Hepatocyte sample collecting device

By designing a hepatocyte sample collection device including a needle, a biopsy cylinder and a collection mechanism, the problems of low purity and insufficient integrity of the sample in the prior art are solved, and high purity and integrity sample collection is achieved, which is suitable for subsequent microscopic detection.

CN120189171AInactive Publication Date: 2025-06-24HEXI UNIV
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Patent Information

Application Number
CN202510546398.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-04-28
Publication Date
2025-06-24
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

Existing hepatocyte sample collection technology leads to low purity and insufficient integrity of the sample, affecting subsequent detection results.

Method used

A hepatocyte sample collection device including a needle, a biopsy cylinder, a protective traction line and a collection mechanism is designed. The front end of the biopsy barrel is equipped with soft magnetic material and ultrasonic endoscope. It is controlled to move within the blood vessels through electromagnetic navigation devices to ensure the accuracy of sample collection. The collection mechanism includes a servo motor, gear plate and gear. Through the alternating use of a rotary cutter and a circumcision knife, multi-layer sampling is achieved and the samples are kept in a normal saline environment.

Benefits of technology

It improves the purity and integrity of the sample, avoids the mixing of blood and tissue fluid, and simplifies the subsequent microscopic detection process. The sample is taken out in a complete circular sheet, suitable for direct microscopic testing.

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Abstract

The invention discloses a hepatocyte sample collection device, and relates to the technical field of medical collection, the hepatocyte sample collection device comprises a pricking needle, a biopsy cylinder, a protective pull wire and a collection mechanism; the pricking needle is used for puncturing a hepatic vein blood vessel, the biopsy cylinder enters the blood vessel through the pricking needle pipeline, a soft magnetic material and an ultrasonic endoscope are arranged in the front end of the biopsy cylinder, and the soft magnetic material is controlled by external electromagnetic navigation equipment to move in the blood vessel and finally reaches a to-be-sampled part. The ultrasonic endoscope is used for measuring the specific position of the biopsy tube in real time and transmitting image signals to an external display end, one end of the protective traction line is connected with the rear end of the biopsy tube, the other end of the protective traction line penetrates through the pricking needle and is manually controlled by medical staff, and the collecting mechanism is arranged in the biopsy tube.
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