Integrated image measurement system and method for anterior segment and posterior segment

Abstract

The invention discloses an integrated image measurement system and method for anterior and posterior eye segments, a sweep-frequency light source is used for emitting near-infrared light, a coupler is used for dividing the received near-infrared light into two light beams according to a proportion, the first light beam is transmitted to a reference arm, the second light beam is transmitted to a sample arm, and the sample arm is used for measuring the anterior and posterior eye segments. The sample arm is used for obtaining a Bessel beam after the second light beam passes through the diffractive optical element and focusing the Bessel beam on the eye to generate a backscattering beam after the Bessel beam enters the first 4f combined lens and the second 4f combined lens, and the balance detector is used for interfering the backscattering beam with the light beam output by the reference arm. The data acquisition card is used for converting the electric signal into a digital signal, and the computer is used for obtaining an integrated image of the anterior segment and the posterior segment of the eye based on the digital signal. According to the invention, in a large focal depth range, the anterior segment and the posterior segment can be clearly imaged in the same time period interval.

Description

Technical Field

[0001] The present invention relates to the field of optical imaging technology, and in particular to, but not limited to, an integrated image measurement system and method for anterior and posterior ocular segments. Background Art

[0002] Eye screening ophthalmometers and ophthalmic biometric multi-parameter measuring instruments are indispensable equipment for ophthalmic examination and diagnosis, used to evaluate multiple parameters such as the anterior segment refraction, corneal curvature, anterior segment structure, posterior segment tissue structure, etc. These parameters are crucial for accurate diagnosis of eye diseases such as myopia, hyperopia, astigmatism, cataracts, glaucoma, macular degeneration, retinal detachment, etc.

[0003] In the related art, by adjusting the switching switch, Flip Mirrors can realize the on and off states, and each state realizes an imaging position. For example, when Flip Mirrors are not in use, fundus focusing imaging can be realized, and when Flip Mirrors are used, imaging of the anterior segment of the eye can be realized, or coherent imaging of the anterior segment of the eye and retina can be realized by scanning the source optical coherence tomography at the same time, and imaging of the anterior and posterior segments of the eye can be realized by the spectroscopic effect of PBS. However, the multi-optical path system needs to quickly switch the optical path to realize imaging at different positions of the eyeball. If the switching mechanism (such as the flip mirror) is not fast enough, the imaging efficiency will be reduced, which is not suitable for applications requiring high frame rates. In addition, these components may need maintenance or replacement after long-term use. Secondly, the system uses an optical path, a scanner and multiple high-precision optical components, and the overall manufacturing cost is relatively high, which limits the applicability of the system in low-cost applications. In addition, there are multiple active components in the system, which increase the mechanical complexity and the possibility of failure. In such a complex optical path, the stability of the phase may be difficult to maintain. A slight mechanical vibration or temperature change may cause changes in the optical path and phase, thereby affecting the quality of the interference signal.

[0004] Therefore, how to achieve rapid and clear imaging of the anterior and posterior ocular segments within the same time period within a large focal depth range has become an urgent problem to be solved. Summary of the invention

[0005] In view of this, an embodiment of the present invention provides an integrated image measurement system for the anterior and posterior segments of the eye, which at least solves the problem that the related art cannot efficiently and clearly image the integrated image of the anterior and posterior segments of the eye.

[0006] According to a first aspect of an embodiment of the present invention, there is provided an integrated image measurement system for anterior and posterior segments of an eye, comprising: a swept frequency light source, a balanced detector, a data acquisition card, a coupler, a reference arm, a sample arm and a computer, wherein the sample arm comprises a first 4f combined lens, a second 4f combined lens and a diffractive optical element;

[0007] The swept frequency light source is used to emit near-infrared light;

[0008] The coupler is used to divide the received near-infrared light into two beams according to a ratio, wherein the first beam is delivered to the reference arm, and the second beam is delivered to the sample arm;

[0009] The sample arm is used to obtain a Bessel beam after the second light beam passes through the diffractive optical element, and to focus the Bessel beam on the eye to generate a backscattered beam after the Bessel beam enters the first 4f combination lens and the second 4f combination lens;

[0010] The balanced detector is used to interfere the backscattered light beam with the light beam output by the reference arm and convert the interfered light beam into an electrical signal;

[0011] The data acquisition card is used to convert the electrical signal into a digital signal;

[0012] The computer is used to obtain an integrated image of the anterior and posterior segments of the eye based on the digital signal.

