Hypotube and guidewire

Abstract

The application provides a hypotube and a guide wire. The hypotube is applied to the guide wire and comprises at least two tube segments arranged in sequence along the extension direction of the hypotube. The hypotube comprises a body part and a recess part arranged in the body part. In at least one tube segment, at least one recess part extends on the circumferential surface of the body part to form a spiral arrangement, and comprises a plurality of thread segments arranged along the extension direction of the recess part. Along the extension direction of the hypotube, the body part between adjacent thread segments forms a ring part. The rigidity of the tube segment close to the proximal end of the hypotube is greater than the rigidity of the tube segment close to the distal end of the hypotube. At least one of the pitch of the ring part and the width of the recess part is different between different tube segments; the width of the recess part is the distance between the opposite two side surfaces of the recess part in the direction perpendicular to the extension direction of the recess part. The hypotube of the application has different rigidity of each tube segment, and has good traceability and accessibility.

Description

Technical Field

[0001] This application relates to the field of medical device technology, and more specifically, to a hypotube and guidewire. Background Technology

[0002] Guidewires and other interventional medical devices typically need to have a certain degree of rigidity and flexibility to ensure good trackability and accessibility in tortuous anatomical structures, good torque transmission during delivery, and ensure that the distal end can be bent to a smaller radius to give the auxiliary blood vessel the proper curved shape.

[0003] With the development of microfabrication technology, sodium hypochlorite tubes with some recesses are used as reinforcements in guide wires. However, existing sodium hypochlorite tubes are limited by the shape of some cutting elements or recesses, and the overall stiffness of the sodium hypochlorite tube is almost uniform, making it difficult to simultaneously possess the stiffness and flexibility required in different positions. Summary of the Invention

[0004] This application addresses the shortcomings of existing methods by proposing a new type of hysteresis tube and guide wire to solve the technical problem that existing hysteresis tubes have almost uniform overall stiffness, making it difficult to simultaneously possess the required stiffness and flexibility at different locations.

[0005] In a first aspect, embodiments of this application provide a waveguide tube for use with a guidewire, comprising at least two tube segments sequentially distributed along the extension direction of the waveguide tube. The waveguide tube includes a body portion and a recess formed in the body portion.

[0006] In at least one pipe section, at least one recess extends on the circumferential surface of the body portion in a spiral distribution, including a plurality of threaded segments arranged along the extension direction of the recess.

[0007] Along the extension direction of the coastal wave tube, the body portion between adjacent threaded sections forms a ring.

[0008] The stiffness of the pipe section near the proximal end of the subwoofer tube is greater than the stiffness of the pipe section near the distal end of the subwoofer tube.

[0009] Between different pipe sections, at least one of the pitch of the annulus and the width of the recess is different; the width of the recess is the distance between two opposite sides of the recess in the direction perpendicular to the extension of the recess.

[0010] In some possible embodiments, there is one recess, which spirals around at least two pipe segments.

[0011] In some possible embodiments, the number of recesses is multiple.

[0012] In at least one pipe section, at least two recesses extend at intervals on the circumferential surface of the body to form a spiral distribution.

[0013] Along the extension direction of the concave portion, the body portion between adjacent concave portions forms a beam portion.

[0014] Between different pipe sections, at least one of the following is different: the length of the beam section and the combined length of the adjacent recess and beam section. The length of the beam section is the dimension of the beam section along the extension direction of the adjacent recess, and the length of the recess is the dimension of the recess along the extension direction of the recess.

[0015] In some possible embodiments, the stiffness of multiple segments of the thiovanic tube gradually increases from the distal end to the proximal end of the thiovanic tube.

[0016] In some possible embodiments, in at least one pipe segment, at least one recess extends circumferentially along the body portion to form an annular distribution, the annular recess being closer to the proximal end than the spiral recess.

[0017] In some possible embodiments, the central angle corresponding to the combined structure of adjacent recesses and beams is not less than 90 degrees and not greater than 115 degrees.

[0018] The pitch of the ring is not less than 0.02 mm and not more than 0.25 mm.

[0019] The width of the recess shall be no less than 0.011 mm and no more than 0.018 mm.

[0020] The central angle corresponding to the beam is no less than 8 degrees and no more than 16 degrees.

[0021] In some possible embodiments, the outer diameter of the body portion is no greater than 0.125 mm.

[0022] The central angle corresponding to the combined structure of adjacent concave and beam parts shall not be less than 70 degrees and not greater than 110 degrees.

[0023] The pitch of the ring is not less than 0.05 mm and not more than 1 mm.

[0024] The width of the recess shall be no less than 0.001 mm and no more than 0.006 mm.

[0025] The central angle corresponding to the beam is no less than 3 degrees and no more than 50 degrees.

[0026] In some possible embodiments, the width of the recess in the tube segment near the distal end of the submersible tube is greater than the width of the recess in the tube segment near the proximal end of the submersible tube.

[0027] In some possible embodiments, the length of the recess in the tube segment near the distal end of the submersible tube is greater than the length of the recess in the tube segment near the proximal end of the submersible tube.

[0028] In some possible embodiments, the pitch of the ring portion of the tube segment near the distal end of the submersible tube is smaller than the pitch of the ring portion of the tube segment near the proximal end of the submersible tube.

[0029] In some possible embodiments, the length of the beam portion in the pipe segment near the distal end of the submersible tube is less than the length of the beam portion in the pipe segment near the proximal end of the submersible tube.

