Lung targeted medicine atomization administration device with respiration triggering function

By using a respiratory-triggered lung-targeted drug nebulizer, which employs mechanical direction adjustment components and airflow sensors, drugs can be precisely guided to the lungs during the inhalation phase. This solves the problems of disordered drug diffusion and waste, and improves drug utilization and therapeutic efficacy.

CN121466432AInactive Publication Date: 2026-02-06JINAN THE THIRD HOSPITAL
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Patent Information

Application Number
CN202511740325.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-11-25
Publication Date
2026-02-06
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

Existing nebulized drug delivery devices cause drugs to diffuse disorderly in the respiratory tract, resulting in drug deposition in non-lesion areas, low drug utilization, and inability to synchronize with the patient's breathing, leading to drug waste and poor efficacy.

Method used

The lung-targeted drug delivery device with respiratory triggering uses a mechanical direction adjustment component consisting of a servo motor, gears, electric telescopic rods, and guide plates, combined with a differential pressure airflow sensor, to accurately guide the drug to the target area of ​​the lungs during the inhalation phase and automatically shut off during the exhalation phase, avoiding drug waste.

Benefits of technology

It significantly improves drug utilization and treatment efficacy, reduces drug waste, enhances the hygiene and safety of the device and user experience, and lowers production and maintenance costs.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention provides a lung targeted medicine atomization administration device with a respiration triggering function, and relates to the technical field of atomization administration devices. The lung targeted medicine atomizing and dosing device with the respiration triggering function comprises a shell, a medicine storage tank is fixedly connected to the upper end of the interior of the shell, a liquid discharging pipe is fixedly connected to the lower end of the medicine storage tank, an electromagnetic valve is arranged in the liquid discharging pipe, an atomizing cavity is fixedly connected to the lower end of the liquid discharging pipe, and the atomizing cavity is communicated with the medicine storage tank. A piezoelectric ceramic vibrator is arranged in the atomization cavity, the lower end of the atomization cavity is fixedly connected with a vertical ventilation pipe, and a micropore screen is arranged in a connecting opening of the vertical ventilation pipe and the atomization cavity. In the invention, the breathing triggering module is used for realizing inspiration and drug administration synchronously, and the precise mechanical direction adjusting assembly is combined, so that the drug beam can be actively and accurately guided to the target area of the lung, and the drug utilization rate and the treatment effect are remarkably improved.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of atomization administration device, in particular to a lung-targeted drug atomization administration device with breath triggering. BACKGROUND

[0002] At present, in the clinical treatment of lung diseases (such as asthma, chronic obstructive pulmonary disease, etc.), the atomization inhalation therapy is a widely used and effective drug administration method. The existing atomization administration device is mainly based on ultrasonic wave or compressed air (mesh type) technology principle, and its core function is to convert liquid medicine into micron-sized aerosol, which is delivered to the respiratory tract and lung through the respiratory movement of the patient. These traditional devices have been relatively mature in clinical application, and have provided basic treatment support for countless patients, and constitute an important means of modern respiratory system disease treatment.

[0003] However, the existing technology has inherent defects that are difficult to overcome, which seriously restricts the improvement of treatment effect. First, the drug mist generated is in a disordered diffusion state in the respiratory tract, a large amount of drug is deposited in the non-lesion area such as the oral cavity and throat, and the proportion of the drug that really reaches the lung target area is extremely low, causing serious drug waste and efficacy discount. Secondly, the existing device cannot be synchronized with the respiratory rhythm of the patient, and still continuously sprays drug mist during the exhalation phase, resulting in the drug being directly exhaled, further aggravating the waste.

[0004] Therefore, the skilled in the art provides a lung-targeted drug atomization administration device with breath triggering to solve the problems raised in the background art. SUMMARY

[0005] In view of the shortcomings of the prior art, the present application provides a lung-targeted drug atomization administration device with breath triggering, which solves the problems of poor drug targeting, low utilization rate, and drug waste and poor efficacy caused by the inability to synchronize with the patient's breathing of the traditional atomizer.

