Nourishing and repairing body wash and preparation method thereof

Abstract

The invention relates to the technical field of cosmetics, in particular to nourishing and repairing body wash and a preparation method thereof.The nourishing and repairing body wash is prepared from, by mass, 5%-7% of compound amino acid, 8%-10% of sodium cocoyl apple amino acid, 4%-6% of sea buckthorn fruit oil compound microcapsules and the like, and the balance deionized water. The compound microcapsule is of a double-layer structure, an outer-layer core material contains ceramide NP and phytosterol, an inner-layer core material contains sea buckthorn fruit oil and vitamin E, a wall material is beta-cyclodextrin, and the compound microcapsule is prepared through a step-by-step embedding method. The compound amino acid is formed by compounding serine, glycine and alanine according to a specific proportion. Through sequential release of the double-layer microcapsules and the synergistic effect of multiple components, the skin barrier repairing and moisturizing functions are achieved, the stability is excellent, and the skin physiological needs are gently met.

Description

Technical Field

[0001] This application relates to the field of cosmetic technology, specifically to a nourishing and repairing shower gel and its preparation method. Background Technology

[0002] In the personal care industry, amino acid-based body washes have become the mainstream choice for people with dry and sensitive skin due to their gentle and non-irritating properties. However, existing amino acid body washes generally suffer from core technical challenges: First, there is an imbalance between cleansing and nourishing effects. Most products focus only on the gentle cleansing properties of amino acid surfactants, neglecting the barrier repair and long-lasting moisturizing needs of dry skin. After cleansing, skin may feel tight, dry, or even flaky, failing to meet the deep nourishing needs of dry skin in daily care. Second, some products add high concentrations of emulsifiers and preservatives to optimize texture or extend shelf life, or the pH value of the formula deviates from the skin's physiological range, easily irritating the skin barrier and increasing the risk of redness, dryness, and itching for sensitive skin. Therefore, developing a moisturizing body wash that combines gentle cleansing and highly effective repair functions, with a stable and safe formula, has become a pressing technical problem that the industry needs to solve. Summary of the Invention

[0003] To address the shortcomings of existing technologies, this application provides a nourishing and repairing shower gel and its preparation method. A two-layer composite microcapsule containing an outer layer of ceramide NP / phytosterol, an inner layer of sea buckthorn fruit oil / vitamin E, and a β-cyclodextrin wall material is prepared via a stepwise encapsulation method. This microcapsule is then combined with a mild surfactant system of serine, glycine, alanine, and sodium cocoyl malic acid / polyglycerol-4 laurate, and prepared using a specific process. This results in barrier repair, moisturizing, and excellent stability and gentleness.

[0004] To achieve the above objectives, this application adopts the following technical solution:

[0005] In a first aspect, this application provides a nourishing and repairing body wash, comprising the following:

[0006] The product comprises the following raw material components by weight percentage: 5%-7% compound amino acids, 8%-10% sodium cocoyl apple amino acids, 4%-6% sea buckthorn fruit oil compound microcapsules, 4%-6% sorbitol, 0.2%-0.4% sodium hyaluronate, 0.7%-0.9% polyglycerol-4 laurate, 0.6%-0.8% preservatives, 0.08%-0.12% carbomer, 0.08%-0.12% triethanolamine, and the balance being deionized water; the sea buckthorn fruit oil compound microcapsules are bilayer microcapsules obtained by a stepwise encapsulation method, the bilayer microcapsules comprising an outer core material, an inner core material, and a wall material; the outer core material contains ceramide NP and phytosterols, the inner core material contains sea buckthorn fruit oil and vitamin E, and the wall material is β-cyclodextrin.

[0007] In this application, β-cyclodextrin utilizes a hydrophobic cavity to stably encapsulate sea buckthorn fruit oil and vitamin E through van der Waals forces and hydrogen bonds. Ceramide NP and phytosterols undergo interfacial self-assembly on the surface of the encapsulated core via ethanol-mediated interaction, forming a lipid complex coating layer adsorbed on the surface of β-cyclodextrin. During use, the hydrophobic interactions between molecules in the lipid complex layer are disrupted by weak mechanical friction during bathing, prompting the preferential release of the outer lipid layer. The combined effect of body surface temperature and a neutral pH environment regulated by triethanolamine promotes the slow dissociation of the β-cyclodextrin encapsulation system, avoiding the problem of simultaneous release of the core material. The preferentially released ceramide NP and phytosterols embed into the disordered lipid bilayer of the stratum corneum caused by lipid loss during cleansing through intermolecular forces, replenishing intercellular lipids, repairing the damaged skin barrier structure, and achieving an immediate barrier repair effect. Subsequently, the sea buckthorn fruit oil and vitamin E in the encapsulated core are continuously released. Vitamin E, as the main antioxidant, captures lipid peroxidation free radicals in the stratum corneum of the skin through phenolic hydroxyl hydrogen transfer, terminating the lipid peroxidation chain reaction. The flavonoids and polyphenols in the sea buckthorn fruit oil simultaneously scavenge oxygen free radicals, reducing the oxidative consumption of vitamin E and helping to maintain its antioxidant efficacy. At the same time, the small molecules of serine, glycine, and alanine in the compound amino acids can quickly penetrate into the stratum corneum to replenish moisture, providing a moist environment for lipid embedding in the disordered lipid bilayer. The large molecule sodium hyaluronate forms a dynamic hydration layer with water molecules through the hydroxyl and carboxyl groups on the molecular chain, delaying water evaporation. Sodium cocoyl apple amino acid and polyglycerol-4 laurate form mild micelles by regulating the hydrophilic-lipophilic balance of the system. The steric hindrance effect of the micelles prevents microcapsule aggregation and ensures its stable dispersion in the aqueous system.

