Tibetan flower fragrance compound, preparation method thereof and Tibetan flower fragrance essence

Abstract

The invention relates to the technical field of flavors and fragrances, in particular to a Tibetan flower aroma compound, a preparation method thereof and Tibetan flower aroma essence, and the Tibetan flower aroma compound has the following structural formula: # imgabs0 #. The compound provided by the invention has prominent Tibetan flower fragrance and fruity fragrance, is long in fragrance retention time, has a good fragrance quality improvement effect, and has important application in the field of daily chemical flavor blending. The preparation method of the Tibetan flower aroma compound is simple in process, convenient to operate and control, high in production efficiency and beneficial to industrial production, the prepared compound is stable in quality, elegant in aroma and long in aroma retention time, the aroma quality is remarkably improved when the compound is used, and practicability is high.

Description

Technical Field

[0001] The invention relates to the technical field of flavors and fragrances, and in particular to a safflower aroma compound and a preparation method thereof and a safflower aroma essence. Background Art

[0002] Tibetan flowers are a precious spice and Chinese medicinal material with important medicinal value and unique floral fragrance. Fresh Tibetan flowers emit a sweet floral fragrance, which gradually fades with the passage of time and changes in storage conditions. Under existing conditions, Tibetan flowers have low yields, and harvesting is time-consuming and laborious, which limits their use in the field of flavors and fragrances. Therefore, it is of great social significance and economic value to develop a Tibetan flower aroma compound with Tibetan flower fragrance, elegant fragrance, and long lasting fragrance. Summary of the invention

[0003] In order to overcome the shortcomings and deficiencies in the prior art, the purpose of the present invention is to provide a compound with a saffron aroma and a fruity aroma, which has an elegant aroma and a long lasting fragrance and is of important use in the field of daily chemical perfumery.

[0004] Another object of the present invention is to provide a method for preparing a saffron aroma compound, which is simple and efficient, easy to operate and control, has high product quality, low cost, and is conducive to industrial production. At the same time, the prepared compound exhibits a saffron aroma, has a distinct aroma, a high molecular weight, and a long fragrance retention time. It has important and beneficial uses in the field of perfumery and can well meet the needs of the daily chemical perfumery field.

[0005] Another object of the present invention is to provide a saffron aroma essence, which has saffron aroma by adding saffron aroma compounds, can effectively improve the aroma quality, and has strong practicality.

[0006] The purpose of the present invention is achieved through the following technical solution: a safflower aroma compound having the following structural formula: .

[0007] The safflower aroma compound can be named as 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester.

[0008] The compound of the invention has the aroma of Tibetan flowers and a fruity fragrance, and has a long lasting fragrance time, and has important uses in the field of daily chemical perfumery.

[0009] Another object of the present invention is achieved by the following technical solution: a method for preparing a safflower aroma compound, comprising the following steps: Step 1: preparing ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate; Step 2: preparing 6-methyl-5-heptene-2-ol; Step 3: reacting the ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate prepared in step 1 with the 6-methyl-5-heptene-2-ol prepared in step 2 to prepare 1,5-dimethyl-4-hexenol 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate.

[0010] Furthermore, in the step 1, the preparation method of ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate comprises the following steps: A1. In a reaction apparatus equipped with an oil-water separator, a condenser, a thermometer and a stirrer, ethyl acetoacetate, mesityl oxide, zinc chloride and cyclohexane were added, and the mixture was stirred, heated and refluxed for dehydration reaction until no water was released. The reaction temperature was 90-100°C and the reaction time was 46-50 hours. A2, the reaction was cooled to room temperature, then hydrochloric acid aqueous solution and cyclohexane were added to the reactants in the reaction apparatus, stirred, allowed to stand for stratification, the water layer was discarded, and then washed with sodium carbonate aqueous solution and water in sequence until neutral; A3. Recover the solvent cyclohexane under normal pressure, distill the mother liquor under reduced pressure, collect the fraction with a vapor temperature of 108-112° C. under a pressure of 650 Pa, and obtain ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate.

[0011] In the present invention, the chemical reaction formula for preparing ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate is as follows: .

