Ultrasonic endoscope biopsy instrument

Abstract

The invention relates to the technical field of medical instruments, in particular to an ultrasonic endoscope biopsy instrument which comprises a handle mechanism, a needle tube, a needle core and a Luer seat. The needle tube is communicated with the Luer seat, a connecting cap is fixedly arranged at one end of the needle core, the connecting cap is movably matched with the Luer seat, and the needle core penetrates through the Luer seat and an inner cavity of the needle tube; an opening communicated with the outside is formed in the end, away from the Luer base, of the needle tube, a brush section is arranged at the end of the needle core, and a plurality of cell brushes are arranged along the brush section. In order to solve the technical problem that an existing ultrasonic biopsy sampling method has defects, when the ultrasonic biopsy sampling device is used, lesion tissue can be punctured through a needle tube to develop an activity channel for a needle core in the lesion tissue, and then the lesion tissue can be repeatedly rubbed by a cell brush in a manner of pushing and pulling a connecting cap, so that the lesion tissue can be conveniently sampled. More tissue fluid exudes from the lesion tissue or more tissue structures fall off, and the cell brush can be used for well collecting and sampling, so that enough lesion samples are collected to facilitate pathological analysis.

Description

Technical Field

[0001] The present invention relates to the technical field of medical instruments, and in particular to an ultrasonic endoscopic biopsy instrument. Background Art

[0002] Endoscopic ultrasound biopsy is a technique that uses an ultrasound puncture needle to penetrate the gastrointestinal wall during ultrasound endoscopy. The conventional operation is to push a thin needle into the lesion to obtain a tissue extract for pathological analysis and biopsy.

[0003] Different diseased tissues in different pathological conditions have different structural states. The existing ultrasonic puncture technology can generally deal with diseased tissues with large amounts of tissue fluid exudation and loose structures, so tissue samples can be collected more conveniently. However, some diseased tissues do not have a large amount of exudate, and the overall structure is relatively compact. After puncture, the puncture needle can only form local holes, which cannot further promote the exudation of tissue fluid or the shedding of diseased tissue. As a result, the existing biopsy methods are almost unable to collect tissue samples, and it is difficult to obtain sufficient sample volume to meet the needs of pathological analysis. Summary of the invention

[0004] In response to the technical problem of defects in existing ultrasonic biopsy sampling methods, the present invention provides an ultrasonic endoscopic biopsy instrument. When in use, the diseased tissue is first punctured through a needle tube so that the needle core opens an active channel in the diseased tissue. Then, the connecting cap can be pushed and pulled to allow the cell brush to repeatedly rub the diseased tissue, causing the diseased tissue to exude more tissue fluid or drop more tissue structures. The cell brush can also collect samples well, thereby collecting sufficient disease samples for pathological analysis.

[0005] The technical solution provided by the present invention is: an ultrasonic endoscopic biopsy instrument, comprising a handle mechanism, a needle tube, a needle core and a Luer seat; the Luer seat is detachably arranged at one end of the handle mechanism, the needle tube is connected to the Luer seat and / or the handle mechanism, the other end of the needle tube extends from the other end of the handle mechanism to the outside, the interior of the needle tube is hollow, and the needle tube is connected to the Luer seat; a connecting cap is fixedly arranged at one end of the needle core, the connecting cap is sleeved on the outside of the Luer seat and movably cooperates with the Luer seat, and the needle core passes through the inner cavity of the Luer seat and the needle tube; an opening communicating with the outside is arranged at the end of the needle tube away from the Luer seat, a brush section is arranged at the end of the needle core, a plurality of bundles of cell brushes are arranged along the brush section, and the length of the needle core is greater than the length of the needle tube so that the brush section can extend out of the needle tube through the opening.

[0006] Optionally, the handle mechanism includes an intermediate rod, which includes an adjacent first segment and a second segment; a first sliding sleeve is sleeved on the outer side of the first segment, the Luer seat is arranged at one end of the first sliding sleeve, and a first locking piece is arranged between the first sliding sleeve and the first segment; a second sliding sleeve is sleeved on the outer side of the second segment, an outer sheath is fixedly arranged on the end of the second segment, a lead-out sheath is fixedly arranged on the end of the second sliding sleeve, the lead-out sheath is sleeved on the outer side of the outer sheath, the outer sheath is sleeved on the outer side of the needle tube, and a second locking piece is arranged between the second sliding sleeve and the second segment.

