Loading mechanism, biochemical substance analysis device, and biochemical substance analysis system

Abstract

A loading mechanism (200), a biochemical analysis device (100), and a biochemical analysis system (1000) are disclosed. The loading mechanism (200) includes a base (10), a mounting base (20), and a loading platform (30). The base (10) includes a support surface (11) defining a first direction (X) perpendicular to the support surface (11). The mounting base (20) is fixed to the support surface (11) and has a first guide groove (21), at least a portion of which is inclined relative to the first direction (X). The loading platform (30) is configured to hold a first component (1) and a second component (2) and is movably disposed on the support surface (11) along the first direction (X). The second component (2) has a first guide member (2b) slidably disposed in the first guide groove (21). The first guide groove (21) is configured to cooperate with the first guide (2b) such that when the loading platform (30) moves toward the support surface (11) in the first direction (X), the second component (2) moves toward the first component (1) in the second direction (Y) perpendicular to the first direction (X) and assembles with the first component (1).

Description

Loading mechanism, biochemical substance analysis device, and biochemical substance analysis system Technical Field

[0001] The present application relates to the field of analysis and testing, and in particular to a loading mechanism, a biochemical substance analysis device having the loading mechanism, and a biochemical substance analysis system having the biochemical substance analysis device. Background Art

[0002] A detection device is a component required for analytical instruments such as gene sequencers. It's the area where the sample reacts with the reagents, generating a corresponding signal. The analytical instrument receives and analyzes this signal. During use, the detection device is temporarily mounted on the analytical instrument, establishing a conductive path for electrical signals between the two instruments.

[0003] In the related art, the card holder of the analytical instrument needs to be manipulated to rotate to provide operating space for the subsequent insertion of the detection device. The detection device is then inserted into the card holder by manual insertion, and then the card holder is pressed to return to its original position. However, if the card holder is skewed during insertion, the metal contacts in the card holder are unevenly stressed and prone to wear, affecting the transmission of electrical signals. Moreover, if there are many metal contacts, the resistance encountered during insertion of the detection device increases, causing inconvenience to the user.

[0004] Summary of the Invention

[0005] In order to solve at least one of the above defects, it is necessary to provide a loading mechanism, a biochemical substance analysis device and a biochemical substance analysis system.

[0006] According to a first aspect of the present application, there is provided a loading mechanism configured to assemble a first component with a second component. The loading mechanism includes a base, a mounting seat, and a loading platform. The base includes a support surface, and a first direction is defined to be perpendicular to the support surface. The mounting seat is fixed to the support surface, and the mounting seat is provided with a first guide groove, at least part of which is inclined relative to the first direction. The loading platform is configured to place the first component and the second component, and is movably provided on the support surface along the first direction. The second component is provided with a first guide member that is slidably provided in the first guide groove. The first guide groove is configured to cooperate with the first guide member, so that when the loading platform moves along the first direction toward the support surface, the second component moves along a second direction perpendicular to the first direction toward the first component and is assembled with the first component.

[0007] A second aspect of the present application provides a biochemical substance analysis device, comprising a second component. The biochemical substance analysis device further comprises the loading mechanism described above, wherein the second component is disposed on a loading platform of the loading mechanism.

[0008] A third aspect of the present application provides a biochemical substance analysis system comprising a first component, the biochemical substance analysis system further comprising the biochemical substance analysis device as described above, the first component being configured to be placed on a loading platform of a loading mechanism of the biochemical substance analysis device and assembled with the second component.

[0009] In the present application, the user only needs to place the first component on the loading platform, and then manipulate the loading platform to move along the first direction toward the support surface. Since at least part of the first guide groove is tilted relative to the first direction, during the movement of the loading platform, the cooperation between the first guide groove and the first guide member causes the second component to move along the second direction toward the first component until the second component is assembled with the first component. That is, the present application avoids manually plugging the first component to the second component, thereby reducing the risk of wear or even skewness of the second component when the two are not aligned, and improving the stability of the conduction of electrical signals. Moreover, changing manual plugging to manipulating the loading platform to move along the first direction can improve the convenience of user operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0010] FIG1 is an exploded view of a biochemical substance analysis system provided in one embodiment of the present application.

[0011] FIG. 2 is a schematic structural diagram of a biochemical substance analysis device in the biochemical substance analysis system shown in FIG. 1 .

[0012] FIG3 is a schematic structural diagram of a first component and a second component in the biochemical substance analysis system shown in FIG1 .

[0013] FIG. 4 is an exploded view of the first component shown in FIG. 3 .

[0014] FIG5 is a cross-sectional view of the biochemical substance analyzing device shown in FIG2 along line VV.

[0015] FIG6 is a schematic structural diagram of the base, the mounting base, and the assembly table in the biochemical substance analysis device shown in FIG2 .

[0016] FIG. 7 is an exploded view of the assembly station shown in FIG. 6 .

[0017] FIG8 is a schematic structural diagram of the first mounting portion of the mounting base shown in FIG6 .

[0018] FIG9 is a schematic structural diagram of the second mounting portion of the mounting base shown in FIG6 .

[0019] FIG10 is a schematic structural diagram of another second mounting portion of the mounting base shown in FIG6 .