[0008] Preferably, the preservative is phenoxyethanol and ethylparaben; the mass ratio of phenoxyethanol to ethylparaben is (2-3):1.

[0009] Preferably, the mass ratio of the outer core material, the inner core material, and the wall material is (1-2):(3-4):(4-6); the mass ratio of the ceramide NP and the phytosterol is (1.5-2.5):1; and the mass ratio of the sea buckthorn fruit oil and the vitamin E is (8-12):1.

[0010] Preferably, the compound amino acid is composed of serine, glycine and alanine; the mass ratio of serine, glycine and alanine is (0.8-1.2):(1.5-2.5):(0.8-1.2).

[0011] In this application, serine, glycine, and alanine are all small-molecule aliphatic amino acids with small molecular weight and suitable hydrophilicity. They can quickly penetrate the disordered lipid gaps in the stratum corneum after cleansing, making them suitable for short-staying shower gel use and avoiding the penetration obstruction of large-molecule amino acids. Glycine, in particular, has the least steric hindrance among naturally occurring amino acids, resulting in the fastest penetration rate and preferentially replenishing moisture lost after skin cleansing. The serine side chain contains hydroxyl functional groups, which form stable bonds with water molecules and stratum corneum lipids through hydrogen bonds, enhancing the water-locking effect and assisting in the reconstruction of the lipid bilayer. The slightly hydrophobic side chain of alanine can regulate the hydrophilic-hydrophobic balance of the system, avoiding localized water accumulation or stickiness caused by a single hydrophilic amino acid, while also improving the compatibility of the compound amino acids with stratum corneum lipids. This provides a moisturizing environment for ceramide NP and phytosterols to embed into the lipid bilayer, and all are naturally occurring amino acid components in the skin.

[0012] Secondly, this application provides a method for preparing a nourishing and repairing shower gel, comprising the following steps:

[0013] Step 1. Weigh sea buckthorn fruit oil and vitamin E, stir and mix until homogeneous to obtain an inner core material mixture; separately, add β-cyclodextrin to deionized water and stir to prepare a β-cyclodextrin aqueous solution; slowly add the inner core material mixture dropwise into the β-cyclodextrin aqueous solution, stir and encapsulate to obtain an inner microcapsule suspension; then weigh ceramide NP and phytosterol, add anhydrous ethanol and sonicate to dissolve to prepare an outer core material solution; add the outer core material solution to the inner microcapsule suspension, stir and spray dry to collect the dried powder, thus obtaining sea buckthorn fruit oil compound microcapsules;

[0014] Step 2. Weigh the amount of deionized water according to the formula and add it to the emulsification pot. Heat and stir, then add carbomer, sorbitol and sodium hyaluronate in sequence. Stir until completely dissolved, then keep warm and stir until the system is uniform and free of particles to obtain the first mixture.

[0015] Step 3. Add sodium cocoyl malic acid and polyglycerol-4 laurate to the first mixture, continue stirring, and after emulsification and dispersion, obtain the second mixture;

[0016] Step 4. After cooling the emulsification pot, add triethanolamine to the second mixture, stir to adjust the pH of the system, and continue to cool after the viscosity stabilizes; add compound amino acids, sea buckthorn fruit oil compound microcapsules, phenoxyethanol and ethylparaben in sequence, and stir until completely dispersed;

[0017] Step 5. Turn off the stirring, let it stand to degas, and then filter it through a filter screen to obtain the nourishing and repairing shower gel.

[0018] Preferably, in step 1, the mass ratio of β-cyclodextrin to deionized water is 1:(3-5); the mass ratio of the inner microcapsule suspension to anhydrous ethanol is 1:(0.3-0.8); the ultrasonic power is 150-300W and the time is 10-20min; the stirring temperature for preparing the β-cyclodextrin aqueous solution is 50-55℃ and the stirring time is 10-15min; the stirring and embedding temperature is 50-55℃ and the time is 30-40min; the stirring temperature for adding the outer core material solution to the inner microcapsule suspension is 60-65℃ and the stirring time is 25-30min; and the spray drying temperature is 120-130℃ and the time is 30-40min.

[0019] In this application, 50-55℃ promotes the dissolution of β-cyclodextrin and the formation of stable hydrophobic cavities. At room temperature, the dissolution rate of β-cyclodextrin is slow; the moderate temperature environment of 50-55℃ accelerates molecular thermal motion, promoting dissolution and unfolding the molecular structure, exposing more hydrophobic cavities. A temperature of 60-65℃ enhances the molecular activity of ceramide NP and phytosterols, making them more readily adsorbed onto the surface of β-cyclodextrin through hydrophobic interactions and van der Waals forces, forming a lipid complex coating layer. Too low a temperature reduces lipid molecular activity, resulting in low self-assembly efficiency and a loose coating layer; too high a temperature may damage the inner layer inclusion structure, leading to core material leakage.