[0007] Optionally, at least one of the first segment, the second segment and the Luer seat is provided with scale markings.

[0008] Optionally, the Luer seat is snap-connected to the handle mechanism.

[0009] Optionally, it also includes a protective sleeve, one end of which is fixedly provided with an assembly end block, the assembly end block is restricted in the handle mechanism by the Luer seat, the needle tube passes through the assembly end block so that the protective sleeve is sleeved on the outside of the needle tube; a snap-fitting cavity is provided in the assembly end block, an elastic ring is provided at the end of the snap-fitting cavity away from the Luer seat, a boss is fixedly provided on the needle tube, the snap-fitting cavity is used to accommodate the boss, and when the boss is located in the snap-fitting cavity, the elastic ring is used to limit the boss from moving in the direction away from the Luer seat; wherein the distance between the boss and the needle tip of the needle tube is less than or equal to the length of the protective sleeve.

[0010] Optionally, the cell brushes adjacent to each other front to back along the length direction of the brush segment are aligned or staggered.

[0011] Optionally, there is a spacing a between the cell brushes that can overlap after falling down along the axial direction of the needle core, and the spacing a is greater than half the length of a single bundle of the cell brushes and less than the length of a single bundle of the cell brushes.

[0012] Optionally, the diameter of the brush segment is smaller than the diameter of the needle core.

[0013] Optionally, a plurality of grooves are provided on the brush segment, and when the cell brush falls over, the grooves are used to accommodate the fallen cell brushes adjacent thereto.

[0014] Optionally, the length of the cell brush gradually decreases from the end of the needle core toward the connecting cap.

[0015] Optionally, the length of the cell brush gradually decreases from both ends of the brush segment to the middle.

[0016] Optionally, a scraping portion is provided on the brush segment and / or on the needle core near the brush segment.

[0017] Optionally, the end of the needle core is provided with a spike end.

[0018] Optionally, the cell brush is made of polymer material.

[0019] The technical solution provided by the present invention has the following beneficial effects compared with the prior art: in view of the technical problems of defects in the existing ultrasonic biopsy sampling methods, the present invention can first puncture the diseased tissue through the needle tube when used, so that the needle core can open up an active channel in the diseased tissue, and then the cell brush can repeatedly rub the diseased tissue by pushing and pulling the connecting cap, so that the diseased tissue exudes more tissue fluid or drops more tissue structures, and the cell brush can collect samples well, thereby collecting sufficient disease samples for pathological analysis. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 This is one of the implementations of the ultrasonic endoscopic biopsy instrument structure proposed in the embodiment of the present invention.

[0021] Figure 2 for Figure 1 Front view of the illustrated embodiment.

[0022] Figure 3 for Figure 2 A magnified schematic diagram of the circled area at the tip of the ultrasound endoscopic biopsy instrument.

[0023] Figure 4 for Figure 1 Cross-sectional view of the illustrated embodiment.

[0024] Figure 5 for Figure 4 A partial enlargement of the cross-sectional view.

[0025] Figure 6 This is the second implementation of the ultrasonic endoscopic biopsy instrument structure proposed in the embodiment of the present invention.

[0026] Figure 7 This is a schematic diagram of the structure of the needle core proposed in an embodiment of the present invention.

[0027] Figure 8 This is one of the structural schematic diagrams of the brush segment proposed in the embodiment of the present invention.

[0028] Fig. 9 This is the second structural schematic diagram of the brush segment proposed in the embodiment of the present invention.

[0029] Fig.10 This is the third structural schematic diagram of the brush segment proposed in the embodiment of the present invention.

[0030] Fig.11 This is the fourth structural schematic diagram of the brush segment proposed in the embodiment of the present invention.

[0031] Fig.12 This is the fifth structural schematic diagram of the brush segment proposed in the embodiment of the present invention.

[0032] Fig.13 This is a schematic diagram of the cell brush lodging proposed in an embodiment of the present invention.

[0033] Fig.14 The embodiment of the present invention is proposed

[0034] Fig.15 Schematic diagram of the extraction work of the ultrasound endoscopic biopsy instrument structure. DETAILED DESCRIPTION

[0035] In order to further understand the content of the present invention, the present invention is described in detail in conjunction with the accompanying drawings and embodiments.

