Reagent mixing processor for medical immunological examination
By designing a reagent mixing processor for medical immunoassay that drives the carrier shell to swing in a circular motion using a drive unit, the problem of bubble generation and active substance inactivation caused by vigorous mixing in existing devices has been solved. This achieves a highly efficient and gentle mixing effect, making it suitable for immunoassay experiments.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- HEILONGJIANG UNIV OF CHINESE MEDICINE
- Filing Date
- 2025-07-11
- Publication Date
- 2026-04-28
AI Technical Summary
Existing mixing devices use violent and uncontrollable mixing methods, which can easily lead to bubble formation and inactivation of active substances, making it difficult to meet the needs of immunoassay experiments that require gentle mixing.
A reagent mixing processor for medical immunological testing was designed. The driving unit drives the carrier shell to make a circular swing in the horizontal direction, and the fixed component swings synchronously, simulating a gentle artificial swinging motion to achieve circumferential shaking at the bottom of the container, avoiding violent stirring and vibration.
It achieves efficient and gentle mixing, avoids bubble formation and loss of active substances, improves the consistency of the reaction system and the stability of the detection results, and is suitable for sensitive reagent systems such as antibodies, antigens, and colloidal gold.
Smart Images

Figure CN120754743B_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of immunoassay, specifically to a reagent mixing processor for medical immunoassay. Background Technology
[0002] In many fields such as medical experiments, immunoassay, and molecular biology detection, thorough mixing of reagents and samples is a crucial step in ensuring the accuracy and stability of the reaction system. Existing mixing devices mainly include two types of structures: vortex mixers and up-and-down oscillators.
[0003] Vortex mixers achieve rapid mixing by inducing violent agitation of the liquid through high-frequency, high-speed rotating vibrators contacting the bottom of the container. Up-and-down oscillating mixers, on the other hand, agitate the liquid through the linear reciprocating motion of the container. While these structures can achieve a certain degree of mixing in a short time, they also have the following significant drawbacks:
[0004] The mixing process is violent and uncontrollable, and it is easy to introduce a large number of air bubbles, especially when processing high-protein, high-sensitivity enzymes or colloidal samples, which can easily lead to the inactivation of bioactive substances or reaction errors.
[0005] It is difficult to simulate the standard mixing action of "gentle swaying" in artificial experiments, resulting in poor performance in some reaction systems that require gentle perturbation (such as immune binding).
[0006] Therefore, a reagent mixing processor for medical immunological testing is provided to address the above-mentioned problems. Summary of the Invention
[0007] In order to solve the problems of existing mixing devices, such as violent and uncontrollable mixing methods, difficulty in simulating gentle human swirling motion, easy generation of bubbles and inactivation of active substances, and difficulty in meeting the experimental needs of immunoassay and other tests that require gentle mixing, this invention provides a reagent mixing processor for medical immunoassay.
[0008] The present invention solves the above-mentioned technical problems through the following technical solutions:
[0009] The present invention provides a reagent mixing processor for medical immunological testing, including a worktable, wherein a drive unit is disposed inside the worktable, the drive unit passing through the top side wall of the worktable housing and being biasedly connected to the support shell.
[0010] The drive unit causes the carrier shell to swing in a circular motion in the horizontal direction;
[0011] The support shell is located at the top of the workbench and overlaps with the annular support plate at the top of the workbench shell. The support plate is used to support the support shell, and the drive unit does not bear the support function.
[0012] A fixing component for fixing reagent containers, wherein there are several fixing components and the several fixing components are evenly distributed on the carrier shell;
[0013] The fixing component is clamped in the middle or upper middle part of the container, and as the supporting shell swings, the container swings in a circular motion around the clamping point.
[0014] The workbench is equipped with a control panel, which is used to control the start and speed of the drive motor. The connection method between the control panel and the drive motor, as well as the power supply method of the drive motor, are all existing technologies and will not be described in detail in this technical solution.
[0015] Furthermore, for the drive motor and control panel, you can choose the models commonly used in mixing equipment.