[0020] FIG. 11 is a schematic structural diagram of an operating element in the biochemical substance analysis device shown in FIG. 2 .

[0021] FIG. 12 is a schematic structural diagram of a locking member in the biochemical substance analysis device shown in FIG. 2 .

[0022] FIG13 is a schematic structural diagram of the biochemical substance analysis system shown in FIG1 in one state.

[0023] FIG14 is a schematic structural diagram of the biochemical substance analysis system shown in FIG1 in another state.

[0024] Description of main component symbols

[0025] First component 1

[0026] Microfluidic chip 1a

[0027] Detection chip 1b

[0028] Carrier board 1c

[0029] Second component 2

[0030] Plug port 2a

[0031] First guide 2b

[0032] Heat transfer element 3

[0033] First heat transfer portion 3a

[0034] Second heat transfer part 3b

[0035] Base 10

[0036] Support surface 11

[0037] Bottom 12

[0038] Guide shaft 13

[0039] First window 14

[0040] The third elastic member 15

[0041] Mounting Block 20

[0042] First mounting portion 20a

[0043] Second mounting portion 20b

[0044] First guide groove 21

[0045] Second guide groove 22

[0046] First sliding groove 23

[0047] Loading station 30

[0048] First positioning groove 31

[0049] Second positioning groove 32

[0050] The third positioning groove 33

[0051] Guide hole 34

[0052] Second window 35

[0053] Transmission unit 36

[0054] Limiting piece 40

[0055] Second guide 40a

[0056] Operating member 50

[0057] Rotating portion 51

[0058] Second sliding groove 51a

[0059] Operation unit 52

[0060] Recessed portion 52a

[0061] First elastic member 53

[0062] Locking piece 60

[0063] Base 61

[0064] Locking portion 62

[0065] Second elastic member 63

[0066] Biochemical substance analysis device 100

[0067] Loading mechanism 200

[0068] First paragraph 211

[0069] Section 212

[0070] Section 3 213

[0071] Section 4 221

[0072] Section 5, 222

[0073] Section 6 223

[0074] First Arm 531

[0075] Second arm 532

[0076] Ontology 621

[0077] Tongue 622

[0078] Third Arm 631

[0079] Fourth arm 632

[0080] Biochemical Material Analysis System 1000

[0081] First end portion 2111

[0082] Second end portion 2112

[0083] The third end portion 2211

[0084] Fourth end portion 2212

[0085] Locking surface 6220

[0086] Inclined surface 6221

[0087] First electrical connection portion C1

[0088] First electrical connection portion C2

[0089] First direction X

[0090] Second direction Y

[0091] The third direction Z

[0092] First rotating shaft S1

[0093] Second rotating shaft S2

[0094] The following specific implementation methods will further illustrate the present application in conjunction with the above-mentioned drawings. DETAILED DESCRIPTION

[0095] In order to more clearly understand the above-mentioned objects, features and advantages of the present application, the present application is described in detail below in conjunction with the accompanying drawings and specific embodiments. It should be noted that, in the absence of conflict, the embodiments of the present application and the features in the embodiments can be combined with each other. In the following description, many specific details are set forth to facilitate a full understanding of the present application. The embodiments described are only a part of the embodiments of the present application, rather than all of the embodiments.

[0096] In the description of the present application, it should be understood that the terms "upper", "lower", "front", "back", "top", "bottom", "inside", "outside" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present application. In addition, the terms "first" and "second" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the said features. In the description of the present application, it should be noted that the meaning of "multiple" is two or more, unless otherwise clearly and specifically defined.

[0097] In the description of this application, it should be noted that, unless otherwise expressly specified or limited, the terms "installed" and "connected" should be understood in a broad sense. For example, they can refer to fixed connections, detachable connections, or integral connections; they can refer to mechanical connections, electrical connections, or mutual communication; they can refer to direct connections or indirect connections through an intermediate medium; they can refer to internal communication between two components or the interaction between two components. Those skilled in the art will understand the specific meanings of the above terms in this application based on specific circumstances.

[0098] Figure 1 shows a biochemical substance analysis system 1000 provided in one embodiment of the present application, including a first component 1 and a biochemical substance analysis device 100. Figure 2 shows the biochemical substance analysis device 100 obtained by removing the first component 1 from the biochemical substance analysis system 1000 shown in Figure 1. Among them, the first component 1 can be used to accommodate fluids (such as biological samples and reagents) and detect the above-mentioned fluids to obtain corresponding signals. The biochemical substance analysis device 100 is used to receive the above-mentioned signals from the first component 1 and analyze the signals to obtain the biological characteristics of the sample in the first component 1. For example, the biological characteristics can be the gene sequence of the sample, that is, the biochemical substance analysis device 100 can be a gene sequencer. It will be understood that the specific type of the biochemical substance analysis device 100 can also be changed according to its actual function.

