A mouse tail skinner and its operating method

Abstract

The application provides a laboratory mouse tail skinner and an operating method thereof, which comprises a base, a cutting mechanism comprising a first assembly ring and a plurality of cutting assemblies, any cutting assembly comprising a first mounting seat and a cutting knife, the cutting knife being arranged on the first mounting seat and extending towards the center of the first assembly ring, and a skinning mechanism comprising a second assembly ring and a plurality of skinning assemblies, the second assembly ring being arranged concentrically with the first assembly ring, and the skinning assembly comprising a second mounting seat and a skinning knife, the skinning knife being connected to the second mounting seat and facing along the axial direction of the second assembly ring. The application replaces manual operation of a handheld blade with a mechanical structure, effectively avoiding the safety hazard of a sharp blade scratching the fingers of a laboratory worker. In addition, the application has a simple body structure and is convenient to assemble, can flexibly adjust the positions of the cutting assemblies and the skinning assemblies according to laboratory mouse tails of different specifications, has a wide range of applications, and has high practicality and promotional value.

Description

Technical Field

[0001] This invention relates to the field of biomedical experimental equipment technology, and in particular to a rat tail peeler and its operation method. Background Technology

[0002] In the field of biomedical research, laboratory mice are commonly used model organisms. Their tail tissues (including intervertebral discs, cartilage, nerves, and skin tissues) are an important source of samples for conducting experiments related to disease mechanism research, drug safety evaluation, and tissue engineering development. In particular, caudal intervertebral disc samples play an irreplaceable role in studies of spinal degeneration and cartilage repair. To obtain the above-mentioned target tissue samples, the first step is to longitudinally incise the mouse tail and peel off the skin to fully expose the caudal vertebrae and deep tissues, providing the basic conditions for subsequent sampling operations.

[0003] Currently, the standard procedure for incising and peeling the skin of a rat's tail still relies on manual operation by laboratory personnel. The specific procedure involves: after properly securing and disinfecting the rat, the operator makes multiple longitudinal incisions on the surface of the tail skin using a scalpel. Once a longitudinal incision is formed, the skin is manually torn open using tools such as forceps, ultimately separating the skin from the tailbone to expose deeper tissue samples. While this manual method is the most widely used and has a low barrier to entry, it suffers from several significant drawbacks in practical application, severely impacting experimental efficiency, sample quality, and operational safety. These drawbacks are as follows:

[0004] First, sample quality is difficult to guarantee, easily leading to contamination and damage. Because the rat tail has a conical structure and a smooth surface with no obvious points of leverage, manual cutting with a blade is prone to slippage, resulting in uneven cuts and varying depths. These irregular cuts not only significantly increase the difficulty of subsequent manual skin removal but also increase the risk of damaging deep tissues such as blood vessels and nerves around the tailbone during cutting or skin removal, causing tissue damage and bleeding. This can contaminate the target sample (such as the intervertebral disc) with blood or damaged tissue, affecting the accuracy of subsequent pathological analysis and molecular testing results, violating the quality control requirements for laboratory animal tissue sampling. Furthermore, for mice older than 21 days, their tailbone is gradually ossified, and their nerves and blood vessels are more fully developed, increasing the risk of deep tissue damage from manual cutting and potentially increasing the mouse's suffering, which does not conform to the 3R principle (reduce, replace, optimize) of laboratory animal ethics.

[0005] Secondly, the operation is unsafe and poses significant safety hazards. The scalpel blades used in the experiment are sharp, while the rat tails are small and prone to shaking during operation due to the rats struggling or being manually unstable. When the experimenter holds the sharp blade and makes multiple cuts on the small and unstable rat tail, there is a high risk of cutting their own fingers due to operational errors, resulting in occupational exposure risks. This safety hazard is even more prominent when handling a large number of experimental rats or when the operator is fatigued, which contradicts the safety requirements of experimental operations.

[0006] Finally, the operation is inefficient and hinders standardized experimental procedures. Manual cutting and peeling rely entirely on the operator's skill level. Differences in technique, cutting force, and speed among operators result in inconsistent incision quality and peeling effects, making it difficult to establish a standardized operating procedure. This affects the reproducibility and comparability of experiments, failing to meet the needs of high-throughput experiments and standardized research. Furthermore, manual procedures are cumbersome and time-consuming, especially when acquiring batches of rat tail tissue samples, where the inefficiency is even more pronounced, failing to meet the practical needs of efficient, large-scale sampling in biomedical research.

