Rhodomyrtus tomentosa extract for repairing UVB damage as well as preparation method and application of rhodomyrtus tomentosa extract

By preparing myrtle ethyl acetate extract, the problem of difficulty in effectively repairing UVB-induced skin damage at the cellular level in the prior art is solved, effective repair of UVB damage is achieved, cell resistance is enhanced, and cell apoptosis rate is significantly reduced.

CN119679675APending Publication Date: 2025-03-25SOUTH CHINA BOTANICAL GARDEN CHINESE ACADEMY OF SCI
0 Cites 0 Cited by

Patent Information

Application Number
CN202411897661.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-23
Publication Date
2025-03-25

AI Technical Summary

Technical Problem

The prior art is difficult to effectively repair skin damage caused by ultraviolet rays (UVB) at the cellular level, especially in terms of enhancing the ability of cells to resist UVB and in-depth repair of increased radicals and cellular DNA damage.

Method used

By preparing Myrtle crude extract, especially ethyl acetate extract, it is used to repair HaCaT cell damage caused by medium wave ultraviolet (UVB) radiation. The method includes crushing the myrtle fruit, adding an extractant for leaching, concentrating under reduced pressure and extraction to obtain an extract with antioxidant and repairing effects.

Benefits of technology

Myrtle ethyl acetate extract can effectively inhibit the production of reactive oxygen species (ROS) caused by UVB radiation, reduce cell apoptosis, significantly improve cell survival, and significantly reduce cell apoptosis after UVB damage.

✦ Generated by Eureka AI based on patent content.
Patent Text Reader

Abstract

The invention discloses a rhodomyrtus tomentosa extract for repairing UVB damage as well as a preparation method and application of the rhodomyrtus tomentosa extract. Particularly, the EA extract can significantly improve the survival rate of HaCaT cells damaged by UVB and effectively inhibit cell apoptosis. According to the invention, an in-vitro experiment is taken as a core, human immortalized keratinocyte HaCaT is selected as a model, the damage of ultraviolet rays to skin epidermis is simulated through an ultraviolet lamp, and the rhodomyrtus tomentosa extract is taken as a repairing agent to systematically detect key indexes such as cell survival rate and apoptosis rate, so that the potential effect of the rhodomyrtus tomentosa extract in ultraviolet damage repairing is discussed. The invention not only lays a theoretical foundation for ultraviolet damage repair and research and development of antioxidants, but also provides a scientific basis for development and application of natural plant resources such as rhodomyrtus tomentosa fruits and the like.
Need to check novelty before this filing date? Find Prior Art