[0099] As shown in Figure 2, the biochemical substance analysis device 100 includes a second component 2 for assembly with the first component 1. The second component 2 can be a component inherent to the biochemical analysis device 100 itself, and is used to receive the above-mentioned signal from the first component 1 so that the biochemical substance analysis device 100 can analyze the signal. Referring to Figures 3 and 4, in some embodiments, the first component 1 can include a stacked microfluidic chip 1a, a detection chip 1b, and a carrier board 1c. The microfluidic chip 1a is used for fluid to undergo biochemical reactions therein. The detection chip 1b is used to detect the fluid that has reacted in the microfluidic chip 1a and generate corresponding signals. The carrier board 1c is used to assemble with the second component 2 and send the above-mentioned signal to the second component 2. The carrier board 1c can be a circuit board, and a plurality of first electrical connection parts C1 are provided on the plug-in end of the carrier board 1c.

[0100] The second component 2 includes a plug interface 2a, which is provided with a plurality of second electrical connection parts C2. When the plug end of the carrier board 1c is inserted into the plug interface 2a, the first electrical connection part C1 contacts and electrically connects with the second electrical connection part C2, so that the signal at the first component 1 can be sent to the second component 2. The second component 2 can also be connected to a main control board (not shown) through the second electrical connection part C2, so that the above-mentioned signal can be further received by the main control board. The first electrical connection part C1 and the second electrical connection part C2 can be gold fingers or metal contacts. In other embodiments, it is also possible to provide the first component 1 with a plug interface and the second component 2 with a plug end.

[0101] As shown in FIG2 , in some embodiments, the biochemical substance analysis device 100 may further include a heat transfer element 3, which is used to directly or indirectly contact the first component 1 to achieve heat conduction. For example, the heat transfer element 3 can be in direct contact with the first component 1, or it can be in indirect contact with the first component 1 through a thermally conductive adhesive. In this way, heat can be transferred between the first component 1 and the heat transfer element 3. For example, external heat can be transferred to the first component 1 through the heat transfer element 3, and the heat of the first component 1 itself can also be transferred to the outside through the heat transfer element 3, so that the temperature of the first component 1 is controlled within a preset range to ensure the reliability of the biochemical reaction in the first component 1. For example, the setting of the heat transfer element 3 can control the temperature of the first component 1 to fluctuate within the range of ±0.1°C of the preset temperature. The heat transfer element 3 can be a heat transfer platform made of a metal with a high thermal conductivity coefficient.

[0102] The biochemical substance analysis device 100 further includes a loading mechanism 200 for assembling the first component 1 and the second component 2. The loading mechanism 200 includes a base 10, a mounting seat 20, and a loading platform 30.

[0103] 2 , 5 and 6 , the base 10 may be a plate-shaped object, comprising a support surface 11 and a bottom surface 12 disposed opposite to each other in a first direction X. The support surface 11 and the bottom surface 12 are both perpendicular to the first direction X.

[0104] The mounting base 20 is fixed to the support surface 11. The specific fixing method can be screwing, bonding or clamping, etc., which is not limited in this application. The mounting base 20 has a first guide groove 21, and at least part of the first guide groove 21 is inclined relative to the first direction X.

[0105] Referring to Figures 5 to 7 , the loading platform 30 is used to position the first component 1 and the second component 2. In some embodiments, the loading platform 30 includes a first positioning groove 31 and a second positioning groove 32 that communicate with each other. The first positioning groove 31 matches the shape of the first component 1 and is used to position the first component 1 and restrict its movement in the second direction Y. The second positioning groove 32 communicates with the first positioning groove 31 along a second direction Y perpendicular to the first direction X and is used to position the second component 2. The second positioning groove 32 allows the second component 2 to move within the second direction Y. The loading platform 30 is movably disposed on the support surface 11 along the first direction X. In some embodiments, the base 10 further includes a guide shaft 13 disposed on the support surface 11 and extending along the first direction X. The loading platform 30 is provided with a guide hole 34, and the guide shaft 13 is movably inserted into the guide hole 34. The cooperation between the guide hole 34 and the guide shaft 13 enables the loading platform 30 to move strictly along the first direction X, making the movement of the loading platform 30 more stable and smooth. In order to achieve a better guiding effect, the number of the guide shafts 13 and the number of the guide holes 34 can be four, and the four guide holes 34 are respectively located at the four corners of the loading platform 30 .

[0106] The second component 2 is provided with a first guide member 2b that slides within a first guide groove 21. The second component 2 can be assembled to the mounting base 20 via the first guide member 2b. The first guide groove 21 is configured to cooperate with the first guide member 2b, so that when the loading platform 30 moves in the first direction X toward the support surface 11, the second component 2 moves in the second direction Y toward the first component 1 and assembles with the first component 1, bringing C1 and C2 into contact and achieving electrical connection. The first guide groove 21 cooperates with the first guide member 2b to also ensure that when the loading platform 30 moves in the first direction X away from the support surface 11, the second component 2 moves in the second direction Y away from the first component 1 and disengages from the first component 1, separating C1 and C2 and severing the electrical connection. In some specific embodiments, the mounting base 20 may be provided with two first guide grooves 21. Correspondingly, two first guide members 2b are provided on opposite sides of the second component 2, each first guide member 2b slidingly disposed within a first guide groove 21, thereby ensuring smoother and more stable movement of the second component 2. The first guide member 2b may be a columnar structure, but this application does not limit this.