[0007] In summary, the current conventional manual methods for cutting and peeling the skin of laboratory mice's tails have many drawbacks, such as poor sample quality, significant safety risks, low operational efficiency, and difficulty in standardization. These methods cannot meet the needs of biomedical research for obtaining high-quality, efficient, safe, and standardized mouse tail tissue samples. Therefore, developing a device or method that can solve the above-mentioned technical defects has become an urgent technical problem to be solved in this field. Summary of the Invention

[0008] Therefore, the technical problem to be solved by the present invention is to overcome the problems of poor sample quality, great safety hazards, low operation efficiency and difficulty in standardization of the cutting of experimental mouse tail skin in the prior art, and to provide an experimental mouse tail peeler and its operation method.

[0009] To solve the above-mentioned technical problems, the present invention provides a laboratory rat tail peeler, which includes: a base;

[0010] A cutting mechanism, comprising a first assembly ring and multiple cutting components, wherein the first assembly ring is connected to the base, and each cutting component comprises a first mounting seat and a cutting blade, the first mounting seat being connected to the inner wall of the first assembly ring, and the cutting blade being disposed on the first mounting seat and extending toward the center of the first assembly ring to form a cut extending in a first direction on the tail of the experimental mouse; and a peeling mechanism, comprising a second assembly ring and multiple peeling components, wherein the second assembly ring is connected to the base and is concentrically disposed with the first assembly ring, and each peeling component comprises a second mounting seat and a peeling blade, the second mounting seat being connected to the inner wall of the second assembly ring, and the peeling blade being connected to the second mounting seat and extending along the axial direction of the second assembly ring.

[0011] In one embodiment of the present invention, the cutting mechanism includes four cutting components, which are evenly spaced along the inner wall of the first assembly ring; the peeling mechanism includes four peeling components, which are evenly spaced along the inner wall of the second assembly ring, and the projections of the four cutting components and the four peeling components in a first direction are alternately spaced.

[0012] In one embodiment of the present invention, the cutting assembly includes a first mounting post, a first elastic member, and a limiting member. One end of the first mounting post is inserted into a first mounting hole in the inner wall of the first assembly ring, and the other end is connected to the limiting member. A first mounting seat is disposed on the limiting member, and the first elastic member is sleeved on the first mounting post. The peeling assembly includes a second mounting post and a second elastic member. One end of the second mounting post is inserted into a second mounting hole in the inner wall of the second assembly ring, and the other end is connected to the second mounting seat. The second elastic member is sleeved on the second mounting post.

[0013] In one embodiment of the present invention, the first mounting base includes a connecting platform and a first locking member. The connecting platform is connected to the limiting member and has an assembly groove on the side facing the center of the first assembly ring. The cutting blade is detachably mounted in the assembly groove through the first locking member.

[0014] In one embodiment of the present invention, the second mounting base is configured as a frame structure, which has a skin discharge channel extending in a first direction inside. The peeling knife is connected to the upper surface of the skin discharge channel by a second locking member, and the skin strip of the experimental mouse tail is discharged along the skin discharge channel.

[0015] In one embodiment of the present invention, the functional end of the cutting blade extends obliquely to one side of its thickness along its length direction to form a single-sided oblique cutting edge, and the angle between the single-sided oblique cutting edge and the first direction is 10~15°.

[0016] In one embodiment of the present invention, the functional end of the peeling knife is configured as an arc-shaped structure matching the outer periphery of the experimental rat's tail, and extends obliquely to the thickness side along its length direction to form a single-sided oblique cutting edge.

[0017] In one embodiment of the present invention, the base includes a base plate and a bracket. The base plate is supported on the experimental table surface, and the lower surface of the base plate is provided with an anti-slip component. The bracket extends in a vertical direction, with one end fixed to the base plate and the other end connected to the first assembly ring and the second assembly ring.