[0006] To achieve the above purpose, the present application is realized by the following technical scheme: The lung-targeted drug atomization administration device with breath triggering comprises a shell, a medicine storage tank is fixedly connected to the upper end of the inside of the shell, a lower liquid pipe is fixedly connected to the lower end of the medicine storage tank, an electromagnetic valve is arranged in the inside of the lower liquid pipe, an atomization chamber is fixedly connected to the lower end of the lower liquid pipe, a piezoelectric ceramic vibrator is arranged in the inside of the atomization chamber, a vertical ventilation pipe is fixedly connected to the lower end of the atomization chamber, and a microporous screen is arranged in the connecting port of the vertical ventilation pipe and the atomization chamber. The vertical air pipe is fixedly connected with a horizontal air pipe on one side, the horizontal air pipe is rotatably connected with a rotating air pipe through a rotating groove formed in the outer wall of the horizontal air pipe, the rotating air pipe is externally sleeved with a gear ring, the lower end of the vertical air pipe is provided with a servo motor, the output end of the servo motor is sleeved with a gear one, and the gear one is in meshing connection with the gear ring; The lower end of the rotating air pipe is provided with an electric telescopic rod, the output end of the electric telescopic rod is fixedly connected with a gear rack, the outlet of the rotating air pipe is rotatably connected with a plurality of guide plates, the upper and lower ends of the plurality of guide plates are rotatably connected with the rotating air pipe through rotating rods, the plurality of rotating rods at the lower end are externally sleeved with a gear two, and the plurality of gear twos are in meshing connection with the gear rack; The lower end of the inner part of the shell is fixedly connected with a partition plate, the lower end of the partition plate is provided with an auxiliary air pump, a main circuit board and a storage battery, one side of the shell is fixedly connected with an execution head, and the inner part of the execution head is provided with two differential pressure air flow sensors; Through the above technical scheme, the inspiration synchronous drug delivery is realized through the breath trigger module, and the precise mechanical direction adjusting assembly is combined, so that the drug beam can be actively and accurately guided to the target area of the lung, and the drug utilization rate and the treatment effect are significantly improved.

[0007] Further, the outer wall of the rotating air pipe is fixedly connected with a guide rail, and the gear rack is fixedly connected with a sliding block in sliding cooperation with the guide rail. Through the above technical scheme, accurate guidance and support are provided for the reciprocating motion of the gear rack, so that the driving force of the electric telescopic rod can be stably transmitted to the gear two, thereby ensuring the synchronization and reliability of the opening and closing actions of the plurality of guide plates, and preventing the jamming or deviation in the motion process.

[0008] Further, the distal end of the execution head is detachably connected with a mouthpiece. Through the above technical scheme, the mouthpiece can be conveniently detached, replaced or disinfected, the cross-infection risk between different patients or multiple uses of the same patient is effectively avoided, and the sanitary safety and use convenience of the device are improved.

[0009] Further, the gas outlet of the auxiliary air pump is connected with the inlet of the horizontal air pipe through an independent air pipe. Through the above technical scheme, the separate design of the auxiliary air flow and the main drug path is realized, the stable supply of the auxiliary air flow is ensured, the controllable conveying power is provided for the drug mist, the interference of vibration or heat generated by the air pump on the atomization core component is avoided, and the stability and atomization quality of the whole system are improved.

[0010] Further, the upper end of the shell is screwed with an upper shell, and the lower end of the shell is screwed with a lower shell. Through the technical scheme, the shell is extremely convenient to disassemble and assemble, is convenient to assemble in the production process and maintain, overhaul and part replacement in the later use process, and greatly reduces the production and maintenance cost.

[0011] Further, one side of the shell is fixedly connected with a touch screen for user interaction. Through the technical scheme, an intuitive and intelligent operation interface is provided for the user, the user can conveniently set treatment parameters and monitor equipment states, the operation process is greatly simplified, and the intelligent level and user experience of the device are improved.

[0012] Further, the shell is provided with an air inlet grille on one side. Through the technical scheme, necessary heat dissipation air ducts are provided for electronic elements and auxiliary air pumps in the shell, heat generated during equipment operation is effectively reduced, components are ensured to stably work at suitable temperatures, and the service life of the device is prolonged.

