A traditional Chinese medicine yinqiao granule for treating wind-heat cold and a preparation method thereof

Abstract

This invention discloses a traditional Chinese medicine, Yinqiao Granules, for treating wind-heat colds, prepared from the following components in parts by weight: Forsythia suspensa 12-16 parts, Lonicera japonica 10-20 parts, Codonopsis pilosula 8-12 parts, Pseudostellaria heterophylla 14-18 parts, Mentha haplocalyx 15-25 parts, Cicadae periostracum 8-12 parts, Oroxylum indicum 10-14 parts, Gardenia jasminoides 12-16 parts, Rehmannia glutinosa 12-16 parts, Nelumbo nucifera rhizome 10-20 parts, Platycladus orientalis leaf 8-12 parts, and Ophiopogon japonicus. The formula contains 10-20 parts of Dendrobium, 5-15 parts of Prunus mume, 8-12 parts of Polygonatum odoratum, 10-20 parts of Amomum villosum, 8-12 parts of Coix lacryma-jobi, 12-16 parts of chicken gizzard lining, 12-16 parts of radish seed, and 8-12 parts of dried tangerine peel. The whole formula is pungent and cool to relieve exterior syndromes, clear heat and detoxify, while clearing the lungs and relieving sore throat, replenishing qi and blood, promoting body fluid and quenching thirst, strengthening the spleen and stomach, and promoting digestion. It is effective in treating wind-heat cold with food stagnation syndrome, and its preparation method is disclosed.

Description

Technical Field

[0001] This application belongs to the field of traditional Chinese medicine technology, specifically relating to a traditional Chinese medicine, Yinqiao Granules, for treating wind-heat colds, and its preparation method. Background Technology

[0002] In Traditional Chinese Medicine (TCM), the common cold is mostly caused by external wind-evil. This wind-evil invades the body, weakening the defensive qi (wei qi), leading to a series of symptoms. TCM classifies colds into various types, such as wind-cold, wind-heat, and summer-dampness colds, each with different treatment principles and methods. Wind-heat cold, also known as wind-heat type, is caused by external wind-heat evil, which invades the lung and defensive qi, leading to disharmony of lung qi and impaired lung function. This disease mainly occurs in spring and summer, when warm weather triggers wind-heat evil. Disharmony of the lung and defensive qi, and impaired lung function, are the main pathogenesis of wind-heat cold. Whether or not this disease occurs depends on the severity of the evil and the strength of the individual's defensive qi. Those with weak constitutions are more susceptible. Clinically, it often does not present solely as wind-heat cold symptoms, frequently accompanied by food stagnation. Currently, there is no effective treatment. Summary of the Invention

[0003] In order to overcome the above-mentioned shortcomings and deficiencies of the prior art, the purpose of this application is to provide a traditional Chinese medicine Yinqiao granule for treating wind-heat cold and its preparation method.

[0004] To achieve the above objectives, in the first aspect, this application provides a traditional Chinese medicine, Yinqiao Granules, for treating wind-heat colds, prepared from the following components in parts by weight: Forsythia suspensa 12-16 parts, Lonicera japonica 10-20 parts, Codonopsis pilosula 8-12 parts, Pseudostellaria heterophylla 14-18 parts, Mentha haplocalyx 15-25 parts, Cicadae periostracum 8-12 parts, Oroxylum indicum 10-14 parts, Gardenia jasminoides 12-16 parts, Rehmannia glutinosa 12-16 parts, Nelumbo nucifera rhizome 10-20 parts, Platycladus orientalis leaf 8-12 parts, Ophiopogon japonicus 10-20 parts, Dendrobium nobile 5-15 parts, Prunus mume 8-12 parts, Polygonatum odoratum 10-20 parts, Amomum villosum 8-12 parts, Coix lacryma-jobi 10-20 parts, Gallus gallus domesticus gizzard lining 12-16 parts, Raphanus sativus seed 12-16 parts, and Citrus reticulata peel 8-12 parts.

