A traditional Chinese medicine ointment acupoint patch for treating hot cough and a preparation method thereof

Abstract

This invention discloses a traditional Chinese medicine ointment acupoint patch for treating febrile cough and its preparation method, belonging to the field of external treatment technology of traditional Chinese medicine. The acupoint patch includes a pre-loaded medicated cake and a medical adhesive tape carrier. The medicated cake is composed of active traditional Chinese medicine powder dispersed in an oily molding matrix. The active traditional Chinese medicine powder is composed of Asarum, Euphorbia kansui, Corydalis, Sinapis alba, Pinellia ternata, camphor, and borneol in a mass ratio of 10:10:10:10:5:4:1, and pulverized to 100-150 mesh. The oily molding matrix is ​​made of ginger juice, traditional Chinese medicine oil, and beeswax in a mass ratio of 8:1:1. The preparation method includes: preparing the above powder and matrix, mixing them, forming them into pills, pressing them into cakes, and assembling them onto a breathable adhesive tape with an impermeable ring. The patch of this invention, through a specific formulation, focuses on the effects of clearing phlegm and heat, and relieving sore throat. Combined with the ointment matrix, it reduces skin irritation. The impermeable ring structure enables precise drug positioning, providing a convenient and low-side-effect new external treatment option for febrile cough.

Description

Technical Field

[0001] This invention relates to the field of external treatment technology of traditional Chinese medicine, and more specifically, to a topical preparation for acupoint application, particularly a traditional Chinese medicine patch for treating feverish cough, having a specific drug composition and ointment matrix structure, and its preparation process. Background Technology

[0002] In the field of external treatment of traditional Chinese medicine, acupoint application therapy is widely used for the prevention and treatment of diseases such as cough due to its ease of use and minimal side effects. Currently, most commercially available cough-relieving acupoint application preparations are made by mixing Chinese medicine powder with water-based or viscous bases, such as honey, petrolatum, or modern polymer gels, and then directly applying or pressing them into patches.

[0003] However, these existing patches still have several significant drawbacks in practical applications. First, their matrix selection often focuses on the function of adhesion and carrying medicinal powder, with insufficient consideration for skin compatibility and irritation. Especially for cough treatment that requires prolonged application, this can easily cause local skin rashes, itching, or even allergic reactions, resulting in poor patient tolerance. Second, many patches have limited transdermal drug absorption efficiency, resulting in a superficial effect and difficulty in maintaining a sustained and stable drug penetration, thus affecting efficacy. Third, the carrier design of traditional plasters is relatively simple, lacking effective restraint of drug components. Under body temperature, the plaster easily softens and spreads, staining clothing and preventing the drug from concentrating on the target acupoint area, affecting the accuracy of treatment. In addition, considering the characteristics of cough diagnosis and treatment, existing patches are mostly general formulas. When targeting the specific syndrome of "heat cough," their formulations are often not precise enough, lacking strong targeting for warming and resolving phlegm and penetrating the meridians, leading to inconsistent clinical effects.

[0004] Therefore, developing a traditional Chinese medicine acupoint patch preparation that can take into account good skin tolerance, long-lasting and stable drug release, precise drug positioning and target the pathogenesis of feverish cough remains a technical problem that urgently needs to be solved in this field. Summary of the Invention

[0005] The purpose of this section is to outline some aspects of the embodiments of the present invention and to briefly introduce some preferred embodiments. Some simplifications or omissions may be made in this section, as well as in the specification abstract and the title of the invention, to avoid obscuring the purpose of this section, the specification abstract, and the title of the invention. Such simplifications or omissions shall not be used to limit the scope of the invention.

[0006] In view of the problems existing in the above and / or prior art, the present invention is proposed.

[0007] This invention aims to overcome the above-mentioned defects of the prior art and provide a traditional Chinese medicine ointment acupoint patch for treating febrile cough that is highly targeted, has low skin irritation, precise drug positioning, and definite curative effect, as well as its preparation method.

[0008] To achieve the above objectives, this invention first provides a traditional Chinese medicine ointment acupoint patch for treating feverish cough. The patch's overall structure includes a pre-loaded medicinal cake and a medical adhesive tape carrier for fixing the medicinal cake, thus forming a ready-to-use complete treatment unit. The pre-loaded medicinal cake is composed of active traditional Chinese medicine powder uniformly dispersed in an oil-based molding matrix. The innovation and efficacy of this invention primarily stem from the specific composition and synergistic design of its core materials.

