A patch for relieving joint pain and preparation method thereof

By preparing a patch containing a variety of Chinese medicinal materials and specific substrates, the existing patch treatment types are solved, and the problems of single treatment types and skin damage are achieved, effectively alleviating various joint pain types and promoting drug absorption.

CN119733030APending Publication Date: 2025-04-01GUILIN WANDOM MEDICAL APP CO LTD
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Patent Information

Application Number
CN202411966103.3
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-30
Publication Date
2025-04-01

AI Technical Summary

Technical Problem

The existing patches used to relieve joint pain have problems such as single treatment types, poor marginal effects, use of toxic Chinese medicinal materials and long-term use to cause cold evil accumulation.

Method used

A patch formula including sulfate ore powder, blood depletion powder, honey ephedra powder, vinegar yeast powder, Chuanxiong powder, Pueraria root powder, Weilingxian powder, Eucommia powder, Camphor powder, dried ginger powder, licorice powder, glycerin, propylene glycol, vanilla butyl ether, water-soluble azone, carboxymethylcellulose sodium, Vaseline, beeswax, water and 95% alcohol was prepared by stirring and heating.

Benefits of technology

This patch can effectively relieve joint pain caused by poor blood circulation, cold evil entering the body and rheumatism pain, and promote drug absorption and prolong product effectiveness through the use of self-heating agents and matrix materials.

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Abstract

The invention discloses a patch for relieving joint pain and a preparation method thereof. The patch comprises the following components: 9600-10800 parts of sulfate ore powder, 129-200 parts of dragon's blood powder, 129-200 parts of honey ephedra powder, 200-300 parts of vinegar corydalis powder, 200-300 parts of chuanxiong powder, 300-500 parts of kudzu root powder, 200-400 parts of clematis powder, 200-300 parts of eucommia powder, 100-200 parts of camphor powder, 500-1000 parts of dried ginger powder, 200-300 parts of liquorice powder, 1050 parts of glycerin, 900 parts of propylene glycol, 18 parts of vanillyl butyl ether, 36 parts of water-soluble azone, 96 parts of sodium carboxymethylcellulose, 816 parts of vaseline, 84 parts of yellow beeswax, 600 parts of water and 150 parts of 95% alcohol. Using vinegar-corydalis and Xuejie to treat joint pain caused by poor blood circulation, dried ginger and Clematis to treat joint pain caused by cold evil entering the body, and honey-coated ephedra and Chuanxiong to treat joint pain caused by rheumatism can more effectively relieve joint pain in various conditions.
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Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicine, and in particular to a patch for relieving joint pain and a preparation method thereof. Background Art

[0002] There are many causes of joint pain in life, including inflammation caused by soft tissue wear, pain caused by systemic lupus erythematosus, and allergic purpura caused by overwork. The degree of pain caused by joint pain is also different. Mild joint pain can be relieved by moving the joints or applying hot compresses; moderate pain has a cutting or burning sensation, which requires medication or surgery; severe pain has a colic feeling. According to the World Health Organization, the incidence of joint pain in the elderly aged 60 is as high as 78.5%. China is a hard-hit area for joint pain, with more than 100 million people suffering from knee pain. According to data, some joint pains such as gouty arthritis and soft tissue wear caused by overwork are becoming younger.

[0003] Joint pain is often accompanied by joint swelling. In traditional Chinese medicine theory, joint pain can be divided into meridian blockage caused by rheumatism, poor blood circulation caused by blood stasis, and blocked meridians caused by cold evil entering the body.

[0004] There are various joint pain relief patch products on the market, and the problems are as follows:

[0005] 1. The treatment of joint pain is relatively single type, and it does not have a good therapeutic effect on other types of joint pain.

[0006] 2. Using medicinal wine or alcohol extracts as the main ingredients will cause certain damage to the skin.

[0007] 3. Repeated use has a certain marginal effect and the effect is poor.

[0008] 4. Using poisonous Chinese medicinal materials such as Aconitum kusnezoffii and Aconitum carmichaelii can easily cause allergic reactions or poisoning if used for a long time.