[0005] The aforementioned Yinqiao granules, a traditional Chinese medicine for treating wind-heat colds, are prepared from the following components in parts by weight: Forsythia suspensa 14 parts, Lonicera japonica 15 parts, Codonopsis pilosula 10 parts, Pseudostellaria heterophylla 16 parts, Mentha haplocalyx 20 parts, Cicadae periostracum 10 parts, Oroxylum indicum 12 parts, Gardenia jasminoides 14 parts, Rehmannia glutinosa 14 parts, Nelumbo nucifera rhizome 15 parts, Platycladus orientalis leaf 10 parts, Ophiopogon japonicus 15 parts, Dendrobium nobile 10 parts, Prunus mume 10 parts, Polygonatum odoratum 15 parts, Amomum villosum 10 parts, Coix lacryma-jobi 15 parts, Gallus gallus domesticus gizzard lining 14 parts, Raphanus sativus seed 14 parts, and Citrus reticulata peel 10 parts.

[0006] The aforementioned Yinqiao granules, a traditional Chinese medicine for treating wind-heat colds, are prepared from the following components in parts by weight: Forsythia suspensa 12 parts, Lonicera japonica 20 parts, Codonopsis pilosula 8 parts, Pseudostellaria heterophylla 18 parts, Mentha haplocalyx 15 parts, Cicadae periostracum 12 parts, Oroxylum indicum 10 parts, Gardenia jasminoides 16 parts, Rehmannia glutinosa 12 parts, Nelumbo nucifera rhizome 20 parts, Platycladus orientalis leaf 8 parts, Ophiopogon japonicus 20 parts, Dendrobium nobile 5 parts, Prunus mume 12 parts, Polygonatum odoratum 10 parts, Amomum villosum 12 parts, Coix lacryma-jobi 10 parts, Gallus gallus domesticus gizzard lining 16 parts, Raphanus sativus seed 12 parts, and Citrus reticulata peel 12 parts.

[0007] The aforementioned Yinqiao granules, a traditional Chinese medicine for treating wind-heat colds, are prepared from the following components in parts by weight: Forsythia suspensa 16 parts, Lonicera japonica 10 parts, Codonopsis pilosula 12 parts, Pseudostellaria heterophylla 14 parts, Mentha haplocalyx 25 parts, Cicadae periostracum 8 parts, Oroxylum indicum 14 parts, Gardenia jasminoides 12 parts, Rehmannia glutinosa 16 parts, Nelumbo nucifera rhizome 10 parts, Platycladus orientalis leaf 12 parts, Ophiopogon japonicus 10 parts, Dendrobium nobile 15 parts, Prunus mume 8 parts, Polygonatum odoratum 20 parts, Amomum villosum 8 parts, Coix lacryma-jobi 20 parts, Gallus gallus domesticus gizzard lining 12 parts, Raphanus sativus seed 16 parts, and Citrus reticulata peel 8 parts.

[0008] Secondly, this application provides a traditional Chinese medicine, Yinqiao granules, for treating wind-heat type common cold, the preparation method of which includes the following steps:

[0009] (1) Mix the Chinese medicinal herbs, mix them with water and extract them, then filter to obtain the extract and filter residue;

[0010] (2) Mix the filter residue with water and boil twice, then filter to obtain the filtrate;

[0011] (3) The extract and filtrate are mixed and concentrated under reduced pressure to obtain an extract paste, which is then dried, and excipients are added to prepare granules.

[0012] The traditional Chinese medicine Yinqiao granules for treating wind-heat colds, in step (1), the mass ratio of the Chinese medicine decoction pieces to water is 1:3-5.

[0013] The traditional Chinese medicine Yinqiao granules for treating wind-heat cold, in step (1), the extraction time is 1.5-2.5h; the extraction temperature is 55-65℃.

[0014] The traditional Chinese medicine Yinqiao granules for treating wind-heat cold, in step (2) the mass ratio of the filter residue to water is 1:5-8, the decoction time is 2.5-3.5h, in step (3) the extract is concentrated under reduced pressure to a relative density of 1.10-1.20 at 55℃, the drying temperature is 50-60℃, and the drying time is 3.5-5 hours.

[0015] The aforementioned Yinqiao Granules, a traditional Chinese medicine for treating wind-heat colds, fall under the category of wind-heat colds complicated by food stagnation.

[0016] The aforementioned Yinqiao Granules, a traditional Chinese medicine for treating wind-heat colds, are for children with wind-heat colds complicated by food stagnation.