[0107] In this application, if the first component 1 and the second component 2 need to be assembled, the user only needs to place the first component 1 on the loading platform 30 and then manipulate the loading platform 30 to move along the first direction X toward the support surface 11, so that the loading platform 30 drives the first component 1 and the second component 2 toward the support surface 11. Because at least a portion of the first guide groove 21 is tilted relative to the first direction X, during the movement of the loading platform 30, the first guide groove 21 cooperates with the first guide member 2b of the second component 2 to cause the second component 2 to move along the second direction Y toward the first component 1 until the second component 2 is assembled with the first component 1. In other words, this application avoids manually plugging the first component 1 to the second component 2, thereby reducing the risk of wear or even skew of C2 (such as a metal contact) in the second component 2 when the two are misaligned, and improving the stability of electrical signal transmission. Moreover, replacing manual plugging with manipulating the loading platform 30 to move along the first direction X can improve user convenience.

[0108] Similarly, to separate the first component 1 from the second component 2, the user simply moves the loading platform 30 in the first direction X, away from the support surface 11. This causes the loading platform 30 to move the first and second components 1 and 2 away from the support surface 11. During the movement of the loading platform 30, the first guide groove 21 cooperates with the first guide member 2b to move the second component 2 in the second direction Y, away from the first component 1, until the second component 2 separates from the first component 1. This eliminates the need for manual extraction to separate the first component 1 from the second component 2, further enhancing user convenience.

[0109] Referring to Figures 5, 6, and 8, in some embodiments, the first guide slot 21 includes a first section 211 that is tilted relative to the first direction X. The first section 211 includes a first end 2111 and a second end 2112 that are oppositely disposed. The first end 2111 is located between the support surface 11 and the second end 2112 in the first direction X, i.e., the first end 2111 is positioned lower than the second end 2112. The first end 2111 is closer to the first positioning slot 31 than the second end 2112 in the second direction Y. When the first guide member 2b slides from the second end 2112 toward the first end 2111, the second component 2 gradually approaches the first positioning slot 31 and the first component 1 located therein, until the first component 1 and the second component 2 are assembled. Conversely, when the first guide member 2b slides from the first end 2111 toward the second end 2112, the second component 2 gradually moves away from the first positioning slot 31 and the first component 1 located therein, until the first component 1 and the second component 2 are separated.

[0110] Furthermore, the first guide groove 21 may also include a second section 212 connected to the first end 2111 and a third section 213 connected to the second end 2112. Specifically, the second section 212 is positioned lower than the third section 213. Both the second section 212 and the third section 213 extend along the first direction X. When the first guide member 2b slides to the second section 212, the first component 1 and the second component 2 are assembled; when the first guide member 2b slides to the third section 213, the first component 1 and the second component 2 are separated. The first section 211, the second section 212, and the third section 213 may all be linear grooves. In other embodiments, the second section 212 and the third section 213 may also be omitted, that is, the first guide groove 21 only includes the first section 211. In this case, when the first guide member 2b slides to the first end 2111 of the first section 211, the first component 1 is assembled with the second component 2; when the first guide member 2b slides to the second end 2112 of the first section 211, the first component 1 is disengaged from the second component 2.

[0111] As shown in Figures 6 and 7, in some embodiments, the mounting base 20 further includes a second guide groove 22, at least a portion of which is inclined relative to the first direction X. The loading mechanism 200 also includes a stopper 40 movably disposed on the loading platform 30. The loading platform 30 may also include a third positioning groove 33, which communicates with the first positioning groove 31 along a third direction Z perpendicular to both the first direction X and the second direction Y. The third positioning groove 33 is used to accommodate the stopper 40 and allows the stopper 40 to move within the third direction Z. The stopper 40 is provided with a second guide member 40a slidably disposed within the second guide groove 22. The second guide groove 22 is configured to cooperate with the second guide member 40a, so that when the loading platform 30 moves toward the support surface 11 along the first direction X, the stopper 40 moves toward the first positioning groove 31 along the third direction Z until the stopper 40 moves above the first positioning groove 31. At this time, when viewed from the first direction X, the limiter 40 overlaps with the first positioning groove 31. When the limiter 40 moves to above the first positioning groove 31, the limiter 40 can limit the movement of the first component 1 in the first direction X, thereby fixing the first component 1. In some specific embodiments, the loading mechanism 200 includes two limiters 40 arranged opposite to each other in the third direction Z, so as to provide a more uniform limiting force to the first component 1. Furthermore, the mounting seat 20 can be provided with two second guide grooves 22 corresponding to each limiter 40, and correspondingly, two second guide members 40a are provided on opposite sides of each limiter 40, and each second guide member 40a is slidably arranged in a second guide groove 22, so that the movement of the limiter 40 is more stable and smooth. The second guide member 40a can be a columnar structure, but this application does not limit it. The limiter 40 can be a block structure, but this application does not limit it.

[0112] With reference to Figures 6, 8, and 10, the mounting base 20 may include a first mounting portion 20a and two second mounting portions 20b disposed opposite each other in a third direction Z. The first mounting portion 20a is disposed between the two second mounting portions 20b. A first guide groove 21 is disposed in the first mounting portion 20a, and a second guide groove 22 is disposed in the second mounting portion 20b. The loading platform 30 is at least partially disposed within the space enclosed by the first mounting portion 20a and the second mounting portion 20b.