[0009] The active powder of traditional Chinese medicine described in this invention is composed of Asarum, Euphorbia kansui, Corydalis yanhusuo, Sinapis alba, Pinellia ternata, camphor, and borneol in a precise mass ratio of 10:10:10:10:5:4:1. This formula contains the core substances that produce therapeutic effects. Euphorbia kansui, Pinellia ternata, and Sinapis alba are combined to focus on clearing phlegm, eliminating dampness, and resolving stagnation, targeting cough caused by phlegm stagnation. Asarum and Corydalis yanhusuo work synergistically to promote qi circulation and relieve discomfort caused by coughing. Borneol and camphor penetrate and open the orifices, clear heat and soothe the throat, helping to relieve symptoms such as redness, swelling, heat, and pain in the throat, and guiding the effects of the other herbs deeper. The synergistic effect of these herbs in this specific ratio focuses on resolving phlegm, clearing the throat, and dispersing heat stagnation, thereby correspondingly relieving symptoms such as cough and throat discomfort. To ensure the release rate and transdermal efficiency of the active ingredients, the particle size of the active powder of traditional Chinese medicine is limited to between 100 and 150 mesh.

[0010] The oily molding matrix is ​​composed of ginger juice, specially formulated Chinese herbal oil, and beeswax in a mass ratio of 8:1:1, which is key to achieving low irritation and long-lasting efficacy. The Chinese herbal oil is an oily substance extracted from angelica, rehmannia root, and purple gromwell root by frying in sesame oil; it possesses both medicinal efficacy and good skin compatibility. In this specific matrix system, ginger juice acts as a pungent and penetrating agent, the Chinese herbal oil moisturizes and reduces irritation, and beeswax provides suitable shaping ability and sustained-release properties. The three work synergistically to fundamentally improve the shortcomings of traditional patches, such as easy skin allergies and short-lasting efficacy.

[0011] In terms of the specific form of the product, the pre-loaded medicated cake is constructed into a circular, thin cake shape with a diameter between 13mm and 17mm and a thickness between 1mm and 2mm. This size range ensures effective coverage of commonly used acupoint areas while maintaining good adhesion. As a proven preferred option, the diameter of the pre-loaded medicated cake can be specifically 15mm, which achieves a better balance between coverage area, medication dosage, and skin comfort. The medical adhesive tape carrier is preferably a breathable adhesive tape with an anti-leakage ring, within which the pre-loaded medicated cake is placed. This structural design effectively prevents drug leakage, ensuring that the drug's potency is concentrated on the target acupoint skin, thereby improving the accuracy and hygiene of the treatment. The carrier material can be further preferably a non-woven adhesive tape or a PU film adhesive tape.

[0012] To achieve the preparation of the above-mentioned product, the present invention also provides a supporting preparation method. The method includes: Step 1, preparing the specific proportion and particle size of the traditional Chinese medicine active powder; Step 2, preparing the traditional Chinese medicine oil by soaking Angelica sinensis and Rehmannia glutinosa in sesame oil, frying them until they turn yellow, and then adding Lithospermum erythrorhizon for further frying, wherein the amount of sesame oil is preferably 3-5 times the total mass of the medicinal materials; Step 3, mixing ginger juice, the prepared traditional Chinese medicine oil, and beeswax strictly in a ratio of 8:1:1, and heating to prepare an oily molding matrix; Step 4, mixing the powder and the matrix, and blending them uniformly at a preferred temperature of 45℃ to 55℃, and then forming spherical pills with a diameter between 0.8cm and 1.2cm as an intermediate; as a preferred standardized production scheme, the diameter of the spherical pills can be specifically 1cm to facilitate precise control of the final dosage form and weight of the medicinal cake. Step 5: Press the spherical pills into circular patches of the specified thickness and diameter; Step 6: Assemble the patches into a breathable medical adhesive tape carrier with an impermeable ring to complete the patch preparation.

[0013] In use, the patch of this invention exerts its therapeutic effect by being applied to acupoints such as Tian Tu, Tan Zhong, and Da Zhui. Its mechanism of action lies in: a specific ointment matrix ensures gentle drug release and significantly reduces skin irritation; an impermeable ring carrier structure enables precise drug targeting and sustained action; and the well-chosen compound formulation allows for transdermal absorption, directly exerting its pharmacological effects of warming and resolving phlegm, and relieving cough. The organic combination of these three factors constitutes the fundamental reason for its definite efficacy and good tolerability in treating heat-related coughs.

