High-adhesion restoration and manufacturing method thereof

Abstract

The invention provides a high-adhesion restoration and a manufacturing method thereof, the restoration comprises a substrate layer (101), and the substrate layer (101) is provided with a plurality of protruding structures (1012) perpendicular to the surface (1011) of the substrate layer. The prosthesis is adhered to an abutment through an adhesive, the adhesive fills gaps among the plurality of protruding structures (1012) and gaps between the prosthesis and the abutment, the dental prosthesis is manufactured by combining a CAD / CAM technology with a 3D printing technology, manufacturing of tiny and precise structures is achieved, machining precision is improved, and material waste is reduced; specific tiny protrusions are designed on a traditional restoration CAD design file, so that the bonding area of a restoration bonding surface and an adhesive is increased, the restoration bonding strength is improved, the falling-off rate of the dental restoration is reduced, and mechanical damage and crystalline phase transformation caused by a traditional sand blasting method to an inner crown are avoided.

Description

Technical Field

[0001] The invention relates to the technical field of oral restoration, and in particular to a high-adhesion restoration and a manufacturing method thereof. Background Art

[0002] Tooth defects, edentulous teeth and missing teeth are the three most common diseases in oral rehabilitation. Zirconia, as an inert polycrystalline ceramic, has high mechanical strength and excellent biocompatibility. It has good aesthetic effects when used as an oral restoration material. It has been widely used in the fields of full crown restoration of tooth defects, fixed bridge restoration of edentulous teeth and implant restoration.

[0003] Zirconia compounds have three crystal phases: monoclinic, tetragonal and cubic. In order to stabilize its crystal phase during the ceramic sintering process, a certain amount of metal ion oxides needs to be added as stabilizers, such as calcium oxide, yttrium oxide, strontium oxide, cerium oxide, etc. 3% yttrium oxide stabilized zirconium oxide (3Y-YTZ) has a low sintering temperature, high hardness, strength and toughness, and is currently the most important zirconium oxide material for clinical application. At present, zirconium oxide restorations are mainly made by computer-aided design / computer-aided manufacturing technology (CAM / CAM technology) combined with milling methods, but this technology causes a large waste of materials, and the processable form is limited by the size of the milling cutter head, making it difficult to make some complex or hollow structures. Because the chemical properties of zirconium oxide are very stable, unlike metals, it cannot form micropores through acid etching to achieve mechanical locking with adhesives, nor can it use silane coupling agents to increase chemical bonding. Therefore, the bonding strength of zirconium oxide restorations on teeth is low, and the shedding rate is high during clinical use. At present, the bonding performance of zirconia restorations is mainly improved by sandblasting, that is, using a sandblasting machine to spray Al2O3 particles of a certain size on the inner surface of zirconia (i.e., the bonding surface with the abutment) at a certain pressure. 2 O 3 The particles create tiny holes on the inner surface of zirconia to roughen the bonding surface, thereby increasing the bonding area and improving mechanical locking. However, even with the sandblasting method, the bonding strength is still not ideal, and sandblasting will cause tiny defects on the surface of the zirconia restoration, inducing the transformation of tetragonal zirconia crystals to monoclinic phase, thereby reducing its mechanical properties.

[0004] Therefore, there is still a need to develop new methods for making dental restorations, which can improve the bonding strength of restorations by manufacturing tiny and precise structures, thereby reducing the rate of restoration shedding. Summary of the invention

[0005] The present invention aims to solve one of the technical problems in the related art at least to a certain extent.

[0006] Therefore, in a first aspect of the present invention, the present invention provides a tooth restoration. According to an embodiment of the present invention, the restoration comprises: a base layer (101), wherein the base layer (101) has a plurality of protrusion structures (1012) inclined and / or perpendicular to the inner surface (1011) of the base layer.

[0007] In a second aspect of the present invention, the present invention provides a method for manufacturing a dental restoration. According to an embodiment of the present invention, the method comprises: obtaining a base layer, wherein the base layer has a plurality of protrusion structures inclined and / or perpendicular to the inner surface of the base layer.