[0020] Preferably, in step 2, the temperature for heating and stirring is 75-80℃, the stirring time is 30-40 minutes, and the holding and stirring time is 15-20 minutes.

[0021] Preferably, in step 3, the stirring temperature is 75-80℃ and the stirring time is 20-25 min.

[0022] Preferably, in step 4, the emulsifying pot is cooled to 55-60°C; the stirring time is 10-15 min; the pH is 6.5-7.5; and the temperature at which the viscosity is stabilized and the temperature is further cooled is 40-45°C.

[0023] In this application, the pH environment can maintain the stability of the β-cyclodextrin embedding system, avoid hydrogen bond breakage and premature leakage of the core material due to excessive acidity / alkalinity, and lay the foundation for the slow dissociation of β-cyclodextrin during subsequent use; on the other hand, it can maintain the molecular stability of the compound amino acids.

[0024] Preferably, in step 5, the time for static degassing is 10-15 minutes; and the mesh size of the filter is 180-220 mesh.

[0025] Compared with the prior art, the beneficial effects of this application are as follows:

[0026] This application provides a nourishing and repairing shower gel and its preparation method. In this application, β-cyclodextrin utilizes a hydrophobic cavity to form a stable coating of sea buckthorn fruit oil and vitamin E through van der Waals forces and hydrogen bonds. Ceramide NP and phytosterols undergo interfacial self-assembly on the surface of the inclusion core via ethanol-mediated interaction, forming a lipid complex coating layer adsorbed on the surface of β-cyclodextrin.

[0027] During use, the gentle mechanical friction during bathing disrupts the hydrophobic interactions between molecules in the lipid complex layer, prompting the preferential release of outer lipids. The combined effect of body surface temperature and a neutral pH environment regulated by triethanolamine promotes the slow dissociation of the β-cyclodextrin inclusion system, avoiding the issue of simultaneous release of the core material. The preferentially released ceramide NP and phytosterols embed themselves into the disordered lipid bilayer of the stratum corneum caused by cleansing through intermolecular forces, replenishing intercellular lipids, repairing the damaged skin barrier structure, and achieving immediate barrier repair. Subsequently, the sea buckthorn fruit oil and vitamin E in the inclusion core are continuously released. Vitamin E, as the primary antioxidant, captures lipid peroxidation free radicals in the stratum corneum through phenolic hydroxyl hydrogen transfer, terminating the lipid peroxidation chain reaction. The flavonoids and polyphenols in sea buckthorn fruit oil simultaneously scavenge oxygen free radicals, reducing the oxidative consumption of vitamin E and helping to maintain its antioxidant efficacy. Meanwhile, the small-molecule serine, glycine, and alanine in the compound amino acids can quickly penetrate into the stratum corneum to replenish moisture, providing a humid environment for lipid embedding in the disordered lipid bilayer; the large-molecule sodium hyaluronate forms a dynamic hydration layer with water molecules through the hydroxyl and carboxyl groups on its molecular chain, delaying water evaporation. Sodium cocoyl apple amino acids and polyglycerol-4 laurate form mild micelles by regulating the hydrophilic-lipophilic balance of the system, and the steric hindrance effect of the micelles prevents microcapsule aggregation, ensuring its stable dispersion in the aqueous system. Attached Figure Description

[0028] Figure 1 This is a schematic diagram of the preparation process of a nourishing and repairing body wash. Detailed Implementation

[0029] To make the technical problems, solutions, and beneficial effects of this application clearer, the following detailed description is provided in conjunction with embodiments. However, this should not be construed as limiting the scope of this application to the following examples. All other embodiments obtained by those skilled in the art without creative effort, without departing from the above-described methodological spirit, are within the scope of protection of this application.

[0030] In this application, the terminology used is for the purpose of describing particular embodiments only and is not intended to limit the scope of this application.

[0031] The singular forms “for,” “or,” “a,” “any,” and “the” used in this application are intended to include the plural forms unless the context clearly indicates otherwise.

[0032] The following will describe in detail, with reference to different embodiments, a nourishing and repairing shower gel and its preparation method provided in this application.