[0009] 5. Some products use cooling drugs, and long-term use can easily lead to accumulation of cold evil in the body, making joint pain more severe. Summary of the invention

[0010] The invention aims to provide a patch for relieving joint pain and a preparation method thereof.

[0011] To achieve the above purpose, the present invention adopts a patch for relieving joint pain, which comprises the following components: 9600-10800 parts of sulfate ore powder, 129-200 parts of dragon's blood powder, 129-200 parts of honey ephedra powder, 200-300 parts of vinegar corydalis powder, 200-300 parts of chuanxiong powder, 300-500 parts of kudzu root powder, 200-400 parts of clematis powder, 200-300 parts of eucommia powder, 100-200 parts of camphor powder, 500-1000 parts of dried ginger powder, 200-300 parts of liquorice powder, 1050 parts of glycerin, 900 parts of propylene glycol, 18 parts of vanillyl butyl ether, 36 parts of water-soluble azone, 96 parts of sodium carboxymethylcellulose, 816 parts of vaseline, 84 parts of yellow beeswax, 600 parts of water, and 150 parts of 95% alcohol.

[0012] The present invention also provides a method for preparing a patch for relieving joint pain, comprising the patch for relieving joint pain, and the preparation steps are as follows:

[0013] Step 1: Weigh 6 parts of sodium carboxymethylcellulose and add 600 parts of water to soak;

[0014] Step 2: Weigh 816 parts of vaseline and 84 parts of yellow beeswax, heat to melt, and stir evenly;

[0015] Step 3: Weigh the sulfate ore, crush it, pass it through a 200-mesh sieve, and take 9600-10800 portions for later use;

[0016] Step 4: Take 129-200 parts of Dragon's Blood powder, 129-200 parts of honey ephedra powder, 200-300 parts of vinegar Corydalis powder, 200-300 parts of Chuanxiong powder, 300-500 parts of Pueraria powder, 200-400 parts of Clematis powder, 200-300 parts of Eucommia powder, 100-200 parts of camphor powder, 500-1000 parts of dried ginger powder, and 200-300 parts of liquorice powder, mix them evenly for later use, and pass the above Chinese medicinal material powders through a 200-mesh sieve;

[0017] Step 5: Add Chinese herbal medicine powder and sulfate ore powder into a mixing tank and stir for 20 minutes;

[0018] Step 6: Weigh 1050 parts of glycerol, add it into the stirring tank, and stir for 10 minutes;

[0019] Step 7: Weigh 900 parts of propylene glycol and stir for 10 minutes;

[0020] Step 8: Weigh the remaining 90 parts of sodium carboxymethyl cellulose, add it into the stirring tank, and stir for 10 minutes;

[0021] Step 9: Add the vaseline base obtained in step 2, maintain the temperature at 50°C, and stir for 10 minutes;

[0022] Step 10: Weigh 150 parts of 95% alcohol, add to the mixing tank, and stir for 10 minutes;

[0023] Step 11: Add the 1% sodium carboxymethylcellulose solution obtained in step 1 and stir for 30 minutes;

[0024] Step 12: Place in a specific mold and cool to set.

[0025] The invention has the following beneficial effects: using vinegar Corydalis and Dragon's Blood to treat joint pain caused by poor blood circulation, using dried ginger and Clematis to treat joint pain caused by cold pathogens entering the body, and using honey Ephedra and Chuanxiong to treat joint pain caused by rheumatic pain, can more effectively relieve joint pain in various cases. In addition, adding water-soluble azone and vanillyl butyl ether as dressings can well heat the applied part, promote blood flow and skin absorption of drugs; using yellow beeswax and vaseline as the matrix, adding 95% ethanol after heating and melting can well prevent microbial growth, and can effectively extend the shelf life of the product. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0027] Figure 1 It is a process flow chart of a specific embodiment 1 of a patch for relieving joint pain and a preparation method thereof of the present invention.

[0028] Figure 2 It is a process flow chart of specific embodiment 2 of a patch for relieving joint pain and a preparation method thereof of the present invention.

[0029] Figure 3 It is a process flow chart of specific embodiment 3 of a patch for relieving joint pain and a preparation method thereof of the present invention. DETAILED DESCRIPTION

[0030] Embodiments of the present invention are described in detail below, examples of which are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, and should not be construed as limiting the present invention.