[0008] The beneficial effects of the present invention include at least:

[0009] (1) CAD / CAM technology combined with 3D printing technology is used for auxiliary manufacturing, avoiding the restrictions of the milling cutter head on the structure, thereby realizing the manufacturing of small and precise structures, improving the processing accuracy, and reducing material waste;

[0010] (2) The present invention increases the bonding area between the inner surface of the tooth restoration (or zirconium oxide) and the adhesive by designing a specific number and height of micro-protrusions on the traditional zirconia inner crown CAD design file, thereby improving the bonding strength of the restoration and avoiding mechanical damage and crystal phase transformation caused by the traditional sandblasting method to the zirconia inner crown;

[0011] (3) The manufacturing method of the dental restoration proposed in the present application is suitable for the production of most zirconia dental restorations, and can be used to produce single crowns, linked crowns, crown bridges, implant crown restorations, etc., and plays an important role in the field of oral restoration.

[0012] Additional aspects and advantages of the present invention will be given in part in the following description and in part will be obvious from the following description, or will be learned through practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] The above and / or additional aspects and advantages of the present invention will become apparent and easily understood from the description of the embodiments in conjunction with the following drawings, in which:

[0014] Figure 1 The structure diagram of the tooth restoration in the embodiment of the present invention is shown, wherein

[0015] Figure A shows a schematic diagram of the outer surface of the base layer of a dental restoration;

[0016] Figure B shows a schematic diagram of the inner surface of the base layer of a tooth restoration and the protrusion structure thereon;

[0017] Figure C shows a magnified view of the protrusion structure on the inner surface of the tooth restoration;

[0018] Figure 2 A schematic diagram showing the shear test of each group of zirconia discs in Example 1 of the present invention is shown;

[0019] Figure 3 The schematic diagram shows the structure of a microstructured zirconia disc with a protrusion height of 0.05 mm in Example 1 of the present invention. DETAILED DESCRIPTION

[0020] The embodiments of the present invention are described in detail below. The embodiments described below are exemplary and are only used to explain the present invention, and should not be construed as limiting the present invention.

[0021] It should be noted that the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. Further, in the description of the present invention, unless otherwise specified, the meaning of "plurality" is two or more.

[0022] The endpoints and any values ​​of the ranges disclosed in this article are not limited to the precise ranges or values, and these ranges or values ​​should be understood to include values ​​close to these ranges or values. For numerical ranges, the endpoint values ​​of each range, the endpoint values ​​of each range and the individual point values, and the individual point values ​​can be combined with each other to obtain one or more new numerical ranges, which should be considered as specifically disclosed in this article.

[0023] In order to make the present invention more easily understood, certain technical and scientific terms are specifically defined below. Unless otherwise clearly defined elsewhere in this document, all other technical and scientific terms used herein have the meanings commonly understood by those skilled in the art to which the present invention belongs.

[0024] In this document, the terms “include” or “comprising” are open expressions, that is, including the contents specified in the present invention but not excluding other contents.

[0025] As used herein, the terms "optionally", "optional" or "optionally" generally mean that the subsequently described event or circumstance may but need not occur, and that the description includes instances where the event or circumstance occurs and instances where it does not.

[0026] In this article, the term "single crown" refers to a crown restoration designed for a single tooth, usually used to repair damage to a single tooth, such as severe caries, tooth fractures, etc. It can be metal or porcelain. A single crown exists independently and does not rely on the support of other teeth.

[0027] In this article, the term "joint crown" refers to a restoration consisting of a crown and a bridge, which is used to repair abnormal tooth morphology and function caused by caries, trauma or tooth defects. The joint crown can be an all-ceramic joint crown, which is made of all-ceramic materials and has excellent aesthetic properties and biocompatibility. The joint crown is suitable for the case of multiple consecutive tooth defects, and it enhances the overall stability by connecting adjacent teeth.