[0016] In this technical solution, the driving unit includes a driving motor, the output end of the driving motor is arranged facing upward, and a driving shaft in the shape of a "Z" is fixed on the output end of the driving motor;
[0017] The top of the drive shaft passes sequentially through the through groove at the top of the workbench housing and the inner ring of the bearing ring, and is fixedly connected to the circular connecting block at the bottom of the bearing housing. The connecting block is located in the inner ring cavity of the bearing ring.
[0018] The connecting block is fixed at an off-center position at the bottom of the bearing shell, and the drive motor is fixed to the side wall at the bottom of the inner cavity of the worktable via an "L"-shaped connector.
[0019] The drive motor drives the carrier shell to swing in a circular trajectory via the drive shaft.
[0020] In this technical solution, the fixing component includes a mounting shell, and a clamping part for clamping and fixing the container is provided above the inner cavity of the mounting shell;
[0021] The clamping part includes an outer support unit and an inner clamping unit, wherein the inner clamping unit clamps and fixes the container;
[0022] The inner clamping unit is fitted inside the outer support unit, and the inner clamping unit rotates inside the outer support unit. The outer support unit is fixedly mounted on the shell.
[0023] Specifically, the inner clamping unit holds the container, and the inner clamping unit can rotate inside the outer supporting unit, thus providing a structural basis for the container to swing.
[0024] In this technical solution, the outer surface of the inner clamping unit and the outward extension surface of the outer surface form a complete spherical structure, and the inner cavity surface of the outer support unit and the outward extension surface of the inner cavity surface form a complete spherical structure. That is, the contact surface between the inner clamping unit and the outer support unit is a spherical structure, and a universal rotating connection structure is formed between the inner clamping unit and the outer support unit to facilitate the clamping part to clamp the container and swing in the horizontal direction.
[0025] In this technical solution, the outer support unit includes multiple limiting covers arranged in a ring array. Two adjacent limiting covers are connected to each other by connecting arc rods. At least two limiting covers have support rods fixed on their outer walls, and the support rods are fixed to the inner wall of the mounting shell.
[0026] The inner walls of all the limiting covers together form a spherical structure, and the limiting covers are attached to the outer wall of the inner clamping unit.
[0027] The inner clamping unit rotates within the spherical cavity enclosed by all the limiting outer covers.
[0028] In this technical solution, the inner clamping unit includes a rotating shell with an overall annular structure and a spherical outer wall, and the outer wall of the rotating shell is fitted with the inner wall of the limiting outer cover;
[0029] A clamping element is disposed in the inner cavity of the rotating shell, clamps the surface of the container, and the container passes through the rotating shell.
[0030] The clamping element clamps the container, and the clamping element rotates with the rotating shell inside the spherical cavity enclosed by the limiting outer cover.
[0031] In this technical solution, the clamping member includes two symmetrically arranged clamping arc plates, which are connected to the inner wall of the rotating shell via a first telescopic rod arranged in the horizontal direction;
[0032] A first spring is fitted onto the surface of the first telescopic rod, and the container is held by the elastic force provided by the first spring.
[0033] Specifically, a container containing reagents and samples is inserted between two clamping arc plates. The two clamping arc plates are pushed outward, clamping the container in the middle or upper middle part. At this time, the first spring deforms, and the elastic force generated by the potential energy of the first spring recovering its deformation clamps the container.
[0034] A clamping layer made of soft rubber can be bonded to the clamping arc plate to increase the static friction between the clamping arc plate and the container.
[0035] If necessary, the appropriate stopper can be placed at the entrance of the container during mixing.
[0036] In this technical solution, a counterweight is also included to facilitate the movement of the clamping part. The counterweight includes two symmetrically arranged "L"-shaped synchronous rods. The vertical parts of the two synchronous rods are distributed along both sides of the clamped container and extend to the bottom of the container. The horizontal parts of the two synchronous rods are located at the bottom of the container and are both connected to the top of the counterweight block. The counterweight block is located directly below the two clamping arc plates.
[0037] The top of the synchronizing rod is fixed to the telescopic end of the first telescopic rod;
[0038] Furthermore, the horizontal part of the synchronizing rod is telescopic, meaning that the horizontal part of the synchronizing rod and the first telescopic rod extend and retract synchronously.