[0013] In a second aspect, an embodiment of the present invention provides an integrated image measurement method for the anterior and posterior segments of an eye, which is applied to an integrated image measurement system for the anterior and posterior segments of an eye as described in the first aspect, comprising:

[0014] The acquired near-infrared light is divided into a first light beam and a second light beam according to a ratio;

[0015] Passing the first light beam through a reference arm in an integrated image measurement system to obtain an output light beam, and passing the second light beam through a diffractive optical element in the integrated image measurement system to obtain a Bessel light beam;

[0016] Focusing the Bessel beam on the eye after passing through the first 4f combined lens and the second 4f combined lens in the integrated image measurement system to generate a backscattered beam;

[0017] interfering the output light beam with the backscattered light beam to obtain an interfered light beam, and converting the interfered light beam into an electrical signal;

[0018] The electrical signal is converted into a digital signal, and an integrated image of the anterior and posterior segments of the eye is acquired based on the digital signal.

[0019] The scheme provided by the embodiment of the present invention, the integrated image measurement system of the anterior and posterior segments of the eye includes a swept light source, a balanced detector, a data acquisition card, a coupler, a reference arm, a sample arm and a computer, wherein the sample arm includes a first 4f combined lens, a second 4f combined lens and a diffractive optical element; a swept light source for emitting near-infrared light; a coupler for dividing the received near-infrared light into two beams in proportion, wherein the first beam is delivered to the reference arm and the second beam is delivered to the sample arm; the sample arm is for obtaining a Bessel beam after the second beam passes through the diffractive optical element, and after the Bessel beam enters the first 4f combined lens and the second 4f combined lens, it is focused on the eye to generate a backscattered beam; a balanced detector for interfering the backscattered beam with the beam output by the reference arm, and converting the interfered beam into an electrical signal; a data acquisition card for converting the electrical signal into a digital signal; and a computer for obtaining an integrated image of the anterior and posterior segments of the eye based on the digital signal. The integrated image measurement system of the anterior and posterior segments of the eye has a simple structure and requires few devices. The use of diffractive optical elements for beam shaping can achieve clear focused imaging within a long focal depth range, and by introducing phase adjustment, the desired extended focal depth length can be achieved. Within a large focal depth range, the lateral imaging resolution is greatly improved compared to the traditional Gaussian beam imaging system. Within the extended focal depth range, the anterior and posterior segments of the eye can be imaged within the same time period interval. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for describing the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative work, among which:

[0021] Figure 1 The architecture of an integrated image measurement system for the anterior and posterior segments of the eye provided by an embodiment of the present invention Figure 1 ;

[0022] Figure 2 The architecture of an integrated image measurement system for the anterior and posterior segments of the eye provided by an embodiment of the present invention Figure 2 ;

[0023] Figure 3 The architecture of an integrated image measurement system for the anterior and posterior segments of the eye provided by an embodiment of the present invention Figure 3 ;

[0024] Figure 4 The architecture of an integrated image measurement system for the anterior and posterior segments of the eye provided by an embodiment of the present invention Figure 4 ;

[0025] Figure 5A schematic flow chart of a method for integrated image measurement of the anterior and posterior segments of the eye provided by an embodiment of the present invention;

[0026] Figure 6 A schematic diagram of the effect of a diffractive optical element provided by an embodiment of the present invention. DETAILED DESCRIPTION

[0027] In order to make the purpose, technical scheme and advantages of the embodiments of the present invention clearer, the technical scheme in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, rather than all the embodiments. The following embodiments are used to illustrate the present invention, but are not used to limit the scope of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0028] In the following description, reference is made to “some embodiments”, which describe a subset of all possible embodiments, but it will be understood that “some embodiments” may be the same subset or different subsets of all possible embodiments and may be combined with each other without conflict.

[0029] It should be pointed out that the terms "first\second\third" involved in the embodiments of the present invention are only used to distinguish similar objects and do not represent a specific ordering of the objects. It can be understood that "first\second\third" can be interchanged in a specific order or sequence where permitted, so that the embodiments of the present invention described here can be implemented in an order other than that illustrated or described here.

[0030] It will be understood by those skilled in the art that, unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as those generally understood by those skilled in the art in the field to which the embodiments of the present invention belong. It should also be understood that terms such as those defined in general dictionaries should be understood to have meanings consistent with those in the context of the prior art, and will not be interpreted with idealized or overly formal meanings unless specifically defined as here.