[0012] Furthermore, in the step A1, 360-420 parts of ethyl acetoacetate, 270-310 parts of mesityl oxide, 65-85 parts of zinc chloride and 100-130 parts of cyclohexane are added to the reaction device in parts by weight.

[0013] Furthermore, in step A2, 250-350 parts of 8-12wt% aqueous hydrochloric acid solution and 100-130 parts of cyclohexane are added to the reactants in the reaction device, by weight, stirred, allowed to stand for stratification, the water layer is discarded, and then washed with 8-12wt% aqueous sodium carbonate solution and water in turn until neutral.

[0014] Furthermore, in the step 2, the preparation method of 6-methyl-5-heptene-2-ol comprises the following steps: B1. Prepare a sodium borohydride aqueous solution containing sodium hydroxide and sodium borohydride, add 6-methyl-5-heptene-2-one and ethanol into a reaction kettle and cool to 7-13° C., then dropwise add the sodium borohydride aqueous solution within 90-150 minutes; then wash the material with salt water; B2. The organic layer obtained by separation was subjected to reduced pressure distillation, and the fraction with a vapor temperature of 80-85° C. was collected at a pressure of 2.0 kPa to obtain 6-methyl-5-heptene-2-ol.

[0015] In the present invention, the chemical reaction formula for preparing 6-methyl-5-heptene-2-ol is as follows: .

[0016] Furthermore, in the step B1, 160-200 parts of 6-methyl-5-heptene-2-one and 190-230 parts of ethanol are added to the reaction kettle by weight, and 95-105 parts of the sodium borohydride aqueous solution are added dropwise; the concentration of sodium hydroxide in the sodium borohydride aqueous solution is 0.15-0.25wt%, and the concentration of sodium borohydride is 15-20wt%.

[0017] Furthermore, in the step 3, the preparation method of 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester comprises the following steps: C1. Add 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid ethyl ester and 6-methyl-5-heptene-2-ol into a reaction device, then add PTSA, and react at 95-105°C for 7-9 hours; after the reaction is completed, wash the material with water, sodium carbonate solution and water in turn; C2. The organic phase was distilled under reduced pressure, and the fraction with a vapor phase temperature of 168-175° C. was collected at a pressure of 150 Pa to obtain 1,5-dimethyl-4-hexenol 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate.

[0018] In the present invention, the chemical reaction formula for preparing 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester is as follows:

[0019] Furthermore, in the step C1, 190-230 parts by weight of ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate and 130-150 parts by weight of 6-methyl-5-heptene-2-ol are added to a reaction device, and then 0.8-1.2 parts of PTSA are added.

[0020] Furthermore, in step C1, the concentration of the sodium carbonate solution is 4-6wt%.

[0021] Another object of the present invention is achieved by the following technical scheme: a saffron aroma essence, comprising the following raw materials in parts by weight: 18-22 parts of geraniol, 18-22 parts of vanillin, 18-22 parts of ethyl crocetin, 47-53 parts of phenylethyl alcohol, 47-53 parts of raspberry ketone, 90-110 parts of α-methylionone, 90-110 parts of β-ionone, 90-110 parts of benzyl acetate, 90-110 parts of isobutyl acetate, 90-110 parts of ethyl acetate, 90-110 parts of amyl acetate, 200-240 parts of ethanol, and 17-23 parts of 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester.

[0022] The beneficial effects of the present invention are: the compound of the present invention has a prominent saffron fragrance with a fruity aroma, a long lasting fragrance time, a good fragrance quality improvement effect, and has important uses in the field of daily chemical fragrance adjustment. The preparation method of the saffron fragrance compound is simple in process, convenient in operation and control, high in production efficiency, conducive to industrial production, and the prepared compound has stable quality, elegant fragrance, long lasting fragrance time, and significantly improves the fragrance quality when used, and has strong practicality. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 It is a gas chromatogram of the safflower aroma compounds obtained in Example 1 of the present invention. DETAILED DESCRIPTION

[0024] In order to facilitate the understanding of those skilled in the art, the following embodiments and attached Figure 1 The present invention is further described, and the contents mentioned in the implementation modes are not intended to limit the present invention.