[0039] The counterweight can lower the center of gravity of the fixed part and increase the center of gravity of the bottom of the container, so that it can swing better with the support shell and facilitate the clamping part to hold the container in motion.
[0040] It also includes two symmetrically arranged auxiliary fixing units, which are distributed on both sides of the two synchronizing rods;
[0041] The auxiliary fixing unit includes a driving component and an auxiliary component for clamping the container. The driving component is disposed on the retractable area of the vertical portion of the synchronizing rod, and the driving component pushes the auxiliary component to clamp the container surface as the retractable area of the vertical portion of the synchronizing rod extends.
[0042] The telescopic area of the vertical part of the synchronizing rod is a second telescopic rod set vertically, and the second telescopic rod replaces the middle area of the original vertical part of the synchronizing rod.
[0043] The driving component is a self-rotating transmission roller, which is installed at the bottom end of the second telescopic rod. The downward-moving transmission roller is connected to the auxiliary component.
[0044] The auxiliary component includes a transmission block, the top of which is provided with a transmission ramp, the transmission ramp overlapping with a transmission roller, and the transmission block being slidable in the horizontal direction;
[0045] An auxiliary clamping plate for holding the container is fixed on the transmission block, and the auxiliary clamping plate and the transmission inclined surface are located on both sides of the transmission block.
[0046] Both sides of the transmission block are provided with connecting parts. Each connecting part includes a fixed rod with an "L" shape. A slider is fixed to the top of the fixed rod. The slider is slidably connected to a horizontal guide rail arranged in the horizontal direction. The horizontal guide rail is arranged parallel to the first telescopic rod. The top of the horizontal guide rail is connected to the telescopic end of the first telescopic rod through a connecting vertical rod, and the connecting vertical rod is located inside the second telescopic rod.
[0047] A second spring is fitted onto the surface of the second telescopic rod, and the length of the second telescopic rod is maintained by the second spring without providing additional potential energy support.
[0048] One end of the slider is connected to the third spring, and the other end of the third spring is fixed on the guide rail. When the clamping arc plate is clamped on the container surface under normal conditions, the auxiliary clamping plate does not contact the container surface.
[0049] The top and bottom of the second telescopic rod are connected by a "Z"-shaped connecting rod and a synchronizing rod, increasing the distance between the second telescopic rod and the connecting vertical rod to facilitate the installation of the transmission block.
[0050] When the second spring is in its normal state, the third spring does not deform.
[0051] Based on common knowledge in the field, the above-mentioned preferred conditions can be combined arbitrarily to obtain various preferred embodiments of the present invention.
[0052] The positive and progressive effects of this invention are as follows:
[0053] This device, through a drive unit, causes the supporting shell located on it to swing in a horizontal circular trajectory, which in turn drives the fixed components connected to the supporting shell to swing synchronously, thereby achieving circumferential shaking of the bottom of the clamped container (such as a test tube, sample tube, etc.). This circumferential shaking structure simulates the mixing motion of a person holding the middle of a test tube and gently swirling it, enabling efficient and gentle mixing of reagents and samples in the container without relying on high-speed vortex stirring or magnetic stirring.
[0054] Compared to traditional vortex mixers or up-and-down oscillating mixing structures, this device has the following advantages:
[0055] High mixing uniformity avoids insufficient local reaction.
[0056] The circular motion at the bottom of the container creates continuous disturbance and annular flow of reagents and samples throughout the liquid space, effectively breaking the mixing layer difference between the liquid surface and the bottom, and improving the consistency of the reaction system and the stability of the detection results.
[0057] Avoid bubbles and loss of activity caused by vigorous stirring
[0058] The mixing process is free from strong impacts and discontinuous oscillations, effectively avoiding the generation of bubbles and the structural damage of active substances such as proteins and enzymes caused by traditional high-speed vortex mixing. It is particularly suitable for immune reagent systems that are sensitive to mechanical disturbances, such as antibodies, antigens, colloidal gold, and magnetic beads.
[0059] Simulates human operation trajectory and has biomimetic mixing characteristics.