[0031] like Figure 1 As shown, Figure 1 The architecture of an integrated image measurement system for the anterior and posterior segments of the eye provided by an embodiment of the present invention Figure 1The integrated image measurement system 100 includes a swept-frequency light source 1, a balanced detector 2, a data acquisition card 3, a coupler 4, a reference arm 5, a sample arm 6 and a computer 7, wherein the sample arm 6 includes a first 4f combined lens 8, a second 4f combined lens 9 and a diffractive optical element 10. The swept-frequency light source 1 is used to emit near-infrared light with a wavelength of 1310 nanometers, a bandwidth of 100 nanometers and an incident spot diameter of 3.0 millimeters;

[0032] A coupler 4 is used to divide the received near-infrared light into two beams according to a ratio, wherein the first beam is transmitted to the reference arm 5 and the second beam is transmitted to the sample arm;

[0033] The sample arm 6 is used to obtain a Bessel beam after the second light beam passes through the diffractive optical element 10, and the Bessel beam is focused on the eye to generate a backscattered beam after entering the first 4f combination lens 8 and the second 4f combination lens 9;

[0034] A balanced detector 2, used for interfering the backscattered light beam with the light beam output by the reference arm, and converting the interfered light beam into an electrical signal;

[0035] A data acquisition card 3, used for converting electrical signals into digital signals;

[0036] The computer 7 is used to obtain an integrated image of the anterior and posterior segments of the eye based on the digital signal.

[0037] Furthermore, the grating period of the diffractive optical element is d=8 μm, and the diffraction grating equation is formula (1):

[0038]

[0039] In the above formula, λ is the wavelength of the first beam of light, d is the grating constant, that is, the distance between two adjacent lines, m is the diffraction order (usually the first order, m=1), and θ is the diffraction angle.

[0040] The depth of focus (non-diffraction distance) DoF of the Bessel beam is given by formula (2):

[0041]

[0042] When the approximation is: tanθ≈sinθ at a small angle, formula (3) is obtained according to formula (1) and formula (2):

[0043]

[0044] Among them, the incident spot radius So the focal depth of the Bessel beam is given by formula (4):

[0045]

[0046] In the above formula (4), D is the incident light spot diameter, which determines the size of the incident light beam.

[0047] Furthermore, the first 4f combined lens and the second 4f combined lens will change the size and divergence angle of the second light beam. For a linear optical system, the magnification M of the first 4f combined lens and the second 4f combined lens can be defined as:

[0048]

[0049] In the above formula (5), f1 and f2 are the focal lengths of the first 4f combined lens and the second 4f combined lens respectively.

[0050] After the incident spot diameter D in formula (4) is enlarged, D'=M·D, and the diffraction angle changes: Approximate formula (5) and formula (6) at small angles:

[0051]

[0052] For small angles, θ≈mλ / d, the new focal depth of the Bessel beam can be expressed as formula (7):

[0053]

[0054] The final focal depth of the Bessel beam is obtained by formula (5) and formula (7) as formula (8):

[0055]

[0056] For example, to achieve a depth of focus DoF' = 24mm under the conditions of λ = 1310nm, m = 1, and D = 3mm, it is necessary to select appropriate parameters, including magnification M, grating period d, and lens focal length. Period d = 8μm, M ≈ 1.619, f1 = 50mm, f2 = M × f1 = 1.619 × 50mm ≈ 80.95mm, θ = arcsin (0.16375) ≈ 9.43, and DoF' ≈ 24mm is obtained. Among them, the grating period d, DoF' and f1 are known, and they are substituted into the above formula to obtain values ​​such as f2 and θ.