[0014] In summary, this invention provides a safe, effective, and convenient new option for external treatment by systematically combining syndrome differentiation and formulation, innovative matrix, precise carrier, and standardized process.

[0015] This invention fundamentally enhances the overall performance of the patch by combining carefully selected compound components, an innovative ointment matrix, and a leak-proof carrier structure. The specifically formulated herbal powders ensure a precise therapeutic effect against heat-related coughs; the ointment matrix, composed of ginger juice, herbal oil, and beeswax in an 8:1:1 ratio, significantly reduces skin irritation and improves medication safety and tolerability; while the breathable adhesive tape carrier with a leak-proof ring ensures precise application of the medication to acupoints without leakage, making treatment more convenient and hygienic. Furthermore, standardized patch size and a clear manufacturing process guarantee stable and consistent product quality. This invention integrates high efficiency, safety, convenience, and stability, providing an ideal external treatment option for heat-related coughs. Attached Figure Description

[0016] To more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the following description of the embodiments will be briefly introduced. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0017] Figure 1 This is a schematic diagram of the overall structure of the herbal ointment acupoint patch of the present invention; Figure 2 This is a schematic diagram illustrating the usage of the herbal ointment acupoint patch of the present invention; Figure 3 This is a flowchart of the preparation process.

[0018] in: 100 is a traditional Chinese medicine ointment for acupoint application, 10 is a pre-loaded medicated cake, 20 is a medical adhesive tape carrier, 21 is a leak-proof ring, and 30 is release paper. Detailed Implementation

[0019] To make the above-mentioned objects, features and advantages of the present invention more apparent and understandable, the specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

[0020] Many specific details are set forth in the following description in order to provide a full understanding of the invention. However, the invention may also be practiced in other ways different from those described herein, and those skilled in the art can make similar extensions without departing from the spirit of the invention. Therefore, the invention is not limited to the specific embodiments disclosed below.

[0021] Secondly, the present invention will be described in detail with reference to the schematic diagrams. When detailing the embodiments of the present invention, for ease of explanation, the cross-sectional views illustrating the device structure will be partially enlarged, not according to the usual scale. Furthermore, the schematic diagrams are merely examples and should not limit the scope of protection of the present invention. In addition, actual fabrication should include three-dimensional spatial dimensions of length, width, and depth.

[0022] Furthermore, the term "an embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The phrase "in one embodiment" appearing in different places throughout this specification does not necessarily refer to the same embodiment, nor is it a single or selective embodiment that mutually excludes other embodiments. Example

[0023] The present invention provides a traditional Chinese medicine ointment acupoint patch 100 for treating feverish cough; the product structure can be found in [reference needed]. Figure 1The acupoint patch 100 is generally composed of two parts: a pre-loaded medicated cake 10 and a medical adhesive tape carrier 20. The pre-loaded medicated cake 10 is the core component for exerting the medicinal effect; it is a circular, thin, solid cake. The medical adhesive tape carrier 20 is used to fix and support the medicated cake 10. A ring-shaped raised anti-leakage ring 21 is provided on the adhesive surface of the medical adhesive tape carrier 20. The pre-loaded medicated cake 10 is set and fixed within the central area enclosed by the anti-leakage ring 21. This structure effectively prevents the ointment from leaking outward after softening due to heat. The back of the medical adhesive tape carrier 20 is usually covered with release paper 30 to protect the adhesive surface before use. The diameter of the pre-loaded medicated cake 10 is between 13 mm and 17 mm; in a particularly preferred embodiment, its diameter is 15 mm. Its thickness is between 1 mm and 2 mm.

[0024] The following details one preparation method for this traditional Chinese medicine ointment acupoint patch 100. First, prepare the active powder of the traditional Chinese medicine. Accurately weigh 100g of Asarum, 100g of Euphorbia kansui, 100g of Corydalis yanhusuo, 100g of Sinapis alba, 50g of Pinellia ternata, 40g of camphor, and 10g of borneol. Mix the above medicinal materials and then pulverize them in a pulverizer. Sift the mixture to control the particle size between 100 and 150 mesh to obtain a uniform and fine active powder of the traditional Chinese medicine for later use.