[0033] Example 1

[0034] like Figure 1 As shown, this embodiment provides a nourishing and repairing body wash and its preparation method, including the following steps:

[0035] Step 1. Weigh sea buckthorn fruit oil and vitamin E at a mass ratio of 8:1, and stir until homogeneous to obtain an inner core material mixture; separately, add β-cyclodextrin to deionized water, where the mass ratio of β-cyclodextrin to deionized water is 1:3, and stir at 50°C for 10 minutes to prepare a β-cyclodextrin aqueous solution; slowly drip the inner core material mixture into the β-cyclodextrin aqueous solution, and stir and encapsulate at 50°C for 30 minutes to obtain an inner microcapsule suspension; then, according to a mass ratio of 1.5:1... Weigh out ceramide NP and phytosterol, add anhydrous ethanol and sonicate for 10 min at 150 W to prepare an outer core material solution, wherein the mass ratio of the inner microcapsule suspension to anhydrous ethanol is 1:0.3; add the outer core material solution to the inner microcapsule suspension, stir at 60 °C for 25 min, then spray dry at 120 °C for 30 min and collect the dried powder to obtain sea buckthorn fruit oil compound microcapsules, wherein the mass ratio of outer core material, inner core material and wall material is 1:3:4;

[0036] Step 2. Weigh the amount of deionized water according to the formula and add it to the emulsification pot. Heat the pot to 75°C and stir for 30 minutes. Add 0.08% carbomer, 4% sorbitol and 0.2% sodium hyaluronate in sequence. Stir until completely dissolved, and then keep warm and stir for 15 minutes until the system is uniform and free of particles to obtain the first mixture.

[0037] Step 3. Slowly add 8% sodium cocoyl malic acid and 0.7% polyglycerol-4 laurate to the first mixture, and continue stirring at 75°C for 20 minutes to fully emulsify and disperse the surfactant, thus obtaining the second mixture;

[0038] Step 4. Reduce the temperature of the emulsifying pot to 60℃, add 0.08% triethanolamine to the second mixture, stir for 10 minutes to adjust the pH of the system to 6.5, and continue to cool to 40℃ after the viscosity stabilizes; add 5% compound amino acids, 4% sea buckthorn fruit oil compound microcapsules and 0.6% preservatives in sequence, wherein the preservatives include phenoxyethanol and ethylparaben, wherein the mass ratio of phenoxyethanol and ethylparaben is 2:1 and stir until completely dispersed; wherein the compound amino acids are composed of serine, glycine and alanine; the mass ratio of serine, glycine and alanine is 0.8:1.5:0.8;

[0039] Step 5. Turn off the stirring, let it stand to deaerate for 10 minutes, and then filter it through a 180-mesh filter to obtain the nourishing and repairing shower gel.

[0040] Example 2

[0041] like Figure 1 As shown, this embodiment provides a nourishing and repairing shower gel and its preparation method, including the following steps:

[0042] Step 1. Weigh sea buckthorn fruit oil and vitamin E at a mass ratio of 10:1, and stir until homogeneous to obtain an inner core material mixture; separately, add β-cyclodextrin to deionized water, where the mass ratio of β-cyclodextrin to deionized water is 1:4, and stir at 52℃ for 13 min to prepare a β-cyclodextrin aqueous solution; slowly drip the inner core material mixture into the β-cyclodextrin aqueous solution, and stir and encapsulate at 52℃ for 35 min to obtain an inner microcapsule suspension; then weigh the following at a mass ratio of 2:1: The outer core material solution was prepared by ultrasonically dissolving amide NP and phytosterol with anhydrous ethanol at 200W for 15 minutes, with the mass ratio of the inner microcapsule suspension to anhydrous ethanol being 1:0.5. The outer core material solution was added to the inner microcapsule suspension, stirred at 62℃ for 27 minutes, and then spray-dried at 125℃ for 35 minutes to collect the dried powder, which yielded the sea buckthorn fruit oil compound microcapsules, with the mass ratio of the outer core material, inner core material, and wall material being 1.5:3.5:5.

[0043] Step 2. Weigh the amount of deionized water according to the formula and add it to the emulsification pot. Heat the pot to 77°C and stir for 35 minutes. Add 0.1% carbomer, 5% sorbitol and 0.3% sodium hyaluronate in sequence. Stir until completely dissolved, and then keep warm and stir for 17 minutes until the system is uniform and free of particles to obtain the first mixture.

[0044] Step 3. Slowly add 9% sodium cocoyl malic acid and 0.8% polyglycerol-4 laurate to the first mixture, and continue stirring at 77°C for 23 minutes to fully emulsify and disperse the surfactant, thus obtaining the second mixture;

[0045] Step 4. Reduce the temperature of the emulsifying pot to 55℃, add 0.10% triethanolamine to the second mixture, stir for 12 minutes to adjust the pH of the system to 7, and continue to cool to 43℃ after the viscosity stabilizes; add 6% compound amino acids, 5% sea buckthorn fruit oil compound microcapsules and 0.7% preservatives in sequence, wherein the preservatives include phenoxyethanol and ethylparaben, wherein the mass ratio of phenoxyethanol to ethylparaben is 2.5:1 and stir until completely dispersed; wherein the compound amino acids are composed of serine, glycine and alanine; the mass ratio of serine, glycine and alanine is 1:2:1;

[0046] Step 5. Turn off the stirring, let it stand to deaerate for 13 minutes, and then filter it through a 200-mesh filter to obtain the nourishing and repairing shower gel.