[0030] In some possible embodiments, the submersible tube includes a first segment near the distal end.

[0031] In the first pipe section, along the extension direction from the distal end to the proximal end, the pitch of the ring increases sequentially according to the first design method, while the length of the beam remains unchanged.

[0032] In some possible embodiments, the submersible tube may also include a second segment that is farther from the distal end than the first segment.

[0033] In the second pipe section, along the extension direction from the distal end to the proximal end, the pitch of the ring is increased in a second design manner, and the length of the beam is increased in a third design manner.

[0034] In some possible embodiments, the submersible tube may also include a third segment that is closer to the proximal end than the second segment.

[0035] In the third pipe section, the pitch of the ring and the length of the beam remain unchanged in the direction from the distal end to the proximal end.

[0036] In some possible embodiments, the first design, the second design, and the third design each include at least one of linear, exponential, or logarithmic methods.

[0037] In some possible embodiments, the body portion includes a plurality of sub-portions divided circumferentially.

[0038] Between at least two sub-parts, at least one of the following is different: the pitch of the ring, the length of the beam, the width of the recess, and the combined length of the adjacent recess and beam.

[0039] In some possible embodiments, the width of the concave portion gradually decreases radially toward the center of the waveguide.

[0040] In some possible embodiments, an angle is formed between the two opposite sides of the recess in the direction of extension of the hyaluronic acid tube.

[0041] Secondly, embodiments of this application also provide a guide wire, including: a core wire, a coil, and any of the hysteresis tubes provided in the first aspect above.

[0042] The coil is wrapped around the outer periphery of the distal end of the core wire.

[0043] The sodium thiosulfate tube is tubular and is fitted around a portion of the coil and a portion of the core wire.

[0044] The beneficial technical effects of the technical solutions provided in this application include:

[0045] The sodium hypochlorite tube in this embodiment includes at least two segments. The segment near the proximal end of the sodium hypochlorite tube has a higher stiffness than the segment near the distal end, allowing different segments to possess their own required stiffness and flexibility, resulting in good traceability and accessibility. Furthermore, the concave shapes or patterns are more varied, facilitating the formation of a sodium hypochlorite tube that simultaneously possesses good stiffness and flexibility. This allows for balancing the complex bending stiffness, tensile strength, and torsional strength requirements of the human vascular system, while also achieving a smaller bending radius when the guidewire shape is changed as needed.

[0046] Additional aspects and advantages of this application will be set forth in part in the description which follows, and will become apparent from the description or may be learned by practice of this application. Attached Figure Description

[0047] The above and / or additional aspects and advantages of this application will become apparent and readily understood from the following description of the embodiments taken in conjunction with the accompanying drawings, wherein:

[0048] Figure 1 This is a schematic diagram of the structure of a sodium hypochlorite tube provided in an embodiment of this application;

[0049] Figure 2 This is a schematic diagram of another type of hysteresis tube provided in an embodiment of this application;

[0050] Figure 3 This is a schematic diagram of another type of sodium hypochlorite tube provided in an embodiment of this application;

[0051] Figure 4 This is a schematic diagram of another type of submersible tube provided in an embodiment of this application;

[0052] Figure 5 This is a schematic diagram of the structure of the first segment of a submersible tube provided in an embodiment of this application;

[0053] Figure 6 This is a schematic diagram of the structure of a second segment of a submersible tube provided in an embodiment of this application;

[0054] Figure 7 A schematic diagram of the structure of the third segment of a submersible tube provided in an embodiment of this application;

[0055] Figure 8 A schematic cross-sectional view of a submersible tube provided in an embodiment of this application;

[0056] Figure 9 This is a cross-sectional schematic diagram of a sodium hypochlorite tube in a bent state, provided as an embodiment of this application.

[0057] Figure label:

[0058] 110 - Body part; 111 - Ring part; 112 - Beam part; 113 - Inner side of body part 110; 114 - Outer side of body part 110; 120 - Recess;

[0059] 100 - Pipe section; 101 - First pipe section; 102 - Second pipe section; 103 - Third pipe section;

[0060] A - distal; B - proximal. Detailed Implementation

[0061] The embodiments of this application are described below with reference to the accompanying drawings. It should be understood that the embodiments described below with reference to the accompanying drawings are exemplary descriptions for explaining the technical solutions of the embodiments of this application, and do not constitute a limitation on the technical solutions of the embodiments of this application.

[0062] Those skilled in the art will understand that, unless specifically stated otherwise, the terms "described" and "the" as used herein may also include plural forms. It should be further understood that the term "comprising" as used in the specification of this application means the presence of the stated features, integers, operations, elements, and / or components, but does not exclude implementations of other features, information, data, operations, elements, components, and / or combinations thereof supported by the art. The term "and / or" as used herein refers to at least one of the items defined by the term; for example, "A and / or B" can be implemented as "A," or as "B," or as "A and B."

[0063] To make the objectives, technical solutions, and advantages of this application clearer, the embodiments of this application will be described in further detail below with reference to the accompanying drawings.

[0064] The research and development concept of this application includes: In related technologies, the sodium hypochlorite tube has a grooved section on its body to form a recess, giving it a certain degree of rigidity and flexibility. Currently, most sodium hypochlorite tubes are made by cutting the body using micro-machining techniques such as micro-saws or wire cutting to create the recess.