[0036] The present application is further described in detail below in conjunction with the accompanying drawings and embodiments. It is understood that the specific embodiments described herein are only used to explain the relevant inventions, rather than to limit the invention. It should also be noted that, for the convenience of description, only the parts related to the invention are shown in the accompanying drawings. The words "first", "second", etc. described in the present invention are set for the convenience of describing the technical solution of the present invention, and have no specific limiting effect. They are all general references and do not constitute a limiting effect on the technical solution of the present invention. It should be noted that, in the absence of conflict, the embodiments in the present application and the features in the embodiments can be combined with each other. In the description of the present invention, it should be noted that the orientation or position relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inside", "outside", etc. is based on the orientation or position relationship shown in the accompanying drawings, which is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation of the present invention. In addition, the terms "first", "second", and "third" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance. Unless otherwise clearly specified and limited, the terms "installed", "connected" and "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, or it can be a connection between the insides of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances. Multiple technical solutions in the same embodiment, and multiple technical solutions in different embodiments, can be arranged and combined to form new technical solutions without contradictions or conflicts, all of which are within the scope of protection required by the present invention.

[0037] Combined with Figure 1 To Attachment Fig.15 This embodiment proposes an ultrasonic endoscopic biopsy instrument, including a handle mechanism 1, a needle tube 2, a needle core 3 and a Luer seat 4. The Luer seat 4 is detachably arranged at one end of the handle mechanism 1, the needle tube 2 is connected to the Luer seat 4 and / or the device price 1, the other end of the needle tube 2 extends from the other end of the handle mechanism 1 to the outside, the needle tube 2 is hollow inside, and the needle tube 2 is connected to the Luer seat 4. A connecting cap 5 is fixedly arranged at one end of the needle core 3, the connecting cap 5 is sleeved on the outside of the Luer seat 4, and is movably matched with the Luer seat 4, and the needle core 3 passes through the inner cavity of the Luer seat 4 and the needle tube 2. An opening communicating with the outside is arranged at one end of the needle tube 2 away from the Luer seat 4, a brush section 30 is arranged at the end of the needle core 3, and a plurality of bundles of cell brushes 6 are arranged along the brush section 30, and the length of the needle core 3 is greater than the length of the needle tube 2, so that the brush section 30 extends out of the needle tube 2 through the opening.

[0038] The operation principle of the ultrasonic endoscopic biopsy instrument of this embodiment is as follows: first, insert the needle tube 2 into the forceps channel of the ultrasonic endoscope, and pierce the needle tip of the needle tube 2 into the diseased tissue according to the imaging of the ultrasonic endoscope. If the diseased tissue structure is relatively loose and there is a lot of tissue fluid exuded after puncture, the connecting cap 5 can be pushed and pulled several times, and the cell brush 6 at the end of the needle core 3 can be used to brush and collect the tissue fluid or tissue structure.

[0039] If the diseased tissue does not have a large amount of exudate and the overall structure is relatively tight, the connecting cap 5 can be pushed and pulled repeatedly so that the cell brush 6 repeatedly rubs the diseased tissue, causing the diseased tissue to be damaged by friction, thereby causing more tissue structures to fall off or more tissue fluid to seep out. While the cell brush 6 repeatedly rubs the diseased tissue, a large amount of detached tissue structures and tissue fluid will also adhere to the cell brush 6.

[0040] After the cell brush 6 has brushed enough diseased tissue samples, the ultrasonic endoscopic biopsy device of this embodiment has two ways to obtain tissue samples: one way is to directly remove the needle core 3, that is, by directly pulling the connecting cap 5, the needle core 3 is directly extracted from the ultrasonic biopsy device. At this time, the diseased tissue remaining on the cell brush 6 will be removed together with the needle core 3.