[0047] Example 3

[0048] like Figure 1 As shown, this embodiment provides a nourishing and repairing body wash and its preparation method, including the following steps:

[0049] Step 1. Weigh sea buckthorn fruit oil and vitamin E at a mass ratio of 12:1, and stir until homogeneous to obtain an inner core material mixture; separately, add β-cyclodextrin to deionized water, where the mass ratio of β-cyclodextrin to deionized water is 1:5, and stir at 55°C for 15 min to prepare a β-cyclodextrin aqueous solution; slowly drip the inner core material mixture into the β-cyclodextrin aqueous solution, and stir and encapsulate at 55°C for 35 min to obtain an inner microcapsule suspension; then weigh ceramide NP and phytosterol at a mass ratio of 2.5:1. Anhydrous ethanol was added to the microcapsule suspension and ultrasonically dissolved for 20 minutes at 300W to prepare an outer core material solution, wherein the mass ratio of the inner microcapsule suspension to anhydrous ethanol was 1:0.8. The outer core material solution was added to the inner microcapsule suspension at a mass ratio of 2:4:6, and stirred at 65℃ for 30 minutes. Then, the mixture was spray-dried at 130℃ for 40 minutes to collect the dried powder, which yielded the sea buckthorn fruit oil compound microcapsules, wherein the mass ratio of the outer core material to the inner core material to the wall material was 2:4:6.

[0050] Step 2. Weigh the amount of deionized water according to the formula and add it to the emulsification pot. Heat the pot to 80°C and stir for 40 minutes. Add 0.12% carbomer, 6% sorbitol and 0.4% sodium hyaluronate in sequence. Stir until completely dissolved, and then keep warm and stir for 20 minutes until the system is uniform and free of particles to obtain the first mixture.

[0051] Step 3. Slowly add 10% sodium cocoyl malic acid and 0.9% polyglycerol-4 laurate to the first mixture, and continue stirring at 80°C for 25 minutes to fully emulsify and disperse the surfactant, thus obtaining the second mixture;

[0052] Step 4. Reduce the temperature of the emulsifying pot to 58℃, add 0.12% triethanolamine to the second mixture, stir for 15 minutes to adjust the pH of the system to 7.5, and continue to cool to 45℃ after the viscosity stabilizes; add 7% compound amino acids, 6% sea buckthorn fruit oil compound microcapsules and 0.8% preservatives in sequence, wherein the preservatives include phenoxyethanol and ethylparaben, wherein the mass ratio of phenoxyethanol and ethylparaben is 3:1 and stir until completely dispersed; wherein the compound amino acids are composed of serine, glycine and alanine; the mass ratio of serine, glycine and alanine is 1.2:2.5:1.2;

[0053] Step 5. Turn off the stirring, let it stand to deaerate for 15 minutes, and then filter it through a 220-mesh filter to obtain the nourishing and repairing body wash.

[0054] Comparative Example 1

[0055] Comparative Example 1 provides a nourishing and repairing shower gel and its preparation method, which differs from Example 3 in that it does not contain the sea buckthorn fruit oil compound microcapsules in steps 1 and 4.

[0056] Comparative Example 2

[0057] Comparative Example 2 provides a nourishing and repairing shower gel and its preparation method. The difference between Comparative Example 2 and Example 3 is that in step 1, only β-cyclodextrin is used to encapsulate sea buckthorn fruit oil and vitamin E, and no ceramide NP and phytosterols are added for outer coating.

[0058] Comparative Example 3

[0059] Comparative Example 3 provides a nourishing and repairing shower gel and its preparation method. The difference between Comparative Example 3 and Example 4 is that the compound amino acids are replaced with glycine in step 4, while the total amount added remains the same.

[0060] Comparative Example 4

[0061] Comparative Example 4 provides a nourishing and repairing shower gel and its preparation method. The difference between Comparative Example 4 and Example 3 is that in step 3, sodium lauryl ether sulfate is used instead of sodium cocoyl apple amino acid and polyglycerol-4 lauryl ester.

[0062] The performance of the nourishing and repairing body washes prepared in Examples 1-3 and Comparative Examples 1-4 was tested, and the specific methods are as follows:

[0063] 1. Long-term stability: After sealing the samples in their original packaging and storing them in an environment of 45℃ and 75% RH for 6 months, observe their appearance and measure their pH value, viscosity, and total number of microorganisms.

[0064] 2. Dispersion stability: Place the sample in a transparent centrifuge tube and let it stand for 30 days to observe whether there are any abnormal phenomena such as layering, precipitation, turbidity, or crystallization. Use a laser particle size analyzer to determine the average particle size of the microcapsules and the PDI (polydispersity index), and use a Malvern potentiometer to determine the zeta potential of the system.

[0065] 3. Physicochemical stability: The pH value of the sample was measured using a pH meter; the viscosity of the sample was measured using a rotational viscometer at 25℃ and 60r / min; the sample was centrifuged at 3000r / min for 30min and then observed for stratification or precipitation.

[0066] The performance test data analysis is as follows:

[0067] Table 1. Stability test data of the nourishing and repairing body washes prepared in Examples 1-3 and Comparative Examples 1-4 after 6 months of accelerated storage.

