Benzocyclo[1,2]oxaborol-1(3H)-ol derivatives as SHP2 inhibitors, compositions and methods thereof

By developing novel phosphine oxide compounds as SHP2 inhibitors, the problems of insufficient safety and efficacy in existing technologies have been solved, enabling the application of these compounds in drug development. These compounds exhibit good pharmacokinetic properties and therapeutic effects.

CN122295347APending Publication Date: 2026-06-26CANWELL BIOTECH LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
CANWELL BIOTECH LTD
Filing Date
2024-10-09
Publication Date
2026-06-26

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Abstract

This invention provides a novel phosphine oxide compound that inhibits SHP2, a composition thereof, a method for preparing the compound, and a method for treating SHP2-related diseases (such as cancer).
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