[0041] Another method is to use a negative pressure device for suction, for example, Fig.15 In the embodiment shown, a two-way Luer seat 4 is used. After the needle core 3 is removed, the Luer seat 4 can be directly connected to a negative pressure device such as a syringe to extract the diseased tissue. Figure 6In the embodiment shown, a three-way Luer seat 4 is used. In this case, the needle core 3 does not need to be removed, and the syringe can be directly connected to the additional connecting port of the Luer seat 4 to achieve suction. When using the three-way Luer seat 4, the needle core 3 can be repeatedly pushed and pulled to continue scraping the diseased tissue, thereby continuously generating new detached diseased tissue for suction. The needle tube 2 is connected to the Luer seat 4 and / or the handle mechanism, which means that the connection between the needle tube 2 and the Luer seat 4 can be that the needle tube 2 is directly drawn out from the Luer seat 4 (that is, the needle tube 2 is directly connected to the Luer seat 4); or, the needle tube 2 can also be connected to the Luer seat 4 through a cavity or pipeline inside the handle mechanism 1.

[0042] Combined with the above-mentioned operation mode, it can be known that the cell brush 6 in this embodiment can be taken out separately with the needle core 3, which greatly increases the convenience of surgical operation and can flexibly cope with different sampling scenarios. If the same patient needs to take samples multiple times at different lesion locations or one sampling cannot meet the sampling requirements, the needle tube 2 (which can also be understood as the outer sheath tube 14 of the instrument, or the endoscope forceps channel, or other instrument channels that enter the human body) can be replaced by the needle core 3 without withdrawing from the human body, so that repeated sampling can be achieved, which greatly saves sampling time.

[0043] Similarly, since the Luer seat 4 is detachably disposed at one end of the handle mechanism 1, and the needle tube 2 is connected to the Luer seat 4, the needle tube 2 and the needle core 3 can be taken out together by directly removing the Luer seat 4, and a new needle tube 2 and needle core 3 can be replaced on the Luer seat 4, and then reinstalled on the handle mechanism 1 to achieve multiple sampling similar to the above-mentioned situation.

[0044] In this embodiment, the cell brush 6 can be made of polymer materials including but not limited to nylon, polyester, silicone, etc. According to actual operation experience, another advantage of setting the cell brush 6 at the end of the needle core 3 in this embodiment is that since the ultrasonic biopsy technology uses an ultrasonic endoscope, based on its working principle, the imaging clarity of small objects is not very high. In this embodiment, by setting the cell brush 6 at the end of the needle core 3, the volume of the end of the needle core 3 is increased, that is, the reflection area of ​​the end of the needle core 3 is expanded, making the observability of the end of the needle core 3 more excellent, thereby improving the sampling accuracy.

[0045] In some embodiments, the handle mechanism 1 can be improved to enhance the maneuverability of the ultrasonic endoscopic biopsy instrument. For example, the handle mechanism 1 can be designed as follows: Figure 2 and attached Figure 4The handle mechanism 1 includes an intermediate rod 10, and the intermediate rod 10 includes an adjacent first segment 101 and a second segment 102; a first sliding sleeve rod 11 is sleeved on the outer side of the first segment 101, and the Luer seat 4 is arranged at one end of the first sliding sleeve rod 11, and a first locking member 13 is arranged between the first sliding sleeve rod 11 and the first segment 101; a second sliding sleeve rod 12 is sleeved on the outer side of the second segment 102, an outer sheath tube 14 is fixedly arranged at the end of the second segment 102, and a lead-out sheath 15 is fixedly arranged at the end of the second sliding sleeve rod 12, the lead-out sheath 15 is sleeved on the outer side of the outer sheath tube 14, and the outer sheath tube 14 is sleeved on the outer side of the needle tube 2, and a second locking member 16 is arranged between the second sliding sleeve rod 12 and the second segment 102.

[0046] In this embodiment, the outer sheath 14 is provided to prevent the needle tube 2 and the needle core 3 from damaging the clamp channel during the insertion of the needle tube 2 and the needle core 3 into the clamp channel of the ultrasonic endoscope. The handle mechanism 1 can achieve the following functions: (1) adjusting the extension length of the outer sheath 14; (2) adjusting the extension length of the needle tube 2.

[0047] Regarding the adjustment of the extended length of the outer sheath 14, its working principle is: taking the middle rod 10 as a static reference, the outer sheath 14 will not move relative to the middle rod 10 (i.e., the second segment 102), while the second sliding sleeve rod 12 can slide relative to the outer sheath 14, and the sliding of the second sliding sleeve rod 12 will drive the movement of the lead-out sheath 15, thereby realizing the movement of the outer sheath 14 relative to the lead-out sheath 15, thereby, the length of the outer sheath 14 exposed outside the handle mechanism 1 is adjusted.

