Composition for tonifying spleen, promoting appetite, nourishing blood and tranquilizing mind and preparation method thereof

Abstract

The invention relates to the technical field of food nutrition, and particularly discloses a spleen-tonifying, appetite-promoting, blood-nourishing and nerve-calming composition, which is prepared from the following raw materials by weight: 150 to 400 g of cattle spleen peptide, 50 to 150 g of colostrum basic protein, 2000 to 3000 g of radix pseudostellariae, 8000 to 12000 g of Chinese yam, 4000 to 6000 g of malt, and 34000 to 6000 g of endothelium corneum gigeriae galli. The composition contains a plurality of components with strictly controlled composition proportions, the substances jointly act on a human body, the spleen and stomach functions can be remarkably improved, the appetite and digestion and absorption can be improved, and the composition is beneficial to daily health care of healthy people, is also suitable for diet conditioning of sub-healthy and specific slow patient groups and has a wide market application prospect.

Description

Technical Field

[0001] The invention relates to the technical field of food nutrition, and in particular to a composition for strengthening the spleen and appetite, nourishing blood and calming the nerves, and a preparation method thereof. Background Art

[0002] With the improvement of living standards, modern people pay more and more attention to physical health and balanced nutrition. As an integral part of society, the number of people in sub-health status increases year by year. They often show symptoms such as indigestion, loss of appetite, mental fatigue, insomnia, etc. Modern medical research shows that these problems are largely related to spleen and stomach dysfunction, blood malnutrition and nervous system disorders. Therefore, the development of a health care product that can both regulate spleen and stomach function and nourish blood and calm the nerves has gradually become a market demand.

[0003] In recent years, with the development of modern science and technology, many new ingredients such as bovine spleen peptide and colostrum alkaline protein have entered people's field of vision due to their significant health benefits. For example, the prior art discloses nutritional products containing bovine spleen peptide, elderberry, HMO, colostrum alkaline protein, etc. In traditional Chinese medicine theory, the spleen and stomach are the "foundation of acquired constitution" and are the main organs for the human body to absorb nutrition and transform energy. Strengthening the spleen and appetite as well as nourishing blood and calming the nerves are commonly used methods for Chinese medicine to regulate sub-health conditions. Many herbs have been used by doctors of all dynasties to regulate the spleen and stomach and nourish blood and calm the nerves. However, how to combine traditional herbs with modern health ingredients to design products that are in line with modern people's eating habits and have the effects of strengthening the spleen and appetite, nourishing blood and calming the nerves is a problem that needs to be solved at present. Summary of the invention

[0004] The purpose of the present invention is to provide a composition and a preparation method for strengthening the spleen and appetite, nourishing blood and calming the nerves, so as to solve the problems raised in the above background technology.

[0005] To achieve the above purpose, the present invention provides the following technical scheme: a composition for strengthening the spleen, appetizing, nourishing blood and calming the nerves, the composition is made of the following raw materials by weight: 150-400g of bovine spleen peptide, 50-150g of colostrum alkaline protein, 2000-3000g of Pseudostellaria heterophylla, 8000-12000g of yam, 4000-6000g of malt, 4000-6000g of chicken gizzard lining, 14500-18300g of milk powder, 1000-2000g of lactose and 5-20g of stevioside.

[0006] The preparation method comprises the following steps: extracting the above Chinese medicine with water twice, filtering the extract, combining the filtrate, concentrating, and drying to obtain the extract powder, combining the extract powder with bovine spleen peptide, bovine spleen peptide powder, milk powder, lactose, and stevioside, mixing the mixture evenly, and packaging the mixture.

[0007] Preferably, the composition is made of the following raw materials by weight: 300g bovine spleen peptide, 80g colostrum basic protein, 2500g Pseudostellariae Radix, 10000g yam, 5000g malt, 5000g chicken gizzard lining, 16360g milk powder, 1500g lactose and 10g stevioside.

[0008] Preferably, the composition is made of the following raw materials by weight: 200g bovine spleen peptide, 60g colostrum basic protein, 2000g Pseudostellariae Radix, 8000g yam, 4000g malt, 4000g chicken gizzard lining, 15500g milk powder, 1350g lactose, and 8g stevioside.