[0031] See also Figures 1 to 3 The present invention provides three specific embodiments of a patch for relieving joint pain and a preparation method thereof. Specific embodiment 1:

[0033] Formula components: 9600-10800 parts of sulfate ore powder, 200 parts of dragon's blood powder, 129 parts of honey ephedra powder, 300 parts of vinegar Corydalis powder, 200 parts of Chuanxiong powder, 300-500 parts of Pueraria powder, 200 parts of Clematis powder, 200-300 parts of Eucommia powder, 100-200 parts of camphor powder, 500 parts of dried ginger powder, 200-300 parts of licorice powder, 1050 parts of glycerin, 900 parts of propylene glycol, 18 parts of vanillyl butyl ether, 36 parts of water-soluble azone, 96 parts of sodium carboxymethylcellulose, 816 parts of vaseline, 84 parts of yellow beeswax, 600 parts of water, and 150 parts of 95% alcohol.

[0034] S101: Preparation of 1% sodium carboxymethylcellulose solution: According to the formula components, weigh 6 parts of sodium carboxymethylcellulose and add 600 parts of water to soak.

[0035] S102: Preparation of vaseline matrix: According to the formula components, weigh vaseline and yellow beeswax, heat to melt, and stir evenly.

[0036] S103: Preparation of ore powder: According to the formula components, weigh the sulfate ore, crush it and pass it through a 200-mesh sieve, and take 10,800 portions for later use.

[0037] S104: Preparation of Chinese herbal medicine powder: according to the formula components, take the purified and processed Dragon's Blood, Honey Ephedra, Vinegar Corydalis, Chuanxiong, Pueraria, Clematis, Eucommia, Camphor, Dried Ginger and Licorice medicinal materials, grind them and pass through a 200-mesh sieve; according to the formula components, take 200 parts of Dragon's Blood powder, 129 parts of Honey Ephedra powder, 300 parts of Vinegar Corydalis powder, 200 parts of Chuanxiong powder, 300-500 parts of Pueraria powder, 200 parts of Clematis powder, 200 parts of Eucommia powder, 100-200 parts of camphor powder, 500 parts of dried ginger powder and 200-300 parts of licorice powder, stir well and set aside.

[0038] S105: Mixing: Add Chinese medicinal material powder and sulfate ore powder into a mixing tank and stir for 20 minutes.

[0039] S106: Add glycerol: According to the formula components, weigh 1050 parts of glycerol, add it into the stirring tank, and stir for 10 minutes.

[0040] S107: Add propylene glycol: According to the formula components, weigh 900 parts of propylene glycol and stir for 10 minutes.

[0041] S108: Adding sodium carboxymethyl cellulose: According to the formula components, weigh the remaining 90 parts of sodium carboxymethyl cellulose, add it into the stirring tank, and stir for 10 minutes.

[0042] S109: Adding vaseline base: Add the vaseline base in step S102, maintain the temperature at 50° C., and stir for 10 minutes.

[0043] S1010: Add alcohol: According to the formula components, weigh 150 parts of 95% alcohol, add it into the mixing tank, and stir for 10 minutes.

[0044] S1011: Adding sodium carboxymethyl cellulose solution: Add the 1% sodium carboxymethyl cellulose solution in step S101 and stir for 30 minutes.

[0045] S1012: Shaping: Place in a specific mold, cool and shape to obtain the finished product. Specific embodiment 2:

[0047] Formula components: 9600-10800 parts of sulfate ore powder, 129 parts of dragon's blood powder, 200 parts of honey ephedra powder, 200 parts of vinegar Corydalis powder, 300 parts of Chuanxiong powder, 300-500 parts of Pueraria powder, 200 parts of Clematis powder, 200-300 parts of Eucommia powder, 100-200 parts of camphor powder, 500 parts of dried ginger powder, 200-300 parts of licorice powder, 1050 parts of glycerin, 900 parts of propylene glycol, 18 parts of vanillyl butyl ether, 36 parts of water-soluble azone, 96 parts of sodium carboxymethylcellulose, 816 parts of vaseline, 84 parts of yellow beeswax, 600 parts of water, and 150 parts of 95% alcohol.