[0065] This micromachining technology is subject to many limitations in terms of the geometry of the concave portion, the cuttable length, and the processing speed. As a result, the hardness of the resulting sodium hypochlorite tube is basically the same in all locations, making it difficult to adjust the hardness and thus making it difficult to form a sodium hypochlorite tube that has both the required rigidity and flexibility.

[0066] The sodium hypochlorite tube and guide wire provided in this application are intended to solve the above-mentioned technical problems in related technologies.

[0067] The technical solution of this application and how it solves the above-mentioned technical problems are described in detail below with specific embodiments. It should be noted that the following embodiments can be referenced, borrowed, or combined with each other, and the same terms, similar features, and similar implementation steps in different embodiments will not be described again.

[0068] This application provides a sodium hypochlorite tube, which is used in guidewires, such as... Figure 1 As shown, the waveguide includes at least two pipe segments 100 sequentially distributed along the extension direction of the waveguide; as... Figures 2-7 As shown, the submersible tube includes a body portion 110 and a recess 120 formed in the body portion 110.

[0069] In at least one pipe section 100, at least one recess 120 extends on the circumferential surface of the body portion 110 in a spiral distribution, including a plurality of threaded segments arranged along the extension direction of the recess 120.

[0070] The direction of extension of the coastal waveguide (e.g.) Figure 5 (From left to right in the middle), the body portion 110 between adjacent threaded segments forms a ring portion 111.

[0071] The stiffness of pipe segment 100, which is closer to the proximal end B of the submersible tube, is greater than the stiffness of pipe segment 100, which is closer to the distal end A of the submersible tube.

[0072] refer to Figure 2 and Figure 4 Between different pipe sections 100, at least one of the pitch X of the ring 111 and the width D of the recess 120 is different; the width D of the recess 120 is the distance between two opposite sides of the recess 120 in the direction perpendicular to the extension of the recess 120.

[0073] The sodium hypochlorite tube in this embodiment includes at least two tube segments 100. The pitch X of the annular portion 111 or the width D of the recess 120 varies depending on the distance from the distal end A, so that each tube segment 100 has the required rigidity and flexibility. It should be noted that the pitch X of the annular portion 111 can be regarded as the width X of the body portion 110 between the threaded segments of adjacent recesses 120. The rigidity of the tube segment 100 near the proximal end B of the sodium hypochlorite tube is greater than that of the tube segment 100 near the distal end A of the sodium hypochlorite tube, so that different tube segments 100 have their own required rigidity and flexibility, and have good traceability and accessibility.

[0074] Furthermore, the use of micro-machining techniques such as micro-saws or wire cutting to form the recess 120 in related technologies results in inconsistent or difficult-to-adjust stiffness among the segments 100 of the existing hypoecho tube. When the proximal end B has sufficient stiffness to push the coil, the stiffness of the distal end A near the coil is too large, resulting in an excessively large minimum bending radius, making it difficult to pass through lumens with smaller bending radii. The hypoecho tube in this embodiment can use laser cutting technology to form the recess 120 on the body 110, making the shape or pattern of the recess 120 more diverse and the cutting parameters controllable. This is beneficial for forming a hypoecho tube that simultaneously possesses good stiffness and flexibility, and can achieve a smaller bending radius while balancing the complex bending stiffness, tensile strength, and torsional strength requirements of the human vascular system and changing the shape of the guidewire as needed.

[0075] The extension direction perpendicular to the recess 120 can also be the normal direction of the recess 120.

[0076] It should be noted that a threaded segment refers to multiple parts divided by the recess 120 along its extension direction. Furthermore, a single threaded segment can only wrap around the body 110 once at most; that is, on a plane perpendicular to the extension direction of the body 110, the orthographic projections of a single threaded segment have no overlapping areas. (The extension direction of the coastal waveguide is shown in the image.) Figure 5 (From left to right) The body portion 110 between adjacent threaded segments can refer to the body portion 110 between adjacent threaded segments of the same recess 120, or the body portion 110 between adjacent threaded segments of adjacent recesses 120.

[0077] It should be noted that, Figures 1-4 The three-dot ellipsis in the text refers to at least one omitted pipe segment. Due to space limitations, it is difficult to draw all of them. Those skilled in the art will understand that the number of pipe segments can be determined according to the actual situation.

[0078] It is understood that the body portion 110 has a tubular structure, and the recess 120 is formed on the circumferential surface of the body portion 110. The recess 120 can be a through groove that extends from the outer circumferential surface of the body portion 110 to the inner circumferential surface, or it can be a groove that does not extend to the inner circumferential surface. The recess 120 is spirally distributed along the circumferential surface of the body portion 110, and the recess 120 can be a continuous structure that extends between multiple tube segments 100.

[0079] It is understandable that the cutting parameters can refer to the parameters of the pattern of the hysteresis tube, such as the pitch X of the ring 111, the length Y of the beam 112, the width D of the recess 120, and the combined length of any recess 120 and an adjacent beam 112.

[0080] In some possible embodiments, the number of recesses 120 is one, spirally wrapped around at least two pipe segments 100.

[0081] In this embodiment, a recess 120 extends in a spiral shape over at least two segments 100 of the sodium hypochlorite tube.

[0082] In some possible embodiments, reference Figure 2 In at least one pipe section 100, at least two recesses 120 extend at intervals on the circumferential surface of the body portion 110 to form a spiral distribution.

[0083] Along the extending direction of the recess 120, the body portion between adjacent recesses 120 forms a beam portion 112.