[0009] Preferably, the composition is made of the following raw materials by weight: 375g bovine spleen peptide, 120g colostrum basic protein, 2250g Pseudostellariae Radix, 9000g yam, 4500g malt, 4500g chicken gizzard lining, 14500g milk powder, 1200g lactose, and 12g stevioside.

[0010] The composition is used as a dietary supplement for humans.

[0011] The ratio of Radix Pseudostellariae Radix, Rhizoma Dioscoreae, Fructus Malti and Gizzard Gizzard of Chicken in the above-mentioned Chinese medicine is preferably 1:4:2:2. Through a large number of experiments, the appropriate Chinese medicine combination for use with bovine spleen peptide and colostrum basic protein was determined, and the appropriate ratio was further determined. Under the above-mentioned ratio conditions, the Chinese medicine combination can produce a synergistic effect with bovine spleen peptide and colostrum basic protein, producing significantly improved effects of strengthening the spleen and appetizing, nourishing blood and calming the nerves.

[0012] Technical effects and advantages of the present invention:

[0013] The present invention provides a composition for strengthening the spleen and appetite, nourishing blood and calming the nerves, taking into account the principles of traditional Chinese medicine theory and modern nutrition science. The formula contains a variety of ingredients with strictly controlled composition ratios, including bovine spleen peptide, colostrum basic protein, Pseudostellaria baicalensis, Chinese yam, malt, and chicken gizzard lining. These substances act together on the human body, can significantly enhance the spleen and stomach function, improve appetite and digestion and absorption. In addition, the ingredients are synergistic with each other, which not only ensures the complementarity of nutrients, but also avoids mutual antagonism. The stevioside used in the present invention as a low-calorie sweetener also makes the formula more suitable for diabetic patients and consumers pursuing a healthy life. In summary, the composition is not only beneficial to the daily health care of healthy people, but also suitable for the dietary conditioning of sub-healthy people and people with specific chronic diseases, and has broad market application prospects. DETAILED DESCRIPTION

[0014] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0015] Example 1

[0016] A composition for strengthening the spleen and appetizing, nourishing blood and calming the nerves is prepared from the following raw materials by weight: 300g of bovine spleen peptide, 80g of colostrum alkaline protein, 2500g of Pseudostellaria heterophylla, 10000g of yam, 5000g of malt, 5000g of chicken gizzard lining, 16360g of milk powder, 1500g of lactose and 10g of stevioside.

[0017] The preparation method is as follows: take the above Chinese medicine and extract it twice with water, filter the extract, combine the filtrate, concentrate, and dry to obtain the extract powder, combine it with bovine spleen peptide, bovine spleen peptide powder, milk powder, lactose, and stevioside, mix them evenly, and package them to obtain the finished product.

[0018] Example 2

[0019] A composition for strengthening the spleen and appetizing, nourishing blood and calming the nerves is prepared from the following raw materials by weight: 200g of bovine spleen peptide, 60g of colostrum alkaline protein, 2000g of Pseudostellaria heterophylla, 8000g of yam, 4000g of malt, 4000g of chicken gizzard lining, 15500g of milk powder, 1350g of lactose and 8g of stevioside.

[0020] The preparation method is the same as that of Example 1.

[0021] Example 3

[0022] A composition for strengthening the spleen and appetizing, nourishing blood and calming the nerves is prepared from the following raw materials by weight: 375g of bovine spleen peptide, 120g of colostrum alkaline protein, 2250g of Pseudostellaria heterophylla, 9000g of yam, 354000g of malt, 4000g of chicken gizzard lining, 14500g of milk powder, 1200g of lactose and 12g of stevioside.

[0023] The preparation method is the same as that of Example 1.

[0024] Comparative Example 1 (without addition of bovine spleen peptide and colostrum basic protein)

[0025] A composition is prepared from the following raw materials by weight: 2500g of Pseudostellaria heterophylla, 10000g of Chinese yam, 5000g of malt, 5000g of chicken gizzard lining, 16360g of milk powder, 1500g of lactose and 10g of stevioside.