[0068]

[0069] As shown in Table 1, Examples 1-3 exhibited a significant increasing trend in various properties thanks to the gradient-optimized bilayer microcapsule system (β-cyclodextrin inner layer encapsulation, ceramide NP / phytosterol outer layer coating), the ternary compound amino acids (serine, glycine, and alanine), and the mild surfactants (sodium cocoyl malic acid and polyglycerol-4-laurate). Example 3 showed the best performance, maintaining a milky white and uniform liquid appearance, a stable pH of 7.4 (matching the physiological range of skin), a viscosity of 5310 mPa·s, and a total microbial count of <10 CFU / g, fully meeting the requirements for long-term storage. In this system, the bilayer microcapsules lock in the fat-soluble sea buckthorn fruit oil and vitamin E, preventing phase separation. The ceramide NP and phytosterol outer layer enhance the compatibility of the microcapsules with the formulation. The ternary compound amino acids play a synergistic buffering role to maintain pH stability, while the mild surfactant system ensures emulsification uniformity.

[0070] Compared with Example 3, Comparative Example 1 lacked the sea buckthorn fruit oil compound microcapsules. After losing the encapsulation protection, the fat-soluble components became incompatible with the aqueous system, resulting in obvious oil-water separation. The physical barrier effect of the microcapsules disappeared, leading to a large proliferation of microorganisms. The total number of microorganisms increased 20 times compared with Example 3. At the same time, there was no thickening contribution from the microcapsules to the system, and the viscosity dropped to 4200 mPa·s, which was 20.9% lower than that of Example 3, only 79.1% of it.

[0071] Comparative Example 2 used only a single-layer β-cyclodextrin microcapsule (without an outer ceramide NP / phytosterol coating). The imbalance of hydrophilicity and hydrophobicity on the surface of the microcapsule made it prone to aggregation, resulting in a slightly grainy appearance. Moreover, the protection of the single-layer encapsulation was insufficient, and the total number of microorganisms increased to 25 CFU / g, which was 150% higher than that of Example 3. Although the viscosity of 5100 mPa·s was close to that of Example 3, the stability was significantly weakened, and a complete synergistic stable network could not be formed.

[0072] Comparative Example 3 replaced the ternary compound amino acid with glycine. The single amino acid lacked synergistic buffering capacity, causing the pH to shift to 7.8 (alkaline), which was 5.4% higher than that of Example 3. Furthermore, the synergistic thickening effect of the multiple amino acids, surfactants, and microcapsules disappeared, and the viscosity dropped to 4950 mPa·s. Although there were no obvious abnormalities in appearance, the stability and compatibility of the system were not as good as those of the examples.

[0073] Comparative Example 4 used conventional sodium lauryl ether sulfate to replace the mild surfactant system. The hydrophilic-lipophilic balance value of sodium lauryl ether sulfate did not match the lipophilicity of the microcapsules, which damaged the emulsion stability and caused the liquid to become significantly thinner, with a viscosity of only 1900 mPa·s, which was 64.2% lower than that of Example 3, and only 35.8% of that. In addition, sodium lauryl ether sulfate is prone to hydrolysis during long-term storage, causing the pH to rise to 8.0.

[0074] Table 2. Dispersion stability data of the nourishing and repairing body washes prepared in Examples 1-3 and Comparative Examples 1-4.

[0075]

[0076] Table 2 shows that after 30 days of standing, Examples 1-3 showed no abnormalities such as stratification or precipitation. The average particle size of the microcapsules remained stable at 250-270 nm, with a uniform nanoscale distribution and a PDI ≤ 0.18, indicating a highly uniform particle size distribution. The absolute value of the Zeta potential was ≥ 34 mV, indicating strong electrostatic repulsion and effective inhibition of aggregation. Among them, Example 3, with its optimal microcapsule component ratio and process parameters, achieved a Zeta potential of -36 mV and a stable PDI of 0.16, demonstrating the best dispersion stability. The core mechanism lies in the precise matching of the hydrophilic and lipophilic balance between the outer lipid layer of the bilayer microcapsules and the surfactant system, reducing the interfacial tension between the microcapsules and the aqueous phase. Combined with the dispersing and regulating effect of the ternary compound amino acids, a dual stabilization mechanism of "steric hindrance effect and electrostatic repulsion" is formed, ensuring the uniform dispersion of microcapsules in the system.

[0077] Compared with Example 3, Comparative Example 1 lacked the sea buckthorn fruit oil compound microcapsules, and the fat-soluble components (sea buckthorn fruit oil and vitamin E) were not encapsulated and protected. Due to the severe imbalance of hydrophilicity and hydrophobicity with the aqueous system, severe stratification and oil ring phenomenon occurred after standing. The relevant particle size, PDI and Zeta potential indicators of the microcapsules were not applicable, highlighting the core role of microcapsules in solving the problem of fat-soluble component dispersion.

[0078] Comparative Example 2 used monolayer β-cyclodextrin microcapsules (without outer ceramide NP / phytosterol coating). The hydrophilicity and hydrophobicity of the microcapsule surface were unbalanced, and the lack of a compatibility bridge between the outer lipid and the formulation system led to weak aggregation of some microcapsules, which manifested as slight precipitation at the bottom of the bottle. Its PDI increased to 0.25 and the absolute value of the Zeta potential decreased to 28mV. Although the average particle size of the microcapsules was 280±30nm, the dispersion uniformity and stability were significantly weakened.

