Interbody fusion cage and manufacturing method thereof

By designing a support and connecting structure along the load-bearing direction in the interbody fusion cage, incorporating a built-in vascular channel network and pre-cultivating artificial blood vessels, the problems of insufficient nutrient delivery and disordered osteoblast growth in existing porous titanium alloy interbody fusion cages are solved, achieving rapid and efficient bone integration and fusion.

CN122272249AActive Publication Date: 2026-06-26SUZHOU & SCI & TECH DEV
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Patent Information

Application Number
CN202610645429.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-05-12
Publication Date
2026-06-26
Estimated Expiration
2046-05-12

AI Technical Summary

Technical Problem

Existing 3D-printed porous titanium alloy interbody fusion devices lack a channel design specifically for the directional delivery of nutrients, resulting in nutrient deficiency and accumulation of metabolic waste in deep cells, as well as disordered osteoblast growth, leading to low fusion efficiency and insufficient fusion strength.

Method used

A support and connecting structure along the load-bearing direction was designed, with an internal vascular channel network including a main channel and multi-level branch channels. The support surface has grooves, and the support interior has a vascular channel network. The inner wall is coated with a bio-modified layer and pre-cultured artificial blood vessels. The intervertebral fusion device was fabricated using 3D printing and biomimetic cultivation technology.

Benefits of technology

It enables osteoblasts to grow in a directional manner along the load-bearing direction, ensuring a continuous supply of nutrients and removal of metabolic waste from deep cells, significantly accelerating the bone integration process, improving fusion strength and efficiency, and reducing the risk of postoperative loosening and displacement.

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Abstract

The invention provides an interbody fusion cage which comprises a plurality of supporting bodies and a plurality of connecting bodies used for connecting the supporting bodies, the supporting bodies are arranged at intervals, the connecting bodies are connected with the adjacent supporting bodies, and the supporting bodies extend in the bearing direction. The outer surfaces of the supporting bodies are concaved inwards to form grooves extending in the bearing direction, a blood vessel channel network is arranged in each supporting body in advance, each blood vessel channel network comprises a main channel and multiple stages of branch channels, the two ends of each main channel penetrate through the upper surface and the lower surface of the corresponding supporting body in the bearing direction respectively, and the multiple stages of branch channels are communicated with the main channels. One end of the branch channel is communicated with the main channel, and the other end of the branch channel extends to the groove. According to the interbody fusion cage, bone cells can be guided to directionally grow in the bearing direction, immediate blood perfusion and global nutrition delivery during implantation are achieved, and the problems that a traditional fusion cage is insufficient in deep nutrition, disordered in bone growth and low in fusion efficiency are solved.
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