectively. When the first receiving groove is located at the second working position, the second end of the first receiving groove is directly opposite the first through hole. When the first receiving groove is located at the third working position, the second end of the first receiving groove is directly opposite the second through hole. The guiding mechanism includes a first guiding member and a second guiding member that cooperate with each other. The first guiding member is fixedly connected to the fixed member, and the second guiding member is fixedly connected to the connecting frame.

7. The filling device according to claim 3, characterized in that, The filling device further includes a tube unloading component fixed to the fixing member. The tube unloading component is located at the second end of the rotating member. The tube unloading component can stop the portion of the cryopreservation tube sleeve exposed outside the second receiving groove during the rotation of the rotating member, so as to separate the cryopreservation tube sleeve from the second receiving groove; and / or The filling device further includes a drive mechanism fixedly connected to the rotating component. The drive mechanism can drive the rotating component to rotate in the forward direction, and the circumferential displacement of the rotating component driven by the drive mechanism each time is equal to the circumferential distance between the first station and the second station, so that the first receiving groove and the second receiving groove can accurately rotate to the first station, the second station or the third station as the rotating component rotates.

8. The filling device according to claim 7, characterized in that, The driving mechanism includes a first ratchet, a pressure bar assembly, a second ratchet, and a pawl. The first ratchet is fixedly connected to the rotating member. The pressure bar assembly is mounted on the fixed member and can move vertically up and down relative to the fixed member. The first ratchet has a plurality of first ratchet teeth spaced apart circumferentially, and the number of first ratchet teeth is equal to the number of first receiving slots. The bottom end of the pressure bar assembly can abut against the first ratchet teeth to drive the first ratchet to rotate. Each time the pressure bar assembly drives the first ratchet to rotate the rotating member in the forward direction, the circumferential displacement is equal to the circumferential distance between the first station and the second station, so that the first receiving slot and the second receiving slot can accurately rotate to the first station, the second station, or the third station as the rotating member rotates. The second ratchet is fixedly connected to the rotating member, and the pawl is pivotally connected to the fixed member. The second ratchet has a plurality of second ratchet teeth that are spaced apart in the circumferential direction. The pawl can stop the second ratchet teeth in one direction to prevent the rotating member from rotating in the opposite direction.

9. The filling device according to claim 8, characterized in that, The pressure bar assembly includes a pressure bar and a spring. The spring is fixed to the fixed member in a vertical direction. The pressure bar passes through the spring. The top end of the pressure bar is fixedly connected to the top end of the spring. The bottom end of the pressure bar can abut against the first ratchet to drive the first ratchet to rotate. The spring can apply an upward thrust to the pressure bar when it is pressed down so that the pressure bar returns to its original position.

10. The filling device according to any one of claims 1 to 9, characterized in that, The filling device further includes a rotating shaft and a guide tube component mounted on the fixed component. The rotating shaft is rotatable relative to the fixed component. The first rotating component and the second rotating component are both fixedly connected to the rotating shaft and spaced apart along the axial direction of the rotating shaft. The first rotating component is located below the first dispensing port, and the second rotating component is located below the second dispensing port. The guide tube component is located between the first rotating component and the second rotating component. When the first receiving groove and the second receiving groove are located at the second working position, both ends of the guide tube component are connected to the first end of the first receiving groove and the first end of the second receiving groove, respectively, and / or Each of the first dispensing ports has an inclined first guide portion to guide the cryopreservation tube inside the first dispensing port to the bottom of the first dispensing port; and / or Each of the second dispensing ports has an inclined second guide portion to guide the cryopreservation tube sleeve inside the second dispensing port to the bottom of the second dispensing port.

Images