[0048] When the position adjustment of the second sliding sleeve 12 is completed, the second locking member 16 can lock the position of the second sliding sleeve 12, thereby preventing the second sliding sleeve 12 from moving at will. Figure 4 As shown, the second locking member 16 can be a locking screw. The locking screw is rotated so that the end of the locking screw abuts against the outer wall of the middle rod 10, which can play a limiting role.

[0049] In this embodiment, the lead-out sheath 15 is also provided to extend the contact area of ​​the second sliding sheath with respect to the outer sheath 14 to prevent the outer sheath 14 from being excessively bent, thereby causing stress concentration and damage.

[0050] Regarding the adjustment of the extension length of the needle tube 2, its working principle is as follows: taking the middle rod 10 as a stationary reference, the Luer seat 4 is arranged on the first sliding sleeve rod 11, so when the first sliding sleeve rod 11 slides relative to the middle rod 10 (i.e., the first section 101), the positional relationship of the needle tube 2 relative to the middle rod 10 is actually changed, that is, the length of the needle tube 2 exposed to the outside of the handle mechanism 1 is thereby changed.

[0051] Similar to the aforementioned second sliding sleeve 12, when the position adjustment of the first sliding sleeve 11 is completed, the first locking member 13 can lock the position of the first sliding sleeve 11, thereby preventing the first sliding sleeve 11 from moving at will. Figure 2 and attached Figure 4 As shown, the first locking member 13 can be a locking screw. By rotating the locking screw, the end of the locking screw abuts against the outer wall of the middle rod 10, which can play a limiting role.

[0052] Due to the position adjustment of the outer sheath 14, the needle tube 2 and the needle core 3, in order to accurately position, in a further embodiment, scale marks can be set on the first segment 101, the second segment 102 and the Luer seat 4 to determine their respective movement positions.

[0053] The Luer seat 4 and the handle mechanism 1 in this embodiment can be detached, preferably in the form of a snap connection. The specific snap connection setting form is not limited, and the attachment Figure 5 As shown in the figure as an example, a buckle can be provided on the Luer seat 4, and a step can be provided on the handle mechanism 1, and the buckle is engaged with the step, thereby realizing a buckle connection between the Luer seat 4 and the handle mechanism 1.

[0054] It can be seen from the above embodiments that the needle tube 2 can be pulled out, but since the needle tube 2 is very long, the needle tip will swing randomly when the needle tube 2 is pulled out, which may cause damage to medical staff or patients. In order to avoid this problem, in a preferred embodiment, as shown in the attached Figure 5 , Attachment Figure 7 and attached Fig.14 As shown, the ultrasonic endoscopic biopsy instrument is also provided with a protective sleeve 70, one end of which is fixedly provided with an assembly end block 71, which is limited in the handle mechanism 1 through the Luer seat 4, and the needle tube 2 passes through the assembly end block 71 so that the protective sleeve 70 is sleeved on the outside of the needle tube 2. A clamping cavity 710 is provided in the assembly end block 71, and an elastic ring 73 is provided at one end of the clamping cavity 710 away from the Luer seat 4, and a boss 31 is fixedly provided on the needle tube 2, and the clamping cavity 710 is used to accommodate the boss 31. When the boss 31 is located in the clamping cavity 710, the elastic ring 73 is used to limit the boss 31 from moving in the direction away from the Luer seat 4.

[0055] In this embodiment, when the Luer seat 4 is removed, the assembly end block 71 loses its limit position, and as the needle tube 2 is gradually pulled out of the ultrasonic endoscopic biopsy instrument, the boss 31 on the needle tube 2 will be embedded in the assembly cavity, and the needle tube 2, the assembly end block 71 and the protective sleeve 70 can be pulled out together. Due to the setting of the elastic ring 73, the boss 31 embedded in the assembly cavity will not be separated from the assembly cavity, that is, the elastic ring 73 limits the movement of the boss 31 away from the Luer seat 4, so that even after the needle tube 2 is pulled out, the protective sleeve 70 will not move freely relative to the needle tube 2. Since the distance between the boss 31 and the needle tip of the needle tube 2 is less than or equal to the length of the protective sleeve 70, it is ensured that the needle tube 2 (especially the needle tip part) is always located in the protective sleeve 70, that is, after the needle tube 2 is pulled out of the ultrasonic endoscopic biopsy instrument, the needle tip will not be exposed to the outside, avoiding the harm that may be caused by the arbitrary swing of the needle tube 2.