[0057] It can be understood that in an embodiment of the present invention, the integrated image measurement system of the anterior and posterior segments of the eye includes a swept light source, a balanced detector, a data acquisition card, a coupler, a reference arm, a sample arm and a computer, wherein the sample arm includes a first 4f combined lens, a second 4f combined lens and a diffractive optical element; a swept light source for emitting near-infrared light; a coupler for dividing the received near-infrared light into two beams in proportion, wherein the first beam is delivered to the reference arm and the second beam is delivered to the sample arm; the sample arm is used to obtain a Bessel beam after the second beam passes through the diffractive optical element, and after the Bessel beam enters the first 4f combined lens and the second 4f combined lens, it is focused on the eye to generate a backscattered beam; a balanced detector is used to interfere the backscattered beam with the beam output by the reference arm, and convert the interfered beam into an electrical signal; a data acquisition card is used to convert the electrical signal into a digital signal; and a computer is used to obtain an integrated image of the anterior and posterior segments of the eye based on the digital signal. The integrated image measurement system of the anterior and posterior segments of the eye has a simple structure and requires few devices. The use of diffractive optical elements for beam shaping can achieve clear focused imaging within a long focal depth range, and by introducing phase adjustment, the desired extended focal depth length can be achieved. Within a large focal depth range, the lateral imaging resolution is greatly improved compared to the traditional Gaussian beam imaging system. Within the extended focal depth range, the anterior and posterior segments of the eye can be imaged within the same time period interval.

[0058] In some embodiments of the present invention, Figure 2 As shown, Figure 2 The architecture of an integrated image measurement system for the anterior and posterior segments of the eye provided by an embodiment of the present invention Figure 2 ,exist Figure 2 In the figure, the reference arm 5 includes a first collimating lens 51, a rotating prism 52 and a reflector 53. The first beam of light passes through the first collimating lens 51, the rotating prism 52 and the reflector 53 of the reference arm 5 in sequence; the light emitted by the reflector 53 passes through the rotating prism 52 and the first collimating lens 51 in sequence to the coupler 4.

[0059] In some embodiments of the present invention, Figure 3 As shown, Figure 3 The architecture of an integrated image measurement system for the anterior and posterior segments of the eye provided by an embodiment of the present invention Figure 3 .exist Figure 3 In the embodiment, the sample arm 6 further includes a second collimating lens 61. The second light beam is collimated by the second collimating lens 61. Then, the parallel light enters the diffractive optical element 10 to generate a diffracted light beam, which is then shaped to obtain a Bessel light beam.

[0060] In some embodiments of the present invention, Figure 4 As shown, Figure 4The architecture of an integrated image measurement system for the anterior and posterior segments of the eye provided by an embodiment of the present invention Figure 4 .exist Figure 4 In the figure, the sample arm 6 also includes a deflectable reflector 62 and an imaging objective lens 63 (L6 in the figure), the first 4f combined lens 8 is composed of a first lens 81 (L3 in the figure) and a second lens 82 (L4 in the figure), and the second 4f combined lens 9 is composed of a second lens 82 and a third lens 91 (L5 in the figure). The Bessel beam enters the focal plane of the first lens 81 and the second lens 82 to generate a specific beam, and the specific beam enters the third lens 91, the deflectable reflector 62 and the imaging objective lens 63 in sequence and then focuses on the eye (the sample in the figure) to generate a backscattered beam, and the backscattered beam enters the imaging objective lens 63, the deflectable reflector 62, the third lens 91, the second lens 82, the first lens 81, the diffractive optical element 10, the second collimating lens 61 (L2 in the figure) and the coupler 4 again. The coupler 4 transmits the received backscattered beam and the beam output by the reference arm 5 to the balanced detector 2, wherein L1 is the first collimating lens 51.

[0061] In an embodiment of the present invention, Figure 5 As shown, Figure 5 A schematic flow chart of an integrated image measurement method for the anterior and posterior segments of the eye provided by an embodiment of the present invention. The integrated image measurement method for the anterior and posterior segments of the eye can be applied to the integrated image measurement system for the anterior and posterior segments of the eye, which is described by the following steps.

[0062] S101 , dividing the acquired near-infrared light into a first light beam and a second light beam according to a ratio.

[0063] S102 , obtaining an output beam after the first light beam passes through a reference arm in the integrated image measurement system, and obtaining a Bessel light beam after the second light beam passes through a diffractive optical element in the integrated image measurement system.

[0064] In an embodiment of the present invention, near-infrared light with a wavelength of 1310 nanometers, a bandwidth of 100 nanometers, and an incident spot diameter of 3.0 millimeters emitted by a swept light source in an integrated image measurement system is obtained, and the obtained near-infrared light is divided into a first beam and a second beam in proportion by a coupler. The first beam is passed through a reference arm in the integrated image measurement system to obtain an output beam. The second beam is collimated by a second collimating lens, and then the parallel beam is passed through a diffractive optical element to generate a diffracted beam, which is shaped to obtain a Bessel beam.