[0025] In an embodiment of the present invention, a safflower aroma compound has the following structural formula: .

[0026] The chemical name of the safflower aroma compound is: 6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester.

[0027] In some embodiments of the present invention, a method for preparing a safflower aroma compound comprises the following steps: Step 1: preparing ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate; Step 2: preparing 6-methyl-5-heptene-2-ol; Step 3: reacting the ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate prepared in step 1 with the 6-methyl-5-heptene-2-ol prepared in step 2 to prepare 1,5-dimethyl-4-hexenol 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate.

[0028] In some embodiments of the present invention, in the step 1, the preparation method of ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate comprises the following steps: A1. In a reaction apparatus equipped with an oil-water separator, a condenser, a thermometer and a stirrer, ethyl acetoacetate, mesityl oxide, zinc chloride and cyclohexane were added, and the mixture was stirred, heated and refluxed for dehydration reaction until no water was released. The reaction temperature was 90-100°C and the reaction time was 46-50 hours. A2, the reaction was cooled to room temperature, then hydrochloric acid aqueous solution and cyclohexane were added to the reactants in the reaction apparatus, stirred, allowed to stand for stratification, the water layer was discarded, and then washed with sodium carbonate aqueous solution and water in sequence until neutral; A3. Recover the solvent cyclohexane under normal pressure, distill the mother liquor under reduced pressure, collect the fraction with a vapor temperature of 108-112° C. under a pressure of 650 Pa, and obtain ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate.

[0029] In the present invention, the chemical reaction formula for preparing ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate is as follows: .

[0030] In some embodiments of the present invention, in step A1, 360-420 parts of ethyl acetoacetate, 270-310 parts of mesityl oxide, 65-85 parts of zinc chloride and 100-130 parts of cyclohexane are added to the reaction apparatus by weight.

[0031] In some embodiments of the present invention, in step A2, 250-350 parts of 8-12wt% aqueous hydrochloric acid solution and 100-130 parts of cyclohexane are added to the reactants in the reaction device, by weight, stirred, allowed to stand for stratification, the water layer is discarded, and then washed with 8-12wt% aqueous sodium carbonate solution and water in sequence until neutral.

[0032] In some embodiments of the present invention, in step 2, the method for preparing 6-methyl-5-heptene-2-ol comprises the following steps: B1. Prepare a sodium borohydride aqueous solution containing sodium hydroxide and sodium borohydride, add 6-methyl-5-heptene-2-one and ethanol into a reaction kettle and cool to 7-13° C., then dropwise add the sodium borohydride aqueous solution within 90-150 minutes; then wash the material with salt water; B2. The organic layer obtained by separation was subjected to reduced pressure distillation, and the fraction with a vapor temperature of 80-85° C. was collected at a pressure of 2.0 kPa to obtain 6-methyl-5-heptene-2-ol.

[0033] In the present invention, the chemical reaction formula for preparing 6-methyl-5-heptene-2-ol is as follows: .

[0034] In some embodiments of the present invention, in step B1, 160-200 parts of 6-methyl-5-heptene-2-one and 190-230 parts of ethanol are added to the reaction kettle, and 95-105 parts of the above-mentioned sodium borohydride aqueous solution are added dropwise; the concentration of sodium hydroxide in the sodium borohydride aqueous solution is 0.15-0.25wt%, and the concentration of sodium borohydride is 15-20wt%.

[0035] In some embodiments of the present invention, in step 3, the method for preparing 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester comprises the following steps: C1. Add 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid ethyl ester and 6-methyl-5-heptene-2-ol into a reaction device, then add PTSA, and react at 95-105°C for 7-9 hours; after the reaction is completed, wash the material with water, sodium carbonate solution and water in turn; C2. The organic phase was distilled under reduced pressure, and the fraction with a vapor phase temperature of 168-175° C. was collected at a pressure of 150 Pa to obtain 1,5-dimethyl-4-hexenol 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate.

[0036] In the present invention, the chemical reaction formula for preparing 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester is as follows:

[0037] In some embodiments of the present invention, in step C1, 190-230 parts by weight of ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate and 130-150 parts by weight of 6-methyl-5-heptene-2-ol are added to a reaction device, and then 0.8-1.2 parts of PTSA are added.

