Non-therapeutic-purpose auditory perception training device and method for noninvasive free mouse training stimulation auditory cortex plasticity and application

Through a non-invasive and free mouse auditory perception training device and method, using on-track training and reward-punishment mechanism, the traumatic problem of existing mouse auditory perception training is solved, and the extensive induction of auditory cortex plasticity and improvement of auditory function are achieved.

CN120713073APending Publication Date: 2025-09-30EAST CHINA NORMAL UNIV
1 Cites 1 Cited by

Patent Information

Application Number
CN202510008799.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-03
Publication Date
2025-09-30

AI Technical Summary

Technical Problem

Existing auditory perception training methods for mice are highly traumatic and have fixed training methods. They cannot widely induce auditory cortex plasticity and are difficult to effectively improve auditory cortex function in adult animals.

Method used

A non-invasive, free auditory perception training device and method for mice was designed. The training device body and processing control system were used in a soundproof box. The animals were trained freely in a runway, combined with water administration and air blowing rewards and punishments, to achieve extensive induction of plasticity in the mouse auditory cortex.

Benefits of technology

Non-invasive and painless plasticity training of the auditory cortex of mice was achieved, which improved the frequency selectivity and discrimination ability of auditory cortical neurons in adult animals and is suitable for improving neurological problems such as autism.

✦ Generated by Eureka AI based on patent content.
Patent Text Reader

Abstract

The invention discloses a non-therapeutic-purpose hearing and perception training device for non-invasive free mouse training and auditory cortex plasticity stimulation. The device comprises a soundproof box, a training device body in the soundproof box and a processing control system located outside the soundproof box. The training device main body in the soundproof box comprises a training box body, a water and air supply device, an animal action sensing device, an animal position sensing device, a loudspeaker and an illuminating lamp; the training box body comprises an open box and a dark box, and the animal position sensing device is arranged at the relative position of the junction of the open box and the dark box and the relative position of the side wall of the dark box; the processing control system located outside the soundproof box comprises a water and gas control device, a power amplifier and a control computer. The invention further discloses a method and application of the training device in auditory cortex plasticity induction and auditory perception training, and the training device has wide application prospects.
Need to check novelty before this filing date? Find Prior Art