[0028] In this article, the term "crown and bridge (bridge crown or fixed bridge)" is a restoration that uses the natural teeth or post and core on both sides of the missing tooth as abutment teeth and an artificial bridge body to improve the shape and function of the missing tooth. It is like a bridge, connecting the abutment teeth at both ends and supporting the missing part in the middle. It is mainly used to repair missing teeth.

[0029] In this article, the term "implant-over-crown restoration" refers to a crown that is placed on top of an implant to replace a missing natural tooth. It can be a single crown, designed for a single edentulous area, where a single implant is placed to replace the lost natural tooth. An implant-over-crown restoration provides a secure bite and restores the appearance and function of a natural tooth.

[0030] In one aspect, the present invention provides a dental restoration, such as Figure 1 As shown in Figure B, the dental restoration comprises: a base layer (101), and the base layer (101) has a plurality of protrusion structures (1012) inclined and / or perpendicular to the base layer surface (1011). The dental restoration according to the embodiment of the present invention has a specific number and height of micro-protrusions, which increases the bonding area between the inner surface of the dental restoration and the adhesive, improves the bonding strength of the restoration, and avoids mechanical damage and crystal phase transformation caused by traditional sandblasting methods to the zirconia inner crown. The dental restoration can be a single crown, a linked crown, a crown bridge, an implant upper crown restoration, etc., and plays an important role in the field of oral restoration.

[0031] According to an embodiment of the present invention, the above-mentioned dental restoration may further include at least one of the following additional technical features:

[0032] According to some specific embodiments of the present invention, the base layer (101) has a plurality of protrusion structures (1012) perpendicular to the inner surface (1011) of the base layer. In this case, the bonding area between the inner surface (or zirconium oxide) of the tooth restoration and the adhesive is increased, thereby improving the bonding strength of the restoration.

[0033] According to an embodiment of the present invention, the ratio of the total contact area of ​​the plurality of protrusion structures (1012) and the inner surface (1011) of the base layer to the area of ​​the inner surface (1011) of the base layer is 30% to 70%.

[0034] According to some specific embodiments of the present invention, the total contact area of ​​the plurality of protrusion structures (1012) with the inner surface (1011) of the base layer accounts for 50% of the area of ​​the inner surface (1011) of the base layer.

[0035] like Figure 1 In Figure C, h is the vertical distance between the protrusion structure (1012) and the inner surface (1011) of the base layer, and the vertical distance between the protrusion structure (1012) and the inner surface (1011) of the base layer is 0.05-0.1 mm. This vertical distance is the optimized data after screening by the present invention, at which the bonding area between the inner surface (or zirconium oxide) of the tooth restoration and the adhesive is increased, thereby improving the bonding strength of the restoration.

[0036] According to an embodiment of the present invention, the material of the base layer (101) and / or the protruding structure (1012) is at least one of zirconium oxide, metallic titanium, titanium alloy, cobalt-chromium alloy and stainless steel.

[0037] According to an embodiment of the present invention, the restoration is bonded to the abutment by an adhesive. The abutment includes abutments in the process of restoring teeth using a single crown, a combined crown, a crown bridge, or an implant upper crown, such as a single or multiple anterior or posterior teeth with tooth defects, teeth at both ends of a gap in a dentition defect, or an implant restoration abutment.

[0038] According to an embodiment of the present invention, the inner surface (1011) of the base layer is bonded to the abutment by an adhesive.

[0039] According to an embodiment of the present invention, the adhesive fills the gaps between the plurality of protruding structures (1012) and the gaps between the restoration and the abutment.

[0040] like Figure 1 As shown in Figure A in the figure, the restoration also includes a base layer outer surface (1013), and the dental restoration is in contact with the oral cavity through the base layer outer surface (1013).

[0041] In another aspect, the present invention provides a method for manufacturing a dental restoration, the method comprising: obtaining a base layer, the base layer having a plurality of protrusion structures inclined and / or perpendicular to an inner surface of the base layer.