[0018] This invention also provides a method for operating a laboratory rat tail peeler, which is used to peel the skin off the tail of a laboratory rat using the aforementioned laboratory rat tail peeler. The method includes: Step S1, measuring the diameter of the tail of the laboratory rat to be tested, and adjusting the positions of the cutting component and the peeling component in the laboratory rat tail peeler accordingly, so that the cutting blade fits against the tail of the laboratory rat, and the peeling blade is positioned between the skin and internal tissue of the tail of the laboratory rat; Step S2, inserting the end of the tail of the laboratory rat into the laboratory rat tail peeler along a first direction; Step S3, moving the tail of the laboratory rat along the first direction, so that the tail of the laboratory rat passes sequentially through the cutting mechanism and the peeling mechanism, wherein the cutting mechanism cuts an incision in the epidermis of the tail of the laboratory rat, and then the peeling blade in the peeling mechanism is positioned between the skin and internal tissue of the tail of the laboratory rat, so as to peel off the cut epidermis of the tail of the laboratory rat during the pulling process.

[0019] In one embodiment of the present invention, in step S3, the peeling knife peels the cut epidermis of the experimental mouse tail into skin strips, and the skin strips move along the skin discharge channel in the second mounting base to separate and discharge them from the internal tissue of the experimental mouse tail.

[0020] The technical solution of the present invention has the following advantages compared with the prior art:

[0021] The experimental rat tail peeler and its operating method described in this invention achieve stable assembly of the cutting mechanism and the peeling mechanism through a base, realizing a seamless connection between cutting and peeling operations, greatly improving operational efficiency. It eliminates the need for manual multiple cutting and peeling operations by experimental personnel, reducing the skill requirements for operators and facilitating standardized experimental procedures. The cutting mechanism can form a regular incision extending along a first direction on the experimental rat tail, and multiple cutting blades can adapt to the conical shape of the tail, achieving simultaneous multi-point cutting. This effectively avoids the problem of uneven cuts and varying depths caused by blade slippage during manual cutting, reducing damage to deep tissues of the rat tail during cutting, lowering the risk of sample contamination, and ensuring the accuracy of subsequent experimental results. The peeling mechanism can simultaneously and precisely peel off the rat tail skin after the cutting mechanism completes the incision, eliminating the need for manual skin tearing, further improving peeling efficiency, and avoiding secondary damage to deep tissues during manual skin tearing, further ensuring sample quality.

[0022] The entire structure replaces manual operation with a blade by using a mechanical structure, effectively avoiding the safety hazard of sharp blades cutting the fingers of experimental personnel, reducing occupational exposure risks, and improving the safety of experimental operations. In addition, the structure of this application is simple and easy to assemble. The positions of the cutting and peeling components can be flexibly adjusted according to the different sizes of experimental mouse tails, adapting to experimental mouse tails of different ages and thicknesses. It has a wide range of applications and can meet the actual needs of obtaining mouse tail tissue samples in batches, efficiently, and with high quality in biomedical research. It has high practicality and promotional value. Attached Figure Description

[0023] To make the content of this invention easier to understand, the invention will be further described in detail below with reference to specific embodiments and accompanying drawings.

[0024] Figure 1 This is a three-dimensional structural schematic diagram of the experimental rat tail peeler in a preferred embodiment of the present invention;

[0025] Figure 2 yes Figure 1 A three-dimensional structural diagram of the cutting mechanism in the experimental rat tail peeler shown;

[0026] Figure 3 yes Figure 1 A three-dimensional structural diagram of the cutting component in the experimental rat tail peeler shown;

[0027] Figure 4 yes Figure 1 A three-dimensional structural diagram of the skinning mechanism in the experimental rat tail skinning device shown;

[0028] Figure 5 yes Figure 1 A three-dimensional structural diagram of the peeling component in the experimental rat tail peeler shown;

[0029] Figure 6 yes Figure 5 Side view of the peeling component shown;

[0030] Figure 7 yes Figure 1 The diagram shows the structure of the experimental rat tail peeler in use.

[0031] Explanation of reference numerals in the accompanying drawings: 100, base; 110, bottom plate; 120, bracket; 200, cutting mechanism; 210, first assembly ring; 220, cutting assembly; 221, first mounting post; 222, first elastic element; 223, first mounting seat; 2231, connecting platform; 2232, first locking element; 224, cutting blade; 225, limiting element; 300, peeling mechanism; 310, second assembly ring; 320, peeling assembly; 321, second mounting post; 322, second elastic element; 323, second mounting seat; 3231, skin discharge channel; 324, second locking element; 325, peeling blade; 400, experimental rat tail; 410, incision; 420, skin strip; X, first direction; Y, second direction; Z, third direction. Detailed Implementation

[0032] The present invention will be further described below with reference to the accompanying drawings and specific embodiments, so that those skilled in the art can better understand and implement the present invention. However, the embodiments described are not intended to limit the present invention.