[0013] The present application provides a lung-targeted drug aerosol delivery device with breath triggering. 1. The present application provides a lung-targeted drug aerosol delivery device with breath triggering, which comprises a direction adjusting assembly composed of a servo motor, a gear one, a gear ring, a rotating ventilation pipe, an electric telescopic rod, a gear rack, a gear two and a flow guide plate, which realizes active and accurate control of the direction of drug mist spraying, thereby accurately guiding the high-concentration drug beam to the preset target area of the lung, greatly improving the drug utilization rate and treatment effect.

[0014] 2. The present application provides a lung-targeted drug aerosol delivery device with breath triggering, which comprises a breath triggering module composed of two differential pressure air flow sensors arranged inside the execution head and electrically connected with the main circuit board, which realizes real-time monitoring and intelligent judgment of the patient's breathing phase, thereby only starting aerosolization and guidance during the inhalation phase and automatically shutting down during the exhalation phase, effectively avoiding drug waste and realizing intelligent and efficient synchronous drug delivery. BRIEF DESCRIPTION OF DRAWINGS

[0015] Figure 1 It is a perspective view of the whole shell of the present application. Figure 2 It is an expanded schematic view of the shell, upper shell and lower shell of the present application. Figure 3 It is a sectional view of the shell of the present application. Figure 4 It is a front perspective view of the vertical ventilation pipe and the horizontal ventilation pipe of the present application. Figure 5 It is a sectional view of the vertical ventilation pipe and the horizontal ventilation pipe of the present application. Figure 6The following are side axonometric views of the vertical and horizontal vent pipes of the present invention; Figure 7 This is a schematic diagram of the rotating vent pipe and guide plate of the present invention.

[0016] Explanation of reference numerals in the attached figures: 1. Housing; 2. Upper housing; 3. Lower housing; 4. Medicine storage tank; 5. Lower liquid pipe; 6. Solenoid valve; 7. Atomizing chamber; 8. Piezoelectric ceramic vibrator; 9. Microporous screen; 10. Vertical air pipe; 11. Horizontal air pipe; 12. Rotating groove; 13. Rotating air pipe; 14. Gear ring; 15. Servo motor; 16. Gear one; 17. Electric telescopic rod; 18. Rack; 19. Guide plate; 20. Gear two; 21. Slider; 22. Guide rail; 23. Actuator head; 24. Differential pressure airflow sensor; 25. Mouthpiece; 26. Partition; 27. Auxiliary air pump; 28. Main circuit board; 29. ​​Battery; 30. Touch screen; 31. Air intake grille. Detailed Implementation

[0017] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0018] Example 1: like Figures 1-7 As shown, this embodiment of the invention provides a lung-targeted drug nebulization delivery device with respiratory triggering, including a housing 1. A drug storage tank 4 is fixedly connected to the upper end of the housing 1. A liquid lowering pipe 5 is fixedly connected to the lower end of the drug storage tank 4. An electromagnetic valve 6 is installed inside the liquid lowering pipe 5. An nebulization chamber 7 is fixedly connected to the lower end of the liquid lowering pipe 5. A piezoelectric ceramic vibrator 8 is installed inside the nebulization chamber 7. A vertical air passage 10 is fixedly connected to the lower end of the nebulization chamber 7. A microporous screen 9 is installed inside the connection port between the vertical air passage 10 and the nebulization chamber 7. A horizontal air pipe 11 is fixedly connected to one side of the vertical air pipe 10. The horizontal air pipe 11 is rotatably connected to a rotating air pipe 13 through a rotating groove 12 opened on the outer wall. A toothed ring 14 is sleeved on the outside of the rotating air pipe 13. A servo motor 15 is provided at the lower end of the vertical air pipe 10. A gear 16 is sleeved on the output end of the servo motor 15. The gear 16 meshes with the toothed ring 14. An electric telescopic rod 17 is provided at the lower end of the rotating vent pipe 13. A rack 18 is fixedly connected to the output end of the electric telescopic rod 17. Multiple guide plates 19 are rotatably connected to the outlet of the rotating vent pipe 13. The upper and lower ends of the multiple guide plates 19 are rotatably connected to the rotating vent pipe 13 through rotating rods. Gear 20 is sleeved on the outside of the multiple rotating rods at the lower end. The multiple gear 20 meshes with the rack 18. A partition 26 is fixedly connected to the lower end of the interior of the housing 1. An auxiliary air pump 27, a main circuit board 28, and a battery 29 are installed at the lower end of the partition 26. An actuator head 23 is fixedly connected to one side of the housing 1. Two differential pressure airflow sensors 24 are installed inside the actuator head 23. The respiratory trigger module enables simultaneous drug delivery during inhalation, and combined with a precise mechanical direction adjustment component, it can actively and accurately guide the drug beam to the target area of ​​the lungs, significantly improving drug utilization and treatment efficacy.