[0017] Common cold with wind-heat syndrome and food stagnation is more common in children. Symptoms: Wind-heat syndrome, main symptoms: high fever, mild chills, red and swollen throat. Secondary symptoms: sweating or no sweating, headache, nasal congestion, thick nasal discharge, cough, irritability, thirst, red tongue, thin yellow coating, and floating and rapid pulse. Concurrent symptoms: Food stagnation, cold accompanied by abdominal distension, loss of appetite, or vomiting of sour and foul odor, foul breath, loose and foul-smelling stools or constipation, thick or yellow tongue coating, and slippery pulse.

[0018] Children are inherently of pure Yang nature, and when they contract external wind-evil, it easily penetrates deeper and transforms into heat, with heat being more prevalent than cold. Wind-cold syndromes are also prone to cold transforming into heat, or heat becoming cold and obstructing the flow of Qi. Therefore, external pathogens in children are mostly characterized by heat syndromes. Chao Yuanfang, in his *Treatise on the Causes and Symptoms of Various Diseases - Wind-Heat Syndrome*, states: "Wind-heat viruses, the wind-heat Qi first enters the lungs through the skin and hair. The lungs are the upper cover of the five internal organs, and they govern the skin and hair of the body. If the skin and pores are weak, the wind-heat Qi will first damage the skin and hair before entering the lungs. Symptoms include aversion to wind and cold, shivering, eyes feeling like they are about to pop out, and nasal discharge. After seven or eight days, slightly greenish-yellow purulent nasal discharge, the size of a bullet, will come out from the mouth and nose, which is a good sign. If it does not come out, it damages the lungs, leading to coughing and spitting purulent blood." Treatment requires pungent and cooling herbs to release the exterior, clear heat and detoxify, while simultaneously clearing the lungs and soothing the throat.

[0019] The book *Explanation of Pediatric Mysteries: Common Cold* states, "The origin of the common cold is due to deficiency of Wei Qi, failure of the Yuanfu (vital energy) to close, and frequent loosening of the membranes, allowing pathogenic winds to invade..." The *Treatise on the Causes and Symptoms of Various Diseases* by Chao Yuanfang of the Sui Dynasty points out physiological characteristics such as "unstable blood and Qi in children," "weak spleen and stomach," and "insufficient true Qi." If a child cannot regulate their diet, the spleen's inability to transform and transport nutrients can easily lead to internal stagnation, which, if left undigested, can generate internal heat. Additionally, it can be due to congenital deficiencies in children, or the transmission of fetal toxins from the mother during pregnancy. Following the principle of treating both the root cause and the symptoms, in addition to relieving the exterior symptoms, it is necessary to replenish Qi and blood and strengthen the body's resistance.

[0020] When pathogenic heat invades the body, it easily leads to internal liver wind and forced blood to flow erratically. This is especially true for children with wind-heat colds, who are prone to symptoms such as nosebleeds, requiring methods to clear heat, detoxify, cool the blood, and stop bleeding. Wind-heat colds generally present with fever, as well as discomfort such as dry mouth and tongue, thirst, yellow nasal discharge, and sore throat, which deplete body fluids and require methods to generate fluids and quench thirst.

[0021] It is evident that children's unique physiological characteristics, such as weak defensive qi, underdeveloped constitution, and insufficient spleen function, make them more susceptible to illness than adults. The lungs, acting as a protective canopy, are the first to be affected by external pathogens. Furthermore, the lungs are vulnerable due to the obstruction of external pathogens, loose muscles and weak defensive qi, resulting in poor resistance to disease. The invasion of pathogens often impairs the spleen's digestive and transformative functions, a phenomenon known as "the child's illness affecting the mother," as the spleen is the foundation of postnatal health and the center for the transformation and transportation of food and water in children. Because children cannot regulate their own diet, their spleen and stomach are easily damaged, and impaired spleen function hinders growth and development. As stated in Wu Qian's *Medical Mirror* (Qing Dynasty), "Children's irregular eating habits lead to internal stagnation, which, combined with external wind-cold invasion, results in this condition." Therefore, for wind-heat colds with food stagnation, it is necessary to strengthen the spleen and stomach and promote digestion.