[0033] Example 1: See Figures 1 to 7 As shown, this embodiment provides a laboratory rat tail peeler, which includes: a base 100; a cutting mechanism 200, the cutting mechanism 200 including a first assembly ring 210 and a plurality of cutting components 220, the first assembly ring 210 being connected to the base 100, the cutting components 220 including a first mounting base 223 and a cutting blade 224, the first mounting base 223 being connected to the inner wall of the first assembly ring 210, the cutting blade 224 being disposed on the first mounting base 223 and extending toward the center of the first assembly ring 210, so as to peel the tail of the laboratory rat 4 A cut 410 extending along the first direction X is formed on the base 100; a peeling mechanism 300 is provided, the peeling mechanism 300 includes a second assembly ring 310 and a plurality of peeling components 320, the second assembly ring 310 is connected to the base 100 and is concentrically arranged with the first assembly ring 210, the peeling component 320 includes a second mounting seat 323 and a peeling knife 325, the second mounting seat 323 is connected to the inner wall of the second assembly ring 310, and the peeling knife 325 is connected to the second mounting seat 323 and is oriented along the axial direction of the second assembly ring 310.

[0034] It should be noted that, for ease of description, in this embodiment, the arrangement direction of the cutting mechanism 200 and the peeling mechanism 300 is defined as the first direction X, the width direction of the experimental rat tail peeler is defined as the second direction Y, and the height direction of the experimental rat tail peeler is defined as the third direction Z. The first direction X, the second direction Y and the third direction Z are arranged perpendicular to each other in pairs, and the first direction X and the second direction Y are located in the same plane.

[0035] In this embodiment, the base 100 mainly serves as an overall support structure, used to support and fix the cutting mechanism 200 and the peeling mechanism 300, ensuring the stability of their relative positions and providing a stable and reliable installation foundation for the rat tail cutting and peeling operations. Further, the base 100 in this embodiment includes a base plate 110 and a bracket 120. The base plate 110 is supported on the experimental table surface, and the lower surface of the base plate 110 is provided with anti-slip components. The bracket 120 extends vertically, with one end fixed to the base plate 110 and the other end connected to the first assembly ring 210 and the second assembly ring 310. The base plate 110 is used to support the experimental table, providing a stable foundation for the entire device. The anti-slip parts on its lower surface increase the friction between the device and the experimental table, effectively preventing the device from slipping during operation and ensuring the stability of the cutting and peeling operations. The bracket 120 extends vertically, with one end fixedly connected to the base plate 110 for reliable support, and the other end used to connect and fix the first assembly ring 210 and the second assembly ring 310, so that the cutting mechanism 200 and the peeling mechanism 300 are kept at a suitable operating height. At the same time, it ensures that the two assembly rings are fixed in relative position and concentrically arranged, providing stable structural support for the continuous cutting and peeling of the rat tail. In different embodiments, the specific structure of the base 100 can be adaptively adjusted according to actual practical needs, and the present invention does not impose specific limitations on this.

[0036] In this embodiment, the first assembly ring 210 is used to provide a unified mounting carrier for multiple cutting components 220, so that each cutting component 220 is evenly arranged in the circumferential direction, and at the same time, it works with the base 100 to realize the overall positioning of the cutting mechanism 200; the first mounting base 223 is used to stably install the cutting blade 224 on the inner wall of the first assembly ring 210, realize the positioning and fixation of the cutting blade 224, and ensure that the cutting blade 224 maintains the preset posture; the cutting blade 224 extends toward the center of the first assembly ring 210, and can cut the skin of the rat tail 400 when the rat tail 400 passes through the ring, forming a regular cut 410 extending along the first direction X, avoiding the slippage and uneven depth of the cut 410 that occur when cutting manually.