[0026] Preparation method: Take the above traditional Chinese medicine and extract it twice with water, filter the extract, combine the filtrate, concentrate, and dry to obtain the extract powder, combine it with milk powder, lactose, and stevioside, mix well, and package to obtain the finished product.

[0027] Comparative Example 2 (without adding Pseudostellaria heterophylla, Chinese yam, malt, and chicken's gizzard lining)

[0028] A composition is prepared from the following raw materials by weight: 300g of bovine spleen peptide, 80g of colostrum alkaline protein, 16360g of milk powder, 1500g of lactose and 10g of stevioside.

[0029] Preparation method: Take bovine spleen peptide and colostrum alkaline protein, combine them with milk powder, lactose and steviol glycoside, mix them evenly, and package them to obtain the finished product.

[0030] Comparative Example 3 (Change in the Ratio of Chinese Medicine)

[0031] A composition for strengthening the spleen and appetizing, nourishing blood and calming the nerves is prepared from the following raw materials by weight: 300g of bovine spleen peptide, 80g of colostrum alkaline protein, 2500g of Pseudostellaria heterophylla, 5000g of yam, 7500g of malt, 7500g of chicken gizzard lining, 16360g of milk powder, 1500g of lactose and 10g of stevioside.

[0032] The preparation method is the same as that of Example 1.

[0033] Functional experiments:

[0034] 56 healthy SD rats, half male and half female, were randomly divided into 7 groups. The normal control group was given distilled water, and the experimental group was given the composition by gavage, with a gavage volume of 10 ML / kg, for 28 consecutive days. After the last administration, the rats were fasted for 24 hours. Under ether anesthesia, the abdominal wall was incised, the pylorus was ligated, and the composition was given once through the duodenum. After suturing, 2 hours later, the incision was cut open, the cardia was ligated, the whole stomach was removed, the contents were collected, centrifuged, the supernatant was taken, the gastric juice volume was recorded, and the pepsin activity was determined by the Matt capillary method. The results are as follows.

[0035] Group Gastric juice volume (ML) Pepsin activity (U / ML) Normal control group 1.85±0.21 490.12±52.13 Example 1 Group 2.56±0.25** 556.54±61.42** Example 2 Group 2.49±0.18** 549.27±54.59** Example 3 Group 2.47±0.22** 545.61±49.34** Comparative Example 1 2.05±0.17 498.37±47.95 Comparative Example 2 2.11±0.23 510.08±45.16 Comparative Example 3 2.15±0.26 512.65±61.42

[0036] According to the above experiments, it can be seen that the composition of the present application can significantly increase the secretion of gastric juice, improve the activity of pepsin, and has the effect of strengthening the spleen and appetizing. The comparison group has a slight increase compared with the normal control, but the change is not obvious and has no significant significance. Through different comparison ratios, it can be seen that the combination of the present application has obvious synergistic effect due to the combination of traditional Chinese medicine, bovine spleen peptide, and colostrum alkaline protein. In particular, comparison example 3, which also contains traditional Chinese medicine but in an appropriate ratio, does not significantly improve the effect of strengthening the spleen and appetizing. The above results show the efficacy of the specific combination of the present application in strengthening the spleen and appetizing.

[0037] Biochemical index test experiment:

[0038] A double-blind, randomized controlled clinical trial method was adopted, and 12 volunteers with mild dyspepsia and blood deficiency insomnia symptoms were selected, 2 in each group, and the above symptoms of the volunteers did not reach the disease state. They were randomly assigned to the embodiment group and the comparative example group, and took the corresponding prescription every day for 4 consecutive weeks. The changes in symptoms and related biochemical indicators before and after taking the prescription, such as blood cell count, serum ferritin, etc., were recorded.

[0039]

[0040] The experimental results show that the example group showed a significant improvement in blood cell count after taking the composition, and the increase in serum ferritin indicated an improvement in the nutritional status of the blood, so it can be inferred that the prescription of the example has a positive effect on nourishing blood and calming the nerves. In contrast, the improvement in the indicators of the comparative example group was not obvious enough, which shows that the combination of bovine spleen peptide, colostrum basic protein and specific Chinese medicine plays a key role in the composition, and the composition containing only Chinese medicine or only bovine spleen peptide and colostrum basic protein has a significant difference in effect compared with the composition of the present application, and the comparative example 3 with a changed proportion of Chinese medicine also has no obvious effect.

