Medicine for improving oral micro-ecology based on perilla leaves and application thereof
The medicine prepared from perilla leaf extract solves the problem of harmful oral bacteria causing systemic diseases. By increasing the secretion of mucosal immunoglobulins and regulating the oral microecology, it inhibits harmful bacteria and promotes beneficial bacteria, thereby improving oral health.
CN120678827APending Publication Date: 2025-09-23HEILONGJIANG ACAD OF TCM
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Patent Information
- Application Number
- CN202510915270.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Priority Date
- 2024-12-19
- Filing Date
- 2025-07-03
- Publication Date
- 2025-09-23
AI Technical Summary
Technical Problem
Harmful oral bacteria cause systemic diseases in humans, and existing technologies are difficult to effectively improve the oral microecology.
Method used
The medicine is prepared from perilla leaf extract, which is extracted with water or ethanol to increase the secretion of immunoglobulin in the oral mucosa, inhibit the growth of harmful bacteria, and promote the growth of beneficial bacteria. The medicine can be made into sprays, liquids, lozenges, or mixed into oral products for use.
Benefits of technology
Increase the secretion of immunoglobulin in the oral mucosa, inhibit harmful bacteria, promote the growth of beneficial bacteria, improve the oral microenvironment, and reduce bad breath.
✦ Generated by Eureka AI based on patent content.
Abstract
The invention relates to a medicine for improving oral micro-ecology based on perilla leaves and application thereof, in particular to a medicine for improving oral micro-ecology based on perilla leaves and application thereof. The invention aims to solve the problem of human systemic diseases caused by oral harmful bacteria. The method comprises the following steps: crushing the perilla leaves, adding distilled water or ethanol with a volume concentration of 50% according to a mass ratio of the perilla leaves to the distilled water or ethanol with a volume concentration of 50% of 1: 20, soaking the distilled water in a closed container for 12 h, decocting for 3 h, and taking a filtrate; extracting with ethanol with the volume concentration of 50%, soaking in a closed container for 3 hours, performing ultrasonic extraction for 30 minutes, and taking filtrate; and repeatedly extracting the remaining medicines once, combining filtrates, concentrating the filtrates under reduced pressure, freeze-drying, preparing a solution with the medicine content of 1mg / mL by using distilled water, and sterilizing by using a 0.22 mu m filter membrane, thereby obtaining the traditional Chinese medicine composition. The medicine for improving the oral micro-ecology based on the perilla leaves is used for improving oral mucosa immune globulin. Through the perilla leaf extract, the secretion amount of immune globulin in oral mucosa is increased, and the oral microenvironment is improved.
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