[0084] Between different pipe sections 100, at least one of the length Y of the beam portion 112 and the combined length of the adjacent recess 120 and the beam portion 112 is different; the length Y of the beam portion 112 is the dimension of the beam portion 112 along the extension direction of the adjacent recess 120, and the length of the recess 120 is the dimension of the recess 120 along the extension direction of the recess 120.

[0085] In this embodiment, there can be multiple recesses 120, which extend at intervals on the circumferential surface of the body portion 110, and the multiple recesses 120 are distributed in a spiral shape. The embodiment of this application uses laser cutting technology to realize the pattern of the recesses 120, which enables the sodium hypochlorite tube to have a balance of curvature, stiffness or flexibility that is currently impossible to achieve using other micro-machining technologies.

[0086] Unlike the previous embodiment, this application also provides an embodiment in which, instead of considering the case of a single recess, the number of recesses 120 is multiple. (See reference) Figure 2 In at least one pipe segment 100, at least two recesses 120 extend at intervals on the circumferential surface of the body portion 110 in a spiral arrangement. Along the extension direction of the recesses 120, a beam portion 112 is formed between adjacent recesses 120 in the body portion. Between different pipe segments 100, at least one of the following is different: the pitch X of the ring portion 111, the length Y of the beam portion 112, the width D of the recesses 120, and the combined length of adjacent recesses 120 and beam portions 112; the length Y of the beam portion 112 is the dimension of the beam portion 112 along the extension direction of adjacent recesses 120, the length of the recess 120 is the dimension of the recess 120 along its extension direction, and the width D of the recess 120 is the distance between the two opposite sides of the recess 120 in the normal direction.

[0087] For reference Figures 5-7 , Figures 5-7Three different pipe segments 100 are shown (namely, the first pipe segment 101, the second pipe segment 102, and the third pipe segment 103, as described below). At least two pipe segments 100 have at least one different parameter, namely, the pitch X of the ring portion 111, the length Y of the beam portion 112, the width D of the recess 120, and the combined length of adjacent recesses 120 and beam portions 112. This results in each pipe segment 100 having different stiffness, thereby giving each pipe segment 100 the required stiffness and flexibility, and providing good traceability and accessibility.

[0088] It should be noted that the threaded recesses 120 are in Figures 5-7 The middle part should be spirally distributed around the body part 110, however, Figures 5-7 These are all schematic diagrams of the submersible tube from a frontal viewing angle. When the inclination angle of the spiral recess 120 is small, they all appear to be arranged approximately parallel to the vertical direction, as will be understood by those skilled in the art. Figures 5-7 The recesses 120 in the middle are actually spirally distributed.

[0089] In related technologies, the stiffness of two adjacent tube segments 100 in a hypochlorous acid (HLA) tube may change abruptly. This can easily cause the lumen at the connection point of the two adjacent tube segments 100 to need to adapt to two bending radii, potentially leading to the connection point getting stuck in the lumen and causing damage or even rupture. Therefore, in some possible embodiments, the stiffness of the multiple tube segments 100 of the HLA tube gradually increases from the distal end A to the proximal end B of the HLA tube.

[0090] In this embodiment, the proximal end B is the end closer to the operator, and the distal end A is the end that extends into the vascular system. The stiffness of the multiple segments 100 of the hypochlorous acid tube gradually increases from the distal end A to the proximal end B. Furthermore, the stiffness of each segment 100 at different locations can also vary sequentially along the direction from the proximal end B to the distal end A, making the stiffness of the hypochlorous acid tube gradually change. This allows for smoother pushing and rotating of the hypochlorous acid tube within the body, helping the catheter provide necessary support in specific locations while maintaining sufficient flexibility in other areas to adapt to the curves within the body.

[0091] In some possible embodiments, in at least one pipe segment 100, at least one recess 120 extends circumferentially along the body portion 110 to form an annular distribution, the annular recess 120 being closer to the proximal end B than the spiral recess 120.

[0092] In this embodiment, the recesses 120 extend circumferentially along the body portion 110 in one or more tube segments 100, forming a ring-shaped distribution. The thiopanthus tube in this embodiment uses a combination of ring-shaped and spiral-shaped recesses 120, which can improve the adaptability of the catheter and make it suitable for complex lesion sites.

[0093] This application also provides specific pattern parameters for some hysteresis tubes. In some possible embodiments, the central angle corresponding to the combined structure of adjacent recesses 120 and beams 112 is not less than 90 degrees and not greater than 115 degrees.

[0094] The pitch X of the ring 111 is not less than 0.02 mm and not more than 0.25 mm.

[0095] The width D of the recess 120 is not less than 0.011 mm and not more than 0.018 mm.

[0096] The central angle corresponding to beam 112 is not less than 8 degrees and not more than 16 degrees.

[0097] In this embodiment, the combined structure of the recess 120 and an adjacent beam 112 can be abstracted as an arc length, the central angle of which is not less than 90 degrees and not more than 115 degrees. The subwoofer provided in this embodiment focuses on the property of stiffness. The central angle corresponding to the combined structure of the recess 120 and an adjacent beam 112 is not less than 90 degrees and not more than 115 degrees, the pitch X of the ring 111 is not less than 0.02 mm and not more than 0.25 mm, the width D of the recess 120 is not less than 0.011 mm and not more than 0.018 mm, and the central angle corresponding to the beam 112 is not less than 8 degrees and not more than 16 degrees. This makes the stiffness distribution of the subwoofer more uniform, optimizes torque transmission, and reduces axial adverse effects.