[0042] According to an embodiment of the present invention, the manufacturing method of the above-mentioned dental restoration may further include at least one of the following additional technical features:

[0043] According to an embodiment of the present invention, the base layer (101) has a plurality of protruding structures (1012) perpendicular to the inner surface (1011) of the base layer.

[0044] According to an embodiment of the present invention, the ratio of the total contact area of ​​the plurality of protrusion structures with the inner surface of the base layer to the inner surface area of ​​the base layer is 30% to 70%.

[0045] According to an embodiment of the present invention, the ratio of the total contact area of ​​the plurality of protrusion structures with the inner surface of the base layer to the inner surface area of ​​the base layer is 50%.

[0046] According to an embodiment of the present invention, a vertical distance between the protruding structure and the inner surface of the base layer is 0.05 to 0.1 mm.

[0047] According to an embodiment of the present invention, the material of the restoration is at least one of zirconium oxide, metal titanium, titanium alloy, cobalt-chromium alloy and stainless steel.

[0048] According to an embodiment of the present invention, the restoration is bonded to the abutment by means of an adhesive.

[0049] According to an embodiment of the present invention, the inner surface of the base layer is bonded to the abutment by an adhesive.

[0050] According to an embodiment of the present invention, the adhesive fills the gaps between the plurality of protruding structures and the gap between the restoration and the abutment.

[0051] According to an embodiment of the present invention, the restoration further comprises a base layer outer surface, and the dental restoration contacts the oral cavity through the base layer outer surface.

[0052] According to an embodiment of the present invention, the method comprises: before obtaining the restoration, obtaining restoration data of the tooth to be restored in advance, and designing the restoration based on the restoration data;

[0053] According to an embodiment of the present invention, the restoration data is obtained by: preparing the tooth to be restored, and performing a three-dimensional scan of the prepared tooth by an intraoral scanning device.

[0054] According to an embodiment of the present invention, the restoration data includes at least one of the following: morphology, position and occlusal relationship.

[0055] According to an embodiment of the present invention, the restoration design is performed by three-dimensional design software.

[0056] According to an embodiment of the present invention, the restoration design includes: based on the position, morphology, and occlusal relationship restoration data of the tooth to be restored, dividing the inner surface of the base layer into several triangular facets according to a threshold value, selecting all vertices of the triangular facets, randomly selecting 30% to 70% of the vertices, stretching them by 0.05 mm to 0.1 mm along the normal direction, and then performing turbo smoothing to obtain the design file of the restoration.

[0057] According to an embodiment of the present invention, the threshold value is 0.01-0.1 mm, preferably 0.01 mm.

[0058] Those skilled in the art will appreciate that the 3D design software is not particularly limited, and any 3D design software that can represent the 3D structure of the dental restoration can be used. According to an embodiment of the present invention, the 3D design software includes but is not limited to at least one of the following: CAD, 3ds Max, and SolidWorks.

[0059] According to an embodiment of the present invention, the dental restoration is obtained by printing using a 3D printer based on the restoration design file.

[0060] The scheme of the present disclosure will be explained below in conjunction with the examples. Those skilled in the art will appreciate that the following examples are only used to illustrate the present disclosure and should not be considered to limit the scope of the present disclosure. Where specific techniques or conditions are not indicated in the examples, the techniques or conditions described in the literature in this area or the product instructions are used. Where the manufacturers of reagents or instruments are not indicated, they are all conventional products that can be obtained commercially.

[0061] Example 1

[0062] 1.1 Specimen preparation:

[0063] In this embodiment, smooth zirconia discs (specimens) with a diameter of 14 mm and a height of 2 mm were treated differently to obtain 8 groups of specimens for experimentation. For example, Figure 3 As shown in the figure, the schematic diagram of the specimen structure with a microstructure protrusion height of 0.05 mm is shown in Figure 3 As shown, the design of each group of specimens is:

[0064] Blank control group: smooth disc, without any treatment;

[0065] Positive control group: smooth disk, vertically sprayed with Al2O3 with a particle size of 160 μm at a pressure of 0.2 MPa and a distance of 10 mm. 2 O 3 Particles, injection time is 10s;