[0038] In some embodiments of the present invention, in step C1, the concentration of the sodium carbonate solution is 4-6wt%.

[0039] In some embodiments of the present invention, a saffron aroma essence comprises the following raw materials in parts by weight: 18-22 parts of geraniol, 18-22 parts of vanillin, 18-22 parts of ethyl crocetin, 47-53 parts of phenylethyl alcohol, 47-53 parts of raspberry ketone, 90-110 parts of α-methylionone, 90-110 parts of β-ionone, 90-110 parts of benzyl acetate, 90-110 parts of isobutyl acetate, 90-110 parts of ethyl acetate, 90-110 parts of amyl acetate, 200-240 parts of ethanol, and 17-23 parts of 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester.

[0040] In a typical embodiment of the present invention, a saffron aroma essence comprises the following raw materials in parts by weight: 20 parts of geraniol, 20 parts of vanillin, 20 parts of crocetin ethyl ester, 50 parts of phenylethyl alcohol, 50 parts of raspberry ketone, 100 parts of α-methylionone, 100 parts of β-ionone, 100 parts of benzyl acetate, 100 parts of isobutyl acetate, 100 parts of ethyl acetate, 100 parts of amyl acetate, 220 parts of ethanol, and 20 parts of 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester.

[0041] Example 1 In this embodiment, a safflower aroma compound has the following structural formula: .

[0042] The safflower aroma compound can be named as 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester.

[0043] In this embodiment, the preparation method of the above-mentioned safflower aroma compound comprises the following steps: Step 1: Preparation of ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate The chemical reaction formula for the preparation of ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate is as follows:

[0044] The preparation method of ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate comprises the following steps: A1. In a 2000mL three-necked flask equipped with an oil-water separator, a condenser, a thermometer and a stirrer, 390.0g of ethyl acetoacetate, 294.0g of mesityl oxide, 75.0g of zinc chloride and 150.0mL of cyclohexane were added successively, and the mixture was stirred, heated and refluxed for dehydration reaction until no water was released, the reaction temperature was 95°C, and the reaction time was 48 hours; A2. The reaction mixture was cooled to room temperature, and then 300.0 g of 10% hydrochloric acid aqueous solution and 150.0 mL of cyclohexane were added to the reaction mixture in the bottle, stirred for 10 minutes, allowed to stand for stratification, the water layer was discarded, and then washed with 10 wt % sodium carbonate aqueous solution and clean water in turn until neutral; A3. Recover the solvent cyclohexane under normal pressure, distill the mother liquor under reduced pressure, collect the fraction with a vapor temperature of 108-112°C under a pressure of 650 Pa, and obtain 214.5 g of product with a GC content of 96.5%.

[0045] Step 2: Preparation of 6-methyl-5-heptene-2-ol The chemical reaction formula for the preparation of 6-methyl-5-heptene-2-ol is as follows:

[0046] The preparation method of the 6-methyl-5-heptene-2-ol comprises the following steps: B1. Prepare 97.8 g of an aqueous solution containing 0.2 g of sodium hydroxide and 17.6 g of sodium borohydride, add 189.0 g of 6-methyl-5-heptene-2-one and 210.0 g of ethanol into a 1000 mL reactor and cool to 10 °C, then dropwise add the above sodium borohydride aqueous solution within 2 hours; then wash the material twice with 5% brine (300 mL each time); B2. The organic layer obtained by separation was subjected to reduced pressure distillation, and the fraction with a vapor temperature of 80-85° C. was collected at a pressure of 2.0 kPa to obtain 186.5 g of 6-methyl-5-heptene-2-ol with a GC content of 98.0%.