[0056] In this embodiment, the layout of the cell brushes 6 can be in any form, generally arranged in an orderly manner along the brush section 30, or can be arranged in a staggered manner, as shown in the attached Figure 8 To Attachment Fig.12 The figure shows a layout of the cell brush 6. There is a certain degree of staggering between the adjacent cell brushes 6 along the length direction of the brush section 30. This can to a certain extent prevent the cell brushes 6 from squeezing each other when they are retracted into the needle tube 2, thereby causing the collected tissue sample to be squeezed out of the needle tube 2.

[0057] According to practical operation experience, even if the front and rear adjacent cell brushes 6 are arranged in a staggered manner, some of the cell brushes 6 may still squeeze each other when the needle tube 2 is retracted, thereby causing the collected tissue sample to be squeezed out. Therefore, in order to retain the tissue sample on the cell brush as much as possible, in a preferred embodiment, as shown in the attached Figure 7 As shown, there is a spacing a between the cell brushes 6 that can overlap after falling down along the axial direction of the needle core 3, and the spacing a is greater than half the length of a single cluster of cell brushes 6, and less than the length of a single cluster of cell brushes 6. Therefore, when the cell brushes 6 are retracted into the needle tube 2, they will present a certain degree of overlap, but the degree of mutual squeezing is smaller, and proper overlap can better retain tissue samples. In addition, since this overlap state is not completely overlapped, the occupied volume is smaller, and it can also ensure that there is enough space in the needle tube 2 to accommodate cell tissue.

[0058] In another embodiment, as shown in the attached Figure 8 As shown, the diameter of the brush segment 30 is smaller than the diameter of the needle core 3, that is, the needle core 3 adopts a variable diameter design. In this embodiment, when the brush segment 30 is retracted into the needle tube 2, a relatively larger space will be formed between the brush segment 30 and the needle tube 2, making it easier to collect and sample cell tissue, greatly reducing the possibility of cell tissue falling off from the needle tube 2.

[0059] In other embodiments, as shown in the attached Fig. 9 As shown, a plurality of grooves 32 are provided on the brush section 30. When the cell brush 6 falls down, the grooves 32 are used to accommodate the adjacent fallen cell brushes 6. In this embodiment, the grooves 32 can be of any shape. The grooves 32 are preferably provided between the spaced cell brushes 6. When the bristles are inside the needle tube 2, they will naturally fall down in the grooves 32. That is, the grooves 32 play a role in collecting sampled tissues. On the one hand, a larger sample volume can be obtained. On the other hand, it can also ensure that the cell tissues are not easy to fall off from the needle tube 2 during the sampling process.

[0060] Furthermore, there are other improved implementations to prevent the tissue sample from falling off when the cell brush 6 completes sampling and retracts into the needle tube 2. Fig.10 As shown, the length of the cell brush 6 gradually decreases from the end of the needle core 3 to the connecting cap 5. This arrangement ensures that when the cell brush 6 is retracted into the needle tube 2, the cell tissue can be blocked by the cell brush 6 with a larger front end, and is less likely to fall off from the needle tube 2.

[0061] In addition, in another similar embodiment, as shown in the attached Fig.11 As shown, the length of the cell brush 6 gradually decreases from the two ends of the brush section 30 to the middle. This form can make the friction sampling effect better due to the presence of a longer cell brush 6, and at the same time, a holding space can be formed in the middle of the brush section 30. When the cell brush 6 away from the end of the needle core 3 is retracted into the needle tube 2, this part of the brush will first fall down, and fall down between the cell brushes 6 in the middle of the brush section 30 with a shorter length. Since the cell brush 6 in the middle of the brush section 30 is shorter, it can play a role in storing samples. And similar to the aforementioned embodiment, the cell brush 6 near the end of the needle core 3 is relatively longer, which can ensure that when the cell brush 6 is retracted into the needle tube 2, the cell tissue can be blocked by the larger cell brush 6 at the front end, and it is less likely to fall off from the needle tube 2.

