A wound antiseptic gel and method of preparation thereof

By preparing PCA-HBPG cross-linked modified chitosan, and combining it with iodine and curcumin to form a Schiff base bond cross-linked gel, the problems of easy drying and short-lived antibacterial effect of existing wound repair products are solved, achieving a long-lasting effect of rapid sterilization and promoting wound healing.

CN120678721BActive Publication Date: 2025-10-21PINGYANG COUNTY PEOPLES HOSPITAL
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Patent Information

Application Number
CN202511194906.6
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-08-26
Publication Date
2025-10-21
Estimated Expiration
2045-08-26

AI Technical Summary

Technical Problem

Existing wound repair products tend to cause wounds to dry out, damage healthy growth factors, and have a long healing time. Furthermore, existing silver ion disinfectant gels require high concentrations and have short-lived antibacterial effects.

Method used

By preparing PCA-HBPG cross-linked modified chitosan and combining it with components such as iodine and curcumin, a Schiff base cross-linked gel is formed, which is loaded with iodine and curcumin to achieve long-lasting antibacterial effect and promote healing.

Benefits of technology

It achieves rapid killing of bacteria and fungi on wounds, promotes wound healing, improves antibacterial long-term efficacy and healing effect, and enhances the sustained release and stability of active ingredients.

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Abstract

The present application relates to the technical field of wound gel, in particular to a kind of wound antibacterial disinfectant gel and preparation method thereof.Preparation raw materials of the wound antibacterial disinfectant gel include the following components by weight: PCA-HBPG 4-6 parts, modified chitosan 6-9 parts, 3-amino phenylboric acid 1.5-2 parts, iodine 0.6-0.9 parts, potassium iodide 1.2-1.8 parts, curcumin 0.8-1 part, and the prepared antibacterial disinfectant gel has good bacteriostatic effect, and can promote wound healing.
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