[0065] S103, focusing the Bessel light beam on the eye after passing through the first 4f combination lens and the second 4f combination lens in the integrated image measurement system to generate a backscattered light beam.

[0066] In an embodiment of the present invention, the first lens and the second lens form a first 4f combination lens, and the second lens and the third lens form a second 4f combination lens. The Bessel light beam passes through the first lens, the second lens, and the third lens in the integrated image measurement system, and then passes through a deflectable reflector and an imaging objective lens and is focused on the eye to generate a backscattered light beam.

[0067] S104, interfering the output light beam with the backscattered light beam to obtain an interfered light beam, and converting the interfered light beam into an electrical signal.

[0068] In an embodiment of the present invention, the output light beam and the backscattered light beam interfere with each other in a balanced detector of the integrated image measurement system to obtain an interfered light beam, and the interfered light beam is further converted into an electrical signal by the balanced detector.

[0069] S105, converting the electrical signal into a digital signal, and acquiring an integrated image of the anterior and posterior segments of the eye based on the digital signal.

[0070] In an embodiment of the present invention, the output light beam and the backscattered light beam interfere with each other in a balanced detector of the integrated image measurement system to obtain an interfered light beam, which is further converted into an electrical signal by the balanced detector. A data acquisition card in the integrated image measurement system converts the electrical signal into a digital signal and outputs it to a computer, where a post-algorithm solution is performed to obtain an integrated image of the anterior and posterior segments of the eye.

[0071] It can be understood that in an embodiment of the present invention, the acquired near-infrared light is divided into a first beam of light and a second beam of light in proportion, the first beam is passed through the reference arm in the integrated image measurement system to obtain an output beam, and the second beam is passed through the diffractive optical element in the integrated image measurement system to obtain a Bessel beam, the Bessel beam is focused on the eye after passing through the first 4f combined lens and the second 4f combined lens in the integrated image measurement system to generate a backscattered beam, the output beam and the backscattered beam are interfered to obtain an interfered beam, and the interfered beam is converted into an electrical signal, the electrical signal is converted into a digital signal, and an integrated image of the anterior and posterior segments of the eye is obtained based on the digital signal. In this method, the desired purpose of extending the focal depth length is achieved by introducing phase adjustment. In a large focal depth range, the lateral imaging resolution is greatly improved compared to the traditional Gaussian beam imaging system. In the extended focal depth range, the anterior segment of the eye and the posterior segment of the eye can be imaged within the same time period interval. Using a new phase control method, a beam shaping method using a diffractive optical element can be used to clearly focus and image within a long focal depth range.

[0072] In some embodiments of the present invention, S10 to S11 are also included before S102, which is explained by the following steps.

[0073] S10, calculating the phase distribution based on the preset target light field and the light field distribution formula at the preset focal plane, and obtaining the design result of the microstructure on the surface of the initial diffractive optical element based on the phase distribution.

[0074] In some embodiments of the present invention, the preset target light field is a specific light field distribution (e.g., uniform distribution, specific pattern, etc.) obtained on the focal plane. The light field at the focal plane refers to the light intensity and phase distribution formed on the focal plane after the light passes through an optical system (such as a lens, a lens group, or other focusing elements). Simply put, it describes the light characteristics of each point on the focal plane, including brightness (or energy density), color (wavelength), and phase information of the light wave. The phase distribution is calculated by using the preset target light field and the preset light field distribution formula at the focal plane. After the phase distribution of the initial diffractive optical element is designed, the design result of the microstructure on the surface of the initial diffractive optical element is obtained. Among them, the light field distribution formula at the preset focal plane is as follows (9):

[0075]

[0076] In the above formula, t is the transmittance on the diffractive optical element, f is the power distribution of the incident light field, ρ is the radial coordinate at the focal plane behind the focusing lens, J0 is the zero-order Bessel function, f0 is the focal length of the focusing lens, λ0 is the central wavelength of the incident light, E is the electric field distribution, γ is the position of a point on the diffractive optical element, and r is the radius of the diffractive optical element.

[0077] S11. Coating a photoresist on the base material of the initial diffractive optical element, etching the photoresist according to the design result, and removing the photoresist or cleaning the surface after the etching is completed to obtain a diffractive optical element with a microstructure.

