A cryopreservation device for cord blood containing cord blood stem cells

Abstract

The utility model discloses a kind of umbilical cord blood sample's cryopreservation device containing umbilical cord blood stem cells, it is related to cryopreservation device technical field.The utility model includes: thermos and sealing mechanism, the sealing mechanism includes the placement cylinder of screw thread cooperation in the upper side of the thermos, the sealing plate of elastic sliding fit in the bottom end of the placement cylinder;Storage mechanism, the storage mechanism includes the sealing plug of screw thread cooperation on the placement cylinder, the mesh cylinder of being fixed in the bottom end of the sealing plug, multiple clamping plates of elastic sliding fit in the mesh cylinder, multiple the blood sample bottle of being placed between the clamping plate.The utility model is when needed to take away blood sample bottle, screw thread is taken out storage mechanism, sealing plate elastic sliding automatically seals placement cylinder, it is convenient to reduce the probability of liquid nitrogen in thermos large amount of evaporation discharge waste, then blood sample bottle is taken away from the multiple clamping plates of elastic sliding between, it is convenient to improve the convenience of blood sample bottle positioning and taking away.

Description

Technical Field

[0001] This utility model belongs to the field of cryopreservation devices, specifically, it relates to a cryopreservation device for umbilical cord blood samples containing umbilical cord blood stem cells. Background Technology

[0002] With the development of biological technology, cell therapy is rapidly developing and becoming increasingly accepted worldwide. The essence of cell therapy lies in the acquisition and storage of living cells.

[0003] Chinese Patent CN217986483U discloses a cryopreservation device for umbilical cord blood samples containing umbilical cord blood stem cells. Paragraph 23 of the specification discloses that, firstly, umbilical cord blood is collected into a storage bottle, then the sealing and heat-insulating cap is opened from the small bottle opening by threads, and then liquid nitrogen is injected into the inner liner from the small bottle opening. The blood sample bottle is then placed into a lifting basket, and then a hook is used to hook the lifting rod. The lifting basket is then placed into the limiting grid through the small bottle opening, and then placed on the fixed base through the anti-collision ring. At this time, the anti-collision ring limits the lifting basket. Then, the sealing and heat-insulating cap is screwed onto the small bottle opening. At this time, the sealing gasket and the protruding part on the small bottle opening are squeezed to seal. At the same time, the heat insulation block penetrates through the bottom of the small bottle opening, which plays a role in sealing and heat insulation. Meanwhile, the vacuum isolation layer inside the inner liner provides sufficient heat insulation, which reduces the consumption of liquid nitrogen.

[0004] However, the aforementioned cryopreservation device for umbilical cord blood samples containing umbilical cord blood stem cells requires the sealing cap to be completely opened when taking or taking out the blood sample, which causes a large amount of liquid nitrogen to evaporate, increasing the cost of consumables.

[0005] In view of this, this utility model is proposed. Utility Model Content

[0006] The technical problem to be solved by this utility model is to overcome the shortcomings of the prior art and provide a cryopreservation device for umbilical cord blood samples containing umbilical cord blood stem cells.

[0007] To solve the above-mentioned technical problems, the basic concept of the technical solution adopted by this utility model is as follows:

[0008] A cryopreservation device for an umbilical cord blood sample containing umbilical cord blood stem cells, comprising:

[0009] A thermos flask and a sealing mechanism, wherein the sealing mechanism includes a placement cylinder threaded to the upper side of the thermos flask and a sealing plate elastically slidingly fitted to the bottom end of the placement cylinder;

[0010] The storage mechanism includes a sealing plug threaded onto the placement cylinder, a mesh cylinder fixed to the bottom end of the sealing plug, and multiple clamps elastically sliding within the mesh cylinder, with a blood sample bottle placed between the multiple clamps.

[0011] Optionally, the upper side of the placement tube is provided with a first L-shaped outward flange, and the inner wall side of the first L-shaped outward flange is provided with threads. The placement tube is threaded onto the thermos bottle through the first L-shaped outward flange.

[0012] Optionally, a plurality of first spring dampers are embedded at the bottom end of the placement cylinder, and the sealing plate is fixed to the bottom end of the plurality of first spring dampers.

[0013] Optionally, the bottom end of the placement cylinder is provided with a mounting groove corresponding to the first spring damper, and the first spring damper is fixed in the mounting groove.

[0014] Optionally, the upper end of the sealing plug is provided with a second L-shaped outer flange, the second L-shaped outer flange is threadedly engaged with the first L-shaped outer flange, the inner wall side of the second L-shaped outer flange is provided with an external thread, and the outer side of the first L-shaped outer flange is provided with an internal thread.

[0015] Optionally, a second spring damper is provided on the outer side of the clamping plate, the second spring damper is fixed on the inner wall of the mesh cylinder, and an arc-shaped outward flange is provided at the bottom end of the clamping plate.

