基于特征解耦与物理残差校准的仪器分析迁移方法和系统

By using feature decoupling and physical residual calibration of a dual-stream deep neural network model, the problems of low migration accuracy and lack of physical basis for calibration in instrument analysis migration are solved, achieving cross-device migration with low sample cost and high robustness.

CN122065017BActive Publication Date: 2026-07-17SHANGHAI DEV CENT OF COMP SOFTWARE TECH

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHANGHAI DEV CENT OF COMP SOFTWARE TECH
Filing Date
2026-04-21
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing instrumental analysis transfer methods rely on a large number of labeled samples and fail to effectively consider the differences in instrument physical characteristics, resulting in low accuracy and insufficient robustness of transfer models, making it difficult to meet actual analytical needs.

Method used

A dual-stream deep neural network model is adopted, which extracts general chemical features through a shared feature branch and extracts response deviation features through a private deviation branch. By combining feature decoupling and physical residual calibration, the decoupling and calibration of instrument signals are realized, reducing computing power requirements and improving migration accuracy.

Benefits of technology

While reducing reliance on labeled samples, it improves the accuracy and robustness of cross-instrument analysis, achieves efficient transfer at low sample cost, and solves the problems of low transfer accuracy and lack of physical basis for calibration in existing technologies.

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Abstract

本申请公开了一种基于特征解耦与物理残差校准的仪器分析迁移方法和系统,涉及人工智能与仪器分析数据处理技术领域,该方法包括构建双流深度神经网络模型并特征解耦预训练,通过增加正交性惩罚项计算特征相关性损失并进行反向传播;获取待分析的仪器原始信号并输入至训练好的双流深度神经网络模型,以分别提取对应的通用化学特征与响应偏差特征,并基于通用化学特征通过加权聚合获取物理信号强度表征,同时基于线性响应原理,结合通用化学特征与响应偏差特征构建动态响应因子,计算得到定量分析结果。本申请可以在减少有标样本依赖的同时,提升跨仪器分析的准确性,实现低样本成本、高鲁棒性的仪器分析模型跨设备迁移。
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