[0037] Correspondingly, the second assembly ring 310 is concentrically arranged with the first assembly ring 210 to provide an installation base for multiple peeling components 320, ensuring that the rat tail can be cut and peeled sequentially along the same axis, achieving a continuous and smooth process; the second mounting base 323 is used to fix the peeling knife 325 to the inner wall of the second assembly ring 310, ensuring the stability of the position and posture of the peeling knife 325; the peeling knife 325 is oriented along the axial direction of the second assembly ring 310, and can peel off the skin after the incision 410 is formed in the rat tail, replacing the manual peeling operation, reducing the risk of tissue damage and improving the safety and standardization of operation.

[0038] In this embodiment, the cutting mechanism 200 includes four cutting components 220, which are evenly spaced along the inner wall of the first assembly ring 210; the peeling mechanism 300 includes four peeling components 320, which are evenly spaced along the inner wall of the second assembly ring 310, and the projections of the four cutting components 220 and the four peeling components 320 on the first direction X are alternately spaced. Four cutting components 220 are evenly spaced along the inner wall of the first assembly ring 210, enabling simultaneous cutting of the rat tail skin from multiple circumferential directions. This ensures that the cuts 410 are evenly distributed and under stable force, avoiding deviation and slippage caused by unilateral cutting. The peeling mechanism 300 is correspondingly provided with four peeling components 320, evenly spaced along the inner wall of the second assembly ring 310. These components can work in conjunction with the cuts 410 to perform peeling actions synchronously from the circumferential direction, making skin peeling smoother and more efficient. At the same time, the projections of the four cutting components 220 and the four peeling components 320 on the first direction X are alternately spaced, which can effectively avoid positional interference between the cutting and peeling components in the axial direction, ensuring that the cutting and peeling processes are carried out continuously and smoothly, and improving the reliability and stability of the overall structure.

[0039] Specifically, in this embodiment, the cutting assembly 220 includes a first mounting post 221, a first elastic member 222, and a limiting member 225. One end of the first mounting post 221 is inserted into a first mounting hole in the inner wall of the first assembly ring 210, and the other end is connected to the limiting member 225. The first mounting seat 223 is disposed on the limiting member 225, and the first elastic member 222 is sleeved on the first mounting post 221. The first mounting post 221 provides radial movement guidance and installation positioning for the cutting assembly 220. The other end is connected to the limiting member 225, which can limit the movement stroke of the first mounting post 221 and prevent it from detaching from the first assembly ring 210. The first elastic member 222 can provide radial elastic preload for the cutting assembly 220, so that the cutting blade 224 can adaptively adjust its radial position according to the thickness of the experimental rat tail 400, ensuring effective cutting while avoiding excessive compression and damage to the rat tail tissue. The limiting member 225 is used to install and fix the first mounting base 223, and at the same time, it works with the first elastic member 222 to achieve elastic reset and limiting of the cutting assembly 220, ensuring that the cutting blade 224 always maintains a stable working posture.

[0040] Furthermore, in this embodiment, the first mounting base 223 includes a connecting platform 2231 and a first locking member 2232. The connecting platform 2231 is connected to the limiting member 225, and has an assembly groove on the side facing the center of the first assembly ring 210. The cutting blade 224 is detachably installed in the assembly groove through the first locking member 2232. The connecting platform 2231 is connected to the limiting member 225, and the assembly groove is used to accommodate and position the cutting blade 224, providing a stable mounting base for the cutting blade 224. The first locking member 2232 detachably installs the cutting blade 224 in the assembly groove, which not only ensures that the cutting blade 224 is firmly positioned and does not loosen or shift during operation, ensuring stable and reliable cutting, but also facilitates quick disassembly and replacement when the cutting blade 224 is worn or damaged, improving the flexibility of use and ease of maintenance of the device.

[0041] Correspondingly, the peeling assembly 320 includes a second mounting post 321 and a second elastic element 322. One end of the second mounting post 321 is inserted into a second mounting hole in the inner wall of the second assembly ring 310, and the other end is connected to the second mounting seat 323. The second elastic element 322 is sleeved on the second mounting post 321. The second mounting post 321 provides radial mounting positioning and movement guidance for the peeling assembly 320, and the other end is connected to the second mounting seat 323 to achieve reliable installation of the peeling knife 325. The second elastic element 322 can provide radial elastic force to the peeling assembly 320, so that the peeling knife 325 can adaptively adjust its radial position according to the conical shape of the experimental rat tail 400. While closely adhering to the rat tail skin to ensure the peeling effect, it avoids rigid compression damage to the deep tissues of the rat tail, improving the adaptability and safety of the operation.