[0060] The circular swing structure simulates the classic experimental action of "holding the middle of the test tube and gently rotating it", giving the device a natural and gentle human-machine process logic, and making it highly adaptable and reliable in scenarios where automation replaces manual operation.
[0061] Simple structure, low power consumption, suitable for integration in multiple scenarios
[0062] It requires no auxiliary devices such as magnetic stir bar or heating platform, has a compact overall structure, is easy to control, and can be integrated as a module into small and medium-sized automated equipment such as immunoassay analyzers, PCR sample loading systems, and rapid detection platforms.
[0063] Reduce human error and improve experimental consistency and efficiency.
[0064] The fixed shaking trajectory and parameter settings standardize the mixing action between different batches and different operators, effectively improving experimental repeatability and data comparability, and are especially suitable for high-throughput or continuous sample processing. Attached Figure Description
[0065] Figure 1 This is a three-dimensional structural diagram of the overall external structure of the present invention;
[0066] Figure 2 For the present invention Figure 1 A top-view structural diagram;
[0067] Figure 3 For the present invention Figure 2 Schematic diagram of the cross-sectional structure at point AA;
[0068] Figure 4 For the present invention Figure 2 Schematic diagram of the cross-sectional structure at BB;
[0069] Figure 5 This is a schematic diagram of the external three-dimensional structure of the fixing component of the present invention;
[0070] Figure 6 For the present invention Figure 5 A top-view structural diagram;
[0071] Figure 7 For the present invention Figure 6 A schematic diagram of the cross-sectional structure at point CC;
[0072] Figure 8 This is a schematic diagram of the connection structure between the clamping part and the container of the present invention;
[0073] Figure 9 For the present invention Figure 8 A top-view structural diagram;
[0074] Figure 10 For the present invention Figure 9Schematic diagram of the cross-sectional structure at DD;
[0075] Figure 11 This is a schematic diagram of the clamping part of the present invention;
[0076] Figure 12 This is a schematic diagram of the vertical cross-sectional structure of the clamping part of the present invention;
[0077] Figure 13 This is an exploded disassembly diagram of the outer support unit and the inner clamping unit of the present invention;
[0078] Figure 14 This is a schematic diagram of the fixing component structure with auxiliary fixing unit of the present invention;
[0079] Figure 15 This is a schematic diagram showing the positional relationship between the auxiliary fixing unit and the fixing components of the present invention;
[0080] Figure 16 For the present invention Figure 15 A schematic diagram showing the positional relationship between the auxiliary fixing unit and the fixing components when no container is added;
[0081] Figure 17 For the present invention Figure 16 A top-down view of the structure;
[0082] Figure 18 For the present invention Figure 16 A front view structural diagram;
[0083] Figure 19 For the present invention Figure 16 A magnified schematic diagram of the structure at point I;
[0084] Figure 20 For the present invention Figure 17 A magnified schematic diagram of the structure at point J;
[0085] Figure 21 For the present invention Figure 18 A magnified schematic diagram of the structure at point K.
[0086] Explanation of reference numerals in the attached figures
[0087] 1. Workbench; 11. Control panel; 12. Support plate; 13. Through slot;
[0088] 2. Supporting shell;
[0089] 3. Drive assembly; 31. Drive motor; 32. Drive shaft; 33. Connecting block;
[0090] 4. Fixing components; 41. Mounting housing;
[0091] 5. Fixing part; 51. Limiting cover; 52. Connecting arc rod; 53. Support rod; 54. Rotating shell; 55. First telescopic rod; 56. Clamping arc plate;
[0092] 6. Counterweight; 61. Synchronizing rod; 62. Counterweight block; 63. Limiting component; 64. Second telescopic rod; 65. Connecting rod;
[0093] 7. Auxiliary fixing unit; 71. Transmission block; 72. Fixing rod; 73. Slider; 74. Horizontal guide rail; 75. Connecting vertical rod; 76. Auxiliary clamping plate; 77. Transmission roller;
[0094] 8. Container. Detailed Implementation
[0095] The present invention will be further illustrated by way of embodiments below, but the present invention is not limited to the scope of the embodiments.
