Rs17771861 and application thereof in preparation of reagent for nasopharyngeal carcinoma prognosis prediction

By detecting the SNP site rs17771861 in the peripheral blood of patients with nasopharyngeal carcinoma, it provides the prognosis prediction of nasopharyngeal carcinoma, solves the problem of lack of prognostic markers in the prior art, and achieves the accuracy of individualized treatment and improves survival.

CN120485373APending Publication Date: 2025-08-15THE THIRD XIANGYA HOSPITAL OF CENT SOUTH UNIV
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Patent Information

Application Number
CN202510794405.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-06-13
Publication Date
2025-08-15

AI Technical Summary

Technical Problem

The lack of effective prognostic markers for nasopharyngeal carcinoma in the prior art leads to significant differences in prognostic outcomes after treatment and the inability to achieve precise treatment.

Method used

Using SNP site rs17771861 and its related kits, we provide prognosis prediction of nasopharyngeal carcinoma by detecting the SNP site genotype in peripheral blood, and formulate individualized treatment plans.

Benefits of technology

It improves the accuracy and survival rate of prognostic evaluation in patients with nasopharyngeal carcinoma, provides guidance for individualized treatment, is convenient for detection and simple for operation.

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Abstract

The invention belongs to the field of tumor medicine and the technical field of molecular biology and gene detection, and relates to application of rs17771861 in preparation of a nasopharyngeal carcinoma prognosis prediction marker, and the sequence of the SNP site rs17771861 is as shown in SEQ ID NO.1. The invention also relates to application of the SNP site rs17771861 in preparation of a nasopharyngeal carcinoma prognosis prediction marker. The invention provides an SNP (Single Nucleotide Polymorphism) marker rs17771861 related to nasopharyngeal carcinoma prognosis, application of the SNP marker rs17771861 and a detection kit capable of being used for nasopharyngeal carcinoma prognosis prediction, and the SNP marker rs17771861 is used for assisting in guiding individualized treatment and improving prognosis of tumor patients. After the kit disclosed by the invention is applied to clinical detection, prognosis of a patient can be evaluated before treatment, and a more positive and effective treatment scheme is formulated for the patient with poor prognosis, so that individualized treatment of the patient is realized, and the survival rate is increased. In addition, the kit only needs to detect peripheral blood, and has the characteristics of convenience in sampling, simplicity in operation, high timeliness and the like.
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