[0113] As shown in Figures 9 and 10, the specific structure of the second guide groove 22 can be similar to that of the first guide groove 21. The second guide groove 22 includes a fourth section 221, which is arranged at an angle relative to the first direction X. The fourth section 221 includes a third end 2211 and a fourth end 2212, which are arranged opposite each other. The third end 2211 is located between the support surface 11 and the fourth end 2212 in the first direction X, that is, the third end 2211 is located lower than the fourth end 2212. The third end 2211 is closer to the first positioning groove 31 than the fourth end 2212 in the third direction Z. As the second guide member 40a slides from the fourth end 2212 to the third end 2211, the limiting member 40 gradually approaches the first positioning groove 31 and the first component 1 located within the first positioning groove 31 until the limiting member 40 restricts the movement of the first component 1 in the first direction X. On the contrary, when the second guiding member 40 a slides from the third end 2211 to the fourth end 2212 , the limiting member 40 gradually moves away from the first positioning groove 31 and the first component 1 located in the first positioning groove 31 until the limiting member 40 releases the first component 1 .

[0114] Furthermore, the second guide groove 22 may further include a fifth section 222 connected to the third end 2211 and a sixth section 223 connected to the fourth end 2212. Specifically, the fifth section 222 is positioned lower than the sixth section 223. Both the fifth section 222 and the sixth section 223 extend along the first direction X. When the second guide member 40a slides to the fifth section 222, the stopper 40 restricts movement of the first component 1 in the first direction X. When the second guide member 40a slides to the sixth section 223, the stopper 40 releases the first component 1. In other embodiments, the fifth section 222 and the sixth section 223 may be omitted.

[0115] On the one hand, the limiting member 40 can be arranged to extend and move to the top of the first component 1 first, and then the second component 2 can be extended, so that the position of the first component 1 is fixed when the first component 1 and the second component 2 are assembled, ensuring the smoothness and reliability of the assembly process. In order to achieve the second component 2 extending after the limiting member 40 moves to the top of the first component 1, as shown in Figure 5, the fourth section 221 of the second guide groove 22 can be arranged to be higher than the first section 211 of the first guide groove 21 (the cross-section in Figure 5 only cuts through the third end 2211 of the fourth section 221), that is, in the first direction X, the third end 2211 of the fourth section 221 is farther away from the support surface 11 than the second end 2112 of the first section 211.

[0116] On the other hand, as shown in Figures 6 and 7, the base 10 is provided with a first window 14 that passes through the support surface 11 and the bottom surface 12, and the loading platform 30 is provided with a second window 35 that passes through the bottom of the first positioning groove 31. When viewed from the first direction X, the first window 14 and the second window 35 overlap, and the first window 14 and the second window 35 are used to allow the heat transfer element 3 to pass through. Specifically, the heat transfer element 3 may include a first heat transfer portion 3a and a second heat transfer portion 3b that are connected. When viewed from the first direction X, the area of ​​the first heat transfer portion 3a is larger than the area of ​​the second heat transfer portion 3b. Please refer to Figure 5 as well. The first heat transfer portion 3a is provided on one side of the bottom surface 12 of the base 10 and is set apart from the bottom surface 12. The second heat transfer portion 3b extends from the first heat transfer portion 3a and passes through the first window 14 and the second window 35. Since the limiting member 40 can limit the movement of the first component 1 in the first direction X, it can ensure that the second heat transfer portion 3b of the heat transfer member 3 is in direct or indirect contact with the first component 1 to achieve heat conduction, and since the first heat transfer portion 3a is set at a distance from the bottom surface 12, it is also beneficial for the heat transfer member 3 to conduct heat away. In the related art, the detection chip is inserted into the card holder by manual plugging, and then the card holder is pressed to rotate it to the original position after the plugging is completed, and then the position of the detection chip is locked by a structure such as a lock. However, the detection chip may bend under the pressure of the lock, causing the plug-in end of the detection chip to act on the metal contact in the card holder, thereby causing the metal contact to wear or even bend, and poor heat conduction occurs between the bent detection chip and the heat transfer member. Some embodiments of the present application control the limiting member 40 to extend along the third direction Z instead of being pressed along the first direction X, so that the first component 1 will not have the problem of bending and deformation, thereby ensuring the reliability of the conduction of electrical signals and heat.

[0117] With reference to Figures 2, 6, and 11, in some embodiments, the loading mechanism 200 further includes an operating member 50, comprising a rotating portion 51 rotatably connected to the mounting base 20 via a first rotating shaft S1. The rotating portion 51 is also connected to the loading platform 30. For example, a transmission portion 36 is provided on the outer side of the loading platform 30, and a first sliding groove 23 extending along the first direction X is provided on the second mounting portion 20b of the mounting base 20. The transmission portion 36 movably passes through the first sliding groove 23 and is connected to the rotating portion 51. The rotating portion 51 is configured to drive the loading platform 30 toward the support surface 11 along the first direction X when the rotating portion 51 rotates relative to the mounting base 20. During the movement of the loading platform 30 toward the support surface 11 along the first direction X, the transmission portion 36 slides along the first sliding groove 23. Therefore, a user can rotate the rotating portion 51 relative to the mounting base 20, thereby manipulating the loading platform 30 to move along the first direction X toward the support surface 11. More specifically, to apply a more uniform transmission force to the loading platform 30, the operating member 50 may include two opposing rotating portions 51. Correspondingly, two transmission portions 36 may be provided on opposing outer sides of the loading platform 30, each transmission portion 36 being connected to one of the rotating portions 51. Therefore, when the two rotating portions 51 rotate relative to the mounting base 20, the two transmission portions 36 drive the loading platform 30 to move along the first direction X toward the support surface 11, allowing the loading platform 30 to move more smoothly.