[0022] In summary, this invention utilizes Forsythia suspensa and Lonicera japonica to relieve exterior syndromes, clear heat and detoxify, and disperse wind-heat, thereby dispersing the pathogenic heat in the upper burner (lung and wei qi), achieving the effect of "purely clearing and purifying the upper burner" of the lung and wei qi. Combined with Mentha haplocalyx, Cicadae periostracum, and Oroxylum indicum to clear the lungs and soothe the throat, disperse wind-heat, clear the head and eyes, and detoxify and soothe the throat, and Codonopsis pilosula and Pseudostellaria heterophylla to replenish qi and blood, serving as the principal herbs. Gardenia jasminoides, Rehmannia glutinosa, Nelumbo nucifera rhizome, and Platycladus orientalis leaves are used to purge fire and detoxify, cool the blood and stop bleeding; Ophiopogon japonicus, Dendrobium nobile, Prunus mume, and Polygonatum odoratum are used to generate fluids and quench thirst, serving as the assistant herbs; Amomum villosum, Coix lacryma-jobi, and Gallus gallus domesticus strengthen the spleen and stomach, while Raphanus sativus and Citrus reticulata promote digestion and relieve stagnation, serving as the adjuvant herbs. The entire formula is pungent and cool in nature, relieves exterior syndromes, clears heat and detoxifies, while simultaneously clearing the lungs and soothing the throat, replenishing qi and blood, generating fluids and quenching thirst, strengthening the spleen and stomach, and promoting digestion and relieving stagnation, showing significant efficacy in treating wind-heat colds with food stagnation. Detailed Implementation

[0023] The present invention will be further described below with reference to specific embodiments. It should be understood that these embodiments are for illustrative purposes only and are not intended to limit the scope of the invention. Furthermore, it should be understood that after reading the description of this invention, those skilled in the art can make various alterations or modifications to the invention, but these equivalent forms also fall within the scope defined by the appended claims.

[0024] Example 1:

[0025] Take 14g of Forsythia suspensa, 15g of Lonicera japonica, 10g of Codonopsis pilosula, 16g of Pseudostellaria heterophylla, 20g of Mentha haplocalyx, 10g of Cicadae Periostracum, 12g of Oroxylum indicum, 14g of Gardenia jasminoides, 14g of Rehmannia glutinosa, 15g of Nelumbo nucifera rhizome, 10g of Platycladus orientalis leaf, 15g of Ophiopogon japonicus, 10g of Dendrobium nobile, 10g of Prunus mume, 15g of Polygonatum odoratum, 10g of Amomum villosum, 15g of Coix lacryma-jobi, 14g of chicken gizzard lining, 14g of Raphanus sativus seed, and 10g of Citrus reticulata peel. The preparation method includes the following steps:

[0026] (1) Mix the Chinese medicinal herbs and extract them with water. The mass ratio of Chinese medicinal herbs to water is 1:4, and the extraction time is 2. The extraction temperature is 60℃. Filter to obtain the extract and filter residue.

[0027] (2) The filter residue is mixed with water and boiled twice, and then filtered to obtain filtrate. The mass ratio of filter residue to water is 1:6, and the boiling time is 3 hours.

[0028] (3) The extract and filtrate are mixed and concentrated under reduced pressure to obtain an extract, which is then dried. In step (3), the extract is concentrated under reduced pressure to a relative density of 1.15 at 55°C. The drying temperature is 55°C and the drying time is 4 hours. Dextrin is added to prepare granules.

[0029] Example 2:

[0030] Take 12g of Forsythia suspensa, 20g of Lonicera japonica, 8g of Codonopsis pilosula, 18g of Pseudostellaria heterophylla, 15g of Mentha haplocalyx, 12g of Cicadae periostracum, 10g of Oroxylum indicum, 16g of Gardenia jasminoides, 12g of Rehmannia glutinosa, 20g of Nelumbo nucifera rhizome, 8g of Platycladus orientalis leaf, 20g of Ophiopogon japonicus, 5g of Dendrobium nobile, 12g of Prunus mume, 10g of Polygonatum odoratum, 12g of Amomum villosum, 10g of Coix lacryma-jobi, 16g of chicken gizzard lining, 12g of Raphanus sativus seed, and 12g of Citrus reticulata peel. The preparation method includes the following steps:

[0031] (1) Mix the Chinese medicinal herbs and extract them with water. The mass ratio of the Chinese medicinal herbs to water is 1:3, and the extraction time is 2.5h. The extraction temperature is 55℃. Filter to obtain the extract and filter residue.

[0032] (2) The filter residue is mixed with water and boiled twice, and then filtered to obtain filtrate. The mass ratio of filter residue to water is 1:8, and the boiling time is 2.5h.