[0025] Next, prepare the herbal oil. Weigh out 100 grams of Angelica sinensis, 100 grams of Rehmannia glutinosa, and 100 grams of Lithospermum erythrorhizon, along with 1200 grams of sesame oil. Soak the Angelica sinensis and Rehmannia glutinosa in the sesame oil for 8 hours, then simmer over low heat until the herbs turn a withered yellow color. Add the Lithospermum erythrorhizon at this point and continue simmering for 5 minutes. Then, filter while hot to remove the dregs. After cooling, the filtrate is the herbal oil.

[0026] Then, prepare an oil-based molding matrix. Measure 80 grams of ginger juice, 10 grams of the prepared herbal oil, and 10 grams of beeswax. Mix the three together and heat in a water bath to 50 degrees Celsius, stirring continuously until the beeswax is completely melted, forming a homogeneous ointment-like matrix.

[0027] The mixture is then mixed and initially shaped. While maintaining the matrix temperature at approximately 50 degrees Celsius, all the prepared active herbal powders are added and stirred to form a uniform, malleable paste. This paste is then rolled into spherical pills approximately 1 cm in diameter.

[0028] The preloaded drug cake 10 is then formed by pressing. The spherical pill is placed into a circular mold and pressed into a circular cake with a thickness of about 1.5 mm and a diameter of about 15 mm, thus obtaining the preloaded drug cake 10.

[0029] Finally, assemble the product. Take a piece of medical PU breathable adhesive tape with an impermeable ring 21 as the medical tape carrier 20. Remove the release paper 30, accurately place the pressed pre-loaded medicine cake 10 in the center of the area enclosed by the impermeable ring 21 and fix it. Then, re-cover with the release paper or directly seal it individually to obtain the finished herbal ointment acupoint patch 100.

[0030] The usage instructions for this acupoint patch (100g) can be found in [link / reference]. Figure 2 To use, first peel off the release paper 30, align the exposed pre-loaded medicated patch 10 with the cleaned target acupoint skin, such as Tian Tu, Tan Zhong, or Da Zhui acupoints, then apply the medical adhesive tape carrier 20 smoothly and press firmly. The anti-leakage ring 21 ensures that the medicated patch 10 is always positioned in the center of the acupoint area. Apply once daily for 4 to 6 hours each time to achieve the effects of warming the lungs, dispelling cold, resolving phlegm, and relieving cough through transdermal absorption. After use, gently peel it off from the edge of the skin; usually, there is no obvious irritation or allergic reaction on the local skin.

[0031] The above embodiments specifically illustrate the structure, preparation process, and usage method of the product of the present invention. Any simple modifications or equivalent substitutions based on the essence of the present invention fall within the protection scope defined by the claims of the present invention.

[0032] The constructions shown in the various exemplary embodiments of the present invention are merely illustrative and should not be construed as limiting the scope of the invention. Although only a few specific embodiments are described in detail in this disclosure, those skilled in the art will understand, upon consulting this disclosure, that numerous variations are possible without materially departing from the novel teachings and advantages of the subject matter described herein. For example, elements shown herein as integrally formed can be constructed by combining multiple parts or components; similarly, the positions of elements can be inverted or otherwise changed according to practical application requirements; and the function, properties, number, or position of discrete elements can be adjusted or optimized accordingly without violating design principles. Therefore, all such variations should be included within the scope of protection of the present invention.

[0033] It should be emphasized that any phrase "device plus function" appearing in the claims of this application is intended to cover the structures described herein for performing the functions, including not only structural equivalents but also equivalent structures capable of achieving the same function. Furthermore, without departing from the scope defined by this invention, those skilled in the art can make various other substitutions, modifications, alterations, and omissions in the design, operating conditions, and overall layout of the exemplary embodiments.

[0034] Furthermore, a full understanding of this invention should recognize that the various embodiments described above are merely exemplary and are intended to illustrate the technical concept and core ideas of the invention. In practical applications, these embodiments may be appropriately adjusted and optimized based on specific design requirements, manufacturing processes, and usage environments. For example, in the actual development of implementation methods, such as in any engineering or design project, numerous specific implementation decisions need to be made. These decisions may involve determining various technical details and process parameters, such as the size, dimensions, structure, shape, and proportion of components, and the setting of parameter values ​​(such as temperature, pressure, etc.). Although such development efforts may be complex and time-consuming, for those skilled in the art who benefit from this disclosure, these development efforts should be considered routine tasks in the design, manufacturing, and production processes without excessive experimentation.