[0098] In some possible embodiments, the outer diameter of the body portion 110 is no greater than 0.125 mm.

[0099] The central angle corresponding to the combined structure of adjacent recesses 120 and beams 112 is not less than 70 degrees and not greater than 110 degrees.

[0100] The pitch X of the ring 111 is not less than 0.05 mm and not more than 1 mm.

[0101] The width D of the recess 120 is not less than 0.001 mm and not more than 0.006 mm.

[0102] The central angle corresponding to beam 112 is not less than 3 degrees and not more than 50 degrees.

[0103] The sodium hypochlorite tube provided in this embodiment is more suitable for cases where the outer diameter of the body portion 110 is no greater than 0.125 mm. The central angle corresponding to the combined structure of the recess 120 and an adjacent beam portion 112 is no less than 70 degrees and no greater than 110 degrees. The pitch X of the ring portion 111 is no less than 0.05 mm and no greater than 1 mm. The width D of the recess 120 is no less than 0.001 mm and no greater than 0.006 mm. The central angle corresponding to the beam portion 112 is no less than 3 degrees and no greater than 50 degrees. This makes the sodium hypochlorite tube have a more uniform stiffness distribution on the basis that the outer diameter of the body portion 110 is no greater than 0.125 mm, which can optimize the transmission of torque and reduce axial adverse effects.

[0104] Optionally, among multiple tube segments 100, parameters of the submersible tube, such as the pitch X of the annular portion 111, the length Y of the beam portion 112, the width D of the recess 120, and the combined length of any recess 120 and an adjacent beam portion 112, can be varied in a certain way. For example, along the direction from the distal end A to the proximal end B, the pitch X of the annular portion 111 can be gradually varied in a certain way, or the length Y of the beam portion 112 can be gradually varied in a certain way, or the width D of the recess 120 can be gradually varied in a certain way, or the combined length of any recess 120 and an adjacent beam portion 112 can also be gradually varied in a certain way. The stiffness of the submersible tube is also gradually varied, making the push and rotation of the catheter in the body smoother.

[0105] In some possible embodiments, such as Figure 4 As shown, the width D of the recess 120 of the tube segment 100 near the distal end A of the submersible tube (the D of the recess in the tube segment 100 near the distal end A is equal to D+δD) is greater than the width D of the recess 120 of the tube segment 100 near the proximal end B of the submersible tube.

[0106] In this embodiment, without considering other parameters, or in other words, with other parameters fixed, the recess 120 near the distal end A is wider and the recess 120 near the proximal end B is narrower, making the pipe segment 100 near the distal end A softer and more flexible, and the pipe segment 100 near the proximal end B harder and easier to control.

[0107] In some possible embodiments, the length of the recess 120 of the tube segment 100 near the distal end A of the submersible tube is greater than the length of the recess of the tube segment 100 near the proximal end B of the submersible tube.

[0108] In this embodiment, without considering other parameters, or in other words, with other parameters fixed, the recess 120 near the distal end A is longer and the recess 120 near the proximal end B is shorter, making the pipe segment 100 near the distal end A softer and more flexible, and the pipe segment 100 near the proximal end B harder and easier to control.

[0109] In some possible embodiments, such as Figure 2 As shown, the pitch X of the ring portion 111 of the tube segment 100 near the distal end A of the tube is smaller than the pitch X of the ring portion 111 of the tube segment 100 near the proximal end B of the tube (the pitch X of the ring portion 111 in the tube segment 100 near the proximal end B is equal to X + δX).

[0110] In this embodiment, without considering other parameters, or in other words, with other parameters fixed, the pitch X of the ring portion 111 in the tube segment 100 near the distal end A is smaller than the pitch X of the ring portion 111 in the tube segment 100 near the proximal end B, making the tube segment 100 near the distal end A more flexible and adaptable, while the tube segment 100 near the proximal end B is more rigid and easier to control.

[0111] In some possible embodiments, such as Figure 3 As shown, the length Y of the beam portion 112 of the pipe segment 100 near the distal end A of the submersible tube is less than the length Y of the beam portion 112 of the pipe segment 100 near the proximal end B of the submersible tube (the length Y of the beam portion 112 in the pipe segment 100 near the proximal end B is equal to Y+δY).

[0112] In this embodiment, without considering other parameters, or rather, with other parameters constant, the length Y of the beam portion 112 of the tube segment 100 near the distal end A in the sodium hypochlorite tube is less than the length Y of the beam portion 112 of the tube segment 100 near the proximal end B in the sodium hypochlorite tube. This makes the beam portion 112 of the tube segment 100 near the distal end A shorter and more flexible. The tube segment 100 near the proximal end B is more rigid, which enhances torque response.

[0113] Next, this application embodiment will divide the pipe segment 100 into specific first pipe segment 101, second pipe segment 102 and third pipe segment 103 to illustrate how the parameters in each pipe segment 100 change.

[0114] In some possible embodiments, such as Figure 5 As shown, the submersible tube includes a first tube segment 101 near the distal end A.

[0115] In the first pipe section 101, along the extension direction from the distal end A to the proximal end B, the pitch X of the ring portion 111 increases sequentially in the first design manner, while the length Y of the beam portion 112 remains unchanged.