[0118] Furthermore, the rotating portion 51 can be a strip-shaped structure and can be provided with a second sliding groove 51a extending along the extension direction of the rotating portion 51. The transmission portion 36 is slidably disposed within the second sliding groove 51a, thereby connecting the transmission portion 36 to the rotating portion 51. As the loading platform 30 moves along the first direction X toward the support surface 11, the transmission portion 36 can slide within the second sliding groove 51a, thereby preventing the rotation of the rotating portion 51 from being obstructed when the transmission portion 36 is fixedly connected to the rotating portion 51. The second sliding groove 51a can be a waist-shaped hole.

[0119] The operating member 50 may further include an operating portion 52 connected to the rotating portion 51. When the operating portion 52 includes two rotating portions 51, the operating portion 52 is connected between the two rotating portions 51. The user can press the operating portion 52 to control the rotation of the rotating portion 51. The operating portion 52 and the rotating portion 51 may be generally bar-shaped components, and the operating member 50 as a whole may be a U-shaped handle. In this case, the operating portion 52 acts like a lever, thereby achieving the purpose of saving effort.

[0120] In some embodiments, the operating member 50 also includes a first elastic member 53, which is elastically connected to the mounting seat 20 and the rotating portion 51. During the process of rotating the operating member 50 to move the loading platform 30 along the first direction X toward the support surface 11, the first elastic member 53 is in a compressed state. When the operating member 50 is subsequently rotated in the opposite direction to move the loading platform 30 away from the support surface 11 along the first direction X, the elastic restoring force of the first elastic member 53 is used to maintain the operating portion 52 in the desired position (such as maintaining it at the highest point). In some embodiments, the number of the first elastic members 53 can be two, and the two first elastic members 53 are respectively located on both sides of the mounting seat 20 in the third direction Z. Among them, the first elastic member 53 can be a torsion spring, which includes a first arm 531 and a second arm 532, the first arm 531 is connected to the mounting seat 20, that is, the first wall 531 is fixed in position, and the second arm 532 is connected to the rotating portion 51.

[0121] With reference to Figures 6 and 12 , in some embodiments, the loading mechanism 200 further includes a locking member 60 mounted on the base 10. The locking member 60 is used to lock the operating portion 52, thereby maintaining the operating portion 50 in a desired position. The locking member 60 may include a base 61 fixed to the base 10 and a locking portion 62 rotatably connected to the base 61 via a second rotation axis S2. The locking portion 62 is used to lock the operating portion 52. Furthermore, the locking portion 62 includes a body 621 rotatably connected to the base 61 and a tongue 622 protruding from the body 621. The tongue 622 includes a locking surface 6220 perpendicular to the plane of the body 621. The locking surface 6220 is used to lock the operating portion 52 when parallel to the support surface 11. More specifically, as shown in Figure 11 , the operating portion 52 is provided with a recess 52a. The tongue 622 is adapted to fit within the recess 52a, with the locking surface 6220 abutting against the bottom surface 12 of the recess 52a.

[0122] In some embodiments, the tongue portion 622 may further include an inclined surface 6221 disposed opposite the locking surface 6220. In the first direction X, the inclined surface 6221 is further away from the support surface 11 than the locking surface 6220. The inclined surface 6221 is inclined relative to the support surface 11. When the operating member 50 rotates toward the base 10, the operating portion 52 acts on the inclined surface 6221, causing the locking member 60 to rotate away from the operating portion 52, thereby pressing the operating portion 52 to its lowest point. The locking member 60 also includes a second elastic member 63, which is configured to abut against the body 621. When the locking member 60 rotates away from the operating portion 52 under the action of the operating portion 52, the second elastic member 63 is in a compressed state. Its elastic restoring force serves to reset the locking member 60 (i.e., rotate the locking member 60 toward the operating portion 52), thereby causing the locking surface 6220 to become parallel to the support surface 11, thereby locking the operating portion 52. Among them, the second elastic member 63 can be a torsion spring mounted on the second rotating shaft S2, which includes a third arm 631 and a fourth arm 632. The third arm 631 is elastically supported on the main body 621, and the position of the fourth arm 632 is fixed (for example, the fourth arm 632 can be elastically supported on the horizontal plane supporting the loading mechanism 200).

[0123] As shown in Figures 2 and 5, in some embodiments, the base 10 further includes a third elastic member 15 wound around each guide shaft 13. The third elastic member 15 elastically abuts against the support surface 11 and the loading platform 30. The third elastic member 15 is used to eliminate the play gap that occurs when the loading platform 30 moves along the first direction X until the first component 1 directly or indirectly contacts the heat transfer element 3. The third elastic member 15 can be a helical cylindrical spring.

