Ion probe based on 2-(2-hydroxyphenyl) benzothiazole and synthesis method and application thereof

By combining the ion probe [DBU-HBT] based on 2-(2-hydroxybenzyl)benzothiazole with agarose hydrogel, the problem of loading poorly water-soluble probes in hydrogels is solved, enabling rapid, sensitive, and portable detection of beverage pH with obvious fluorescence signals, suitable for on-site detection.

CN121930188BActive Publication Date: 2026-06-16ZHEJIANG UNIV OF TECH

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
ZHEJIANG UNIV OF TECH
Filing Date
2026-03-27
Publication Date
2026-06-16

AI Technical Summary

Technical Problem

Traditional pH detection methods cannot achieve rapid detection of pH in beverages, and probes with poor water solubility have low loading efficiency and poor stability in hydrogels, which limits the selection of functional probes for hydrogels.

Method used

An ion probe based on 2-(2-hydroxybenzene)benzothiazole [DBU-HBT] was used. By mixing it with an aqueous solution of agarose and an N,N-dimethylformamide solution to form a hydrogel, the aggregation-induced chiral effect of the hydrogel was utilized to solve the aggregation-induced effect of the hydrogel. The fluorescence was quenched in the acidic solution, enabling rapid and sensitive detection.

🎯Benefits of technology

It enables rapid, sensitive, and portable detection of pH in beverages, with a clear fluorescence signal, making it suitable for on-site testing and solving the problem of loading probes with poor water solubility in hydrogels.

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Abstract

The application discloses an ion probe based on 2-(2-hydroxyphenyl) benzothiazole and a synthesis method and application thereof; the ion probe is abbreviated as [DBU-HBT]; a DMF solution of [DBU-HBT] is mixed with an aqueous agarose solution, and a hydrogel is formed by standing, so that the loading problem of water-insoluble probes in the hydrogel is solved, the aggregation-induced effect of the probes is retained, the demand of a portable device is met, and a new idea is provided for on-site detection of the pH of drinks in the environment.
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