[0066] Experimental group 1: microstructures with a protrusion ratio of 30% and a protrusion height of 0.05 mm were added to the smooth disk;

[0067] Experimental group 2: microstructures with a protrusion ratio of 30% and a protrusion height of 0.10 mm were added to the smooth disk;

[0068] Experimental group 3: microstructures with a protrusion ratio of 50% and a protrusion height of 0.05 mm were added to the smooth disk;

[0069] Experimental group 4: microstructures with a protrusion ratio of 50% and a protrusion height of 0.10 mm were added to the smooth disk;

[0070] Experimental group 5: microstructures with a protrusion ratio of 70% and a protrusion height of 0.05 mm were added to the smooth disk;

[0071] Experimental group 6: A microstructure with a protrusion ratio of 70% and a protrusion height of 0.10 mm was added to the smooth disk.

[0072] Using 3D design software, the surface of the design model of the smooth disk was divided into vertices with an interval of 0.01 mm, all vertices of the surface were selected, and 30% to 70% of the vertices were selected using a random algorithm in 3ds Max 2023 (Autodesk, USA) software, stretched 0.05 mm to 0.1 mm in a direction perpendicular to the surface, and then turbo smoothed to obtain the CAD design file of the restoration. The test piece was printed using a 3D printer.

[0073] 1.3 Resin column preparation

[0074] Kuraray AP-X light-curing composite resin (Kuraray, Japan, AG0151) was placed in a mold with an inner diameter of 14 mm and a height of 2 mm, and light-cured for 40 seconds according to the instructions to obtain a resin column used for shear bonding test.

[0075] 1.3 Specimen bonding:

[0076] The resin columns obtained above were bonded to each group of zirconia discs using Kuraray Fil SAC composite resin adhesive (Kuraray, Japan, 1S0278). After light curing for 40 seconds according to the adhesive instructions, the adhesive was allowed to stand at room temperature for 30 minutes and then stored in deionized water at 37°C for 24 hours.

[0077] 1.4 Shear adhesion test:

[0078] The shear bonding test was performed on each group of specimens after bonding using an INSTRON 5969 electronic universal material testing machine (INSTRON, USA). Figure 2As shown, the shear blade moves uniformly downward at a speed of 1 mm / min parallel to the zirconia-resin bonding interface until the zirconia disk and the resin column are completely separated. The loading force at this time is recorded as F, and the area of ​​the bonding interface is recorded as S. The shear bonding strength of each specimen is calculated to be P=F / S.

[0079] The experimental results are shown in Table 1. When the protrusion ratio is not less than 30% and the protrusion height is not less than 0.05 mm, the shear bonding strength of the specimen is significantly better than that of the traditional sandblasting group and the smooth group.

[0080] Table 1:

[0081] Grouping deal with Shear bond strength (MPa) Blank control group smooth <![CDATA[2.15±0.427 a ]]> Positive control group Sandblasting <![CDATA[2.72±0.908 a <!-- 5 -->]]> Experimental Group 1 30%, 0.05mm <![CDATA[3.80±0.562 b ]]> Experimental Group 2 30%, 0.10mm <![CDATA[5.17±0.706 c ]]> Experimental Group 3 50%, 0.05mm <![CDATA[4.34±0.779 b,c ]]> Experimental Group 4 50%, 0.10mm <![CDATA[5.33±0.732 c ]]> Experimental Group 5 70%, 0.05mm <![CDATA[4.84±0.341 c ]]> Experimental Group 6 70%, 0.10mm <![CDATA[5.13±0.309 c ]]>

[0082] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine different embodiments or examples described in this specification and the features of different embodiments or examples, unless they are contradictory.

[0083] Although the embodiments of the present invention have been shown and described above, it is to be understood that the above embodiments are exemplary and are not to be construed as limitations of the present invention. A person skilled in the art may change, modify, replace and vary the above embodiments within the scope of the present invention.