[0016] By adopting the above technical solution, the present invention has the following beneficial effects compared with the prior art. Of course, any product implementing the present invention does not necessarily need to achieve all of the following advantages at the same time:

[0017] When the blood sample bottle needs to be removed, the sealing plug is unscrewed, the storage mechanism is taken out, and the sealing plate slides elastically to automatically seal the placement cylinder, which helps reduce the probability of a large amount of liquid nitrogen in the thermos being evaporated and wasted. Then the blood sample bottle is taken out between the multiple elastically sliding clamps, which improves the convenience of positioning and removing the blood sample bottle.

[0018] The specific embodiments of this utility model will be described in further detail below with reference to the accompanying drawings. Attached Figure Description

[0019] The accompanying drawings described below are merely some embodiments. Those skilled in the art can obtain other drawings based on these drawings without any creative effort. In the drawings:

[0020] Figure 1 This is a three-dimensional structural diagram of an embodiment of the present utility model;

[0021] Figure 2 This is a cross-sectional structural diagram of an embodiment of the present invention;

[0022] Figure 3 This is a schematic diagram of a mesh cylinder structure according to an embodiment of the present invention;

[0023] The attached diagram lists the components represented by each number as follows:

[0024] 1. Thermos bottle; 2. Sealing mechanism; 3. Placement tube; 4. Sealing plate; 5. First L-shaped outward flange; 6. First spring damper; 7. Mounting groove; 8. Storage mechanism; 9. Sealing plug; 10. Mesh tube; 11. Clamping plate; 12. Second L-shaped outward flange; 13. Second spring damper; 14. Arc-shaped outward flange; 15. Blood sample bottle.

[0025] It should be noted that these accompanying drawings and textual descriptions are not intended to limit the scope of the present invention in any way, but rather to illustrate the concept of the present invention to those skilled in the art by referring to specific embodiments. Detailed Implementation

[0026] The present invention will now be described in further detail with reference to the accompanying drawings.

[0027] Please see Figure 1-3 As shown, this embodiment provides a cryopreservation device for an umbilical cord blood sample containing umbilical cord blood stem cells, comprising:

[0028] The thermos bottle 1 and the sealing mechanism 2, the sealing mechanism 2 includes a placement tube 201 threadedly fitted to the upper side of the thermos bottle 1 and a sealing plate 202 elastically slidingly fitted to the bottom end of the placement tube 201;

[0029] The storage mechanism 3 includes a sealing plug 301 threaded onto the placement cylinder 201, a mesh cylinder 302 fixed to the bottom of the sealing plug 301, and multiple clamping plates 303 elastically slidingly fitted inside the mesh cylinder 302. A blood sample bottle 4 is placed between the multiple clamping plates 303.

[0030] When the blood sample bottle 4 needs to be removed, the sealing plug 301 is unscrewed, the storage mechanism 3 is taken out, and the sealing plate 202 slides elastically to automatically seal the placement cylinder 201, which helps to reduce the probability of a large amount of liquid nitrogen in the thermos bottle 1 being evaporated and wasted. Then the blood sample bottle 4 is taken out between the multiple elastically sliding clamps 303, which helps to improve the convenience of positioning and removing the blood sample bottle 4.

[0031] Please see Figure 2 As shown, the upper side of the placement tube 201 in this embodiment is provided with a first L-shaped outward flange 203, and the inner wall side of the first L-shaped outward flange 203 is provided with threads. The placement tube 201 is threaded onto the thermos bottle 1 through the first L-shaped outward flange 203, which facilitates the quick installation of the placement tube 201 onto the thermos bottle 1.

[0032] Please see Figure 2-3As shown, in this embodiment, a plurality of first spring dampers 204 are embedded at the bottom end of the placement cylinder 201, and the sealing plate 202 is fixed at the bottom end of the plurality of first spring dampers 204. The bottom end of the placement cylinder 201 is provided with a mounting groove 205 corresponding to the first spring damper 204. The first spring damper 204 is fixed in the mounting groove 205, so that the sealing plate 202 can automatically seal the bottom end of the placement cylinder 201 by elastic sliding through the first spring damper 204.

[0033] Please see Figure 1-2 As shown, the upper end of the sealing plug 301 in this embodiment is provided with a second L-shaped outer flange 304. The second L-shaped outer flange 304 is threadedly engaged with the first L-shaped outer flange 203. The inner wall side of the second L-shaped outer flange 304 is provided with an external thread, and the outer side of the first L-shaped outer flange 203 is provided with an internal thread, so that the sealing plug 301 can be installed on the placement cylinder 201 and seal the placement cylinder 201.

