Stomach sampling device based on obdurability biocompatible hydrogel film

By combining a tough, biocompatible hydrogel membrane with a magnetically controlled capsule, gastric cell sampling without anesthesia and with minimal trauma is achieved. This solves the problems of insufficient mechanical strength, poor biocompatibility, and insufficient sampling and recovery accuracy in existing technologies, thereby improving sampling accuracy and safety.

CN121489546APending Publication Date: 2026-02-10CHANGZHOU NAMAX MATERIAL TECH CO LTD
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Patent Information

Application Number
CN202511787799.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-12-01
Publication Date
2026-02-10

AI Technical Summary

Technical Problem

Existing gastric sampling techniques suffer from insufficient mechanical strength, poor biocompatibility, inadequate sampling and recovery accuracy, and a lack of stable fixation structures, leading to mechanical damage, sample loss, cell loss, and low operational safety.

Method used

A sampling device based on a tough, biocompatible hydrogel membrane is used, combined with a magnetically controlled capsule to achieve real-time visualization and targeted positioning. By expanding the hydrogel membrane and retrieving it with a traction wire, a camera, a wireless transmission module, and an illumination source are integrated to achieve gastric cell sampling without anesthesia and with minimal trauma.

Benefits of technology

It improves the accuracy and success rate of sampling, reduces mechanical damage and psychological stress, ensures sample quality, and achieves safe, reliable, and controllable recovery.

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Abstract

The invention belongs to the technical field of medical apparatus and instruments, and discloses a stomach sampling device based on a obdurability biocompatible hydrogel film, which comprises an expandable sampling cap and an in vitro traction device, the sampling cap is a closed cavity formed by a high-toughness hydrogel film, and water-absorbing particles and a magnetic control capsule are packaged in the hydrogel film; the in-vitro traction device comprises a traction line and an external oral fixing card, one end of the traction line is fixed inside the sampling cap in an embedding, knotting or anchoring manner, and the other end of the traction line is connected with the external oral fixing card. The whole process does not need intubation anesthesia, physiological pain and psychological fear of a patient are greatly reduced, the surface of the expanded hydrogel sphere is smooth and soft, the discomfort of the expanded hydrogel sphere passing through the esophagus during recovery is far lower than that of traditional gastric sponge, the compliance of the patient is remarkably improved, and the magnetic control capsule and an external magnetic control system are combined. Due to the real-time visualization and active navigation functions, the sampling accuracy and the cell acquisition rate are greatly improved.
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