[0047] Step 3: Preparation of 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester The chemical reaction formula for preparing the 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester is as follows:

[0048] The preparation method of 2,6,6-trimethyl-4-oxo-2-cyclohexenyl carboxylic acid 1,5-dimethyl-4-hexenol ester comprises the following steps: B1. Put 210.0 g of ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenyl carboxylate and 138.2 g of 6-methyl-5-heptene-2-ol (molar ratio is 1:1.08) into a 500 mL three-necked flask, then add 1.0 g of PTSA, and react at 100 °C for 8 h; after the reaction, wash the material with 200 mL of clean water, 200 mL of 5wt% sodium carbonate solution, and 200 mL of clean water in sequence; B2. The organic phase was then distilled under reduced pressure, and the fraction with a vapor phase temperature of 168-175° C. was collected at a pressure of 150 Pa to obtain 256.8 g of light yellow liquid, i.e., 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester, with a GC content of 96.0%.

[0049] The 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester prepared by the present invention has the following NMR spectral characteristics: 1 H NMR (400MHz, CD 3 Cl) δ 5.96(d, 1H), 5.22(m, 1H), 4.16(m, 1H), 2.98(t,1H), 2.84(d, 2H), 1.92(m, 2H), 1.75(s, 3H), 1.72(s, 3H), 1.68(s, 3H), 1.62(m,2H), 1.42(d, 3H), 1.11(s, 3H), 1.08(s, 3H); 13 C NMR (100MHz, CD 3 Cl) δ 197.5, 172.2, 152.3, 133.1, 125.6, 121.2,72.6, 58.8, 53.2, 37.2, 25.4, 24.4, 24.3, 20.3, 20.1, 19.8, 19.6, 19.4.

[0050] The mass spectrometry data are as follows: MS (ESI, m / z) 315.2 (M + Na + );Theoretical calculation data of high resolution electrospray ionization mass spectrometry is [C 18 H 28 NaO 3 ] + (M + Na + ) 315.1850, the actual measured value is 315.1855.

[0051] Example 2 The 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester prepared in Example 1 was subjected to aroma rating, fragrance retention test and fragrance base aroma test. The test results are as follows: (1) Aroma evaluation: Nine perfumers with more than five years of experience gave the following evaluations of the aroma of the compound: All nine perfumers agreed that the compound exhibited a fruity aroma in addition to the characteristic aroma of saffron.

[0052] (2) Fragrance test: Take a scent test paper, dip it in 0.1g of 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester, place the test paper on the scent rack, and have three perfumers smell it every 2 hours. When more than 2 perfumers cannot perceive the scent of the scent test paper, record the fragrance retention time. The fragrance retention test shows that the fragrance retention time of 6-methyl-8-phenyl-2-nonenoic acid ethyl ester is 220 hours.

[0053] The fragrance retention test shows that the fragrance retention time of 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester of the flower aroma is 96 hours, and the fragrance retention time of the fruity aroma is 48 hours.

[0054] (3) Fragrance base aroma test: The fragrance base formula is shown in the following table:

[0055] According to the formula in the above table, fragrance base A and fragrance base B were prepared, and 20 parts of the target product of the present invention, 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester, were added to fragrance base B. After evaluation of the fragrance base, 9 perfumers with more than 5 years of work experience made the following comments: The 9 perfumers unanimously agreed that fragrance base B had a more prominent floral aroma than fragrance base A, the Tibetan flower aroma was more prominent, the fruity aroma was sweeter, and the aroma quality was significantly improved.

[0056] The above embodiments are preferred implementation schemes of the present invention. In addition, the present invention may also be implemented in other ways. Any obvious replacement without departing from the concept of the present invention is within the protection scope of the present invention.

Claims

1. A safflower aroma compound, Features: It has the following structural formula: 。 2. A method for preparing the safflower aroma compound as claimed in claim 1, Features: The steps include: Step 1: preparing ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate; Step 2: preparing 6-methyl-5-heptene-2-ol; Step 3: reacting the ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate prepared in step 1 with the 6-methyl-5-heptene-2-ol prepared in step 2 to prepare 1,5-dimethyl-4-hexenol 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate.