[0062] In combination with the above-mentioned embodiments, it can be known that the brush in this embodiment is used to form friction on the diseased tissue so as to make it shed more tissue structure. However, since some diseased tissues are too small or dense, it is still not possible to scrape enough tissue structure by relying on the brush. Therefore, in an improved embodiment, as shown in the attached Fig.12 As shown, a scraping portion 33 is provided on the brush segment 30 and / or on the needle core 3 near the brush segment 30 .

[0063] By setting the scraping part 33, when the needle core 3 moves, the scraping part 33 at the end thereof and the cell brush 6 will repeatedly scrape the diseased tissue, so that the dense tissue surface layer is gradually peeled off and a large amount of tissue fluid is caused to seep out.

[0064] The scraping portion 33 may be as shown in the attached Fig.12 As shown, it is a rough frosted surface on the needle core 3; or it is composed of a number of raised burrs arranged on the needle core 3, so as to easily destroy the diseased tissue and separate the cell tissue.

[0065] Furthermore, the scraping portion 33 is preferably disposed in the area of ​​the brush section 30 close to the end of the needle core 3, so that the diseased tissue can be scraped before the cell brush 6 touches the diseased tissue, thereby achieving the effect of scraping first and then collecting.

[0066] Alternatively, in another embodiment, the scraping portion 33 is disposed between the cell brushes 6, so that the diseased tissue can be scraped while the cell brushes 6 are in contact with the diseased tissue. It should be noted that although the needle tube 2 has been inserted into the diseased tissue, the diseased tissue is relatively compact and dense, and the cell brushes 6 are still in a prostrate state at the beginning, so the scraping portion 33 located between the cell brushes 6 can still contact the diseased tissue and rub and damage the diseased tissue. When the damage reaches a certain degree, the cell brush 6 can contact the diseased tissue together with the scraping portion 33, thereby achieving effective sampling of compact diseased tissue.

[0067] In addition, although the needle tube 2 has been used to pierce the diseased tissue during sampling, the needle core 3 still needs to move inside the diseased tissue, so the needle core 3 also needs to further penetrate the diseased tissue. Therefore, a sharp spike can be set at the end of the needle core 3 to facilitate the needle core 3 to penetrate the diseased tissue.

[0068] In summary, in order to solve the technical problems of defects in the existing ultrasonic biopsy sampling methods, the ultrasonic endoscopic biopsy instrument proposed in this embodiment first punctures the diseased tissue through the needle tube 2 when used, so that the needle core 3 opens up an active channel in the diseased tissue, and then the cell brush 6 can repeatedly rub the diseased tissue by pushing and pulling the connecting cap 5, so that the diseased tissue exudes more tissue fluid or drops more tissue structures. The cell brush 6 can also collect samples well, thereby collecting sufficient disease samples for pathological analysis.

[0069] The present invention and its embodiments are described schematically above, which is not restrictive. The drawings show only one embodiment of the present invention, and the actual structure is not limited thereto. Therefore, if a person skilled in the art is inspired by it and creatively designs a structure and an embodiment similar to the technical solution without departing from the purpose of the invention, they shall all fall within the protection scope of the present invention.

Claims

1. An ultrasonic endoscopic biopsy instrument, characterized in that: It comprises a handle mechanism (1), a needle tube (2), a needle core (3) and a Luer seat (4); The Luer seat (4) is detachably arranged at one end of the handle mechanism (1); the needle tube (2) is connected to the Luer seat (4) and / or the handle mechanism; the other end of the needle tube (2) extends from the other end of the handle mechanism (1) to the outside; the needle tube (2) is hollow inside, and the needle tube (2) is connected to the Luer seat (4); A connecting cap (5) is fixedly provided at one end of the needle core (3), the connecting cap (5) is sleeved on the outside of the Luer seat (4) and movably cooperates with the Luer seat (4), and the needle core (3) passes through the inner cavity of the Luer seat (4) and the needle tube (2); An opening communicating with the outside is arranged at one end of the needle tube (2) away from the Luer seat (4); a brush section (30) is arranged at the end of the needle core (3); and a plurality of bundles of cell brushes (6) are arranged along the brush section (30); the length of the needle core (3) is greater than the length of the needle tube (2), so that the brush section (30) can extend out of the needle tube (2) through the opening.