[0019] A guide rail 22 is fixedly connected to the outer wall of the rotating ventilation tube 13. A slider 21 that slides with the guide rail 22 is fixedly connected to the rack 18, providing precise guidance and support for the reciprocating motion of the rack 18. This ensures that the driving force of the electric telescopic rod 17 can be stably transmitted to the gear 20, thereby ensuring the synchronicity and reliability of the opening and closing actions of multiple guide plates 19 and preventing jamming or deviation during the movement. The end of the actuator 23 is detachably connected to a mouthpiece 25, which allows for easy disassembly, replacement, or disinfection of the mouthpiece 25. This effectively avoids the risk of cross-infection between different patients or multiple uses by the same patient, improving the hygiene and safety of the device and its ease of use. The outlet of the auxiliary air pump 27 is connected to the inlet of the horizontal ventilation tube 11 through an independent air pipe, realizing a separate design between the auxiliary airflow and the main drug path. This ensures a stable supply of auxiliary airflow, provides controllable delivery power for the drug mist, and avoids gas... The vibration or heat generated by the pump operation reduces interference with the core atomization components, improving the overall system stability and atomization quality. The upper shell 2 is threaded at the top of the housing 1, and the lower shell 3 is threaded at the bottom, making the assembly and disassembly of the housing 1 extremely convenient. This facilitates assembly during production and maintenance, repair, and parts replacement during later use, significantly reducing production and maintenance costs. A touchscreen 30 for user interaction is fixedly connected to one side of the housing 1, providing users with an intuitive and intelligent operating interface. Users can easily set treatment parameters and monitor equipment status, greatly simplifying the operation process and improving the device's intelligence and user experience. An air intake grille 31 is provided on one side of the housing 1, providing necessary cooling channels for the internal electronic components and auxiliary air pump 27, effectively reducing the heat generated during equipment operation, ensuring stable operation of all components at suitable temperatures, and extending the device's service life.

[0020] Working principle: First, during the system preparation phase, the user sets treatment parameters via the touchscreen 30 fixed to one side of the housing 1, such as targeting the upper left lobe of the lung. The main circuit board 28 receives and stores these instructions. At this time, the liquid medicine stored in the drug reservoir 4 flows to the lower liquid pipe 5 due to gravity, but is temporarily prevented from flowing out by the closed solenoid valve 6, and the entire device is in standby mode.

[0021] When the patient takes the mouthpiece 25 at the end of the actuator head 23 into their mouth and begins to breathe, the respiratory monitoring and triggering phase is initiated. Two differential pressure airflow sensors 24 integrated inside the actuator head 23 monitor pressure changes within the breathing channel in real time. When the patient begins to inhale, the sensors detect a specific positive pressure difference and immediately send this "inhalation" signal to the main circuit board 28. The built-in algorithm on the main circuit board 28 confirms the start of inhalation, instantly generates a trigger command, and initiates the nebulization and guided execution phase.

[0022] Upon receiving the trigger signal, the main circuit board 28 simultaneously executes several precision operations: First, it controls the opening of the solenoid valve 6, allowing the liquid medicine to flow into the atomization chamber 7, while simultaneously driving the piezoelectric ceramic vibrator 8 to vibrate at high frequency, causing the liquid medicine to pass through the microporous screen 9 to form uniform drug mist particles; Second, it first drives the electric telescopic rod 17 to extend, pushing the rack 18 to slide along the guide rail 22, thereby driving multiple gears 20 to rotate synchronously, precisely adjusting the deflection angle of the guide plate 19 to control the blowing angle of the drug mist beam; Subsequently, according to the preset target, it drives the servo motor 15 to rotate, and through the meshing transmission of gear 16 and gear ring 14, drives the entire rotating ventilation tube 13, which has been set at a certain angle, to rotate, so that its final blowing position is precisely aligned with the target area of ​​the lungs. At the same time, the auxiliary air pump 27 located in the lower layer of the housing 1 starts, injecting clean air into the airflow channel through an independent air tube, providing additional delivery power for the drug mist.