[0124] In summary, the working principle of the loading mechanism 200 of the present application is as follows: Referring to Figures 13 and 14, the user manually places the first component 1 in the first positioning groove 31 of the loading platform 30, and then presses the operating portion 52 of the operating member 50 to rotate the operating member 50 toward the base 10. At this time, the operating member 50 transmits downward pressure to the loading platform 30 through the transmission portion 36 provided on the outer side of the loading platform 30, causing the loading platform 30 to move toward the support surface 11 along the first direction X. During the process of the loading platform 30 moving toward the support surface 11 along the first direction X, the limiting member 40 slides within the second guide groove 22 via the second guide member 40a (shown in Figures 6 and 7). The cooperation between the second guide groove 22 and the second guide member 40a causes the limiting member 40 to move along the third direction Z toward the first positioning groove 31 until the limiting member 40 moves above the first positioning groove 31 and restricts the movement of the first component 1 in the first direction X. Next, the second component 2 slides within the first guide groove 21 via the first guide member 2b (shown in Figures 3 and 5). The cooperation between the first guide groove 21 and the first guide member 2b causes the second component 2 to move toward the first component 1 along the second direction Y and assemble with the first component 1. When the operating portion 52 is pressed until it contacts the inclined surface 6221 of the locking member 60, the locking member 60 rotates away from the operating portion 52. When the operating portion 52 is pressed to its lowest point, the first component 1 directly or indirectly contacts the heat transfer member 3, achieving heat transfer. At this point, the locking member 60 is reset under the action of the second elastic member 63, locking the operating portion 52 and maintaining the operating member 50 in the desired position.

[0125] After the inspection is complete, the locking member 60 can be rotated away from the operating portion 52 to release the operating portion 52. At this point, the operating portion 52 can be rotated to rotate the operating member 50 away from the base 10. The operating member 50 then transmits an upward thrust to the loading platform 30 via the transmission portion 36 disposed outside the loading platform 30, causing the loading platform 30 to move in the first direction X away from the support surface 11. As the loading platform 30 moves in the first direction X away from the support surface 11, the second component 2 slides within the first guide groove 21 via the first guide member 2b. The interaction between the first guide groove 21 and the first guide member 2b causes the second component 2 to move in the second direction Y away from the first component 1 and disengage from the first component 1. Subsequently, the limiting member 40 slides within the second guide groove 22 via the second guide member 40a. The interaction between the second guide groove 22 and the second guide member 40a causes the limiting member 40 to move in the third direction Z away from the first positioning groove 31 until the limiting member 40 releases its restraint on the first component 1. Then, the first component 1 located in the first positioning groove 31 can be taken out.

[0126] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application and are not intended to limit the present application. Although the present application has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present application may be modified or replaced by equivalents without departing from the spirit and scope of the technical solutions of the present application.

Claims

1. A loading mechanism configured to assemble a first component with a second component, characterized in that: The loading mechanism comprises: A base including a support surface, defining a first direction perpendicular to the support surface; A mounting seat fixed on the support surface, the mounting seat being provided with a first guide groove, at least a portion of the first guide groove being inclined relative to the first direction; and The loading platform is configured to place the first component and the second component, and is movably arranged on the support surface along the first direction. The second component is provided with a first guide member slidably arranged in the first guide groove. The first guide groove is configured to cooperate with the first guide member, so that when the loading platform moves toward the support surface along the first direction, the second component moves toward the first component along a second direction perpendicular to the first direction and is assembled with the first component.

2. The loading mechanism according to claim 1, wherein: The first guide groove is further configured to cooperate with the first guide member so that when the loading platform moves away from the support surface along the first direction, the second component moves away from the first component along the second direction and disengages from the first component.

3. The loading mechanism according to claim 1, wherein: The loading platform includes a first positioning groove and a second positioning groove that are connected to each other. The first positioning groove is configured to place the first component, the second positioning groove is configured to place the second component, and the second positioning groove is configured to allow the second component to move along the second direction.

4. The loading mechanism according to claim 3, wherein: The first guide groove includes a first section that is inclined compared to the first direction, and the first section includes a first end and a second end that are oppositely arranged. The first end is located between the support surface and the second end in the first direction, and the first end is closer to the first positioning groove than the second end in the second direction.

5. The loading mechanism according to claim 4, wherein: The first guide groove further includes a second section connected to the first end portion and a third section connected to the second end portion, and both the second section and the third section extend along the first direction.

6. The loading mechanism according to claim 4, wherein: The mounting seat is also provided with a second guide groove, at least part of which is inclined compared to the first direction. The loading mechanism also includes a limiting member provided on the loading platform, and the limiting member is provided with a second guide member slidably provided in the second guide groove. The second guide groove is configured to cooperate with the second guide member so that when the loading platform moves along the first direction toward the supporting surface, the limiting member moves toward the first positioning groove along a third direction perpendicular to both the first direction and the second direction.

7. The loading mechanism according to claim 6, wherein: The second guide groove includes a fourth section that is inclined compared to the first direction, and the fourth section includes a third end and a fourth end that are oppositely arranged. The third end is located between the support surface and the fourth end in the first direction, and the third end is closer to the first positioning groove than the fourth end in the third direction.