[0116] In this embodiment, the first tube segment 101 is located near the distal end A and is delivered within the vascular system. In the first tube segment 101, along the direction from the distal end A to the proximal end B, the pitch X of the ring portion 111 is increased sequentially according to the first design method, while the length Y of the beam portion 112 remains unchanged, so that the first tube segment 101 gradually hardens in the direction from the distal end A to the proximal end B.

[0117] like Figure 5 As shown, Figure 5 In the middle X, the pitch X of a ring 111 is given. X+δX refers to the pitch X of an adjacent ring 111. The length of the ring 111 increases by δX sequentially from left to right, that is, the ring 111 increases linearly. Figure 5 In the middle Y, it refers to the length Y of a beam 112. The length Y of the beam 112 in the entire first pipe section 101 remains unchanged.

[0118] In some possible embodiments, such as Figure 6 As shown, the submersible tube includes a second tube segment 102 that is farther from the distal end A than the first tube segment 101.

[0119] In the second pipe section 102, along the extension direction from the distal end A to the proximal end B, the pitch X of the ring portion 111 is increased in a second design manner, and the length Y of the beam portion 112 is increased in a third design manner.

[0120] In this embodiment, the second pipe segment 102 is farther from the distal end A than the first pipe segment 101. In the direction from the distal end A to the proximal end B, the pitch X of the ring portion 111 is increased in a second design manner, and the length Y of the beam portion 112 is increased in a third design manner, that is, the length Y of both the ring portion 111 and the beam portion 112 is increased, so that the second pipe segment 102 gradually hardens in the direction from the distal end A to the proximal end B.

[0121] like Figure 6 As shown, Figure 6 In the middle X, the pitch X of a ring 111 is given. X+δX refers to the pitch X of an adjacent ring 111. The length of the ring 111 increases by δX sequentially from left to right, that is, the ring 111 increases linearly. Figure 6 In the middle Y, Y refers to the length Y of a beam section 112, and Y+δY refers to the length Y of an adjacent beam section 112. Along the direction from left to right, the length of beam section 112 increases by δY sequentially, that is, beam section 112 increases linearly.

[0122] It is understandable that the extension direction of the coastal waveguide (i.e. Figure 6 (From left to right) There may be a whole recess 120 between two adjacent beams 112.

[0123] In some possible embodiments, the submersible tube includes a third segment 103 that is closer to the proximal end B than the second segment 102.

[0124] In the third pipe section 103, along the direction from the distal end A to the proximal end B, the pitch X of the ring portion 111 and the length Y of the beam portion 112 remain unchanged.

[0125] In this embodiment, the third tube segment 103 is further away from the distal end A than the second tube segment 102, and the length Y of the ring portion 111 and the beam portion 112 remains unchanged along the direction from the distal end A to the proximal end B. This makes the third tube segment 103 have sufficient rigidity, which helps to improve the transmission of torque and allows the operator to control the direction and position of the hypotube more precisely, especially in surgery that requires delicate operation.

[0126] like Figure 5 As shown, Figure 7 In the middle, X refers to the pitch X of a ring section 111, and Y refers to the length Y of a beam section 112. The length Y of the ring section 111 and the beam section 112 remains unchanged throughout the entire third pipe section 103.

[0127] In some possible embodiments, the first design, the second design, and the third design each include at least one of linear, exponential, or logarithmic methods.

[0128] In this embodiment, the first, second, and third design methods can be the same or different, depending on the specific circumstances. Each design method can be a linear, exponential, or logarithmic change in a mathematical sense, or other undescribed changes due to space limitations. The design methods provided in this embodiment are all easily implemented using laser cutting technology, which is beneficial for forming a subliminal tube with gradually changing stiffness.

[0129] In some possible embodiments, the body portion 110 includes a plurality of sub-portions divided circumferentially.

[0130] Between at least two sub-parts, at least one of the following is different: the pitch X of the ring 111, the length Y of the beam 112, the width D of the recess 120, and the combined length of the adjacent recess 120 and the beam 112.

[0131] In this embodiment, the body portion 110 can be divided into multiple parallel sub-portions along its circumference. Between regions containing at least two sub-portions, at least one of the following parameters is different: the pitch X of the ring portion 111, the length Y of the beam portion 112, the width D of the recess 120, and the combined length of any recess 120 and an adjacent beam portion 112. For example, in a cross-section perpendicular to the axial direction of the body portion 110, the pattern of the hypochlorous acid tube is not symmetrical about the axial direction of the body portion 110, but the patterns in different sub-portions have certain differences, making some sub-portions easier to bend. This results in a preferred bending direction at a specific location of the hypochlorous acid tube, making it easier for the hypochlorous acid tube to bend in a predetermined direction and extend into the vascular system, thus simplifying the directional control of the hypochlorous acid tube.

[0132] It is understood that the axial direction of the body portion 110 is the same as the extension direction of the body portion 110 and passes through the center of the body portion 110.

[0133] Please refer to Figures 8-9 In some possible embodiments,

[0134] Along the radial direction of the coastal wave tube toward the center, the width of the recess 120 gradually decreases.

[0135] In this embodiment, more material is removed from the outer side 114 of the body portion 110, while less material is removed from the inner side 113. This allows the formed recess 120 to provide additional space for adjacent ring portions to approach each other, further preventing adjacent ring portions 111 from abutting against each other. Consequently, compared to a vertically recessed recess 120, a smaller bending radius is achieved. This prevents or avoids collisions between rings when the guidewire passes through tortuous vessels in the distal intracranial region, thus preventing the guidewire from having an excessively large bending radius and failing to reach the intended lesion location. Therefore, flexibility is further improved, and the guidewire is more compliant with the tortuous anatomy of the blood vessels, thereby further reducing friction, traction, and nerve damage to the blood vessels.