[0033] (3) The extract and filtrate are mixed and concentrated under reduced pressure to obtain an extract, which is then dried. In step (3), the extract is concentrated under reduced pressure to a relative density of 1.20 at 55°C. The drying temperature is 50°C and the drying time is 5 hours. Dextrin is added to prepare granules.

[0034] Example 3:

[0035] Take 16g of Forsythia suspensa, 10g of Lonicera japonica, 12g of Codonopsis pilosula, 14g of Pseudostellaria heterophylla, 25g of Mentha haplocalyx, 8g of Cicadae periostracum, 14g of Oroxylum indicum, 12g of Gardenia jasminoides, 16g of Rehmannia glutinosa, 10g of Nelumbo nucifera rhizome, 12g of Platycladus orientalis leaf, 10g of Ophiopogon japonicus, 15g of Dendrobium nobile, 8g of Prunus mume, 20g of Polygonatum odoratum, 8g of Amomum villosum, 20g of Coix lacryma-jobi, 12g of chicken gizzard lining, 16g of Raphanus sativus seed, and 8g of Citrus reticulata peel. The preparation method includes the following steps:

[0036] (1) Mix the Chinese medicinal herbs and extract them with water. The mass ratio of the Chinese medicinal herbs to water is 1:5, and the extraction time is 1.5h. The extraction temperature is 65℃. Filter to obtain the extract and filter residue.

[0037] (2) The filter residue is mixed with water and boiled twice, and then filtered to obtain filtrate. The mass ratio of filter residue to water is 1:5, and the boiling time is 3.5h.

[0038] (3) The extract and filtrate are mixed and concentrated under reduced pressure to obtain an extract, which is then dried. In step (3), the extract is concentrated under reduced pressure to a relative density of 1.10 at 55°C. The drying temperature is 60°C and the drying time is 3.5 hours. Dextrin is added to prepare granules.

[0039] Example 4: Pharmacodynamic study of the antipyretic effect of the present invention (antipyretic effect on an endotoxin-induced fever model in rabbits)

[0040] Endotoxin preparation: Prepared to a dose of 250 ng / ml / kg before the experiment.

[0041] Rabbit selection: After the rabbits entered the laboratory, their basal rectal temperature was measured 2 days before the experiment and on the morning of the experiment. Rabbits with three basal rectal temperature values ​​between 38.0 and 39.5℃ and fluctuations within 0.3℃ each time were selected for the experiment.

[0042] Experimental Methods: Rabbits with normal body temperature were randomly divided into four groups based on their basal rectal temperature on the day of the experiment: a normal control group, a model control group, an aspirin control group, and the first group of this invention, with six rabbits in each group. The aspirin control group was administered 0.15 g / kg via gavage once, while the first group of this invention was administered 5 g of raw herb / kg via gavage once. The normal control and model control groups were administered distilled water via gavage under the same conditions. One hour after gavage, except for the normal control group, all other groups were injected with 1 ml / kg of endotoxin via the marginal ear vein to establish the model. Rectal temperatures were measured at 1 h, 2 h, 3 h, and 4 h after model establishment. The difference between the rectal temperature at different times and the basal rectal temperature was used as an indicator of body temperature change. The results were statistically analyzed using a t-test for intergroup comparisons. The results are shown in Table 1.

[0043] Table 1. Antipyretic effect of the present invention on endotoxin-induced fever model in rabbits.

[0044]

[0045] Compared with the normal control group, #P<0.05, ##P<0.01; compared with the model group, *P<0.05, **P<0.01

[0046] Table 1 shows that in the endotoxin-induced fever model in rabbits, the aspirin group and the group of Example 1 of this invention had significant antipyretic effects on rabbits at 1h, 2h and 3h after modeling, and were significantly different from the model group.

[0047] Example 5: Clinical Study

[0048] Diagnostic Criteria: Western Medicine Diagnostic Criteria: Formulated with reference to the 2002 "Guiding Principles for Clinical Research of New Traditional Chinese Medicine" and the diagnostic criteria for upper respiratory tract infection complicated with digestive dysfunction in the 7th edition of "Zhu Futang's Practical Pediatrics" edited by Hu Yamei and Jiang Zaifang: Clinical manifestations of upper respiratory tract infection are mainly local symptoms, with systemic symptoms present or not obvious. Local symptoms include runny nose, sneezing, nasal congestion, sometimes cough, sore throat, hoarseness, and tearing. Systemic symptoms include chills, fever, general malaise, headache, dizziness, and aches and pains in the limbs and lower back. Blood tests show a normal or low white blood cell count. Digestive dysfunction is a syndrome including vomiting, loss of appetite, diarrhea, constipation, abdominal distension, abdominal pain, and hematochezia. Clinically, one symptom is predominant, with other symptoms appearing interspersed.