[0048] S201: Preparation of 1% sodium carboxymethylcellulose solution: According to the formula components, weigh 6 parts of sodium carboxymethylcellulose and add 600 parts of water to soak.

[0049] S202: Preparation of vaseline matrix: According to the formula components, weigh vaseline and yellow beeswax, heat to melt, and stir evenly.

[0050] S203: Preparation of ore powder: According to the formula components, weigh the sulfate ore, crush it and pass it through a 200-mesh sieve, and take 10,800 portions for later use.

[0051] S204: Preparation of Chinese herbal medicine powder: according to the formula components, take the purified and processed Dragon's Blood, Honey Ephedra, Vinegar Corydalis, Chuanxiong, Pueraria, Clematis, Eucommia, Camphor, Dried Ginger and Licorice medicinal materials, grind them and pass through a 200-mesh sieve; according to the formula components, take 129 parts of Dragon's Blood powder, 200 parts of Honey Ephedra powder, 200 parts of Vinegar Corydalis powder, 300 parts of Chuanxiong powder, 300-500 parts of Pueraria powder, 200 parts of Clematis powder, 200 parts of Eucommia powder, 100-200 parts of camphor powder, 500 parts of dried ginger powder and 200-300 parts of licorice powder, stir well and set aside.

[0052] S205: Mixing: Add Chinese medicinal material powder and sulfate ore powder into a mixing tank and stir for 20 minutes.

[0053] S206: Add glycerol: According to the formula components, weigh 1050 parts of glycerol, add it into the stirring tank, and stir for 10 minutes.

[0054] S207: Add propylene glycol: According to the formula components, weigh 900 parts of propylene glycol and stir for 10 minutes.

[0055] S208: Adding sodium carboxymethyl cellulose: According to the formula components, weigh the remaining 90 parts of sodium carboxymethyl cellulose, add it into the stirring tank, and stir for 10 minutes.

[0056] S209: Adding vaseline base: Add the vaseline base in step S202, maintain the temperature at 50° C., and stir for 10 minutes.

[0057] S2010: Add alcohol: According to the formula components, weigh 150 parts of 95% alcohol, add it into the mixing tank, and stir for 10 minutes.

[0058] S2011: Adding sodium carboxymethyl cellulose solution: Add the 1% sodium carboxymethyl cellulose solution in step S201 and stir for 30 minutes.

[0059] S2012: Shaping: Place in a specific mold, cool and shape to get the finished product. Specific embodiment 3:

[0061] Formula components: 9600-10800 parts of sulfate ore powder, 129 parts of dragon's blood powder, 129 parts of honey ephedra powder, 200 parts of vinegar Corydalis powder, 200 parts of Chuanxiong powder, 300-500 parts of Pueraria powder, 400 parts of Clematis powder, 200-300 parts of Eucommia powder, 100-200 parts of camphor powder, 1000 parts of dried ginger powder, 200-300 parts of licorice powder, 1050 parts of glycerin, 900 parts of propylene glycol, 18 parts of vanillyl butyl ether, 36 parts of water-soluble azone, 96 parts of sodium carboxymethylcellulose, 816 parts of vaseline, 84 parts of yellow beeswax, 600 parts of water, and 150 parts of 95% alcohol.

[0062] S301: Preparation of 1% sodium carboxymethylcellulose solution: According to the formula components, weigh 6 parts of sodium carboxymethylcellulose and add 600 parts of water to soak.

[0063] S302: Preparation of vaseline matrix: According to the formula components, weigh vaseline and yellow beeswax, heat to melt, and stir evenly.

[0064] S303: Preparation of ore powder: According to the formula components, weigh the sulfate ore, crush it and pass it through a 200-mesh sieve, and take 10,800 portions for later use.