[0096] like Figure 1 and Figure 2 As shown, a reagent mixing processor for medical immunological testing includes a workbench 1, and a drive unit is provided inside the workbench 1. The drive unit passes through the top side wall of the workbench 1 housing and is biasedly connected to the support shell 2.
[0097] The drive unit drives the bearing shell 2 to swing in a circular motion in the horizontal direction;
[0098] The bearing shell 2 is located on the top of the workbench 1 and overlaps with the annular bearing plate 12 on the top of the workbench 1 shell. The bearing plate 12 is used to support the bearing shell 2, and the drive unit does not bear the supporting role.
[0099] A fixing component 4 for fixing the reagent container 8, wherein there are a plurality of fixing components 4 and the plurality of fixing components 4 are evenly distributed on the carrier shell 2;
[0100] The fixing component 4 is clamped in the middle or upper part of the container 8, and as the supporting shell 2 swings, the bottom of the container 8 swings in a circular shape with the clamping point as the center.
[0101] The workbench 1 is equipped with a control panel 11, which is used to control the start and speed of the drive motor 31. The connection method between the control panel 11 and the drive motor 31, as well as the power supply method of the drive motor 31, are all existing technologies and will not be described in detail in this technical solution.
[0102] Furthermore, the models of the drive motor 31 and the control panel 11 can be selected from commonly used models of mixing equipment.
[0103] The drive unit drives the carrier shell 2 to swing in a circular motion in the horizontal direction, thereby causing the container 8 held by the fixing component 4 to swing, with its bottom swinging in a circular motion. This allows the reagents and samples to be mixed evenly without prolonged stirring.
[0104] Example 1
[0105] like Figure 3 and 4 As shown, the drive unit includes a drive motor 31, the output end of the drive motor 31 is arranged facing upward, and a drive shaft 32 in the shape of a "Z" is fixed on the output end of the drive motor 31.
[0106] The top of the drive shaft 32 passes sequentially through the through groove 13 on the top of the workbench 1 housing and the inner ring of the bearing ring, and is fixedly connected to the circular connecting block 33 at the bottom of the bearing shell 2. The connecting block 33 is located in the inner ring cavity of the bearing ring.
[0107] The connecting block 33 is fixed at an off-center position at the bottom of the bearing shell 2, and the drive motor 31 is fixed to the side wall at the bottom of the inner cavity of the workbench 1 by an "L"-shaped connector.
[0108] The drive motor 31 drives the carrier shell 2 to swing in a circular trajectory via the drive shaft 32.
[0109] Example 2
[0110] like Figure 5-13 As shown, the fixing component 4 includes a mounting shell 41, and a clamping part for clamping and fixing the container 8 is provided above the inner cavity of the mounting shell 41.
[0111] The clamping part includes an outer support unit and an inner clamping unit, wherein the inner clamping unit clamps and fixes the container 8;
[0112] The inner clamping unit is fitted inside the outer support unit, and the inner clamping unit rotates inside the outer support unit. The outer support unit is fixedly mounted on the shell 41.
[0113] The inner clamping unit clamps the container 8, and the inner clamping unit can rotate inside the outer supporting unit, thus providing a structural basis for the swinging of the container 8.
[0114] Furthermore, the outer surface of the inner clamping unit and the outward extension surface of the outer surface form a complete spherical structure, and the inner cavity surface of the outer support unit and the outward extension surface of the inner cavity surface form a complete spherical structure. That is, the contact surface between the inner clamping unit and the outer support unit is a spherical structure, and a universal rotating connection structure is formed between the inner clamping unit and the outer support unit to facilitate the clamping part to clamp the container 8 and swing in the horizontal direction.
[0115] The outer support unit includes multiple limiting covers 51 arranged in a ring array. Two adjacent limiting covers 51 are connected to each other by connecting arc rods 52. At least two limiting covers 51 are fixed with support rods 53 on their outer walls. The support rods 53 are fixed to the inner wall of the mounting shell 41.
[0116] The inner walls of all the limiting covers 51 together form a spherical structure, and the limiting covers 51 are attached to the outer wall of the inner clamping unit.
[0117] The inner clamping unit rotates within the spherical cavity enclosed by all the limiting outer covers 51.