[0136] Please refer to Figures 8-9 In some possible embodiments, an angle is formed between the two opposite sides of the recess 120 in the extending direction of the hysteresis tube.

[0137] In this embodiment, an angle is formed between the two opposing sides of the recess 120, such that at least one of the opposing sides of the recess 120 has an angle with the inner or outer surface of the adjacent ring 111. This ensures a balance in the flexibility, tensile strength, and torque transmission properties of the guidewire, reducing the phenomenon of the guidewire being close to the blood vessel wall and lowering the friction during delivery. At the same time, it ensures that the pushing force and torque control force are smoothly transmitted from the proximal end of the guidewire to the distal end of the guidewire.

[0138] Based on the same inventive concept, this application also provides a guide wire, including: a core wire, a coil, and any of the hysteresis tubes provided in the above embodiments.

[0139] The coil is wrapped around the outer periphery of the distal end of the core wire.

[0140] The sodium thiosulfate tube is tubular and is fitted around a portion of the coil and a portion of the core wire.

[0141] The guidewire provided in this embodiment includes any of the sodium hypochlorite tubes provided in the above embodiments, and their implementation principles are similar, so they will not be repeated here. The sodium hypochlorite tube may only cover the core wire and coil, with portions of both the core wire and coil protruding from the sodium hypochlorite tube; the specific arrangement depends on the actual situation.

[0142] By applying the embodiments of this application, at least the following beneficial effects can be achieved:

[0143] 1. The subwoofer tube in this embodiment includes at least two tube segments 100. The stiffness of the tube segment 100 near the proximal end B of the subwoofer tube is greater than that of the tube segment 100 near the distal end A of the subwoofer tube, so that different tube segments 100 have their own required stiffness and flexibility, and have good trackability and accessibility. Moreover, in related technologies, micro-machining techniques such as micro-saws or wire cutting are used to form the recess 120, which results in the existing subwoofer tubes having uniform stiffness of each tube segment 100 or being difficult to adjust. When the proximal end B has sufficient stiffness to push the coil, the stiffness of the distal end A near the coil is too large, and the minimum bending radius is too large, making it difficult to pass through the cavity with a small bending radius. The sodium hypochlorite tube in this embodiment can form a recess 120 on the body 110 using laser cutting technology, which makes the shape or pattern of the recess 120 more varied and the cutting parameters controllable. This is beneficial for forming a sodium hypochlorite tube that has both good rigidity and flexibility. It can achieve a smaller bending radius when changing the shape of the guidewire as needed, while balancing the complex bending rigidity, tensile strength and torsional strength requirements of the human vascular system.

[0144] 2. There can be multiple recesses 120, which extend at intervals on the circumferential surface of the main body 110, and the overall distribution of the multiple recesses 120 is spiral. The embodiments of this application use laser cutting technology to realize the pattern of the recesses 120, which enables the hysteresis tube to have a balance of curvature, stiffness or flexibility that is currently impossible to achieve using other micro-machining technologies.

[0145] 3. The recesses 120 extend circumferentially along the body portion 110 in one or more tube segments 100, forming a ring-shaped distribution. In this embodiment, the thiopanthus tube uses a combination of ring-shaped and spiral-shaped recesses 120, which can improve the adaptability of the catheter and is suitable for complex lesion sites.

[0146] 4. Among multiple tube segments 100, parameters of the submersible tube, such as the pitch X of the annular portion 111, the length Y of the beam portion 112, the width D of the recess 120, and the combined length of any recess 120 with an adjacent beam portion 112, can be varied in a certain way. For example, along the direction from the distal end A to the proximal end B, the pitch X of the annular portion 111 can be gradually varied in a certain way, or the length Y of the beam portion 112 can be gradually varied in a certain way, or the width D of the recess 120 can be gradually varied in a certain way, or the combined length of any recess 120 with an adjacent beam portion 112 can also be gradually varied in a certain way. The stiffness of the submersible tube is also gradually varied, making the push and rotation of the catheter in the body smoother.

[0147] In the description of this application, the terms "center," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," and "outer," etc., indicate directions or positional relationships based on the exemplary directions or positional relationships shown in the accompanying drawings. They are used to facilitate the description or simplification of the embodiments of this application and are not intended to indicate or imply that the device or component referred to must have a specific orientation or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application.

[0148] The terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this application, unless otherwise stated, "a plurality of" means two or more.

[0149] In the description of this application, it should be noted that, unless otherwise expressly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal communication between two components. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0150] In the description of this specification, specific features, structures, materials, or characteristics may be combined in any suitable manner in one or more embodiments or examples.

[0151] The above description is only a partial implementation of this application. It should be noted that for those skilled in the art, other similar implementation methods based on the technical concept of this application, without departing from the technical concept of this application, also fall within the protection scope of the embodiments of this application.