[0065] S304: Preparation of Chinese herbal medicine powder: according to the formula components, take the purified and processed Sanguisorba officinalis, honey ephedra, vinegar Corydalis yanhusuo, Chuanxiong, Pueraria root, Clematidis, Eucommia bark, camphor, dried ginger and licorice medicinal materials, grind them and pass through a 200-mesh sieve, according to the formula components, take 129 parts of Sanguisorba officinalis powder, 129 parts of honey ephedra powder, 200 parts of vinegar Corydalis yanhusuo powder, 200 parts of Chuanxiong powder, 300-500 parts of Pueraria root powder, 400 parts of Clematidis powder, 200-300 parts of Eucommia bark powder, 100-200 parts of camphor powder, 1000 parts of dried ginger powder and 200-300 parts of licorice powder, mix them evenly and set aside.

[0066] S305: Mixing: Add Chinese medicinal material powder and sulfate ore powder into a mixing tank and stir for 20 minutes.

[0067] S306: Add glycerol: According to the formula components, weigh 1050 parts of glycerol, add it into the stirring tank, and stir for 10 minutes.

[0068] S307: Add propylene glycol: According to the formula components, weigh 900 parts of propylene glycol and stir for 10 minutes.

[0069] S308: Adding sodium carboxymethyl cellulose: According to the formula components, weigh the remaining 90 parts of sodium carboxymethyl cellulose, add it into the stirring tank, and stir for 10 minutes.

[0070] S309: Adding vaseline base: Add the vaseline base in step S302, maintain the temperature at 50° C., and stir for 10 minutes.

[0071] S3010: Add alcohol: According to the formula components, weigh 150 parts of 95% alcohol, add it into the mixing tank, and stir for 10 minutes.

[0072] S3011: Adding sodium carboxymethyl cellulose solution: Add the 1% sodium carboxymethyl cellulose solution in step S301 and stir for 30 minutes.

[0073] S3012: Shaping: Place in a specific mold, cool and shape to get the finished product.

[0074] The following is a description of the main effects of the raw materials in Examples 1 to 3:

[0075] Xuejie can promote blood circulation and relieve pain, dissipate blood stasis and stop bleeding, and has a good effect on relieving joint pain caused by poor blood circulation;

[0076] Honeyed ephedra can induce sweating and dispel cold. After being processed with honey, the original toxicity of ephedra is alleviated and it is not easy to cause skin allergies.

[0077] Vinegar-corydalis can be used to invigorate blood circulation and promote qi movement. After being processed with vinegar, it can promote blood and qi movement. It has a better effect when used together with Xuejie.

[0078] Chuanxiong can invigorate blood circulation, promote qi circulation, dispel wind and relieve pain. When combined with honey ephedra and licorice, it can effectively relieve rheumatic pain.

[0079] Pueraria root is used to relieve muscle pain, reduce fever, promote blood circulation, and relieve joint pain.

[0080] Clematis is used to dispel rheumatism and dredge meridians. When used, it can ensure that the drug is absorbed smoothly and effectively without causing a violent reaction in the body.

[0081] Eucommia is used to strengthen bones and muscles, and is good at strengthening the body after relieving joint pain;

[0082] Camphor is used to stimulate the epidermis, allowing the drug ingredients to be better absorbed;

[0083] Dried ginger can warm the middle and dispel cold, and has a good effect on joint pain caused by cold evil entering the body;

[0084] Licorice can harmonize the medicinal properties and promote the subsequent recovery of the body;

[0085] Water-soluble azone and vanillyl butyl ether are self-heating agents that can be used with other medicinal materials to promote the absorption of medicinal materials and the heating of the body;

[0086] Glycerin, propylene glycol, vaseline, yellow beeswax, and sodium carboxymethylcellulose are commonly used bases. When used together, they can form a non-breakable ointment and make the drug powder more evenly dispersed.

[0087] In summary, the main difference between the embodiments is that the quantities of some medicinal materials used are different, so that they are mainly used to treat different diseases, as follows:

[0088] The joint patch prepared in Example 1 is mainly used for joint pain caused by poor blood circulation.

[0089] The joint patch prepared in Example 2 is mainly used for joint pain caused by rheumatism.

[0090] The joint patch prepared in Example 3 is mainly used for joint pain caused by the invasion of pathogenic cold into the body.