[0118] Specifically, the inner clamping unit includes a rotating shell 54 with an overall annular structure and a spherical outer wall, the outer wall of which is fitted with the inner wall of the limiting cover 51;
[0119] A clamping member is disposed in the inner cavity of the rotating shell 54, clamping the surface of the container 8, and the container 8 passes through the rotating shell 54.
[0120] The clamping member clamps the container 8, and the clamping member rotates with the rotating shell 54 inside the spherical cavity enclosed by the limiting outer cover 51.
[0121] Specifically, the clamping member includes two symmetrically arranged clamping arc plates 56, which are connected to the inner wall of the rotating shell 54 via a first telescopic rod 55 arranged in the horizontal direction.
[0122] The line connecting the two first telescopic rods 55 passes through the center of the rotating shell 54 and the center point between the two clamping arc plates 56.
[0123] A first spring is sleeved on the surface of the first telescopic rod 55, and the container 8 is held by the elastic force provided by the first spring.
[0124] The container 8 containing reagents and samples is inserted between two clamping arc plates 56. The two clamping arc plates 56 are pushed outward, so that the clamping arc plates 56 are clamped in the middle or upper part of the container 8. At this time, the first spring is deformed, and the elastic force generated by the potential energy of the first spring to recover the deformation clamps the container 8.
[0125] A clamping layer made of soft rubber can be bonded to the clamping arc plate 56 to increase the static friction between the clamping arc plate 56 and the container 8.
[0126] If necessary, the corresponding stopper can be placed at the inlet of container 8 during mixing.
[0127] When the carrier shell 2 swings, the rotating shell 54 holding the container 8 moves and rotates in the inner cavity of the limiting outer cover 51. Since it is held in the middle or upper part of the container 8, the bottom of the container 8 swings in a circular motion.
[0128] An optimized technical solution in this application further includes a counterweight 6 that facilitates the follow-up movement of the clamping part. The counterweight 6 includes two symmetrically arranged "L"-shaped synchronous rods 61, such as... Figure 10 As shown, the vertical portions of the two synchronizing rods 61 are distributed along both sides of the clamped container 8, and the vertical portions extend to the bottom of the container 8. The horizontal portions of the two synchronizing rods 61 are located at the bottom of the container 8 and are both connected to the top of the counterweight block 62. The counterweight block 62 is located directly below the two clamping arc plates 56.
[0129] The top of the synchronizing rod 61 is fixed to the telescopic end of the first telescopic rod 55;
[0130] Furthermore, the horizontal portion of the synchronizing rod 61 is extendable, meaning that the horizontal portion of the synchronizing rod 61 and the first telescopic rod 55 extend and retract synchronously.
[0131] The counterweight 62 can lower the center of gravity of the fixing part 5 and increase the center of gravity of the bottom of the container 8 so that it can swing better with the bearing shell 2, which is beneficial to the clamping part clamping the container 8.
[0132] The counterweight 62 is made of a material, and a limiting member 63 that can generate a ring magnetic field is provided around the swing trajectory of the counterweight 62. The limiting member 63 is fixed on the inner wall of the mounting shell 41. The magnetic field generated by the limiting member 63 and the counterweight 62 repel each other. Through the mutual repulsion of magnetic force, the diameter of the circular trajectory of the counterweight 62 when the bottom swings can be avoided to be too large, that is, the swing amplitude of the container 8 is avoided to be too large.
[0133] The limiting component 63 is preferably an electromagnet, which can adjust the magnitude of the magnetic field.
[0134] Example 3
[0135] like Figure 14-21 As shown, it also includes two symmetrically arranged auxiliary fixing units 7, which are distributed on both sides of the two synchronizing rods 61;
[0136] The auxiliary fixing unit 7 includes a driving component and an auxiliary component for clamping the container 8. The driving component is disposed on the retractable area of the vertical portion of the synchronizing rod 61, and the driving component pushes the auxiliary component to clamp the surface of the container 8 as the retractable area of the vertical portion of the synchronizing rod 61 extends.
