Probe set for detecting genetic chronic granulomatosis related gene mutation, kit and application

CN120272573AActive Publication Date: 2025-07-08THE SEVENTH MEDICAL CENTER OF PLA GENERAL HOSPITAL +1
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Patent Information

Application Number
CN202510769786.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-06-10
Publication Date
2025-07-08
Estimated Expiration
2045-06-10

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Abstract

The invention provides a probe set for detecting genetic chronic granulomatosis related gene mutation, a kit and application, and relates to the technical field of molecular biology. The hereditary chronic granulomatosis related genes comprise a CYBA gene, an NCF1 gene, an NCF2 gene, a CYBB gene, a WG gene, an NCF4 gene, a CYBC1 gene, an ASAH1 gene, an RAG2 gene and an RAG1 gene. Through a targeted panel customized by the probe, major genes related to chronic granuloma can be efficiently captured, the detection efficiency and the positive rate can be greatly improved, the period is shortened, and the detection cost of genetic CGD second-generation high-throughput sequencing is reduced.
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Citation Information

Patent Citations

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