Use of antimicrobial peptides in the preparation of skin care products

By preparing antimicrobial peptides with specific amino acid sequences, skin care products are made, which solves the problems of poor absorption, high drug resistance, and many adverse reactions in the treatment of acne, inflammation and dandruff in existing technologies. This achieves the effect of highly inhibiting Propionibacterium acnes and Malassezia, and relieving acne, skin inflammation and dandruff.

CN122297635APending Publication Date: 2026-06-30BLOOMAGE BIOTECHNOLOGY (HAINAN) CO LTD +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
BLOOMAGE BIOTECHNOLOGY (HAINAN) CO LTD
Filing Date
2024-12-30
Publication Date
2026-06-30

AI Technical Summary

Technical Problem

Existing technologies for treating acne, inflammation, and dandruff suffer from problems such as poor absorption, high drug resistance, numerous adverse reactions, long treatment courses, and high costs. Traditional antibiotics and Chinese medicine treatments have limited effectiveness.

Method used

Skin care products are prepared using antimicrobial peptides with specific amino acid sequences (such as SEQ ID NO:1-LX1X2YYX3YISLFLRRKCRI) to inhibit Propionibacterium acnes and Malassezia. The preparation method includes modification of the N-terminus and/or C-terminus of the amino acid sequence and is a protein activity function prediction and solid-phase synthesis method.

Benefits of technology

The antimicrobial peptides have significant antibacterial effects against Propionibacterium acnes and Malassezia, with an inhibition rate of ≥99.5%. They exhibit stable antibacterial effects at different concentrations and can effectively alleviate problems such as acne, skin inflammation, and dandruff.

✦ Generated by Eureka AI based on patent content.

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Abstract

This application provides the use of an antimicrobial peptide in the preparation of skin care products. The antimicrobial peptide of this application can effectively inhibit *Propionibacterium acnes* and *Malassezia*, thereby preventing skin problems such as acne, skin inflammation, and dandruff caused by the overgrowth of these two bacteria. Therefore, the antimicrobial peptide of this application has skin care uses in inhibiting acne, relieving skin inflammation such as folliculitis, pityriasis versicolor, and seborrheic dermatitis, and in inhibiting dandruff, and has significant practical value.
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