[0023] Finally, during the drug delivery phase, the high-concentration drug mist, propelled by the auxiliary airflow, forms a concentrated jet that sequentially passes through the vertical airway 10, the horizontal airway 11, and the oriented rotating airway 13, before being ejected at high speed from the precisely angled guide plate 19. This mist is then accurately inhaled by the patient and directly reaches the lung lesions. When the sensor detects an exhalation signal, the main circuit board 28 immediately instructs all components to reset, closing the solenoid valve 6 and the guide plate 19, awaiting the next inhalation trigger. This cycle continues until the treatment is complete.

[0024] The following points should be noted in this article: 1. The accompanying drawings of the embodiments disclosed herein only relate to the structures involved in the embodiments disclosed herein; other structures can be referred to in a general design.

[0025] 2. Where there is no conflict, the embodiments of this disclosure and the features in the embodiments can be combined with each other to obtain new embodiments.

[0026] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

Claims

1. A lung-targeted drug nebulization delivery device with respiratory triggering, comprising a housing (1), characterized in that: The upper end of the shell (1) is fixedly connected to a medicine storage tank (4), the lower end of the medicine storage tank (4) is fixedly connected to a liquid drain pipe (5), the lower end of the liquid drain pipe (5) is provided with a solenoid valve (6), the lower end of the liquid drain pipe (5) is fixedly connected to an atomizing chamber (7), the atomizing chamber (7) is provided with a piezoelectric ceramic vibrator (8), the lower end of the atomizing chamber (7) is fixedly connected to a vertical air pipe (10), and the connection port between the vertical air pipe (10) and the atomizing chamber (7) is provided with a microporous screen (9). A horizontal air pipe (11) is fixedly connected to one side of the vertical air pipe (10). The horizontal air pipe (11) is rotatably connected to a rotating air pipe (13) through a rotating groove (12) opened on the outer wall. A toothed ring (14) is sleeved on the outside of the rotating air pipe (13). A servo motor (15) is provided at the lower end of the vertical air pipe (10). A gear (16) is sleeved at the output end of the servo motor (15). The gear (16) meshes with the toothed ring (14). The lower end of the rotating vent pipe (13) is provided with an electric telescopic rod (17), the output end of the electric telescopic rod (17) is fixedly connected with a rack (18), and multiple guide plates (19) are rotatably connected at the outlet of the rotating vent pipe (13). The upper and lower ends of the multiple guide plates (19) are rotatably connected to the rotating vent pipe (13) through rotating rods, and gears (20) are sleeved on the outside of the multiple rotating rods at the lower end. The multiple gears (20) are meshed with the rack (18). A partition (26) is fixedly connected to the lower end of the housing (1). An auxiliary air pump (27), a main circuit board (28), and a storage battery (29) are provided at the lower end of the partition (26). An actuator (23) is fixedly connected to one side of the housing (1). Two differential pressure airflow sensors (24) are provided inside the actuator (23).

2. The lung-targeted drug nebulization device with respiratory triggering according to claim 1, characterized in that: A guide rail (22) is fixedly connected to the outer wall of the rotating vent pipe (13), and a slider (21) that slides with the guide rail (22) is fixedly connected to the rack (18).

3. The lung-targeted drug nebulization device with respiratory triggering according to claim 1, characterized in that: The mouthpiece (25) is detachably connected to the end of the execution head (23).

4. The lung-targeted drug nebulization device with respiratory triggering according to claim 1, characterized in that: The outlet of the auxiliary air pump (27) is connected to the inlet of the horizontal air pipe (11) through an independent air pipe.

5. The lung-targeted drug nebulization device with respiratory triggering according to claim 1, characterized in that: The upper end of the housing (1) is threaded with an upper shell (2), and the lower end of the housing (1) is threaded with a lower shell (3).

6. The lung-targeted drug nebulization device with respiratory triggering according to claim 1, characterized in that: A touch screen (30) for user interaction is fixedly connected to one side of the housing (1).

7. The lung-targeted drug nebulization device with respiratory triggering according to claim 1, characterized in that: An air intake grille (31) is provided on one side of the housing (1).