[0078] In some embodiments of the present invention, a photoresist is coated on a base material (such as glass or quartz) of an initial diffractive optical element, and etching is performed according to a design result using processes such as photolithography or electron beam etching to form a desired microstructure, and after etching is completed, the photoresist is removed or the surface is cleaned to obtain a diffractive optical element with a microstructure.

[0079] When a Gaussian beam or a collimated beam passes through a designed diffractive optical element, the phase of the beam will be modulated into the distribution required by the Bessel beam. In this way, through diffraction and interference, a ring-shaped light field distribution is formed in the far field of the diffractive optical element, generating a Bessel beam with a long focal depth and self-reconstruction characteristics.

[0080] In some embodiments of the present invention, Figure 6 As shown, Figure 6 A schematic diagram of the effect of a diffractive optical element provided by an embodiment of the present invention. Figure 6 In, rx , r y represents the rectangular coordinates in the x and y directions, r0 is the diameter of the black circle, and T is the distance between black and white.

[0081] It should be noted that, in the embodiment of the present invention, if the above-mentioned integrated image measurement method of the anterior and posterior segments of the eye is implemented in the form of a software function module and sold or used as an independent product, it can also be stored in a computer-readable storage medium. Based on this understanding, the technical solution of the embodiment of the present invention can be essentially or partly reflected in the form of a software product that contributes to the relevant technology. The computer software product is stored in a storage medium, including several instructions for enabling an electronic device to execute all or part of the methods described in each embodiment of the present invention. The aforementioned storage medium includes: various media that can store program codes, such as a U disk, a mobile hard disk, a read-only memory (ROM), a magnetic disk or an optical disk. In this way, the embodiment of the present invention is not limited to any specific combination of hardware and software.

[0082] Correspondingly, an embodiment of the present invention provides a computer-readable storage medium having a computer program stored thereon, and when the computer program is executed by a processor, the steps in the one-piece image measurement method for the anterior and posterior segments of the eye described in any of the above embodiments are implemented. Correspondingly, an embodiment of the present invention also provides a computer program product, and when the computer program product is executed by a processor of an electronic device, it is used to implement the steps in the one-piece image measurement method for the anterior and posterior segments of the eye described in any of the above embodiments.

[0083] It should be understood that "one embodiment" or "an embodiment" mentioned throughout the specification means that specific features, structures or characteristics related to the embodiment are included in at least one embodiment of the present invention. Therefore, "in one embodiment" or "in an embodiment" appearing throughout the specification does not necessarily refer to the same embodiment. In addition, these specific features, structures or characteristics can be combined in one or more embodiments in any suitable manner. It should be understood that in various embodiments of the present invention, the size of the serial number of the above-mentioned processes does not mean the order of execution. The execution order of each process should be determined by its function and internal logic, and should not constitute any limitation on the implementation process of the embodiment of the present invention. The serial numbers of the above-mentioned embodiments of the present invention are only for description and do not represent the advantages and disadvantages of the embodiments.

[0084] It should be noted that, in this article, the terms "include", "comprises" or any other variations thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, an element defined by the sentence "comprises a ..." does not exclude the existence of other identical elements in the process, method, article or device including the element.

[0085] In the several embodiments provided by the present invention, it should be understood that the disclosed devices and methods can be implemented in other ways. The device embodiments described above are only schematic. For example, the division of the units is only a logical function division. There may be other division methods in actual implementation, such as: multiple units or components can be combined, or can be integrated into another system, or some features can be ignored or not executed. In addition, the coupling, direct coupling, or communication connection between the components shown or discussed can be through some interfaces, and the indirect coupling or communication connection of the devices or units can be electrical, mechanical or other forms.

[0086] The units described above as separate components may or may not be physically separated, and the components displayed as units may or may not be physical units; they may be located in one place or distributed on multiple network units; some or all of the units may be selected according to actual needs to achieve the purpose of the embodiment of the present invention.

[0087] In addition, all functional units in the embodiments of the present invention may be integrated into one processing unit, or each unit may be separately used as a unit, or two or more units may be integrated into one unit; the above-mentioned integrated units may be implemented in the form of hardware or in the form of hardware plus software functional units.

[0088] The methods disclosed in the several method embodiments provided by the present invention can be arbitrarily combined without conflict to obtain new method embodiments.

[0089] The features disclosed in several method or device embodiments provided by the present invention can be arbitrarily combined without conflict to obtain new method embodiments or device embodiments.