[0079] Comparative Example 3 replaced the ternary compound amino acid with glycine. Since the amino acid composition does not directly affect the particle size and surface charge characteristics of the microcapsules, its dispersion stability data is similar to that of Example 3, but the PDI is slightly higher than that of Example 3 and the absolute value of the Zeta potential is slightly lower. This indicates that the hydrophobic-hydrophilic functional groups of the ternary compound amino acid have a weak auxiliary regulation on the dispersion uniformity, and the single amino acid cannot completely replace this synergistic effect.

[0080] Comparative Example 4 used traditional sodium lauryl ether sulfate to replace the mild surfactant system. The hydrophilic-lipophilic balance value of sodium lauryl ether sulfate did not match the lipophilicity of the microcapsules, which disrupted the synergistic stability mechanism of "surfactant-microcapsule". This caused the PDI to rise to 0.22 and the absolute value of the Zeta potential to drop to 30mV. Although there was no obvious abnormality after standing, the dispersion uniformity and anti-agglomeration ability were weaker than those of the example. This proves that the precise control of the hydrophilic-lipophilic balance value of the mild surfactant system is an important prerequisite for ensuring the dispersion stability of microcapsules.

[0081] Table 3. Physicochemical stability data of the nourishing and repairing body washes prepared in Examples 1-3 and Comparative Examples 1-4

[0082]

[0083] Table 3 shows that after centrifugation, none of Examples 1-3 exhibited abnormal phenomena such as stratification or precipitation. The initial pH value remained stable within the skin physiological adaptation range of 6.5-7.5, and the initial viscosity gradually increased to 5500 mPa·s, with Example 3 showing the best performance. The core mechanism lies in the fact that the bilayer microcapsules form a precisely adapted emulsion network through the outer lipid and mild surfactant system, achieving high compatibility between the lipid-soluble core material and the aqueous system. The gel network formed by the crosslinking of carbomer and triethanolamine, combined with the synergistic effect of the hydrophilic-hydrophobic functional groups of the ternary compound amino acids, not only enhances the thickening effect of the system but also maintains pH stability through the buffering properties of amino acids. Under centrifugation conditions, the system structure remains homogeneous, avoiding phase separation or precipitation.

[0084] Compared with Example 3, Comparative Example 1 lacked the sea buckthorn fruit oil compound microcapsules. The unencapsulated fat-soluble components (sea buckthorn fruit oil, vitamin E) had a severe imbalance in hydrophilicity and hydrophobicity with the aqueous system. Lacking the physical separation and compatibility bridge of the microcapsules, severe oil-water separation occurred after centrifugation. Although the initial viscosity of 5300 mPa·s was close to that of Example 3, the inherent incompatibility between the fat and aqueous phases led to a complete failure of physicochemical stability, highlighting the core role of microcapsules in solving the compatibility problem between fat-soluble components and aqueous systems.

[0085] Comparative Example 2 used monolayer β-cyclodextrin microcapsules (without outer ceramide NP / phytosterol coating). The hydrophilicity and hydrophobicity of the microcapsule surface were not adequately regulated, and the interfacial compatibility with the formulation system was weaker than that of the bilayer structure. Under centrifugal force, some microcapsules agglomerated and precipitated, showing slight precipitation. Although its initial pH value and viscosity were similar to those of Example 3, the system homogeneity was insufficient, confirming that "outer lipid coating" is the key to optimizing the compatibility between microcapsules and the formulation and improving centrifugal stability.

[0086] Comparative Example 3 replaced the ternary compound amino acid with glycine. Since the single amino acid did not disrupt the emulsification network and gel structure of the system, its state after centrifugation and initial pH value were consistent with those of Example 3. The initial viscosity of 5350 mPa·s was only slightly lower than that of Example 3, indicating that the type of amino acid has little effect on the basic physicochemical stability. However, the "functional group synergistic buffering and slight thickening assistance" effect of the ternary compound amino acid disappeared, resulting in a viscosity slightly lower than that of Example 3, further demonstrating the synergistic optimization value of compound amino acids.

[0087] Comparative Example 4 used traditional sodium lauryl ether sulfate (SLES) instead of the mild surfactant system. SLES had poor compatibility with carbomer, failing to form a stable gel thickening network. Furthermore, its emulsifying properties were not well-suited to the microcapsules, resulting in a sharp drop in initial viscosity to 3000 mPa·s, a significant decrease compared to Example 3. Although no stratification or precipitation occurred after centrifugation, due to the strong emulsifying ability of SLES, the viscosity was still substandard. This demonstrates that the synergistic thickening effect of the mild surfactant system and carbomer is a crucial prerequisite for ensuring that the product's physicochemical properties meet usage requirements.

[0088] In summary, Examples 1-3 achieved excellent dispersion stability, physicochemical stability, and long-term storage stability of the nourishing and repairing shower gel through the synergistic effect of "double-layer microcapsule structure + ternary compound amino acid + mild surfactant system". Moreover, the pH value, viscosity and other indicators are precisely adapted to the physiological needs of the skin, and the overall performance is significantly better than that of the comparative examples.

[0089] The above results demonstrate and describe the basic principles and main features of this application, as well as its advantages.