[0137] like Figure 18 As shown, the telescopic area of the vertical portion of the synchronizing rod 61 is a second telescopic rod 64 arranged vertically, and the second telescopic rod 64 replaces the middle area of the original vertical portion of the synchronizing rod 61.
[0138] The driving component is a self-rotating transmission roller 77, which is installed at the bottom end of the second telescopic rod 64. The downward (outward) movement of the transmission roller 77 is connected to the auxiliary component.
[0139] The auxiliary component includes a transmission block 71, the top of which is provided with a transmission inclined surface, which overlaps with the transmission roller 77, and the transmission block 71 is slidable in the horizontal direction.
[0140] An auxiliary clamping plate 76 for clamping the container 8 is fixed on the transmission block 71. The auxiliary clamping plate 76 and the transmission inclined surface are located on both sides of the transmission block 71.
[0141] Both sides of the transmission block 71 are provided with connecting parts. Each connecting part includes a fixed rod 72 with an "L"-shaped structure. A slider 73 is fixed to the top of the fixed rod 72. The slider 73 is slidably connected to a horizontal guide rail 74 arranged in the horizontal direction. The horizontal guide rail 74 is arranged parallel to the first telescopic rod 55. The top of the horizontal guide rail 74 is connected to the telescopic end of the first telescopic rod 55 through a connecting vertical rod 75, and the connecting vertical rod 75 is located inside the second telescopic rod 64.
[0142] The surface of the second telescopic rod 64 is fitted with a second spring, which maintains the length of the second telescopic rod 64 without providing additional potential energy support.
[0143] One end of the slider 73 is connected to the third spring, and the other end of the third spring is fixed on the guide rail. When the clamping arc plate 56 is clamped on the surface of the container 8 under normal conditions, the auxiliary clamping plate 76 does not contact the surface of the container 8.
[0144] The top and bottom of the second telescopic rod 64 are connected by a "Z"-shaped connecting rod 65 and a synchronizing rod 61, increasing the distance between the second telescopic rod 64 and the connecting vertical rod 75 to facilitate the installation of the transmission block 71.
[0145] When the second spring is in its normal state, the third spring does not deform.
[0146] When the bottom of container 8 swings in a circular trajectory, the counterweight 62 also swings accordingly. The second telescopic rod 64, which is indirectly connected to the counterweight 62, is stretched. The telescopic end of the stretched second telescopic rod 64 moves outward, thereby driving the transmission roller 77 to move synchronously. The moving roller pushes the transmission block 71 to one side of container 8 through the transmission inclined plane until the auxiliary clamping plate 76 on the transmission block 71 clamps the container 8, completing the auxiliary clamping of container 8.
[0147] The faster the container 8 swings, the greater the clamping force provided by the auxiliary fixing unit 7, which can further improve the fixing effect on the container 8.
[0148] The auxiliary fixing unit 7 utilizes the synchronous swing of the counterweight 62 when the bottom of the container 8 swings to automatically drive the auxiliary clamping structure through mechanical linkage, without the need for an additional power source, and the structure is self-driven.
[0149] This invention is not limited to the embodiments described above. Any changes in shape or structure fall within the protection scope of this invention. The protection scope of this invention is defined by the appended claims. Those skilled in the art can make various changes or modifications to these embodiments without departing from the principles and essence of this invention, but all such changes and modifications fall within the protection scope of this invention.
