Breast cancer neoadjuvant therapy prognosis multi-mode multi-task probability prediction method and system

By integrating various data from breast cancer patients using a multimodal, multi-task probabilistic prediction method, the potential outcomes of neoadjuvant therapy can be predicted. This addresses the issue of incomplete multimodal data integration in existing systems, improves the accuracy and interpretability of prognostic assessment, and provides objective support for individualized treatment plans.

CN122117368APending Publication Date: 2026-05-29MACAO POLYTECHNIC INST
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Patent Information

Application Number
CN202610134701.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-01-30
Publication Date
2026-05-29

AI Technical Summary

Technical Problem

Existing prognostic systems for neoadjuvant therapy in breast cancer fail to effectively integrate multimodal data, ignore imaging and histopathological heterogeneity, lack model interpretability, and lack counterfactual predictive capabilities, making it difficult to select individualized treatment options.

Method used

A multimodal, multi-task probabilistic prediction method was adopted to integrate breast DCE-MRI images, radiological imaging reports, pathological reports, and clinical information. Feature extraction and fusion were performed using a deep learning model to predict the potential outcomes of different neoadjuvant therapy regimens, explicitly describe prediction uncertainty, and reduce selection bias.

Benefits of technology

It improves the accuracy and interpretability of prognostic assessment for neoadjuvant therapy, provides objective support for treatment decision-making, reduces selection bias, and enables the recommendation of individualized treatment plans.

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Abstract

The invention discloses a breast cancer neoadjuvant therapy prognosis multi-mode multi-task probability prediction method and system, and the method comprises the steps: employing breast DCE-MRI images of a plurality of breast cancer patients after various neoadjuvant therapy and segmented images thereof; performing breast cancer NAT prognosis multi-mode multi-task probability prediction training on the deep learning model according to training data composed of clinical information, a radiology image report, a pathological report and case information; deep learning is utilized to analyze a mammary gland DCE-MRI image of a patient to be detected, a paired segmented image of the mammary gland DCE-MRI image, clinical information, a radiology image report, a pathological report and case information, and pCR, DFS and OS prediction results of various different NAT schemes and risk probability and recurrence probability evaluation results of breast cancer metastasis to different organs are generated and output. And identification results of benign and malignant tumor types and BI-RADS levels are obtained. According to the method, the accuracy and comprehensiveness of NAT prognosis evaluation can be remarkably improved.
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