Claims

1. A sodium hypochlorite tube, used in guidewires, characterized in that, It includes at least two pipe segments sequentially distributed along the extension direction of the hysteresis tube; the hysteresis tube includes: a body portion and a recess formed in the body portion; In at least one of the pipe sections, at least one of the recesses extends on the circumferential surface of the body portion in a spiral distribution, including a plurality of threaded segments arranged along the extension direction of the recess; Along the extension direction of the hyaluronic acid tube, a ring is formed in the body portion between adjacent threaded segments; The stiffness of the pipe section near the proximal end of the thiourea tube is greater than the stiffness of the pipe section near the distal end of the thiourea tube. Between different pipe segments, at least one of the pitch of the annulus and the width of the recess is different; the width of the recess is the distance between two opposite sides of the recess in the direction perpendicular to the extension of the recess; the pitch of the annulus is the width of the body portion between the threaded segments of adjacent recesses; along the extension direction of the recess, the body portion between adjacent recesses forms a beam portion; The hysteresis tube includes a first tube segment near the distal end and a second tube segment farther away from the distal end compared to the first tube segment; In the second pipe section, along the extension direction from the distal end to the proximal end, the pitch of the ring portion is increased in a second design manner, and the length of the beam portion is increased in a third design manner.

2. The sodium hypochlorite tube according to claim 1, characterized in that, The number of recesses is one, which spirals around at least two of the pipe sections.

3. The sodium hypochlorite tube according to claim 1, characterized in that, The number of the recesses is multiple; In at least one of the pipe sections, at least two of the recesses extend at intervals on the circumferential surface of the body portion to form a spiral distribution; Between different pipe segments, at least one of the length of the beam portion and the combined length of the adjacent recess and the beam portion is different; the length of the beam portion is the dimension of the beam portion along the extension direction of the adjacent recess, and the length of the recess is the dimension of the recess along the extension direction of the recess.

4. The sodium hypochlorite tube according to claim 1, characterized in that, The stiffness of the plurality of segments of the hysteresis tube gradually increases from the distal end of the hysteresis tube to the proximal end of the hysteresis tube.

5. The sodium hypochlorite tube according to claim 1, characterized in that, In at least one of the pipe segments, at least one of the recesses extends circumferentially along the body portion to form a ring-shaped distribution, and the ring-shaped recesses are closer to the proximal end than the spirally distributed recesses.

6. The sodium hypochlorite tube according to claim 3, characterized in that, The central angle corresponding to the combined structure of adjacent recesses and beams is not less than 90 degrees and not greater than 115 degrees; The pitch of the ring is not less than 0.02 mm and not more than 0.25 mm; The width of the recess is not less than 0.011 mm and not more than 0.018 mm; The central angle corresponding to the beam is not less than 8 degrees and not more than 16 degrees.

7. The sodium hypochlorite tube according to claim 3, characterized in that, The outer diameter of the main body is no greater than 0.125 mm; The central angle corresponding to the combined structure of adjacent recesses and beams is not less than 70 degrees and not greater than 110 degrees; The pitch of the ring is not less than 0.05 mm and not more than 1 mm; The width of the recess is not less than 0.001 mm and not more than 0.006 mm; The central angle corresponding to the beam is not less than 3 degrees and not more than 50 degrees.

8. The sodium hypochlorite tube according to claim 3, characterized in that, The width of the recess in the pipe section near the distal end of the thiocyanate tube is greater than the width of the recess in the pipe section near the proximal end of the thiocyanate tube.

9. The sodium hypochlorite tube according to claim 3, characterized in that, The length of the recess in the pipe segment near the distal end of the thiourea tube is greater than the length of the recess in the pipe segment near the proximal end of the thiourea tube.

10. The sodium hypochlorite tube according to claim 3, characterized in that, The pitch of the annulus portion of the tube segment near the distal end of the thiopancreatic tube is smaller than the pitch of the annulus portion of the tube segment near the proximal end of the thiopancreatic tube.

11. The sodium hypochlorite tube according to claim 3, characterized in that, The length of the beam portion of the pipe segment near the distal end of the hyaluronic acid tube is less than the length of the beam portion of the pipe segment near the proximal end of the hyaluronic acid tube.

12. The sodium hypochlorite tube according to claim 3, characterized in that, In the first pipe section, along the extension direction from the distal end to the proximal end, the pitch of the ring portion increases sequentially according to a first design method, while the length of the beam portion remains unchanged.

13. The sodium hypochlorite tube according to claim 12, characterized in that, The hysteresis tube also includes a third tube segment that is closer to the proximal end than the second tube segment; In the third pipe section, the pitch of the ring and the length of the beam remain unchanged in the direction from the distal end to the proximal end.

14. The sodium hypochlorite tube according to claim 13, characterized in that, The first design method, the second design method, and the third design method each include at least one of linear, exponential, or logarithmic methods.

15. The sodium hypochlorite tube according to claim 1, characterized in that, The main body includes multiple sub-parts divided along the circumferential direction; Between at least two of the sub-parts, at least one of the following is different: the pitch of the ring portion, the length of the beam portion, the width of the recess portion, and the combined length of adjacent recess portions and beam portions.

16. The sodium hypochlorite tube according to claim 1, characterized in that, Along the radial direction of the hyaluronic acid tube toward the center, the width of the recess gradually decreases.

17. The sodium hypochlorite tube according to claim 16, characterized in that, In the extending direction of the hyaluronic acid tube, an angle is formed between the two opposite sides of the recess.

18. A guidewire, characterized in that, include: Core wire, coil, and hyaluronic acid tube as described in any one of claims 1-17 above; The coil is wrapped around the outer periphery of the distal end of the core wire; The sodium thiosulfate tube is tubular and is fitted around a portion of the coil and a portion of the core wire.

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