[0090] Those skilled in the art should understand that this application is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this application. Various changes and modifications can be made to this application without departing from the spirit and scope thereof, and all such changes and modifications fall within the scope of this application as claimed. The scope of protection of this application is defined by the equivalents of the appended claims.

Claims

1. A nourishing and repairing body wash, characterized in that, The product comprises the following raw material components by weight percentage: 5%-7% compound amino acids, 8%-10% sodium cocoyl apple amino acids, 4%-6% sea buckthorn fruit oil compound microcapsules, 4%-6% sorbitol, 0.2%-0.4% sodium hyaluronate, 0.7%-0.9% polyglycerol-4 laurate, 0.6%-0.8% preservatives, 0.08%-0.12% carbomer, 0.08%-0.12% triethanolamine, and the balance being deionized water; the sea buckthorn fruit oil compound microcapsules are bilayer microcapsules obtained by a stepwise encapsulation method, the bilayer microcapsules comprising an outer core material, an inner core material, and a wall material; the outer core material contains ceramide NP and phytosterols, the inner core material contains sea buckthorn fruit oil and vitamin E, and the wall material is β-cyclodextrin.

2. The nourishing and repairing shower gel according to claim 1, characterized in that, The preservative is phenoxyethanol and ethylparaben; the mass ratio of phenoxyethanol to ethylparaben is (2-3):

1.

3. The nourishing and repairing shower gel according to claim 1, characterized in that, The mass ratio of the outer core material, inner core material, and wall material is (1-2):(3-4):(4-6); the mass ratio of the ceramide NP and the phytosterol is (1.5-2.5):1; and the mass ratio of the sea buckthorn fruit oil and the vitamin E is (8-12):

1.

4. The nourishing and repairing shower gel according to claim 1, characterized in that, The compound amino acid is composed of serine, glycine and alanine; the mass ratio of serine, glycine and alanine is (0.8-1.2):(1.5-2.5):(0.8-1.2).

5. A method for preparing a nourishing and repairing shower gel according to any one of claims 1-4, characterized in that, Includes the following steps: Step 1. Weigh sea buckthorn fruit oil and vitamin E, stir and mix until homogeneous to obtain an inner core material mixture; separately, add β-cyclodextrin to deionized water and stir to prepare a β-cyclodextrin aqueous solution; add the inner core material mixture dropwise to the β-cyclodextrin aqueous solution, stir and encapsulate to obtain an inner microcapsule suspension; then weigh ceramide NP and phytosterol, add anhydrous ethanol and sonicate to dissolve to prepare an outer core material solution; add the outer core material solution to the inner microcapsule suspension, stir and spray dry to collect the dried powder, thus obtaining sea buckthorn fruit oil compound microcapsules; Step 2. Weigh the amount of deionized water according to the formula and add it to the emulsification pot. Heat and stir, then add carbomer, sorbitol and sodium hyaluronate in sequence. Stir until completely dissolved, then keep warm and stir until the system is uniform and free of particles to obtain the first mixture. Step 3. Add sodium cocoyl malic acid and polyglycerol-4 laurate to the first mixture, continue stirring, and after emulsification and dispersion, obtain the second mixture; Step 4. After cooling the emulsification pot, add triethanolamine to the second mixture, stir to adjust the pH of the system, and continue to cool after the viscosity stabilizes; add compound amino acids, sea buckthorn fruit oil compound microcapsules, phenoxyethanol and ethylparaben in sequence, and stir until completely dispersed; Step 5. Turn off the stirring, let it stand to degas, and then filter it through a filter screen to obtain the nourishing and repairing shower gel.

6. The method for preparing a nourishing and repairing shower gel according to claim 5, characterized in that, In step 1, the mass ratio of β-cyclodextrin to deionized water is 1:(3-5); the mass ratio of the inner microcapsule suspension to anhydrous ethanol is 1:(0.3-0.8); the ultrasonic power is 150-300W and the time is 10-20min; the stirring temperature for preparing the β-cyclodextrin aqueous solution is 50-55℃ and the stirring time is 10-15min; the stirring and embedding temperature is 50-55℃ and the time is 30-40min; the stirring temperature for adding the outer core material solution to the inner microcapsule suspension is 60-65℃ and the stirring time is 25-30min; the spray drying temperature is 120-130℃ and the time is 30-40min.

7. The method for preparing a nourishing and repairing shower gel according to claim 5, characterized in that, In step 2, the temperature for heating and stirring is 75-80℃, the stirring time is 30-40 minutes, and the holding and stirring time is 15-20 minutes.

8. The method for preparing a nourishing and repairing shower gel according to claim 5, characterized in that, In step 3, the stirring temperature is 75-80℃ and the stirring time is 20-25 minutes.

9. The method for preparing a nourishing and repairing shower gel according to claim 5, characterized in that, In step 4, the emulsifying pot is cooled to 55-60℃; the stirring time is 10-15 minutes; the pH is 6.5-7.5; and the temperature at which the viscosity is stabilized and the temperature is further cooled is 40-45℃.

10. The method for preparing a nourishing and repairing shower gel according to claim 5, characterized in that, In step 5, the settling and degassing time is 10-15 minutes; the filter mesh size is 180-220 mesh.

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