[0049] Traditional Chinese Medicine Diagnostic Criteria: These criteria are based on the syndrome differentiation diagnostic standards for the common cold in the 2002 "Guiding Principles for Clinical Research of New Traditional Chinese Medicine" and the diagnostic points for concurrent syndromes of the common cold in "Traditional Chinese Medicine Pediatrics" edited by Wang Shouchuan. Symptoms: Common cold with wind-heat syndrome. Main symptoms: high fever, mild chills, and red, swollen throat. Secondary symptoms: sweating or no sweating, headache, nasal congestion, thick nasal discharge, cough, irritability, thirst, red tongue, thin yellow coating, and floating, rapid pulse. Concurrent symptoms: Stagnation syndrome, common cold accompanied by abdominal distension, loss of appetite, or vomiting of sour or foul-smelling substances, foul breath, loose or foul-smelling stools or constipation, thick or yellow tongue coating, and slippery pulse.

[0050] Case selection: Patients meeting the above diagnostic criteria in both traditional Chinese and Western medicine, aged 8-12 years, with a disease course of less than 72 hours and a body temperature above 37.5℃. Fifty patients were included (28 males and 22 females), aged 8-12 years. They took the granules prepared in Example 1 daily (daily prescription dosage: Forsythia 14g, Honeysuckle 15g, Codonopsis 10g, Pseudostellaria 16g, Peppermint 20g, Cicada Slough 10g, Oroxylum indicum 12g, Gardenia 14g, Rehmannia 14g, Lotus Root 15g, Platycladus orientalis Leaf 10g, Ophiopogon japonicus 15g, Dendrobium 10g, Prunus mume 10g, Polygonatum odoratum 15g, Amomum villosum 10g, Coix Seed 15g, Chicken Gizzard Membrane 14g, Radish Seed 14g, Tangerine Peel 10g), divided into three doses (morning, noon, and evening), for seven days as one course of treatment.

[0051] Efficacy assessment: Based on the "Guiding Principles for Clinical Research on Traditional Chinese Medicine (New Drugs) for the Treatment of Colds," the criteria are categorized as cured, significantly effective, improved, and ineffective. The assessment is primarily based on body temperature and the rate of temperature reduction. ① Cured: Body temperature returns to normal within 3 days of treatment, and all cold symptoms disappear. ② Significantly effective: Body temperature returns to normal within 3 days of treatment, and most cold symptoms disappear. ③ Effective: Body temperature decreases compared to before treatment within 3 days of treatment, and all major cold symptoms disappear. ④ Ineffective: Body temperature does not decrease or increases within 3 days of treatment, and the major cold symptoms do not improve.

[0052] Clinical application of this invention showed that after one course of treatment, 23 out of 50 cases were cured, 14 cases showed significant improvement, 10 cases were effective, and 3 cases were ineffective, with a total effective rate of 94%. No adverse reactions were observed during use, indicating that this invention has the effects of relieving exterior syndromes with pungent and cool properties, clearing heat and detoxifying, clearing the lungs and relieving sore throat, replenishing qi and blood, promoting body fluid production and quenching thirst, strengthening the spleen and stomach, and promoting digestion and relieving stagnation. It is effective in treating wind-heat colds with food stagnation syndrome.

[0053] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A traditional Chinese medicine, Yinqiao granules, for treating wind-heat type common cold, characterized in that, It is prepared from the following components in parts by weight: Forsythia 12-16 parts, Honeysuckle 10-20 parts, Codonopsis 8-12 parts, Pseudostellaria 14-18 parts, Peppermint 15-25 parts, Cicada slough 8-12 parts, Oroxylum indicum 10-14 parts, Gardenia 12-16 parts, Rehmannia glutinosa 12-16 parts, Nelumbo nucifera rhizome 10-20 parts, Platycladus orientalis leaf 8-12 parts, Ophiopogon japonicus 10-20 parts, Dendrobium nobile 5-15 parts, Prunus mume 8-12 parts, Polygonatum odoratum 10-20 parts, Amomum villosum 8-12 parts, Coix lacryma-jobi 10-20 parts, Chicken gizzard lining 12-16 parts, Radish seed 12-16 parts, and Tangerine peel 8-12 parts. This formula is for wind-heat colds, specifically wind-heat colds with food stagnation syndrome.