Claims

1. A tooth restoration, characterized in that: include: A base layer (101), wherein the base layer (101) has a plurality of protrusion structures (1012) that are inclined and / or perpendicular to an inner surface (1011) of the base layer.

2. The dental restoration according to claim 1, characterized in that The base layer (101) has a plurality of protrusion structures (1012) perpendicular to the inner surface (1011) of the base layer; Optionally, the ratio of the total contact area of ​​the plurality of protrusion structures (1012) and the inner surface (1011) of the base layer to the area of ​​the inner surface (1011) of the base layer is 30% to 70%; Preferably, the total contact area of ​​the plurality of protrusion structures with the inner surface of the base layer accounts for 50% of the inner surface area of ​​the base layer; Optionally, the vertical distance between the protruding structure (1012) and the inner surface (1011) of the base layer is 0.05-0.1 mm.

3. The dental restoration according to claim 1, characterized in that The material of the base layer (101) and / or the protruding structure (1012) is at least one of zirconium oxide, metal titanium, titanium alloy, cobalt-chromium alloy and stainless steel.

4. The dental restoration according to claim 1, characterized in that The restoration is bonded to the abutment by an adhesive; Optionally, the inner surface (1011) of the base layer is bonded to the abutment tooth by an adhesive; Optionally, the adhesive fills the gaps between the plurality of protruding structures (1012) and the gaps between the restoration and the abutment; Optionally, the restoration further comprises a base layer outer surface (1013), and the dental restoration contacts the oral cavity through the base layer outer surface (1013).

5. A method for manufacturing a dental restoration, characterized in that: include: A base layer is obtained, wherein the base layer has a plurality of protrusion structures inclined and / or perpendicular to the inner surface of the base layer.

6. The method according to claim 5, characterized in that The base layer (101) has a plurality of protrusion structures (1012) perpendicular to the inner surface (1011) of the base layer; Optionally, the ratio of the total contact area of ​​the plurality of protrusion structures with the inner surface of the base layer to the inner surface area of ​​the base layer is 30% to 70%; Preferably, the total contact area of ​​the plurality of protrusion structures with the inner surface of the base layer accounts for 50% of the inner surface area of ​​the base layer; Optionally, the vertical distance between the protruding structure and the inner surface of the base layer is 0.05-0.1 mm.

7. The method according to claim 5, characterized in that The material of the restoration is at least one of zirconium oxide, titanium, titanium alloy, cobalt-chromium alloy and stainless steel; Optionally, the restoration is bonded to the abutment by an adhesive; Optionally, the inner surface of the base layer is bonded to the abutment tooth via an adhesive; Optionally, the adhesive fills the gaps between the plurality of protruding structures and the gaps between the restoration and the abutment; Optionally, the restoration further comprises a base layer outer surface, and the dental restoration contacts the oral cavity through the base layer outer surface.

8. The method according to claim 5, characterized in that The method comprises: before obtaining the restoration, obtaining restoration data of the tooth to be restored in advance, and designing the restoration based on the restoration data; Optionally, the restoration data is obtained by: preparing the tooth to be restored, and performing a three-dimensional scan of the prepared tooth by an intraoral scanning device; Optionally, the restoration data includes at least one of the following: morphology, position and occlusal relationship.

9. The method according to claim 8, characterized in that The restoration design is performed by three-dimensional design software; Optionally, the restoration design includes: based on the position, morphology, and occlusal relationship restoration data of the tooth to be restored, dividing the inner surface of the base layer into a number of triangular facets according to a threshold value, selecting all vertices of the triangular facets, randomly selecting 30% to 70% of the vertices therein, stretching them by 0.05 mm to 0.1 mm along the normal direction, and then turbo-smoothing them to obtain a design file of the restoration; Optionally, the threshold value is 0.01 to 0.1 mm, preferably 0.01 mm; Preferably, the three-dimensional design software includes at least one of the following: CAD, 3ds Max and SolidWorks.

10. The method according to claim 5, characterized in that The dental restoration is obtained by printing using a 3D printer based on the restoration design file.

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