8. The loading mechanism according to claim 7, wherein: In the first direction, the third end is farther away from the support surface than the second end.

9. The loading mechanism according to claim 6, wherein: The loading platform further includes a third positioning groove communicated with the first positioning groove, the third positioning groove is configured to accommodate the limiting member, and the third positioning groove is configured to allow the limiting member to move along the third direction.

10. The loading mechanism according to claim 3, wherein: The base is provided with a first window passing through the supporting surface, and the loading platform is provided with a second window passing through the first positioning groove. When viewed from the first direction, the first window and the second window overlap. The first window and the second window are configured to allow a heat transfer element to pass through, so that heat conduction is achieved between the heat transfer element and the first component.

11. The loading mechanism according to claim 1, wherein: The loading mechanism further includes an operating member, which includes a rotating portion rotatably connected to the mounting seat. The rotating portion is also connected to the loading platform, and the rotating portion is configured to drive the loading platform to move along the first direction when rotating relative to the mounting seat.

12. The loading mechanism according to claim 11, wherein: A transmission part is provided on the outer side of the loading platform, and the mounting seat is provided with a first sliding groove extending along the first direction. The transmission part can movably pass through the first sliding groove and be connected to the rotating part.

13. The loading mechanism according to claim 12, wherein: The rotating part is provided with a second sliding groove extending along an extending direction of the rotating part, and the transmission part is slidably arranged in the second sliding groove.

14. The loading mechanism according to claim 11, wherein: The operating member further includes a first elastic member connected to the mounting seat and the rotating portion.

15. The loading mechanism according to claim 14, wherein: The first elastic member includes a first arm and a second arm, the first arm is connected to the mounting seat, the second arm is connected to the rotating part, and the first elastic member is configured to be in a compressed state when the rotating part drives the loading platform to move along the first direction toward the support surface.

16. The loading mechanism according to claim 11, wherein: The operating member further includes an operating portion connected to the rotating portion, and the operating portion is configured to drive the rotating portion to rotate when pressed.

17. The loading mechanism according to claim 16, wherein: The loading mechanism further includes a locking member mounted on the base, wherein the locking member is configured to lock the operating portion.

18. The loading mechanism according to claim 17, wherein: The locking member includes a seat body fixed to the base and a locking portion rotatably connected to the seat body, and the locking portion is configured to lock the operating portion.

19. The loading mechanism according to claim 18, wherein: The locking portion includes a main body rotatably connected to the seat and a tongue protruding from the main body, the tongue includes a locking surface perpendicular to the plane where the main body is located, and the locking surface is configured to lock the operating portion when parallel to the supporting surface.

20. The loading mechanism according to claim 19, wherein: The tongue portion also includes an inclined surface that is inclined relative to the supporting surface. In the first direction, the inclined surface is farther away from the supporting surface than the locking surface. The operating portion is configured to abut against the inclined surface when pressed, so that the locking member rotates away from the operating portion; the locking member also includes a second elastic member, which is configured to abut against the main body and is elastically deformed when the locking member rotates away from the operating portion. The elastic restoring force of the second elastic member causes the locking surface to lock the operating portion.

21. The loading mechanism according to claim 20, wherein: The second elastic member includes a third arm and a fourth arm. The third arm is elastically supported on the body, and the position of the fourth arm is fixed.

22. The loading mechanism according to claim 1, wherein: The base further includes a guide shaft provided on the supporting surface, the guide shaft extending along the first direction, the loading platform is provided with a guide hole, and the guide shaft can be movably inserted into the guide hole.

23. The loading mechanism according to claim 22, wherein: The base further includes a third elastic member wound around the guide shaft, and the third elastic member elastically abuts against the supporting surface and the loading platform.

24. The loading mechanism according to claim 6, wherein: The mounting seat includes a first mounting portion and two oppositely arranged second mounting portions, the first mounting portion is arranged between the two second mounting portions, the first guide groove is arranged on the first mounting portion, the second guide groove is arranged on the second mounting portion, and the loading platform is at least partially arranged in the space formed by the first mounting portion and the second mounting portion.

25. A biochemical substance analysis device, comprising a second component, characterized in that: The biochemical substance analysis device further includes a loading mechanism according to any one of claims 1 to 24, wherein the second component is disposed on a loading platform of the loading mechanism.

26. The biochemical substance analysis device according to claim 25, wherein: The biochemical substance analysis device further includes a heat transfer element, which is at least partially disposed through the base and the loading platform, and is configured to directly or indirectly contact the first component to achieve heat conduction.

27. A biochemical substance analysis system, comprising a first component, characterized in that: The biochemical substance analysis system further includes the biochemical substance analysis device according to claim 25 or 26, wherein the first component is configured to be placed on a loading station of a loading mechanism of the biochemical substance analysis device and assembled with the second component.

28. The biochemical substance analysis system according to claim 27, wherein: The first component includes a microfluidic chip, a detection chip and a carrier plate stacked in the first direction, the detection chip is configured to detect the fluid in the microfluidic chip and generate a corresponding signal, and the carrier plate is configured to be assembled with the second component and send the signal to the second component.

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