[0034] Please see Figure 1-3 As shown, in this embodiment, a second spring damper 305 is provided on the outer side of the clamping plate 303, which facilitates the positioning of the blood sample bottle 307 by the multiple clamping plates 303 through the second spring damper 305. The second spring damper 305 is fixed on the inner wall of the mesh cylinder 302. The bottom end of the clamping plate 303 is provided with an arc-shaped outward flange 306, which facilitates the blood sample bottle 307 to be squeezed into the mesh cylinder 302 by the arc-shaped outward flange 306. The upper side of the blood sample bottle 4 is in contact with the bottom surface of the sealing plug 301. The bottom end of the blood sample bottle 4 is lower than the bottom end of the mesh cylinder 302, which facilitates the handling of the blood sample bottle 4.

[0035] Working principle: Liquid nitrogen is poured into the thermos flask 1, and then the placement tube 201 is threaded onto the thermos flask 1. The sealing plate 202 initially seals the bottom of the placement tube 201. Then, the blood sample bottle 4 is squeezed into the mesh tube 302 by the curved outward flange 306. Multiple clamps 303 position the blood sample bottle 4 through the second spring damper 305. Then, the sealing plug 301 is inserted into the placement tube 201 to seal the placement tube 201, and the sealing plate 202 is squeezed to slide open the placement tube 201, stretching the first spring damper 204. The sealing plug 301 is threaded onto the placement cylinder 201. The cold air inside the blood sample bottle 4 and the thermos bottle 1 cools the blood sample bottle 4 through the mesh holes of the mesh cylinder 302. When the blood sample bottle 4 needs to be removed, the sealing plug 301 is unscrewed, the storage mechanism 3 is removed, and the first spring damper 204 stretches the sealing plate 202 to slide and automatically seal the placement cylinder 201, which helps to reduce the probability of a large amount of liquid nitrogen in the thermos bottle 1 being evaporated and wasted. Then the blood sample bottle 4 is removed from between multiple clamps 303, which helps to improve the convenience of positioning and removing the blood sample bottle 4.

[0036] The contents not described in detail in this specification are existing technologies known to those skilled in the art. All electrical appliances in this utility model are powered by an external power source or a built-in battery. No restrictions are placed on the model or specific type of any electrical appliance in this utility model. Those skilled in the art can clearly identify the applicable electrical appliance model, specific type, and power supply method based on common knowledge in the field.

[0037] This utility model is not limited to the above-described embodiments. Anyone should know that structural changes made under the guidance of this utility model, and any technical solutions that are the same as or similar to this utility model, fall within the protection scope of this utility model. Technical aspects, shapes, and structures not described in detail in this utility model are all publicly known technologies.

Claims

1. A cryopreservation device for cord blood sample containing cord blood stem cells, characterized by, include: The thermos (1) and sealing mechanism (2) include a placement tube (201) threadedly fitted on the upper side of the thermos (1) and a sealing plate (202) elastically slidingly fitted on the bottom end of the placement tube (201); The storage mechanism (3) includes a sealing plug (301) threaded onto the placement cylinder (201), a mesh cylinder (302) fixed to the bottom end of the sealing plug (301), and multiple clamping plates (303) elastically slidingly fitted inside the mesh cylinder (302). A blood sample bottle (4) is placed between the multiple clamping plates (303).

2. The umbilical cord blood sample containing umbilical cord blood stem cells for cryopreservation according to claim 1, wherein, The upper side of the placement tube (201) is provided with a first L-shaped outward flange (203), and the inner wall side of the first L-shaped outward flange (203) is provided with threads. The placement tube (201) is threaded onto the thermos bottle (1) through the first L-shaped outward flange (203).

3. The cryopreservation device for umbilical cord blood samples containing umbilical cord blood stem cells according to claim 2, characterized in that, The bottom end of the placement cylinder (201) is embedded with a plurality of first spring dampers (204), and the sealing plate (202) is fixed to the bottom end of the plurality of first spring dampers (204).

4. The umbilical cord blood sample containing umbilical cord blood stem cells for cryopreservation according to claim 3, wherein The bottom end of the placement cylinder (201) is provided with a mounting groove (205) corresponding to the first spring damper (204), and the first spring damper (204) is fixed in the mounting groove (205).

5. The umbilical cord blood sample containing umbilical cord blood stem cells for cryopreservation according to claim 4, wherein The upper end of the sealing plug (301) is provided with a second L-shaped outer flange (304), and the second L-shaped outer flange (304) is threaded onto the first L-shaped outer flange (203).

6. The umbilical cord blood sample containing umbilical cord blood stem cells for cryopreservation according to claim 5, wherein, The inner wall of the second L-shaped outer flange (304) is provided with external threads, and the outer wall of the first L-shaped outer flange (203) is provided with internal threads.

7. The umbilical cord blood sample containing umbilical cord blood stem cells for cryopreservation according to claim 6, wherein, A second spring damper (305) is provided on the outside of the clamping plate (303), and the second spring damper (305) is fixed on the inner wall of the mesh cylinder (302).

8. The umbilical cord blood sample containing umbilical cord blood stem cells for cryopreservation according to claim 7, wherein, The bottom end of the clamping plate (303) is provided with an arc-shaped outward flange (306).

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