2. The ultrasonic endoscopic biopsy instrument according to claim 1, characterized in that: The handle mechanism (1) comprises an intermediate rod (10), wherein the intermediate rod (10) comprises a first segment (101) and a second segment (102) which are adjacent to each other; The first segment (101) is sleeved with a first sliding sleeve rod (11) on its outer side, the Luer seat (4) is arranged at one end of the first sliding sleeve rod (11), and a first locking member (13) is arranged between the first sliding sleeve rod (11) and the first segment (101); A second sliding sleeve rod (12) is sleeved on the outer side of the second segment (102); an outer sheath tube (14) is fixedly provided at the end of the second segment (102); a lead-out sheath (15) is fixedly provided at the end of the second sliding sleeve rod (12); the lead-out sheath (15) is sleeved on the outer side of the outer sheath tube (14); the outer sheath tube (14) is sleeved on the outer side of the needle tube (2); and a second locking member (16) is provided between the second sliding sleeve rod (12) and the second segment (102).

3. An ultrasonic endoscopic biopsy instrument according to claim 2, characterized in that: At least one of the first segment (101), the second segment (102) and the Luer seat (4) is provided with scale marks.

4. The ultrasonic endoscopic biopsy instrument according to claim 1, characterized in that: The Luer seat (4) is snap-fitted to the handle mechanism (1).

5. The ultrasonic endoscopic biopsy instrument according to claim 1, characterized in that: It also comprises a protective sleeve (70), one end of which is fixedly provided with an assembly end block (71), the assembly end block (71) being restricted in the handle mechanism (1) through the Luer seat (4), and the needle tube (2) passing through the assembly end block (71) so that the protective sleeve (70) is sleeved on the outside of the needle tube (2); A snap-fitting cavity (710) is provided in the assembly end block (71), an elastic ring (73) is provided at one end of the snap-fitting cavity (710) away from the Luer seat (4), a boss (31) is fixedly provided on the needle tube (2), the snap-fitting cavity (710) is used to accommodate the boss (31), and when the boss (31) is located in the snap-fitting cavity (710), the elastic ring (73) is used to limit the boss (31) from moving in a direction away from the Luer seat (4); Wherein, the distance between the boss (31) and the needle tip of the needle tube (2) is less than or equal to the length of the protective sleeve (70).

6. The ultrasonic endoscopic biopsy instrument according to claim 1, characterized in that: The cell brushes (6) adjacent to each other in the front and rear directions along the length direction of the brush section (30) are aligned or staggered.

7. The ultrasonic endoscopic biopsy instrument according to claim 1, characterized in that: There is a spacing a between the cell brushes (6) that can overlap after falling down in the axial direction of the needle core (3), and the spacing a is greater than half the length of a single bundle of the cell brushes (6) and less than the length of a single bundle of the cell brushes (6).

8. The ultrasonic endoscopic biopsy instrument according to claim 1, characterized in that: The diameter of the brush section (30) is smaller than the diameter of the needle core (3).

9. The ultrasonic endoscopic biopsy instrument according to claim 1, characterized in that: The brush section (30) is provided with a plurality of grooves (32). When the cell brush (6) falls over, the grooves (32) are used to accommodate the adjacent fallen cell brushes (6).

10. The ultrasonic endoscopic biopsy instrument according to claim 1, characterized in that: The length of the cell brush (6) gradually decreases from the end of the needle core (3) toward the connecting cap (5).

11. The ultrasonic endoscopic biopsy instrument according to claim 1, characterized in that: The length of the cell brush (6) gradually decreases from the two ends of the brush section (30) to the middle.

12. The ultrasonic endoscopic biopsy instrument according to claim 1, characterized in that: A scraping portion (33) is provided on the brush segment (30) and / or on the needle core (3) near the brush segment (30).

13. The ultrasonic endoscopic biopsy instrument according to claim 1, characterized in that: The end of the needle core (3) is provided with a spike end (34).

14. An ultrasonic endoscopic biopsy instrument according to any one of claims 1 to 13, characterized in that: The cell brush (6) is made of polymer material.

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