[0090] The above is only an embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art can easily think of changes or substitutions within the technical scope disclosed by the present invention, which should be included in the protection scope of the present invention. Therefore, the protection scope of the present invention should be based on the protection scope of the claims.

Claims

1. An integrated image measurement system for the anterior and posterior segments of the eye, characterized in that: It includes a frequency sweeping light source, a balanced detector, a data acquisition card, a coupler, a reference arm, a sample arm and a computer, wherein the sample arm includes a first 4f combined lens, a second 4f combined lens and a diffractive optical element; The swept frequency light source is used to emit near-infrared light; The coupler is used to divide the received near-infrared light into two beams according to a ratio, wherein the first beam is transmitted to the reference arm, and the second beam is transmitted to the sample arm; The sample arm is used to obtain a Bessel beam after the second light beam passes through the diffractive optical element, and to focus the Bessel beam on the eye to generate a backscattered beam after the Bessel beam enters the first 4f combination lens and the second 4f combination lens; The balanced detector is used to interfere the backscattered light beam with the light beam output by the reference arm and convert the interfered light beam into an electrical signal; The data acquisition card is used to convert the electrical signal into a digital signal; The computer is used to obtain an integrated image of the anterior and posterior segments of the eye based on the digital signal.

2. The integrated image measurement system according to claim 1, characterized in that: The swept-frequency light source is used to emit the near-infrared light with a wavelength of 1310 nanometers, a bandwidth of 100 nanometers, and an incident light spot diameter of 3.0 millimeters.

3. The integrated image measurement system according to claim 1, characterized in that: The reference arm includes a first collimating lens, a rotating prism and a reflector; the first beam of light passes through the first collimating lens, the rotating prism and the reflector of the reference arm in sequence; the light emitted by the reflector then passes through the rotating prism and the first collimating lens in sequence to the coupler.

4. The integrated image measurement system according to claim 1, characterized in that: The sample arm also includes a second collimating lens. The second beam of light generates a diffracted light beam after passing through the second collimating lens and the diffractive optical element, and the diffracted light beam is shaped to obtain the Bessel light beam.

5. The integrated image measurement system according to claim 4, wherein the sample arm further comprises a deflectable reflector and an imaging objective lens; the first 4f combined lens is composed of a first lens and a second lens, the second 4f combined lens is composed of the second lens and a third lens, the Bessel light beam enters the focal plane after the first lens and the second lens to generate a specific light beam, the specific light beam enters the third lens, the deflectable reflector and the imaging objective lens in sequence and then is focused on the eye to generate the backscattered light beam; the backscattered light beam enters the imaging objective lens, the deflectable reflector, the third lens, the second lens, the first lens, the diffractive optical element, the second collimating lens and the coupler again.

6. The integrated image measurement system according to claim 5, characterized in that: The coupler is also used to transmit the backscattered light beam and the light beam output by the reference arm to the balanced detector.

7. A method for integrated image measurement of the anterior and posterior segments of the eye, characterized in that: The method applied to the integrated image measurement system for the anterior and posterior segments of the eye as claimed in any one of claims 1 to 6 comprises: The acquired near-infrared light is divided into a first light beam and a second light beam according to a ratio; Passing the first light beam through a reference arm in an integrated image measurement system to obtain an output light beam, and passing the second light beam through a diffractive optical element in the integrated image measurement system to obtain a Bessel light beam; Focusing the Bessel beam on the eye after passing through the first 4f combined lens and the second 4f combined lens in the integrated image measurement system to generate a backscattered beam; interfering the output light beam with the backscattered light beam to obtain an interfered light beam, and converting the interfered light beam into an electrical signal; The electrical signal is converted into a digital signal, and an integrated image of the anterior and posterior segments of the eye is acquired based on the digital signal.

8. The method according to claim 7, characterized in that Before the first light beam is passed through a reference arm in the integrated image measurement system to obtain an output light beam, and the second light beam is passed through a diffractive optical element in the integrated image measurement system to obtain a Bessel light beam, the method further includes: Calculating a phase distribution based on a preset target light field and a preset light field distribution formula at a focal plane, and obtaining a design result of a microstructure on the surface of an initial diffractive optical element based on the phase distribution; A photoresist is coated on the base material of the initial diffractive optical element, etching is performed on the photoresist according to the design result, and after the etching is completed, the photoresist is removed or the surface is cleaned to obtain the diffractive optical element with a microstructure.

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