[0041] The above three groups of embodiments can all be used as embodiments of the present invention, among which Embodiment 1 is the most preferred. The present invention provides a composition for strengthening the spleen and appetite, nourishing blood and calming the nerves, taking into account the principles of traditional Chinese medicine theory and modern nutritional science. The prescription contains a variety of ingredients with strictly controlled composition ratios, including bovine spleen peptide, colostrum basic protein, Pseudostellaria baicalensis, yam, malt, and chicken gizzard lining. These substances act together on the human body, can significantly enhance the spleen and stomach function, improve appetite and digestion and absorption, and significantly improve blood indicators, and play a role in nourishing blood and calming the nerves. In addition, the components are synergistic with each other, which not only ensures the complementarity of nutrients, but also avoids mutual antagonism. The stevioside used in the present invention as a low-calorie sweetener also makes the prescription more suitable for diabetic patients and consumers pursuing a healthy life. In summary, the prescription is not only beneficial to the daily health care of healthy people, but also suitable for dietary conditioning of sub-healthy people and people with specific chronic diseases, and has broad market application prospects.

[0042] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, it is still possible for those skilled in the art to modify the technical solutions described in the aforementioned embodiments or to make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A composition for strengthening the spleen and appetizing, nourishing blood and calming the nerves, characterized in that: The composition is prepared from the following raw materials by weight: 150-400g of bovine spleen peptide, 50-150g of colostrum alkaline protein, 2000-3500g of Pseudostellaria heterophylla, 8000-12000g of yam, 4000-6000g of malt, 4000-6000g of chicken gizzard lining, 14500-18300g of milk powder, 1000-2000g of lactose and 5-20g of stevioside.

2. A composition for strengthening the spleen and appetizing, nourishing blood and calming the nerves according to claim 1, characterized in that: The composition is prepared from the following raw materials by weight: 300g of bovine spleen peptide, 80g of colostrum alkaline protein, 2500g of Pseudostellaria heterophylla, 10000g of yam, 5000g of malt, 5000g of chicken gizzard lining, 16360g of milk powder, 1500g of lactose and 10g of stevioside.

3. The composition for strengthening the spleen and appetizing, nourishing blood and calming the nerves according to claim 1, characterized in that: The composition is prepared from the following raw materials by weight: 200g of bovine spleen peptide, 60g of colostrum alkaline protein, 2000g of Pseudostellaria heterophylla, 8000g of yam, 4000g of malt, 4000g of chicken gizzard lining, 15500g of milk powder, 1350g of lactose and 8g of stevioside.

4. The composition for strengthening the spleen and appetizing, nourishing blood and calming the nerves according to claim 1, characterized in that: The composition is prepared from the following raw materials by weight: 375g of bovine spleen peptide, 120g of colostrum alkaline protein, 2250g of Pseudostellaria heterophylla, 9000g of yam, 4000g of malt, 4000g of chicken gizzard lining, 14500g of milk powder, 1200g of lactose and 12g of stevioside.

5. The composition for strengthening the spleen and appetizing, nourishing blood and calming the nerves according to claim 1, characterized in that: The ratio of Prince ginseng, yam, malt and chicken's gizzard lining is 1:4:2:

2.

6. The composition for strengthening the spleen and appetizing, nourishing blood and calming the nerves according to claim 1, characterized in that: The composition is used as a dietary conditioner for humans.

7. A method for preparing the composition for strengthening the spleen and appetizing, nourishing blood and calming the nerves as claimed in any one of claims 1 to 6, characterized in that: The preparation steps are as follows: The above Chinese medicine is extracted with water twice, the extract is filtered, the filtrate is combined, concentrated, and dried to obtain the extract powder, which is combined with bovine spleen peptide, bovine spleen peptide powder, milk powder, lactose, and stevioside, mixed evenly, and packaged.

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