[0091] The patch for relieving joint pain of the present invention has the following characteristics:

[0092] 1. This product is based on traditional Ma Gan Tang and medicinal wine for traumatic injuries, combined with practical experience, and adds medicinal materials to make the effect better;

[0093] 2. Use vaseline and yellow beeswax as ointment base to facilitate storage and transportation;

[0094] 3. The sulfate ore powder and yellow beeswax are both special Zhuang medicines in Guangxi, with many years of experience in use. They are mainly used to promote blood circulation, nourish qi, and resist bacteria and inflammation;

[0095] 4. Adding self-heating agents such as vanillyl butyl ether and water-soluble azone can be suitable for weak patients to promote sweating, raise yang and promote blood circulation;

[0096] 5. Glycerin, as a common wetting agent, can keep the skin comfortable, and when combined with sodium carboxymethylcellulose, it can absorb various drug powders and make them evenly dispersed;

[0097] 6. When using, apply the patch to the painful joints. You can use it according to actual requirements. Use it once a day, 1 patch each time, and apply it for 3 hours each time until the joint pain symptoms are relieved. It can also be used in combination with traditional Chinese medicine methods such as foot bath, massage, acupuncture, or according to personal needs. Children must use it under the doctor's advice.

[0098] What is disclosed above is only a preferred embodiment of the present invention, and it certainly cannot be used to limit the scope of rights of the present invention. Ordinary technicians in this field can understand that all or part of the processes of the above embodiment and equivalent changes made according to the claims of the present invention still fall within the scope of the invention.

Claims

1. A patch for relieving joint pain, characterized in that: The invention comprises the following ingredients: 9600-10800 parts of sulfate ore powder, 129-200 parts of dragon's blood powder, 129-200 parts of honey ephedra powder, 200-300 parts of vinegar corydalis powder, 200-300 parts of chuanxiong powder, 300-500 parts of kudzu root powder, 200-400 parts of clematis powder, 200-300 parts of eucommia powder, 100-200 parts of camphor powder, 500-1000 parts of dried ginger powder, 200-300 parts of licorice powder, 1050 parts of glycerin, 900 parts of propylene glycol, 18 parts of vanillyl butyl ether, 36 parts of water-soluble azone, 96 parts of sodium carboxymethyl cellulose, 816 parts of vaseline, 84 parts of yellow beeswax, 600 parts of water and 150 parts of 95% alcohol.

2. A method for preparing a patch for relieving joint pain, comprising the patch for relieving joint pain according to claim 1, characterized in that: The preparation steps are as follows: Step 1: Weigh 6 parts of sodium carboxymethylcellulose and add 600 parts of water to soak; Step 2: Weigh 816 parts of vaseline and 84 parts of yellow beeswax, heat to melt, and stir evenly; Step 3: Weigh the sulfate ore, crush it, pass it through a 200-mesh sieve, and take 9600-10800 portions for later use; Step 4: Take 129-200 parts of Dragon's Blood powder, 129-200 parts of honey ephedra powder, 200-300 parts of vinegar Corydalis powder, 200-300 parts of Chuanxiong powder, 300-500 parts of Pueraria powder, 200-400 parts of Clematis powder, 200-300 parts of Eucommia powder, 100-200 parts of camphor powder, 500-1000 parts of dried ginger powder, and 200-300 parts of liquorice powder, mix them evenly for later use, and pass the above Chinese medicinal material powders through a 200-mesh sieve; Step 5: Add Chinese herbal medicine powder and sulfate ore powder into a mixing tank and stir for 20 minutes; Step 6: Weigh 1050 parts of glycerol, add it into the stirring tank, and stir for 10 minutes; Step 7: Weigh 900 parts of propylene glycol and stir for 10 minutes; Step 8: Weigh the remaining 90 parts of sodium carboxymethyl cellulose, add it into the stirring tank, and stir for 10 minutes; Step 9: Add the vaseline base obtained in step 2, maintain the temperature at 50°C, and stir for 10 minutes; Step 10: Weigh 150 parts of 95% alcohol, add to the mixing tank, and stir for 10 minutes; Step 11: Add the 1% sodium carboxymethylcellulose solution obtained in step 1 and stir for 30 minutes; Step 12: Place in a specific mold and cool to set.