2. The Yinqiao granules, a traditional Chinese medicine for treating wind-heat type common cold as described in claim 1, are characterized in that... It is prepared from the following components in parts by weight: Forsythia 14 parts, Honeysuckle 15 parts, Codonopsis 10 parts, Pseudostellaria 16 parts, Peppermint 20 parts, Cicada slough 10 parts, Oroxylum indicum 12 parts, Gardenia 14 parts, Rehmannia glutinosa 14 parts, Lotus root node 15 parts, Platycladus orientalis leaf 10 parts, Ophiopogon japonicus 15 parts, Dendrobium nobile 10 parts, Prunus mume 10 parts, Polygonatum odoratum 15 parts, Amomum villosum 10 parts, Coix lacryma-jobi 15 parts, Chicken gizzard lining 14 parts, Radish seed 14 parts, and Tangerine peel 10 parts.

3. The Yinqiao granules, a traditional Chinese medicine for treating wind-heat type common cold as described in claim 1, are characterized in that... It is prepared from the following components in parts by weight: Forsythia 12 parts, Honeysuckle 20 parts, Codonopsis 8 parts, Pseudostellaria 18 parts, Peppermint 15 parts, Cicada slough 12 parts, Oroxylum indicum 10 parts, Gardenia 16 parts, Rehmannia glutinosa 12 parts, Lotus root node 20 parts, Platycladus orientalis leaf 8 parts, Ophiopogon japonicus 20 parts, Dendrobium nobile 5 parts, Mume 12 parts, Polygonatum odoratum 10 parts, Amomum villosum 12 parts, Coix lacryma-jobi 10 parts, Chicken gizzard lining 16 parts, Radish seed 12 parts, and Tangerine peel 12 parts.

4. The Yinqiao granules, a traditional Chinese medicine for treating wind-heat type common cold as described in claim 1, are characterized in that... It is prepared from the following components in parts by weight: Forsythia 16 parts, Honeysuckle 10 parts, Codonopsis 12 parts, Pseudostellaria 14 parts, Peppermint 25 parts, Cicada slough 8 parts, Oroxylum indicum 14 parts, Gardenia 12 parts, Rehmannia glutinosa 16 parts, Lotus root node 10 parts, Platycladus orientalis leaf 12 parts, Ophiopogon japonicus 10 parts, Dendrobium nobile 15 parts, Prunus mume 8 parts, Polygonatum odoratum 20 parts, Amomum villosum 8 parts, Coix lacryma-jobi 20 parts, Chicken gizzard lining 12 parts, Radish seed 16 parts, and Tangerine peel 8 parts.

5. The Yinqiao granules, a traditional Chinese medicine for treating wind-heat type common cold as described in claim 1, are characterized in that... The preparation method includes the following steps: (1) Mix the Chinese medicinal herbs, mix them with water and extract them, then filter to obtain the extract and filter residue; (2) Mix the filter residue with water and boil twice, then filter to obtain the filtrate; (3) The extract and filtrate are mixed and concentrated under reduced pressure to obtain an extract paste, which is then dried, and excipients are added to prepare granules.

6. The Yinqiao granules, a traditional Chinese medicine for treating wind-heat type common cold as described in claim 5, are characterized in that... The mass ratio of the Chinese herbal medicine slices to water in step (1) is 1:3-5.

7. The Yinqiao granules, a traditional Chinese medicine for treating wind-heat type common cold as described in claim 5, are characterized in that... The extraction time in step (1) is 1.5-2.5 hours; the extraction temperature is 55-65°C.

8. The Yinqiao granules, a traditional Chinese medicine for treating wind-heat type common cold as described in claim 5, are characterized in that... In step (2), the mass ratio of the filter residue to water is 1:5-8, the decoction time is 2.5-3.5h, in step (3), the extract is concentrated under reduced pressure to a relative density of 1.10-1.20 at 55℃, the drying temperature is 50-60℃, and the drying time is 3.5-5 hours.

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