[0042] In this embodiment, the second mounting base 323 is configured as a frame structure, with a skin removal channel 3231 extending along the first direction X inside. The peeling knife 325 is connected to the upper surface of the skin removal channel 3231 via a second locking member 324, and the skin strip 420 of the experimental rat tail 400 is discharged along the skin removal channel 3231. The design of the skin removal channel 3231 provides a regular passage and discharge space for the peeled rat tail skin strip 420, avoiding the skin strip 420 from tangling and accumulating, which would affect subsequent operations. The peeling knife 325 is connected to the upper surface of the skin removal channel 3231 via the second locking member 324, ensuring that the peeling knife 325 is securely installed and has reliable cutting capabilities, while also facilitating the disassembly, replacement, and maintenance of the peeling knife 325. The skin strip 420 formed by cutting the experimental rat tail 400 can be smoothly discharged outward along the skin removal channel 3231, making the peeling process continuous and orderly, and further improving the smoothness and efficiency of the rat tail peeling operation.

[0043] In this embodiment, the functional end of the cutting blade 224 extends obliquely to one side of its thickness along its length to form a single-sided oblique cutting edge, and the angle between the single-sided oblique cutting edge and the first direction X is 12°. This structure enables the cutting edge to better fit the arc-shaped surface of the experimental mouse tail 400, achieving directional cutting during cutting and effectively reducing blade slippage. In different implementations, the angle between the single-sided oblique cutting edge and the first direction X can be configured to 10~15° according to actual usage requirements. This reduces the risk of damage to deep tissues of the mouse tail and improves cutting stability and sample integrity while ensuring that the cut 410 is straight, regular, and of uniform and appropriate depth.

[0044] Correspondingly, the functional end of the peeling blade 325 is configured as an arc-shaped structure matching the outer periphery of the experimental mouse tail 400, and extends obliquely towards its thickness along its length to form a single-sided oblique cutting edge. The arc-shaped structure design can closely fit the conical outer contour of the mouse tail, ensuring uniform force and reliable fit during peeling. At the same time, its functional end extends obliquely towards its thickness along its length to form a single-sided oblique cutting edge, which can achieve smooth cutting and separation when the mouse tail skin is peeled along the incision 410, avoiding tearing or damage to the subcutaneous tissue, and further improving the peeling effect and sample integrity.

[0045] Example 2: This example provides a method for operating a laboratory rat tail peeler, which is used to peel the skin off the tail of a laboratory rat 400 using the laboratory rat tail peeler described in Example 1, and includes:

[0046] Step S1: Measure the diameter of the mouse tail 400 and adjust the positions of the cutting component 220 and peeling component 320 in the mouse tail peeler accordingly, so that the cutting blade 224 is attached to the mouse tail 400 and the peeling blade 325 is positioned between the skin and internal tissue of the mouse tail 400. By first measuring the diameter of the mouse tail 400 to be processed, the thickness parameter of the mouse tail can be accurately obtained. Then, the positions of the cutting component 220 and peeling component 320 are adjusted accordingly, so that the cutting blade 224 is attached to the surface of the mouse tail 400, ensuring that the subsequent cutting can accurately act on the skin without damaging the deep tissue. At the same time, the peeling blade 325 is pre-embedded between the skin and internal tissue of the mouse tail 400, which prepares for the subsequent peeling action and avoids irregular cutting, unsmooth peeling, or tissue damage due to differences in the thickness of the mouse tail. This ensures the adaptability of the operation and the integrity of the sample, while reducing the difficulty of operation and improving the standardization of the operation.

[0047] Step S2: Insert the end of the experimental rat tail 400 into the experimental rat tail peeler along the first direction X. Inserting the end of the experimental rat tail 400 into the experimental rat tail peeler along the first direction X allows the rat tail to enter along the concentric axis of the device, ensuring that the rat tail can be accurately aligned with the working areas of the cutting mechanism 200 and the peeling mechanism 300. This ensures that when the rat tail is moved subsequently, it can pass smoothly through the cutting mechanism 200 and the peeling mechanism 300 in sequence, avoiding tail deviation that could lead to cutting misalignment or peeling failure. At the same time, it lays the foundation for the continuous operation in step S3, ensuring that the entire operation process is coherent and orderly.