[0035] It should be clarified that the scope of protection of this invention is not limited to the specific embodiments described, but extends to all modifications and variations within the spirit and scope of this invention. In the detailed description of this invention, in order to provide a clear understanding of the technical solutions of this invention, not all features in actual implementations may have been described, because some features may not be directly related to the currently considered best mode of implementation of this invention, or may not be critical factors in realizing this invention. However, those skilled in the art should understand that these features not described in detail can also be selected and applied without departing from the spirit and scope of this invention.

[0036] Finally, it should be noted that although various embodiments of the present invention have been described in detail above, these descriptions are only for illustrating the technical solutions of the present invention and not for limiting it. Those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solutions of the present invention without inventive effort, and such modifications or substitutions should all be covered within the protection scope of the present invention. The true scope and spirit of the present invention should be based on the appended claims, and any technical solution within the scope of the claims should be considered as a protected object of the present invention.

Claims

1. A traditional Chinese medicine ointment / acupoint patch for treating feverish cough, characterized in that, include: A pre-loaded medicine cake and a medical adhesive tape carrier for fixing the medicine cake; The pre-loaded medicated cake is composed of active Chinese medicine powder uniformly dispersed in an oily molding matrix and is carried by the medical adhesive tape carrier; The active powder of traditional Chinese medicine is composed of the following components in parts by weight: 10 parts Asarum, 10 parts Euphorbia kansui, 10 parts Corydalis yanhusuo, 10 parts Sinapis alba, 5 parts Pinellia ternata, 4 parts camphor, and 1 part borneol, and its particle size ranges from 100 mesh to 150 mesh. The oily molding matrix is ​​composed of ginger juice, Chinese herbal oil and beeswax in a mass ratio of 8:1:1, wherein the Chinese herbal oil is an oily substance obtained by frying and extracting angelica, rehmannia and gromwell in sesame oil.

2. The herbal ointment acupoint patch according to claim 1, characterized in that, The medical adhesive tape carrier is a breathable adhesive tape with an impermeable ring, and the pre-loaded drug cake is placed within the area enclosed by the impermeable ring.

3. The herbal ointment acupoint patch according to claim 2, characterized in that, The preloaded drug cake is in the shape of a round, thin cake with a diameter of 13 mm to 17 mm and a thickness of 1 mm to 2 mm.

4. The herbal ointment acupoint patch according to claim 1, characterized in that, In the herbal oil, the mass ratio of Angelica sinensis, Rehmannia glutinosa, and Lithospermum erythrorhizon is 1:1:

1.

5. The herbal ointment acupoint patch according to claim 1, characterized in that, The carrier of the medical breathable adhesive tape is a non-woven adhesive tape or a PU film adhesive tape.

6. A method for preparing a traditional Chinese medicine ointment acupoint patch as described in any one of claims 1 to 5, characterized in that, Includes the following steps: Step 1, Preparation of active powder of traditional Chinese medicine: Weigh each raw material according to the ratio, mix them and then pulverize them to 100 to 150 mesh; Step 2, prepare the Chinese herbal oil: Soak Angelica sinensis and Rehmannia glutinosa in sesame oil for 6-12 hours, heat until the herbs turn yellow, add Lithospermum erythrorhizon and continue to fry for 3-7 minutes, filter, and cool the filtrate; Step 3, prepare the oily molding matrix: mix ginger juice, the Chinese herbal oil obtained in step 2 and beeswax in a mass ratio of 8:1:1, heat until the beeswax melts and stir evenly; Step 4, Mixing and initial shaping: Add the active Chinese medicine powder obtained in Step 1 to the oily molding matrix obtained in Step 3, mix evenly, and make spherical pills with a diameter of 0.8cm to 1.2cm. Step 5, pressing the spherical pills into round cakes with a thickness of 1mm to 2mm; Step 6, Assemble the patch: Place the round medicated cake obtained in step 5 into the seepage-proof ring of the medical breathable adhesive tape carrier to make the Chinese herbal ointment acupoint patch.

7. The method according to claim 6, characterized in that, In step two, the amount of sesame oil used is 3-5 times the total mass of the angelica, rehmannia, and gromwell.

8. The method according to claim 6, characterized in that, In step four, the blending is carried out at a temperature of 45°C to 55°C.

9. The method according to claim 6, characterized in that, In step six, the medical breathable adhesive tape carrier is a non-woven adhesive tape or a PU film adhesive tape.

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