3. The method for preparing the safflower aroma compound according to claim 2, Features: In the step 1, the preparation method of ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate comprises the following steps: A1. In a reaction apparatus equipped with an oil-water separator, a condenser, a thermometer and a stirrer, ethyl acetoacetate, mesityl oxide, zinc chloride and cyclohexane were added, and the mixture was stirred, heated and refluxed for dehydration reaction until no water was released. The reaction temperature was 90-100°C and the reaction time was 46-50 hours. A2, the reaction was cooled to room temperature, then hydrochloric acid aqueous solution and cyclohexane were added to the reactants in the reaction apparatus, stirred, allowed to stand for stratification, the water layer was discarded, and then washed with sodium carbonate aqueous solution and water in sequence until neutral; A3. Recover the solvent cyclohexane under normal pressure, distill the mother liquor under reduced pressure, collect the fraction with a vapor temperature of 108-112° C. under a pressure of 650 Pa, and obtain ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate.

4. The method for preparing the safflower aroma compound according to claim 3, Features: In the step A1, 360-420 parts of ethyl acetoacetate, 270-310 parts of mesityl oxide, 65-85 parts of zinc chloride and 100-130 parts of cyclohexane are added to the reaction device in parts by weight.

5. The method for preparing the safflower aroma compound according to claim 3, Features: In the step A2, 250-350 parts of 8-12 wt% aqueous hydrochloric acid solution and 100-130 parts of cyclohexane are added to the reactants in the reaction device, by weight, stirred, allowed to stand for stratification, the water layer is discarded, and then washed with 8-12 wt% aqueous sodium carbonate solution and water in sequence until neutral.

6. The method for preparing the safflower aroma compound according to claim 2, Features: In the step 2, the preparation method of 6-methyl-5-heptene-2-ol comprises the following steps: B1. Prepare a sodium borohydride aqueous solution containing sodium hydroxide and sodium borohydride, add 6-methyl-5-heptene-2-one and ethanol into a reaction kettle and cool to 7-13°C, then dropwise add the sodium borohydride aqueous solution within 90-150 minutes; then wash the material with salt water; B2. The organic layer obtained by separation was subjected to reduced pressure distillation, and the fraction with a vapor temperature of 80-85° C. was collected at a pressure of 2.0 kPa to obtain 6-methyl-5-heptene-2-ol.

7. The method for preparing the safflower aroma compound according to claim 6, Features: In the step B1, 160-200 parts of 6-methyl-5-heptene-2-one and 190-230 parts of ethanol are added to the reaction kettle, and 95-105 parts of the sodium borohydride aqueous solution are added dropwise; the concentration of sodium hydroxide in the sodium borohydride aqueous solution is 0.15-0.25wt%, and the concentration of sodium borohydride is 15-20wt%.

8. The method for preparing the safflower aroma compound according to claim 2, Features: In the step 3, the preparation method of 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid 1,5-dimethyl-4-hexenol ester comprises the following steps: C1. Add 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylic acid ethyl ester and 6-methyl-5-heptene-2-ol into a reaction device, then add PTSA, and react at 95-105°C for 7-9 hours; after the reaction is completed, wash the material with water, sodium carbonate solution and water in turn; C2. The organic phase was distilled under reduced pressure, and the fraction with a vapor phase temperature of 168-175° C. was collected at a pressure of 150 Pa to obtain 1,5-dimethyl-4-hexenol 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate.

9. The method for preparing the safflower aroma compound according to claim 8, Features: In the step C1, 190-230 parts by weight of ethyl 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate and 130-150 parts by weight of 6-methyl-5-heptene-2-ol are added to a reaction device, and then 0.8-1.2 parts of PTSA are added.

10. A Tibetan flower fragrance essence, Features: The invention comprises the following raw materials in parts by weight: 18-22 parts of geraniol, 18-22 parts of vanillin, 18-22 parts of ethyl crocetin, 47-53 parts of phenylethyl alcohol, 47-53 parts of raspberry ketone, 90-110 parts of α-methylionone, 90-110 parts of β-ionone, 90-110 parts of benzyl acetate, 90-110 parts of isobutyl acetate, 90-110 parts of ethyl acetate, 90-110 parts of amyl acetate, 200-240 parts of ethanol and 17-23 parts of 1,5-dimethyl-4-hexenol 2,6,6-trimethyl-4-oxo-2-cyclohexenylcarboxylate.

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