[0048] Step S3: Move the experimental mouse tail 400 along the first direction X, so that the experimental mouse tail 400 passes through the cutting mechanism 200 and the peeling mechanism 300 in sequence. The cutting mechanism 200 cuts an incision 410 in the epidermis of the experimental mouse tail 400. Then, the peeling blade 325 in the peeling mechanism 300 is located between the skin and internal tissue of the experimental mouse tail 400, so as to peel off the cut epidermis of the experimental mouse tail 400 during the pulling process. The experimental mouse tail 400 is moved along the first direction X, causing it to pass through the cutting mechanism 200 and the peeling mechanism 300 in sequence, completing a continuous cutting and peeling operation. During the movement of the mouse tail, the cutting mechanism 200 precisely cuts the mouse tail epidermis, forming a regular incision 410, which facilitates subsequent skin peeling and solves the problem of uneven incisions 410 when manually cutting. Subsequently, the peeling blade 325 in the peeling mechanism 300 is positioned in advance between the mouse tail skin and the internal tissue. During the pulling of the mouse tail, it can accurately act on the gap between the skin and the deep tissue, smoothly peeling off the cut mouse tail epidermis, replacing the manual peeling operation. This not only improves peeling efficiency but also avoids damage to the deep tissue during the tearing process, ensuring sample quality. At the same time, it realizes the integrated and continuous operation of cutting and peeling, reducing the complexity of operation and improving the safety and standardization of operation.

[0049] Specifically, in this embodiment, the peeling blade 325 peels the cut skin of the mouse tail 400 into skin strips 420. The skin strips 420 move along the skin discharge channel 3231 in the second mounting base 323 to separate from the internal tissue of the mouse tail 400 and discharge them. This structural design allows for smooth separation from the internal tissue of the mouse tail 400 and completion of discharge while conveying the skin strips in an orderly manner, avoiding entanglement, jamming, or retraction of the skin strips 420, ensuring a continuous and stable peeling process, and preventing secondary interference or damage to the internal tissue.

[0050] In summary, the experimental rat tail peeler and its operating method described in this invention achieve stable assembly of the cutting mechanism 200 and the peeling mechanism 300 through the base 100, realizing seamless connection between cutting and peeling operations, greatly improving operating efficiency, eliminating the need for experimenters to manually perform multiple cutting and peeling operations, reducing the requirements for experimenters' operational proficiency, and facilitating standardized experimental operations; the cutting mechanism 200 can form a regular incision 410 extending along the first direction X on the experimental rat tail 400, and multiple cutting blades 224 can adapt to the conical shape of the rat tail, realizing multi-point synchronous cutting, effectively avoiding the problem of uneven incisions 410 caused by blade slippage during manual cutting, reducing damage to the deep tissues of the rat tail during cutting, reducing the risk of sample contamination, and ensuring the accuracy of subsequent experimental results; the peeling mechanism 300 can simultaneously and precisely peel off the rat tail skin after the cutting mechanism 200 completes the incision 410, eliminating the need to manually tear the skin, further improving peeling efficiency, and avoiding secondary damage to deep tissues during manual peeling, further ensuring sample quality.

[0051] The entire structure replaces manual operation with a blade by using a mechanical structure, effectively avoiding the safety hazard of sharp blades cutting the fingers of experimental personnel, reducing occupational exposure risks, and improving the safety of experimental operations. In addition, the overall structure of this application is simple and easy to assemble. The positions of the cutting component 220 and the peeling component 320 can be flexibly adjusted according to different specifications of experimental mouse tails 400, adapting to experimental mouse tails 400 of different ages and thicknesses. It has a wide range of applications and can meet the actual needs of obtaining mouse tail tissue samples in batches, efficiently, and with high quality in biomedical research. It has high practicality and promotion value.

[0052] Obviously, the above embodiments are merely illustrative examples for clear explanation and are not intended to limit the implementation. Those skilled in the art will recognize that other variations or modifications can be made based on the above description. It is neither necessary nor possible to exhaustively list all possible implementations here. However, obvious variations or modifications derived therefrom are still within the scope of protection of this invention.