Claims
1. A reagent mixing processor for medical immunological testing, comprising a workbench (1), wherein a drive unit is disposed inside the workbench (1), the drive unit passing through the top sidewall of the workbench (1) housing and being biasedly connected to a support shell (2), characterized in that: The drive unit drives the bearing shell (2) to swing in a circular motion in the horizontal direction; The bearing shell (2) is located on top of the workbench (1) and overlaps with the annular bearing plate (12) on the top of the workbench (1) shell; Fixing components (4) for fixing reagent containers (8), there are a plurality of fixing components (4), and the plurality of fixing components (4) are evenly distributed on the carrier shell (2); The fixing component (4) is clamped in the middle or upper part of the container (8), and as the supporting shell (2) swings, the bottom of the container (8) swings in a circular motion around the clamping point. The fixing component (4) includes a mounting shell (41), and a clamping part for clamping and fixing the container (8) is provided above the inner cavity of the mounting shell. The clamping part includes an outer support unit and an inner clamping unit, wherein the inner clamping unit clamps and fixes the container (8). The inner clamping unit is fitted inside the outer support unit, and the inner clamping unit rotates inside the outer support unit. The outer support unit is fixed on the mounting shell (41). The outer surface of the inner clamping unit and the outward extension of the outer surface form a complete spherical structure, and the inner cavity surface of the outer support unit and the outward extension of the inner cavity surface form a complete spherical structure. The outer support unit includes multiple limiting covers (51) arranged in a ring array. Two adjacent limiting covers (51) are connected to each other by connecting arc rods (52). At least two limiting covers (51) have support rods (53) fixed on their outer walls. The support rods (53) are fixed on the inner wall of the mounting shell (41). The inner walls of all the limiting covers (51) together form a spherical structure, and the limiting covers (51) are attached to the outer wall of the inner clamping unit. The inner clamping unit includes a rotating shell (54) with an overall ring structure and a spherical outer wall, and the outer wall of the rotating shell (54) is attached to the inner wall of the limiting cover (51); The clamping member is set in the inner cavity of the rotating shell (54), the clamping member clamps the surface of the container (8), and the container (8) passes through the rotating shell (54). The clamping member includes two symmetrically arranged clamping arc plates (56), which are connected to the inner wall of the rotating shell (54) via a first telescopic rod (55) arranged in the horizontal direction; A first spring is sleeved on the surface of the first telescopic rod (55), and the container (8) is clamped by the elastic force provided by the first spring. It also includes a counterweight (6) that facilitates the movement of the clamping part. The counterweight (6) includes two symmetrically arranged "L"-shaped synchronous rods (61). The vertical parts of the two synchronous rods (61) are distributed along both sides of the clamped container (8) and extend to the bottom of the container (8). The horizontal parts of the two synchronous rods (61) are located at the bottom of the container (8) and are both connected to the top of the counterweight block (62). The counterweight block (62) is located directly below the two clamping arc plates (56). The top of the synchronizing rod (61) is fixed to the telescopic end of the first telescopic rod (55); Furthermore, the horizontal part of the synchronizing rod (61) is telescopic, and the horizontal part of the synchronizing rod (61) and the first telescopic rod (55) telescopically extend and retract. A limiting member (63) that can generate a ring magnetic field is provided around the swing trajectory of the counterweight (62). The limiting member (63) is fixed on the inner wall of the mounting shell (41). The magnetic field generated by the limiting member (63) and the counterweight (62) repel each other to avoid the swing amplitude of the container (8) being too large.
2. The reagent mixing processor for medical immunoassay as described in claim 1, characterized in that: The drive unit includes a drive motor (31), the output end of the drive motor (31) is arranged facing upward, and a drive shaft (32) in the shape of a "Z" is fixed on the output end of the drive motor (31). The top of the drive shaft (32) passes through the through groove (13) at the top of the workbench (1) housing and the inner ring of the bearing ring in sequence, and is fixedly connected to the circular connecting block (33) at the bottom of the bearing shell (2). The connecting block (33) is located in the inner ring cavity of the bearing ring.
3. The reagent mixing processor for medical immunological testing as described in claim 2, characterized in that: The connecting block (33) is fixed at an off-center position at the bottom of the bearing shell (2), and the drive motor (31) is fixed to the side wall at the bottom of the inner cavity of the worktable (1) by an "L"-shaped connector.
4. The reagent mixing processor for medical immunoassay as described in claim 1, characterized in that: It also includes two symmetrically arranged auxiliary fixing units (7), which are distributed on both sides of the two synchronizing rods (61); The auxiliary fixing unit (7) includes a driving component and an auxiliary component for clamping the container (8). The driving component is located on the retractable area of the vertical portion of the synchronizing rod (61), and the driving component pushes the auxiliary component to clamp the container (8) as the retractable area of the vertical portion of the synchronizing rod (61) extends.
Citation Information
Patent Citations
Anticoagulation blood sampling test tube storage box for hematology department
CN115430477A
Blood routine examination device
CN213913469U