Claims

1. A laboratory rat tail peeler, characterized in that: include: Base; A cutting mechanism, comprising a first assembly ring and a plurality of cutting components, wherein the first assembly ring is connected to the base, and the cutting components include a first mounting seat and a cutting blade, wherein the first mounting seat is connected to the inner wall of the first assembly ring, and the cutting blade is disposed on the first mounting seat and extends toward the center of the first assembly ring to form a cut extending in a first direction on the tail of a laboratory mouse. A peeling mechanism includes a second assembly ring and multiple peeling components. The second assembly ring is connected to the base and is concentrically arranged with the first assembly ring. Each peeling component includes a second mounting seat and a peeling knife. The second mounting seat is connected to the inner wall of the second assembly ring, and the peeling knife is connected to the second mounting seat and faces the second assembly ring along its axial direction.

2. The experimental rat tail peeler according to claim 1, characterized in that: The cutting mechanism includes four cutting components, which are evenly spaced along the inner wall of the first assembly ring; the peeling mechanism includes four peeling components, which are evenly spaced along the inner wall of the second assembly ring, and the projections of the four cutting components and the four peeling components in the first direction are alternately spaced.

3. The experimental rat tail peeler according to claim 1, characterized in that: The cutting assembly includes a first mounting post, a first elastic element, and a limiting element. One end of the first mounting post is inserted into a first mounting hole in the inner wall of the first assembly ring, and the other end is connected to the limiting element. The first mounting seat is disposed on the limiting element, and the first elastic element is sleeved on the first mounting post. The peeling assembly includes a second mounting post and a second elastic element. One end of the second mounting post is inserted into a second mounting hole in the inner wall of the second assembly ring, and the other end is connected to the second mounting seat. The second elastic element is sleeved on the second mounting post.

4. The experimental rat tail peeler according to claim 3, characterized in that: The first mounting base includes a connecting platform and a first locking member. The connecting platform is connected to the limiting member and has an assembly groove on the side facing the center of the first assembly ring. The cutting blade is detachably mounted in the assembly groove through the first locking member.

5. The experimental rat tail peeler according to claim 1, characterized in that: The second mounting base is configured as a frame structure, and its interior is provided with a skin discharge channel extending along the first direction. The peeling knife is connected to the upper surface of the skin discharge channel by a second locking member, and the skin strip of the experimental mouse tail is discharged along the skin discharge channel.

6. The experimental rat tail peeler according to claim 1, characterized in that: The functional end of the cutting blade extends obliquely along its length towards its thickness to form a single-sided oblique cutting edge, and the angle between the single-sided oblique cutting edge and the first direction is 10~15°.

7. The experimental rat tail peeler according to claim 1, characterized in that: The functional end of the peeling knife is configured as an arc-shaped structure that matches the outer periphery of the experimental rat's tail, and extends obliquely to the thickness side along its length to form a single-sided oblique cutting edge.

8. The experimental rat tail peeler according to claim 1, characterized in that: The base includes a base plate and a bracket. The base plate is supported on the experimental table surface, and the lower surface of the base plate is provided with anti-slip components. The bracket extends vertically, with one end fixed to the base plate and the other end connected to the first assembly ring and the second assembly ring.

9. A method for operating a laboratory rat tail peeler, characterized in that: Used for skin peeling of laboratory mouse tails using the laboratory mouse tail peeler according to any one of claims 1 to 8, comprising: Step S1: Measure the diameter of the tail of the mouse to be tested, and adjust the position of the cutting component and the peeling component in the mouse tail peeler accordingly, so that the cutting blade fits against the mouse tail and the peeling blade is located between the skin and internal tissue of the mouse tail. Step S2: Insert the end of the experimental mouse tail into the experimental mouse tail peeler along the first direction; Step S3: Move the mouse tail along the first direction so that the mouse tail passes through the cutting mechanism and the peeling mechanism in sequence. The cutting mechanism cuts an incision in the mouse tail skin, and then the peeling blade in the peeling mechanism is located between the skin and internal tissue of the mouse tail to peel off the cut mouse tail skin during the pulling process.

10. The method of operating the experimental rat tail peeler according to claim 9, characterized in that: In step S3, the peeling knife peels the cut lab rat tail epidermis into skin strips, which move along the skin strip discharge channel in the second mounting base to separate and discharge from the internal tissue of the lab rat tail.

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